Dunham, SP, Bruce, J, Klein, D, Flynn, JN, Golder, MC, MacDonald, S, ...
Limited efficacy of an inactivated feline immunodeficiency virus vaccine (2006)
Dunham, SP, Bruce, J, MacKay, S, Golder, M, Jarrett, O, Neil, JC
Ryan, G, Grimes, T, Brankin, B, Mabruk, MJEMF, Hosie, MJ, Jarrett, O, ...
Jarrett, O., Stow, J. L., Yap, A. S., Key, B.
Cadherin cell-cell adhesion molecules are important determinants of morphogenesis and tissue patterning. C-cadherin plays a key role in the cell-upon-cell movements seen during Xenopus gastrulation....
Hosie, M.J., Willett, B.J., Klein, D., Dunsford, T.H., Cannon, C., Shimojima, M., ...
The development of an effective vaccine against human immunodeficiency virus is considered to be the most practicable means of controlling the advancing global AIDS epidemic. Studies with the...
Jarrett, O., Stow, J. L., Yap, A. S., Key, B.
Cadherin cell-cell adhesion molecules are important determinants of morphogenesis and tissue patterning. C-cadherin plays a key role in the cell-upon-cell movements seen during Xenopus gastrulation....
Jarrett, O., Stow, J. L., Yap, A. S., Key, B.
Cadherin cell-cell adhesion molecules are important determinants of morphogenesis and tissue patterning. C-cadherin plays a key role in the cell-upon-cell movements seen during Xenopus gastrulation....
Jarrett, O., Stow, J. L., Yap, A. S., Key, B.
Cadherin cell-cell adhesion molecules are important determinants of morphogenesis and tissue patterning. C-cadherin plays a key role in the cell-upon-cell movements seen during Xenopus gastrulation....
The pattern of shedding of feline coronavirus (FCoV) was established in 155 naturally infected pet cats from 29 households over periods of up to five years. Viral RNA was detected in faeces by...
Hanlon, L, Argyle, D, Bain, D, Nicolson, L, Dunham, S, Golder, MC, ...
Prevalence of bovine immunodeficiency virus infection in cattle in Great Britain (2001)
Scobie, L, Venables, C, Sayers, AR, Weightman, S, Jarrett, O
Hosie, M. J., Dunsford, T., Klein, D., Willett, B.J., Cannon, C., Osbourne, R., ...
It has been shown that cats can be protected against infection with the prototypic Petaluma strain of feline immunodeficiency virus (FIVPET) using vaccines based on either inactivated virus particles...
Hosie, M.J., Flynn, J.N., Rigby, M.A., Cannon, C., Dunsford, T., Mackay, N.A., ...
To test the potential of a multigene DNA vaccine against lentivirus infection, we generated a defective mutant provirus of feline immunodeficiency virus (FIV) with an in-frame deletion in pol...
McDonald, M., Willett, B.J., Jarrett, O., Addie, D.D.
Chlamydia psittaci is a significant cause of conjunctivitis in cats, but can be difficult to diagnose owing to the small number of organisms in conjunctival swabs. In the United Kingdom laboratory...
Comparative efficiency of feline immunodeficiency virus infection by DNA inoculation (1997)
Rigby, M.A., Hosie, M.J., Willett, B.J., Mackay, N., McDonald, M., Cannon, C., ...
Direct inoculation of genetic material in DNA form is a novel approach to vaccination that has proved efficacious for a number of viral agents. We are interested in the potential of this approach for...
Beatty, J.A., Willett, B.J., Gault, E.A., Jarrett, O.
The evolution of the virus-specific cytotoxic T-lymphocyte response in two cats experimentally infected with feline immunodeficiency virus (FIV) was monitored. Effector cells were derived from...
Callanan, J.J., Jones, B.A., Irvine, J., Willett, B.J., McCandlish, I.A.P., Jarrett, O.
Lymphosarcoma (malignant lymphoma) is the commonest hematopoietic tumor in the cat. Many cases are associated with feline leukemia virus (FeLV) infection, but epidemiologic and experimental data...
