Functional analysis of Cdk7-interacting proteins Mat1 and Hint in model organisms / (2002)
Diss. -- Helsingin yliopisto.
Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1
Rossi, Derrick J., Londesborough, Anou, Korsisaari, Nina, Pihlak, Arno, Lehtonen, Eero, Henkemeyer, Mark, ...
The trimeric Cdk7–cyclin H–Mat1 complex comprises the kinase subunit of basal transcription factor TFIIH and has been shown to function as a cyclin-dependent kinase (Cdk)-activating kinase....
Induction of cyclooxygenase-2 in a mouse model of Peutz–Jeghers polyposis
Rossi, Derrick J., Ylikorkala, Antti, Korsisaari, Nina, Salovaara, Reijo, Luukko, Keijo, Launonen, Virpi, ...
Inactivating germ-line mutations of LKB1 lead to Peutz–Jeghers syndrome (PJS). We have generated mice heterozygous for a targeted inactivating allele of Lkb1 and found that they develop severe...
The Histidine Triad Protein Hint Is Not Required for Murine Development or Cdk7 Function
Korsisaari, Nina, Rossi, Derrick J., Luukko, Keijo, Huebner, Kay, Henkemeyer, Mark, Mäkelä, Tomi P.
The histidine triad (HIT) protein Hint has been found to associate with mammalian Cdk7, as well as to interact both physically and genetically with the budding yeast Cdk7 homologue Kin28. To study...
Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1
Rossi, Derrick J., Londesborough, Anou, Korsisaari, Nina, Pihlak, Arno, Lehtonen, Eero, Henkemeyer, Mark, ...
The trimeric Cdk7–cyclin H–Mat1 complex comprises the kinase subunit of basal transcription factor TFIIH and has been shown to function as a cyclin-dependent kinase (Cdk)-activating kinase....
Induction of cyclooxygenase-2 in a mouse model of Peutz–Jeghers polyposis
Rossi, Derrick J., Ylikorkala, Antti, Korsisaari, Nina, Salovaara, Reijo, Luukko, Keijo, Launonen, Virpi, ...
Inactivating germ-line mutations of LKB1 lead to Peutz–Jeghers syndrome (PJS). We have generated mice heterozygous for a targeted inactivating allele of Lkb1 and found that they develop severe...
The Histidine Triad Protein Hint Is Not Required for Murine Development or Cdk7 Function
Korsisaari, Nina, Rossi, Derrick J., Luukko, Keijo, Huebner, Kay, Henkemeyer, Mark, Mäkelä, Tomi P.
The histidine triad (HIT) protein Hint has been found to associate with mammalian Cdk7, as well as to interact both physically and genetically with the budding yeast Cdk7 homologue Kin28. To study...
Korsisaari, Nina, Kasman, Ian M., Forrest, William F., Pal, Navneet, Bai, Wei, Fuh, Germaine, ...
Anti-VEGF-A monoclonal antibodies, in combination with chemotherapy, result in a survival benefit in patients with metastatic colorectal and non-small cell lung cancer, but little is known regarding...