Guidelines for resection of colorectal cancer liver metastases (2006)
Garden, O.J., Rees, M., Poston, G.J., Mirza, D., Saunders, M., Ledermann, J., ...
Simmonds, P.C., Primrose, J.N., Colquitt, J.L., Garden, O.J., Poston, G.J., Rees, M.
No consensus on the indications for surgical resection of colorectal liver metastases exists. This systematic review has been undertaken to assess the published evidence for its efficacy and safety...
Walsh, T. S., Garden, O. J., Lee, A.
Reperfusion of the liver during transplantation can cause cardiovascular changes such as systemic vasodilatation, pulmonary hypertension and cardiac dysfunction. We have previously demonstrated a...
J. M. Ferguson, K. R. Palmer, O. J. Garden, D. N. Redhead
We present a case of recurrent variceal bleeding due to subtotal occlusion of the splenoportal junction by a pancreatic carcinoma. This was effectively treated by transhepatic venous angioplasty and...
Liver and Pancreatic Resection in the Elderly (1997)
Background: Liver resection, or pancreaticoduodenectomy, has traditionally been thought to have a high morbidity and. mortality rate among the elderly. Recent improvements in surgical and anesthetic...
Cholecystobronchocolic Fistula: A Late Complication of Biliary Sepsis (1994)
D. A. Collie, D. N. Redhead, O. J. Garden
A case of a 48 year old woman presenting with bilioptysis due to a cholecystobronchocolic fistula is reported. Bilioptysis is a rare complication of biliary fistulae, with a high mortality due to...
Cholangitis and Budd Chiari Syndrome as Complications of Simple Cystic Liver Disease (1993)
A. J. Johnstone, L. W. Turnbull, P. L. Allan, O. J. Garden
We report the case of a 63 year old woman who developed the complications of cholangitis and Budd Chiari syndrome secondary to polycystic disease of the liver. The two complications were not present...
Ruth F. Mckee, O. J. Garden, J. R. Anderson, D. C. Carter
Forty endoscopically proven active variceal bleeds were entered in a prospective trial comparing oesophageal tamponade with SMS 201-995 infusion.Oesophageal tamponade controlled 19 of 20 bleeds over...
Fibronectin as a Prognostic Indicator in Portal Hypertension (1992)
Ruth F. Mckee, D. P. Maharaj, O. J. Garden, D. C. Carter
Plasma fibronectin levels were measured in 33 patients with portal hypertension and c6mpared with modified Child’s grading and a previously described prognostic index. Outcome at one year from...
Tailoring the management of nonparasitic liver cysts.
Martin, I J, McKinley, A J, Currie, E J, Holmes, P, Garden, O J
OBJECTIVE: To determine the optimal management of symptomatic non-parasitic liver cysts. SUMMARY BACKGROUND DATA: Management options for symptomatic nonparasitic liver cysts lack substantiation...
O'Riordain, M G, Fearon, K C, Ross, J A, Rogers, P, Falconer, J S, Bartolo, D C, ...
OBJECTIVE: The authors determined the effect of glutamine-supplementation of TPN on postoperative peripheral blood T-cell response and proinflammatory cytokine production in patients undergoing...
Superior staging of liver tumors with laparoscopy and laparoscopic ultrasound.
John, T G, Greig, J D, Crosbie, J L, Miles, W F, Garden, O J
OBJECTIVE. The authors describe the technique of staging laparoscopy with laparoscopic contact ultrasonography in the preoperative assessment of patients with liver tumors, and assess its impact on...
John, T G, Greig, J D, Carter, D C, Garden, O J
OBJECTIVE: The authors performed a prospective evaluation of staging laparoscopy with laparoscopic ultrasonography in predicting surgical resectability in patients with carcinomas of the pancreatic...
Major hepatic resection under total vascular exclusion.
Bismuth, H, Castaing, D, Garden, O J
Over a 9-year period, major resection was successfully performed on 51 occasions with total vascular exclusion using supra- and infrahepatic caval and portal vein clamping. The main indications for...