Suppression of virus burden by immunization with feline immunodeficiency virus Env protein (1996)
Hosie, M.J., Dunsford, T.H., De Ronde, A., Willett, B.J., Cannon, C.A., Neil, J.C., ...
Whole inactivated virus (WIV) vaccines derived from the FLA cell line protect cats against challenge with feline immunodeficiency virus (FIV). To discover whether the protective effects of WIV could...
Hosie, M.J., Osborne, R., Yamamoto, J.K., Neil, J.C., Jarrett, O.
Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8)...
Location of B cell epitopes on the core protein p24 of feline immunodeficency virus. (1995)
Weijer, K., Langedijk, H., Herwijnen, R. Van, Pfauth, A., Siebelink, K., ...
Hosie, M.J., Willett, B.J., Dunsford, T.H., Jarrett, O., Neil, J.C.
Monoclonal antibody vpg15 detects a 24-kDa cell surface protein on feline cells permissive for infection with feline immunodeficiency virus (FIV). The antibody blocks infection of FIV-susceptible...
Weijer, K., Pfauth, A., Herwijnen, R. Van, Jarrett, O., Meloen, R.H., Tomee, C., ...
The surface glycoprotein, gp70, of feline leukaemia virus (FeLV) contains sites which are important in inducing neutralizing antibodies. Using synthetic peptides corresponding to nucleotide sequence...
Hosie, M.J., Robertson, C., Jarrett, O.
A representative sample of the pet cat population of the United Kingdom was surveyed. Blood samples from 1204 sick and 1007 healthy cats of known breed, age and sex were tested for antibodies to...
Serological responses in cats vaccinated with FeLV ISCOM and an inactivated FeLV vaccine. (1989)
Weijer, K., UytdeHaag, F., Knell, P., Jarrett, O., Morein, B.
Various approaches have been considered for generation of effective and safe vaccines against retroviruses, including HIV, with limited success. In the present vaccination study, encompassing 137...
Weijer, K., Jarrett, O., Lutz, H.
We have attempted to protect kittens against oronasal infection with FeLV (strain A/Glasgow-1) by treatment with a mixture of two virus-neutralizing (VN) MAbs (IgGl, K) directed against the same...
Weijer, K., UytdeHaag, F., Jarrett, O., Sundquist, B., Morein, B.
An effective candidate subunit vaccine consisting of the gp 70/85 of feline leukemia virus (FeLV) was prepared by using the immunostimulating complex (iscom) method for the presentation of membrane...
Hosie, M.J., Willett, B.J., Klein, D., Dunsford, T.H., Cannon, C., Shimojima, M., ...
The development of an effective vaccine against human immunodeficiency virus is considered to be the most practicable means of controlling the advancing global AIDS epidemic. Studies with the...
Ramsey, I. K., Spibey, N., Jarrett, O.
The external surface glycoprotein (SU) of feline leukemia virus (FeLV) contains sites which define the viral subgroup and induce virus-neutralizing antibodies. The subgroup phenotypic determinants...
Ryan, G., Klein, D., Knapp, E., Hosie, M. J., Grimes, T., ...
Animal models of human immunodeficiency virus 1, such as feline immunodeficiency virus (FIV), provide the opportunities to dissect the mechanisms of early interactions of the virus with the central...
Hosie, M J, Osborne, R, Yamamoto, J K, Neil, J C, Jarrett, O
Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8)...
Beatty, J A, Willett, B J, Gault, E A, Jarrett, O
The evolution of the virus-specific cytotoxic T-lymphocyte response in two cats experimentally infected with feline immunodeficiency virus (FIV) was monitored. Effector cells were derived from...
Flynn, J N, Cannon, C A, Neil, J C, Jarrett, O
Cats were immunized with a 46-residue multiepitopic synthetic peptide of feline immunodeficiency virus (FIV) comprising immunodominant epitopes present in the third variable domain of the envelope...
