Noranate, Nitchakarn, Prugnolle, Franck, Jouin, Hélène, Tall, Adama, Marrama, Laurence, Sokhna, Cheikh, ...
Abstract Background Genetic evidence for diversifying selection identified the Merozoite Surface Protein1 block2 (PfMSP1 block2) as a putative target of protective immunity against Plasmodium...
Steenkeste, Nicolas, Dillies, Marie-Agnès, Khim, Nimol, Sismeiro, Odile, Chy, Sophy, Lim, Pharath, ...
Abstract Background A number of molecular tools have been developed to monitor the emergence and spread of anti-malarial drug resistance to Plasmodium falciparum . One of the major obstacles to the...
Steenkeste, Nicolas, Incardona, Sandra, Chy, Sophy, Duval, Linda, Ekala, Marie-Thérèse, Lim, Pharath, ...
Abstract Background Several strategies are currently deployed in many countries in the tropics to strengthen malaria control toward malaria elimination. To measure the impact of any intervention,...
Natalang, Onguma, Bischoff, Emmanuel, Deplaine, Guillaume, Proux, Caroline, Dillies, Marie-Agnès, Sismeiro, Odile, ...
Abstract Background Translation of the genome sequence of Plasmodium sp . into biologically relevant information relies on high through-put genomics technology which includes transcriptome analysis....
Ayouba, Ahidjo, Badaut, Cyril, Kfutwah, Anfumbom, Cannou, Claude, Juillerat, Alexandre, Gangnard, Stéphane, ...
No abstract available.
Niang, Makhtar, Marrama, Laurence, Ekala, Marie Therese, Alioune, Gaye, Tall, Adama, Ndiaye, Jean L., ...
Objectives Chemoprophylaxis is recommended during pregnancy to reduce the risk of placental infection. However, in areas with increasing drug resistance, it can trigger selection of resistant...
Sequence analysis of Plasmodium falciparumcytochrome b in multiple geographic sites (2007)
Ekala, Marie-Thérèse, Khim, Nimol, Legrand, Eric, Randrianarivelojosia, Milijaona, Jambou, Ronan, Fandeur, Thierry, ...
Abstract Background The antimalarial drug atovaquone specifically targets Plasmodium falciparum cytochrome b ( Pfcytb ), a mitochondrial gene with uniparental inheritance. Cases of resistance to...
Eisen, Damon P, Wang, Lina, Jouin, Helene, Murhandarwati, E Elsa H, Black, Casilda G, Mercereau-Puijalon, Odile, ...
Abstract Background Asexual stage antibody responses following initial Plasmodium falciparum infections in previously healthy adults may inform vaccine development, yet these have not been as...
Incardona, Sandra, Vong, Sirenda, Chiv, Lim, Lim, Pharath, Nhem, Sina, Sem, Rithy, ...
Abstract Background In Cambodia, estimates of the malaria burden rely on a public health information system that does not record cases occurring among remote populations, neither malaria cases...
Incardona, Sandra, Vong, Sirenda, Chiv, Lim, Lim, Pharath, Nhem, Sina, Sem, Rithy, ...
Abstract Background In Cambodia, estimates of the malaria burden rely on a public health information system that does not record cases occurring among remote populations, neither malaria cases...
Invasion of Africa by a single pfcrtallele of South East Asian type (2006)
Ariey, Frédéric, Fandeur, Thierry, Durand, Remy, Randrianarivelojosia, Milijaona, Jambou, Ronan, Legrand, Eric, ...
Abstract Background Because of its dramatic public health impact, Plasmodium falciparum resistance to chloroquine (CQ) has been documented early on. Chloroquine-resistance (CQR) emerged in the late...
Legrand, Eric, Volney, Beatrice, Lavergne, Anne, Tournegros, Caroline, Florent, Loïc, Accrombessi, Doris, ...
Abstract Background Plasmodium falciparum outbreaks can occur in the coastal area of French Guiana, where the population is essentially non-immune. Two sporadic outbreaks were observed, including one...