Segmental liver resection using ultrasound-guided selective portal venous occlusion.
Castaing, D, Garden, O J, Bismuth, H
Anatomical segmental resection of small hepatic lesions using operative ultrasonography is improved by selective intrahepatic portal venous occlusion. The technique was successfully performed in 15...
Tailoring the management of nonparasitic liver cysts.
Martin, I J, McKinley, A J, Currie, E J, Holmes, P, Garden, O J
OBJECTIVE: To determine the optimal management of symptomatic non-parasitic liver cysts. SUMMARY BACKGROUND DATA: Management options for symptomatic nonparasitic liver cysts lack substantiation...
O'Riordain, M G, Fearon, K C, Ross, J A, Rogers, P, Falconer, J S, Bartolo, D C, ...
OBJECTIVE: The authors determined the effect of glutamine-supplementation of TPN on postoperative peripheral blood T-cell response and proinflammatory cytokine production in patients undergoing...
Superior staging of liver tumors with laparoscopy and laparoscopic ultrasound.
John, T G, Greig, J D, Crosbie, J L, Miles, W F, Garden, O J
OBJECTIVE. The authors describe the technique of staging laparoscopy with laparoscopic contact ultrasonography in the preoperative assessment of patients with liver tumors, and assess its impact on...
John, T G, Greig, J D, Carter, D C, Garden, O J
OBJECTIVE: The authors performed a prospective evaluation of staging laparoscopy with laparoscopic ultrasonography in predicting surgical resectability in patients with carcinomas of the pancreatic...
Major hepatic resection under total vascular exclusion.
Bismuth, H, Castaing, D, Garden, O J
Over a 9-year period, major resection was successfully performed on 51 occasions with total vascular exclusion using supra- and infrahepatic caval and portal vein clamping. The main indications for...
Segmental liver resection using ultrasound-guided selective portal venous occlusion.
Castaing, D, Garden, O J, Bismuth, H
Anatomical segmental resection of small hepatic lesions using operative ultrasonography is improved by selective intrahepatic portal venous occlusion. The technique was successfully performed in 15...
Haydon, G H, Jarvis, L M, Simmonds, P, Harrison, D J, Garden, O J, Hayes, P C
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers in the world. The geographical prevalence varies considerably in different countries and Scotland is regarded as an area...
Plasma concentrations of endogenous heparinoids in portal hypertension.
McKee, R F, Hodson, S, Dawes, J, Garden, O J, Carter, D C
Bleeding as a complication of liver disease can occur in the absence of recognised haemostatic defects. It is now possible to measure the concentration of endogenous heparinoid substances in the...
Cholangiocarcinoma arising after biliary-enteric drainage procedures for benign disease
Bettschart, V, Clayton, R A E, Parks, R W, Garden, O J, Bellamy, C O C
Schindl, M J, Redhead, D N, Fearon, K C H, Garden, O J, Wigmore, S J
Background and aims: Major liver resection incurs a risk of postoperative liver dysfunction and infection and there is a lack of objective evidence relating residual liver volume to these...
Surgical palliation for unresectable hilar cholangiocarcinoma
Connor, S., Wigmore, S. J., Madhavan, K. K., Parks, R. W., Garden, O. J.
The majority of patients who present with hilar cholangiocarcinoma will have incurable disease and require only palliation. Efficient relief of disabling symptoms is required with minimal morbidity...
Preoperative lymphocyte count as a prognostic factor in resected pancreatic ductal adenocarcinoma
Clark, E.J., Connor, S., Taylor, M.A., Madhavan, K.K., Garden, O.J., Parks, R.W.
Background and aims. Recognized prognostic factors for resected pancreatic ductal adenocarcinoma (PDAC) include tumour size, differentiation, resection margin involvement and lymph node metastases. A...
Clark, E., Connor, S., Taylor, M. A., Hendry, C. L., Madhavan, K. K., Garden, O. J., ...
