Nikolaus Gassler

First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome (2008)

Kapeller, Johannes, Houghton, Lesley A., Mönnikes, Hubert, Walstab, Jutta, Möller, Dorothee, Bönisch, Heinz, ...

Diarrhea predominant irritable bowel syndrome (IBS-D) is a complex disorder related to dysfunctions in the serotonergic system. As cis-regulatory variants can play a role in the etiology of complex...

DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease (2007)

Renner, Marcus, Bergmann, Gaby, Krebs, Inge, End, Caroline, Lyer, Stefan, Hilberg, Frank, ...

BACKGROUND & AIMS: Impaired mucosal defense plays an important role in the pathogenesis of Crohn's disease (CD), one of the main subtypes of inflammatory bowel disease (IBD). Deleted in malignant...

Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant (2007)

Müller, Hanna, End, Caroline, Renner, Marcus, Helmke, Burkhard M, Gassler, Nikolaus, Weiss, Christel, ...

Abstract Background Deleted in Malignant Brain Tumors 1 (DMBT1) is a secreted scavenger receptor cysteine-rich protein that binds various bacteria and is thought to participate in innate pulmonary...

Cloning of a novel neuronally expressed orphan G−protein−coupled receptor which is up−regulated by erythropoietin, interacts with microtubule−associated protein 1b and colocalizes with the 5−hydroxytryptamine 2a receptor (2004)

Maurer,Martin H., Grunewald,Sylvia, Gassler,Nikolaus, Rossner,Moritz, Propst,Friedrich, Würz,Rebecca, ...

G−protein−coupled receptors (GPCRs) are the largest group of cell surface molecules involved in signal transduction and are receptors for a wide variety of stimuli ranging from light, calcium and...

Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor (2004)

Maurer,Martin H., Grünewald,Sylvia, Gassler,Nikolaus, Rossner,Moritz, Propst,Friedrich, Würz,Rebecca, ...

Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor (2004)

Maurer, Martin H., Grünewald, Sylvia, Gassler, Nikolaus, Rossner, Moritz, Propst, Friedrich, Würz, Rebecca, ...

Cloning of a novel neuronally expressed orphan G−protein−coupled receptor which is up−regulated by erythropoietin, interacts with microtubule−associated protein 1b and colocalizes with the 5−hydroxytryptamine 2a receptor (2004)

Maurer, Martin H., Grunewald, Sylvia, Gassler, Nikolaus, Rossner, Moritz, Propst, Friedrich, Würz, Rebecca, ...

G−protein−coupled receptors (GPCRs) are the largest group of cell surface molecules involved in signal transduction and are receptors for a wide variety of stimuli ranging from light, calcium and...

The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis

Schneider, Armin, Krüger, Carola, Steigleder, Tobias, Weber, Daniela, Pitzer, Claudia, Laage, Rico, ...

G-CSF is a potent hematopoietic factor that enhances survival and drives differentiation of myeloid lineage cells, resulting in the generation of neutrophilic granulocytes. Here, we show that G-CSF...

The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis

Schneider, Armin, Krüger, Carola, Steigleder, Tobias, Weber, Daniela, Pitzer, Claudia, Laage, Rico, ...

G-CSF is a potent hematopoietic factor that enhances survival and drives differentiation of myeloid lineage cells, resulting in the generation of neutrophilic granulocytes. Here, we show that G-CSF...

Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant

Müller, Hanna, End, Caroline, Renner, Marcus, Helmke, Burkhard M, Gassler, Nikolaus, Weiss, Christel, ...