Establishment of the need for oestrogen during implantation in non-human primates (2007)
Rao, AJ, Ramachandra, SG, Ramesh, V, Krishnamurthy, HN, Ravindranath, N, Moudgal, NR
Deprivation of oestrogen during post-ovulatory mated cycles in proven fertile female bonnet monkeys by tamoxifen, aromatase inhibitor or oestrogen antiserum resulted in inhibition of pregnancy...
Kumar, Prasanna KM, Krishnamurthy, H, Krishnamurthy, HN, Shetty, G, Moudgal, NR
The efficacy of 200 mg of norethisterone enanthate (NET-EN) and 2 mg of estradiol valerate (E-VAL) combination to suppress FSH/LH secretion and testicular function in adult volunteer men has been...
Moudgal, NR, Ravindranath, N, Murthy, GS, Dighe, RR, Aravindan, GR, Martin, F
A group of ten healthy fertile adult male bonnet monkeys were actively immunized using procedures acceptable for human use with pure follicle-stimulating hormone (oFSH) isolated from sheep...
Dighe, R, Murthy, GS, Moudgal, NR
Two novel and simple methods have been developed for detecting monoclonal antibodies (MAbs) with identical epitope specificities from a large population of MAbs against human chorionic gonadotropin...
Rao, AJ, Rani, CS, Ravindranath, N, Moudgal, NR
Adult male bonnet monkeys maintained under regulated light:dark conditions exhibit a nycthemeral surge of testosterone. The present study attempts to det. the effect of administration of drugs that...
This review of the immunobiology of FSH and inhibin in animal research studies emphasizes unique behaviors of their antibodies potentially applicable to contraceptive vaccines. FSH is a di-peptide...
Aravindan, GR, Ravindranath, N, Gopalakrishnan, K, Moudgal, NR
Testicular germ cell populations of biopsies from 32 male bonnet monkeys in 5 different age groups were quantitated in a flow cytometer after labelling of germ cell DNA with the specific...
Ravindranath, N, Rani, Sheela CS, Martin, F, Moudgal, NR
Cyclic monkeys were deprived of FSH for specific periods on different days of the follicular phase by injecting them with minimal doses of an FSH antiserum characterized for specificity and...
Biochemical and histological validation of a model to study follicular atresia in rats (1989)
A model system to study the biochemical mechanism of follicular atresia in rats [Dhanasekaran et al. 1983] was characterized using histological and biochemical correlates. PMSG and PMSG antiserum...
The mechanism of ‘down regulation’ of luteinizing hormone receptors was investigated in pseudopregnant rats using a modified radioimmunoassay capable of measuring endogenous tissue-bound hormone....
Administration of tamoxifen orally (3 mg/kg/day) during the post-ovulatory period from Days 16 to 20 or from Days 18 to 30 of female bonnet monkeys mated between Days 9 and 14 of the cycle resulted...
Immunological crossreactivity of the antisera to purified hormones (1987)
Antisera to ovine follicle stimulating hormone free of ovine lutinising hormone contamination has been obtained in monkeys. These antisera have been shown to be able to crossreact with ovine...
Use of epoxysepharose for protein immobilisation (1986)
Epoxy Sepharose, an activated affinity matrix which has been used for immobilisation of carbohydrates has been tried for immobilisation of proteins. Under normal conditions of coupling at neutral or...
Studies on ovarian quiescence in the lactating bonnet monkey (Macaca radiata) (1985)
Moudgal, NR, Maneckjee, R, Srinath, BR, Ramasharma, K
Lactating bonnet monkeys were used as a model to understand the mechanism of ovarian quiescence during lactation. The ovary of the bonnet monkey in the 3rd month of lactation responds well to...
Moudgal, NR, Martin, F, Kotagi, SG, Sairam, MR, Ravindranath, N, Rao, AJ, ...
Long-term active immunization of nonhuman primates (bonnet monkey) with ovine FSH [9002-68-0] resulted in continued testicular dysfunction leading to acute oligospermia or azoospermia. Since...
Antisera (a/s) raised to individual \alpha - and \delta -subunits of human chorionic gonadotropin (hCG) [9002-61-3] were characterized for specificity and used to study the disposition of the 2...
Dhanasekaran, N, Rani, Sheela CS, Moudgal, NR
The changes that occur during follicular growth and atresia in the lysosomal enzyme activities and in gonadotropin receptors of isolated granulosa cells were studied. At different intervals after an...
Murthy, Shashidhara HM, Moudgal, NR
Inhibin (follicle stimulating hormone suppressing factor) isolated from ovine testes has been characterized for its biological activity using a variety of tests. The bioassay used — inhibition of...