Hosie, M J, Willett, B J, Dunsford, T H, Jarrett, O, Neil, J C
Monoclonal antibody vpg15 detects a 24-kDa cell surface protein on feline cells permissive for infection with feline immunodeficiency virus (FIV). The antibody blocks infection of FIV-susceptible...
Tartaglia, J, Jarrett, O, Neil, J C, Desmettre, P, Paoletti, E
Two ALVAC (canarypox virus)-based recombinant viruses expressing the feline leukemia virus (FeLV) subgroup A env and gag genes were assessed for their protective efficacy in cats. Both recombinant...
Detection of feline leukemia virus infection in saliva.
The question was investigated whether feline leukemia virus (FeLV) infection may be diagnosed by testing saliva in an enzyme-linked immunosorbent assay (ELISA). Saliva was collected with commercially...
Hosie, M. J., Dunsford, T., Klein, D., Willett, B.J., Cannon, C., Osbourne, R., ...
It has been shown that cats can be protected against infection with the prototypic Petaluma strain of feline immunodeficiency virus (FIVPET) using vaccines based on either inactivated virus particles...
Hosie, M.J., Flynn, J.N., Rigby, M.A., Cannon, C., Dunsford, T., Mackay, N.A., ...
To test the potential of a multigene DNA vaccine against lentivirus infection, we generated a defective mutant provirus of feline immunodeficiency virus (FIV) with an in-frame deletion in pol...
Beatty, J.A., Willett, B.J., Gault, E.A., Jarrett, O.
The evolution of the virus-specific cytotoxic T-lymphocyte response in two cats experimentally infected with feline immunodeficiency virus (FIV) was monitored. Effector cells were derived from...
Hosie, M.J., Osborne, R., Yamamoto, J.K., Neil, J.C., Jarrett, O.
Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8)...
Hosie, M.J., Willett, B.J., Dunsford, T.H., Jarrett, O., Neil, J.C.
Monoclonal antibody vpg15 detects a 24-kDa cell surface protein on feline cells permissive for infection with feline immunodeficiency virus (FIV). The antibody blocks infection of FIV-susceptible...
Ramsey, I. K., Spibey, N., Jarrett, O.
The external surface glycoprotein (SU) of feline leukemia virus (FeLV) contains sites which define the viral subgroup and induce virus-neutralizing antibodies. The subgroup phenotypic determinants...
Ryan, G., Klein, D., Knapp, E., Hosie, M. J., Grimes, T., ...
Animal models of human immunodeficiency virus 1, such as feline immunodeficiency virus (FIV), provide the opportunities to dissect the mechanisms of early interactions of the virus with the central...
Hosie, M J, Osborne, R, Yamamoto, J K, Neil, J C, Jarrett, O
Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8)...
Beatty, J A, Willett, B J, Gault, E A, Jarrett, O
The evolution of the virus-specific cytotoxic T-lymphocyte response in two cats experimentally infected with feline immunodeficiency virus (FIV) was monitored. Effector cells were derived from...
Flynn, J N, Cannon, C A, Neil, J C, Jarrett, O
Cats were immunized with a 46-residue multiepitopic synthetic peptide of feline immunodeficiency virus (FIV) comprising immunodominant epitopes present in the third variable domain of the envelope...
Hosie, M J, Willett, B J, Dunsford, T H, Jarrett, O, Neil, J C
Monoclonal antibody vpg15 detects a 24-kDa cell surface protein on feline cells permissive for infection with feline immunodeficiency virus (FIV). The antibody blocks infection of FIV-susceptible...
Tartaglia, J, Jarrett, O, Neil, J C, Desmettre, P, Paoletti, E
Two ALVAC (canarypox virus)-based recombinant viruses expressing the feline leukemia virus (FeLV) subgroup A env and gag genes were assessed for their protective efficacy in cats. Both recombinant...
Detection of feline leukemia virus infection in saliva.
The question was investigated whether feline leukemia virus (FeLV) infection may be diagnosed by testing saliva in an enzyme-linked immunosorbent assay (ELISA). Saliva was collected with commercially...
Cytokine production by cats infected with feline immunodeficiency virus: a longitudinal study.
