Nobuo Koike

In vivo time-course of receptor binding in the parathyroid gland of the vitamin D analogue [3H]1,25-dihydroxy-22-oxavitamin D3 compared with [3H]1,25-dihydroxyvitamin D3, determined by micro-autoradiography (2002)

Koike, Nobuo, Hayakawa, Naohiko, Tokuda, Kazuo, Nishimiya, Kazuhiro, Saito, Kimitoshi, Stumpf, Walter E.

1,25-Dihydroxy-22-oxavitamin D3 (22-oxacalcitriol, OCT), is a new synthetic analogue of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3, calcitriol), to be used in the treatment...

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

Serada, Satoshi, Fujimoto, Minoru, Mihara, Masahiko, Koike, Nobuo, Ohsugi, Yoshiyuki, Nomura, Shintaro, ...

The development of Th17 cells is a key event in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), a murine model of human multiple sclerosis (MS). Previous studies have...