A cyclosporine-sensitive psoriasis-like disease produced in Tie2 transgenic mice. (2005)
Voskas, Daniel, Jones, Nina, Van Slyke, Paul, Sturk, Celina, Chang, Wing, Haninec, Alex, ...
Psoriasis is a common, persistent skin disorder characterized by recurrent erythematous lesions thought to arise as a result of inflammatory cell infiltration and activation of keratinocyte...
Teichert-Kuliszewska, Krystyna, Maisonpierre, Peter C., Jones, Nina, Campbell, Andrew I.M., Master, Zubin, Bendeck, Michelle P., ...
The endothelial cell (EC) specific tyrosine kinase receptor, Tie2, interacts with at least two ligands, angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2). Ang1 stimulates Tie2 receptor...
grantor: University of Toronto
ORBSCAN Accuracy in Measuring Corneal Surface Elevation (1998)
Salmon, Thomas O., Van DePol, Corina, Jones, Nina
The Surgeon General has recently authorized individuals who have had corneal refractive surgery entry, by waiver, into the services. Since Army aviators already operate under less than optimal visual...
Master, Zubin, Jones, Nina, Tran, Jennifer, Jones, Jamie, Kerbel, Robert S., Dumont, Daniel J.
Tek/Tie-2 is an endothelial cell (EC)-specific receptor tyrosine kinase that plays a critical role in angiogenesis via its regulation by the angiopoietin family of growth factor ligands....
Jones, Nina, Chen, Stephen H., Sturk, Celina, Master, Zubin, Tran, Jennifer, Kerbel, Robert S., ...
Tie2/Tek is an endothelial cell receptor tyrosine kinase that induces signal transduction pathways involved in cell migration upon angiopoietin-1 (Ang1) stimulation. To address the importance of the...
Kimura, Yuki, Jones, Nina, Klüppel, Michael, Hirashima, Masanori, Tachibana, Kazunobu, Cohn, Jason B., ...
Loss-of-function mutations in the murine dominant white spotting/c-kit locus affect a diverse array of biological processes and cell lineages and cause a range of phenotypes, including severe anemia,...
Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function
Jones, Nina, Voskas, Daniel, Master, Zubin, Sarao, Renu, Jones, Jamie, Dumont, Daniel J.
Disruption of the signaling pathways mediated by the receptor tyrosine kinase Tek/Tie2 has shown that this receptor plays a pivotal role in vascularization of the developing embryo. In this report,...
Selective Role of a Distinct Tyrosine Residue on Tie2 in Heart Development and Early Hematopoiesis
Tachibana, Kazunobu, Jones, Nina, Dumont, Daniel J., Puri, Mira C., Bernstein, Alan
The development of the cardiovascular system and the development of the early hematopoietic systems are closely related, and both require signaling through the Tie2 receptor tyrosine kinase. Although...
Master, Zubin, Jones, Nina, Tran, Jennifer, Jones, Jamie, Kerbel, Robert S., Dumont, Daniel J.
Tek/Tie-2 is an endothelial cell (EC)-specific receptor tyrosine kinase that plays a critical role in angiogenesis via its regulation by the angiopoietin family of growth factor ligands....
Jones, Nina, Chen, Stephen H., Sturk, Celina, Master, Zubin, Tran, Jennifer, Kerbel, Robert S., ...
Tie2/Tek is an endothelial cell receptor tyrosine kinase that induces signal transduction pathways involved in cell migration upon angiopoietin-1 (Ang1) stimulation. To address the importance of the...
Kimura, Yuki, Jones, Nina, Klüppel, Michael, Hirashima, Masanori, Tachibana, Kazunobu, Cohn, Jason B., ...
Loss-of-function mutations in the murine dominant white spotting/c-kit locus affect a diverse array of biological processes and cell lineages and cause a range of phenotypes, including severe anemia,...
Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function
Jones, Nina, Voskas, Daniel, Master, Zubin, Sarao, Renu, Jones, Jamie, Dumont, Daniel J.
Disruption of the signaling pathways mediated by the receptor tyrosine kinase Tek/Tie2 has shown that this receptor plays a pivotal role in vascularization of the developing embryo. In this report,...
Selective Role of a Distinct Tyrosine Residue on Tie2 in Heart Development and Early Hematopoiesis
Tachibana, Kazunobu, Jones, Nina, Dumont, Daniel J., Puri, Mira C., Bernstein, Alan
The development of the cardiovascular system and the development of the early hematopoietic systems are closely related, and both require signaling through the Tie2 receptor tyrosine kinase. Although...
Smith, Matthew J., Hardy, W. Rod, Murphy, James M., Jones, Nina, Pawson, Tony
Modular interaction domains that recognize peptide motifs in target proteins can impart selectivity in signaling pathways. Phosphotyrosine binding (PTB) domains are components of cytoplasmic docking...
A Cyclosporine-Sensitive Psoriasis-Like Disease Produced in Tie2 Transgenic Mice
Voskas, Daniel, Jones, Nina, Van Slyke, Paul, Sturk, Celina, Chang, Wing, Haninec, Alex, ...
Psoriasis is a common, persistent skin disorder characterized by recurrent erythematous lesions thought to arise as a result of inflammatory cell infiltration and activation of keratinocyte...
Angiogenic Actions of Angiopoietin-1 Require Endothelium-Derived Nitric Oxide
Babaei, Saeid, Teichert-Kuliszewska, Krystyna, Zhang, Qiuwang, Jones, Nina, Dumont, Daniel J., Stewart, Duncan J.
Angiopoietin1 (Ang1) is a novel angiogenic factor with important actions on endothelial cell (EC) differentiation and vascular maturation. Ang1 has been shown to prevent EC apoptosis through...
Analysis of a Shc Family Adaptor Protein, ShcD/Shc4, That Associates with Muscle-Specific Kinase▿
Jones, Nina, Hardy, W. Rod, Friese, Matthew B., Jorgensen, Claus, Smith, Matthew J., Woody, Neil M., ...
Shc family proteins serve as phosphotyrosine adaptor molecules in various receptor-mediated signaling pathways. In mammals, three distinct Shc genes have been described that encode proteins...
Blasutig, Ivan M., New, Laura A., Thanabalasuriar, Ajitha, Dayarathna, Thamara K., Goudreault, Marilyn, Quaggin, Susan E., ...
We have analyzed the means by which the Nck family of adaptor proteins couples adhesion proteins to actin reorganization. The nephrin adhesion protein is essential for the formation of actin-based...