Schneider, Achim G, Mercereau-Puijalon, Odile
Abstract Background Malaria caused by protozoan parasites of the genus Plasmodium spp . is a major health burden in tropical countries. The development of new control tools, including vaccines and...
Boeuf, Philippe, Vigan-Womas, Inès, Jublot, Delphine, Loizon, Séverine, Barale, Jean-Christophe, Akanmori, Bartholomew, ...
Abstract Background Real-time PCR is becoming a common tool for detecting and quantifying expression profiling of selected genes. Cytokines mRNA quantification is widely used in immunological...
Boeuf, Philippe, Vigan-Womas, Inès, Jublot, Delphine, Loizon, Séverine, Barale, Jean-Christophe, Akanmori, Bartholomew Dicky, ...
BACKGROUND: Real-time PCR is becoming a common tool for detecting and quantifying expression profiling of selected genes. Cytokines mRNA quantification is widely used in immunological research to...
Boeuf, Philippe, Vigan-Womas, Inès, Jublot, Delphine, Loizon, Séverine, Barale, Jean-Christophe, Akanmori, Bartholomew Dicky, ...
BACKGROUND: Real-time PCR is becoming a common tool for detecting and quantifying expression profiling of selected genes. Cytokines mRNA quantification is widely used in immunological research to...
Hviid, Lars, Akanmori, Bartholomew D., Loizon, Severine, Kurtzhals, Jorgen A. L., Ricke, Christina H., Lim, Annick, ...
TCR γδ+ cells constitute
Langsley, Gordon, Sibilli, Lise, Mattei, Denise, Falanga, Pierre, Mercereau-Puijalon, Odile
The molecular karyotypes of P.chabaudi and P.falciparum have been compared by pulse field gradient e 1 ectrophores 1s . P.chabaudi has 3 extra chromosomes in the 750 – 2000 Kb range although the...
Langsley, Gordon, Scherf, Artur, Mercereau-Puijalon, Odile, Koenen, Michael, Kahane, Bernard, Mattei, Denise, ...
A genomic expression library of P.falciparum has been differentially screened with a number of immune sera. The response of 9 clones to the various sera is presented, together with the DNA sequence...
Mahieux, Renaud, Horal, Peter, Mauclère, Philippe, Mercereau-Puijalon, Odile, Guillotte, Micheline, Meertens, Laurent, ...
To gain insight on the significance of human T-cell lymphotropic virus type 1 (HTLV-1) indeterminate serological reactivities, we studied villagers of South Cameroon, focusing on a frequent and...
Le Scanf, Cécile, Fandeur, Thierry, Bonnefoy, Serge, Guillotte, Micheline, Mercereau-Puijalon, Odile
A primary infection by the Plasmodium falciparum Palo Alto O and R antigenic variants induces a variant-specific immunity in the Saimiri sciureus monkey. We have shown that these variants express...
Hviid, Lars, Kurtzhals, Jørgen A. L., Adabayeri, Victoria, Loizon, Severine, Kemp, Kåre, Goka, Bamenla Q., ...
γδ T cells have variously been implicated in the protection against, and the pathogenesis of, malaria, but few studies have examined the γδ T-cell response to malaria in African children, who...
Garraud, Olivier, Perraut, Ronald, Diouf, Ababacar, Nambei, Wilfrid S., Tall, Adama, Spiegel, André, ...
Cytophilic antibodies (Abs) play a critical role in protection against Plasmodium falciparum blood stages, yet little is known about the parameters regulating production of these Abs. We used an in...
Diatta, Antoine-Marie, Marrama, Laurence, Tall, Adama, Trape, Jean-François, Dieye, Alioune, Garraud, Olivier, ...
To investigate the potential for use of a well-established strain of Plasmodium falciparum as a reference strain for infected red blood cell (IRBC) surface reactivity, we monitored the binding of...
Boeuf, Philippe, Vigan-Womas, Inès, Jublot, Delphine, Loizon, Séverine, Barale, Jean-Christophe, Akanmori, Bartholomew Dicky, ...
