Nurit Gal-Mark

Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome (2008)

Sela, Noa, Mersch, Britta, Gal-Mark, Nurit, Lev-Maor, Galit, Ast, Gil

Background: Transposed elements (TEs) have a substantial impact on mammalian evolution and are involved in numerous genetic diseases. We compared the impact of TEs on the human transcriptome and the...

Alternative splicing of Alu exons--two arms are better than one (2008)

Gal-Mark, Nurit, Schwartz, Schraga, Ast, Gil

Alus, primate-specific retroelements, are the most abundant repetitive elements in the human genome. They are composed of two related but distinct monomers, left and right arms. Intronic Alu elements...

Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome (2007)

Sela, Noa, Mersch, Britta, Gal-Mark, Nurit, Lev-Maor, Galit, Hotz-Wagenblatt, Agnes, Ast, Gil

Abstract Background Transposed elements (TEs) have a substantial impact on mammalian evolution and are involved in numerous genetic diseases. We compared the impact of TEs on the human transcriptome...

Alternative splicing of Alu exons—two arms are better than one

Gal-Mark, Nurit, Schwartz, Schraga, Ast, Gil

Alus, primate-specific retroelements, are the most abundant repetitive elements in the human genome. They are composed of two related but distinct monomers, left and right arms. Intronic Alu elements...

Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome

Sela, Noa, Mersch, Britta, Gal-Mark, Nurit, Lev-Maor, Galit, Hotz-Wagenblatt, Agnes, Ast, Gil

Analysis of transposed elements in the human and mouse genomes reveals many effects on the transcriptomes, including a higher level of exonization of Alu elements than other elements.

Alu Exonization Events Reveal Features Required for Precise Recognition of Exons by the Splicing Machinery

Schwartz, Schraga, Gal-Mark, Nurit, Kfir, Nir, Oren, Ram, Kim, Eddo, Ast, Gil

Despite decades of research, the question of how the mRNA splicing machinery precisely identifies short exonic islands within the vast intronic oceans remains to a large extent obscure. In this...

The Pivotal Roles of TIA Proteins in 5′ Splice-Site Selection of Alu Exons and Across Evolution

Gal-Mark, Nurit, Schwartz, Schraga, Ram, Oren, Eyras, Eduardo, Ast, Gil

More than 5% of alternatively spliced internal exons in the human genome are derived from Alu elements in a process termed exonization. Alus are comprised of two homologous arms separated by an...