Nikki M. Parrish

Characterization of fatty acid biosynthesis in mycobacteria as an approach to elucidate potential targets for antimycobacterial chemotherapeutic agents--[microform] /--by Nikki M. Parrish. (1999)

Parrish, Nikki M.

Vita.

Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis (1999)

Parrish, Nikki M., Kuhajda, Francis P., Heine, Henry S., Bishai, William R., Dick, James D.

Cerulenin is a potent inhibitor of fatty acid synthase (FAS) in a variety of prokaryotic and eukaryotic cells. Using a standardized mycobacterial susceptibility test, we have observed that cerulenin...

In Vitro Activity of a Novel Antimycobacterial Compound, N-Octanesulfonylacetamide, and Its Effects on Lipid and Mycolic Acid Synthesis

Parrish, Nikki M., Houston, Todd, Jones, Paul B., Townsend, Craig, Dick, James D.

β-Sulfonyl carboxamides have been proposed to serve as transition-state analogues of the β-ketoacyl synthase reaction involved in fatty acid elongation. We tested the efficacy of...

In Vitro Activity of a Novel Antimycobacterial Compound, N-Octanesulfonylacetamide, and Its Effects on Lipid and Mycolic Acid Synthesis

Parrish, Nikki M., Houston, Todd, Jones, Paul B., Townsend, Craig, Dick, James D.

β-Sulfonyl carboxamides have been proposed to serve as transition-state analogues of the β-ketoacyl synthase reaction involved in fatty acid elongation. We tested the efficacy of...