An empirical framework for binary interactome mapping (2009)
Venkatesan, Kavitha, Rual, Jean-Francois, Vazquez, Alexei, Stelzl, Ulrich, Lemmens, Irma, Hirozane-Kishikawa, Tomoko, ...
Several attempts have been made to systematically map protein-protein interaction, or 'interactome', networks. However, it remains difficult to assess the quality and coverage of existing data sets....
Simonis, Nicolas, Rual, Jean-Francois, Carvunis, Anne-Ruxandra, Tasan, Murat, Lemmens, Irma, Hirozane-Kishikawa, Tomoko, ...
Abstract: To provide accurate biological hypotheses and elucidate global properties of cellular networks, systematic identification of protein-protein interactions must meet high quality standards....
A protein domain-based interactome network for C. elegans early embryogenesis (2008)
Boxem, Mike, Maliga, Zoltan, Klitgord, Niels, Li, Na, Lemmens, Irma, Mana, Miyeko, ...
Many protein-protein interactions are mediated through independently folding modular domains. Proteome-wide efforts to model protein-protein interaction or "interactome" networks have largely ignored...
Revisiting the Saccharomyces cerevisiae predicted ORFeome (2008)
Li, Qian-Ru, Carvunis, Anne-Ruxandra, Yu, Haiyuan, Han, Jing-Dong J., Zhong, Quan, Simonis, Nicolas, ...
Accurately defining the coding potential of an organism, i.e., all protein-encoding open reading frames (ORFs) or “ORFeome,” is a prerequisite to fully understand its biology. ORFeome annotation...
Confirmation of Organized Modularity in the Yeast Interactome (2007)
Nicolas Bertin, Nicolas Simonis, Denis Dupuy, Michael E. Cusick, Hunter B. Fraser, ...
Transcriptional regulation of protein complexes in yeast (2004)
Simonis, Nicolas, Van Helden, Jacques, Cohen, George N, Wodak, Shoshana J
Abstract Background Multiprotein complexes play an essential role in many cellular processes. But our knowledge of the mechanism of their formation, regulation and lifetimes is very limited. We...
Transcriptional regulation of protein complexes in yeast
Simonis, Nicolas, Van Helden, Jacques, Cohen, George N, Wodak, Shoshana J
This study shows that only a small fraction of yeast protein complexes are coregulated at the transcriptional level.
Transcriptional regulation of protein complexes in yeast
Simonis, Nicolas, Van Helden, Jacques, Cohen, George N, Wodak, Shoshana J
This study shows that only a small fraction of yeast protein complexes are coregulated at the transcriptional level.
Confirmation of Organized Modularity in the Yeast Interactome
Bertin, Nicolas, Simonis, Nicolas, Dupuy, Denis, Cusick, Michael E, Han, Jing-Dong J, Fraser, Hunter B, ...
Revisiting the Saccharomyces cerevisiae predicted ORFeome
Li, Qian-Ru, Carvunis, Anne-Ruxandra, Yu, Haiyuan, Han, Jing-Dong J., Zhong, Quan, Simonis, Nicolas, ...
Accurately defining the coding potential of an organism, i.e., all protein-encoding open reading frames (ORFs) or “ORFeome,” is a prerequisite to fully understand its biology. ORFeome annotation...