Lawrence, C E, Callanan, J J, Willett, B J, Jarrett, O
The immune responsiveness of cats naturally or experimentally infected with feline immunodeficiency virus (FIV) was studied. Peripheral blood mononuclear cells (PBMC) from naturally infected,...
Flynn, J N, Cannon, C A, Reid, G, Rigby, M A, Neil, J C, Jarrett, O
Cytotoxic T-cell determinants should be an important component of a vaccine against feline immunodeficiency virus (FIV). Epitope mapping studies have revealed an immunodominant neutralization epitope...
Mowat, A M, Donachie, A M, Reid, G, Jarrett, O
Induction of all forms of protective immunity by oral immunization with subunit vaccines is an ideal goal for the development of novel vaccines, but creates several theoretical problems from the...
Willett, B J, Hosie, M J, Callanan, J J, Neil, J C, Jarrett, O
Lymphocyte subset analysis was performed on specific pathogen-free cats infected with feline immunodeficiency virus (FIV). As early as 4 weeks post-infection a sharp rise in lymphocytes expressing...
Willett, B J, Hosie, M J, Jarrett, O, Neil, J C
A monoclonal antibody vpg15 has been identified which recognizes a putative cellular receptor for feline immunodeficiency virus (FIV). The antibody immunoprecipitates a single 24,000 MW species from...
Polyclonal B-cell activation in cats infected with feline immunodeficiency virus.
Flynn, J N, Cannon, C A, Lawrence, C E, Jarrett, O
The specificity of the antibody response following natural or experimental infection of domestic cats with feline immunodeficiency virus (FIV) was examined. The antibody response to a range of...
Hosie, M.J., Willett, B.J., Klein, D., Dunsford, T.H., Cannon, C., Shimojima, M., ...
The development of an effective vaccine against human immunodeficiency virus is considered to be the most practicable means of controlling the advancing global AIDS epidemic. Studies with the...
Hosie, M. J., Dunsford, T., Klein, D., Willett, B.J., Cannon, C., Osbourne, R., ...
It has been shown that cats can be protected against infection with the prototypic Petaluma strain of feline immunodeficiency virus (FIVPET) using vaccines based on either inactivated virus particles...
Hosie, M.J., Flynn, J.N., Rigby, M.A., Cannon, C., Dunsford, T., Mackay, N.A., ...
To test the potential of a multigene DNA vaccine against lentivirus infection, we generated a defective mutant provirus of feline immunodeficiency virus (FIV) with an in-frame deletion in pol...
Beatty, J.A., Willett, B.J., Gault, E.A., Jarrett, O.
The evolution of the virus-specific cytotoxic T-lymphocyte response in two cats experimentally infected with feline immunodeficiency virus (FIV) was monitored. Effector cells were derived from...
Hosie, M.J., Osborne, R., Yamamoto, J.K., Neil, J.C., Jarrett, O.
Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8)...
Hosie, M.J., Willett, B.J., Dunsford, T.H., Jarrett, O., Neil, J.C.
Monoclonal antibody vpg15 detects a 24-kDa cell surface protein on feline cells permissive for infection with feline immunodeficiency virus (FIV). The antibody blocks infection of FIV-susceptible...
Jarrett, O, Stow, JL, Yap, AS, Key, B
Cadherin cell-cell adhesion molecules are important determinants of morphogenesis and tissue patterning. C-cadherin plays a key role in the cell-upon-cell movements seen during Xenopus gastrulation....
Flynn, J N, Cannon, C A, Sloan, D, Neil, J C, Jarrett, O
Mitogen-activated lymphoblasts isolated from the blood and lymph nodes, but not the spleen, of domestic cats acutely infected with the Petaluma or Glasgow8 isolates of feline immunodeficiency virus...
Feline leukaemia virus: protective immunity is mediated by virus-specific cytotoxic T lymphocytes
Flynn, J N, Hanlon, L, Jarrett, O
Feline leukaemia virus (FeLV) nucleic acid vaccination of domestic cats affords protection against viraemia and the development of latency without inducing antiviral antibodies.1 To determine the...