Background and aims: Pancreaticoduodenectomy (PD) is a major operative intervention performed most commonly for malignancy in the head of pancreas. The aim of this study was to evaluate the...
Results of decompression surgery for pain in chronic pancreatitis
Terrace, J.D., Paterson, H.M., Garden, O.J., Parks, R.W., Madhavan, K.K.
Introduction. A vast majority of patients with chronic pancreatitis require regular opiate/opioid analgesia and recurrent hospital admission for pain. However, the role and timing of operative...
Cholecystobronchocolic Fistula: A Late Complication of Biliary Sepsis
Collie, D. A., Redhead, D. N., Garden, O. J.
A case of a 48 year old woman presenting with bilioptysis due to a cholecystobronchocolic fistula is reported. Bilioptysis is a rare complication of biliary fistulae, with a high mortality due to...
Ferguson, J. M., Palmer, K. R., Garden, O. J., Redhead, D. N.
We present a case of recurrent variceal bleeding due to subtotal occlusion of the splenoportal junction by a pancreatic carcinoma. This was effectively treated by transhepatic venous angioplasty and...
Liver and Pancreatic Resection in the Elderly
Background: Liver resection, or pancreaticoduodenectomy, has traditionally been thought to have a high morbidity and. mortality rate among the elderly. Recent improvements in surgical and anesthetic...
Fibronectin as a Prognostic Indicator in Portal Hypertension
Mckee, Ruth F., Maharaj, D. P., Garden, O. J., Carter, D. C.
Plasma fibronectin levels were measured in 33 patients with portal hypertension and c6mpared with modified Child’s grading and a previously described prognostic index. Outcome at one year from...
A Comparison of Sms 201-995 and Oesophageal Tamponade in the Control of Acute Variceal Haemorrhage
Mckee, Ruth F., Garden, O. J., Anderson, J. R., Carter, D. C.
Forty endoscopically proven active variceal bleeds were entered in a prospective trial comparing oesophageal tamponade with SMS 201-995 infusion.
Cholangitis and Budd Chiari Syndrome as Complications of Simple Cystic Liver Disease
Johnstone, A. J., Turnbull, L. W., Allan, P. L., Garden, O. J.
We report the case of a 63 year old woman who developed the complications of cholangitis and Budd Chiari syndrome secondary to polycystic disease of the liver. The two complications were not present...
Role of the surgical trainee in upper gastrointestinal resectional surgery.
Paisley, A. M., Madhavan, K. K., Paterson-Brown, S., Praseedom, R. K., Garden, O. J.
The 'New Deal' set out by the Department of Health in 1991, together with the introduction of specialist 6-year training grades by Calman in 1993, has resulted in a decrease in available training...
Staging laparoscopy for cholangiocarcinoma
Joseph, S., Connor, S., Garden, O. J.
The precise role of laparoscopic assessment of biliary tract malignancy is yet to be defined. The evidence for its use has been reviewed to establish the role of laparoscopy for preoperative staging...
Clark, E. J., Taylor, M. A., Connor, S., O'Neill, R., Brennan, M. F., Garden, O. J., ...
Introduction. Survival following resection for pancreatic ductal adenocarcinoma (PDAC) remains poor. The aim of this study was to validate a survival nomogram designed at the Memorial Sloan-Kettering...
Guidelines for resection of colorectal cancer liver metastases
Garden, O J, Rees, M, Poston, G J, Mirza, D, Saunders, M, Ledermann, J, ...
Thomson, B N J, Parks, R W, Redhead, D N, Welsh, F K S, Madhavan, K K, Wigmore, S J, ...
Laparoscopy and laparoscopic ultrasound have been validated previously as staging tools for pancreatic cancer. The aim of this study was to identify if assessment of vascular involvement with...
Simmonds, P C, Primrose, J N, Colquitt, J L, Garden, O J, Poston, G J, Rees, M
No consensus on the indications for surgical resection of colorectal liver metastases exists. This systematic review has been undertaken to assess the published evidence for its efficacy and safety...