Legrand, Eric, Volney, Beatrice, Lavergne, Anne, Tournegros, Caroline, Florent, Loïc, Accrombessi, Doris, ...
Invasion of Africa by a single pfcrt allele of South East Asian type
Ariey, Frédéric, Fandeur, Thierry, Durand, Remy, Randrianarivelojosia, Milijaona, Jambou, Ronan, Legrand, Eric, ...
Mahieux, Renaud, Horal, Peter, Mauclère, Philippe, Mercereau-Puijalon, Odile, Guillotte, Micheline, Meertens, Laurent, ...
To gain insight on the significance of human T-cell lymphotropic virus type 1 (HTLV-1) indeterminate serological reactivities, we studied villagers of South Cameroon, focusing on a frequent and...
Le Scanf, Cécile, Fandeur, Thierry, Bonnefoy, Serge, Guillotte, Micheline, Mercereau-Puijalon, Odile
A primary infection by the Plasmodium falciparum Palo Alto O and R antigenic variants induces a variant-specific immunity in the Saimiri sciureus monkey. We have shown that these variants express...
Hviid, Lars, Kurtzhals, Jørgen A. L., Adabayeri, Victoria, Loizon, Severine, Kemp, Kåre, Goka, Bamenla Q., ...
γδ T cells have variously been implicated in the protection against, and the pathogenesis of, malaria, but few studies have examined the γδ T-cell response to malaria in African children, who...
Garraud, Olivier, Perraut, Ronald, Diouf, Ababacar, Nambei, Wilfrid S., Tall, Adama, Spiegel, André, ...
Cytophilic antibodies (Abs) play a critical role in protection against Plasmodium falciparum blood stages, yet little is known about the parameters regulating production of these Abs. We used an in...
Diatta, Antoine-Marie, Marrama, Laurence, Tall, Adama, Trape, Jean-François, Dieye, Alioune, Garraud, Olivier, ...
To investigate the potential for use of a well-established strain of Plasmodium falciparum as a reference strain for infected red blood cell (IRBC) surface reactivity, we monitored the binding of...
Boeuf, Philippe, Vigan-Womas, Inès, Jublot, Delphine, Loizon, Séverine, Barale, Jean-Christophe, Akanmori, Bartholomew Dicky, ...
Legrand, Eric, Volney, Beatrice, Lavergne, Anne, Tournegros, Caroline, Florent, Loïc, Accrombessi, Doris, ...
Invasion of Africa by a single pfcrt allele of South East Asian type
Ariey, Frédéric, Fandeur, Thierry, Durand, Remy, Randrianarivelojosia, Milijaona, Jambou, Ronan, Legrand, Eric, ...
Noranate, Nitchakarn, Durand, Rémy, Tall, Adama, Marrama, Laurence, Spiegel, André, Sokhna, Cheikh, ...
Large-scale malaria survey in Cambodia: Novel insights on species distribution and risk factors
Incardona, Sandra, Vong, Sirenda, Chiv, Lim, Lim, Pharath, Nhem, Sina, Sem, Rithy, ...
Moll, Kirsten, Pettersson, Fredrik, Vogt, Anna M., Jonsson, Cathrine, Rasti, Niloofar, Ahuja, Sanjay, ...
The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is an important virulence factor on the surface of infected erythrocytes. Naturally acquired antibodies to PfEMP1 expressed by...
Eisen, Damon P, Wang, Lina, Jouin, Helene, Murhandarwati, E Elsa H, Black, Casilda G, Mercereau-Puijalon, Odile, ...
Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites
Ekala, Marie-Thérèse, Khim, Nimol, Legrand, Eric, Randrianarivelojosia, Milijaona, Jambou, Ronan, Fandeur, Thierry, ...
Genetic Determination and Linkage Mapping of Plasmodium falciparum Malaria Related Traits in Senegal
Sakuntabhai, Anavaj, Ndiaye, Rokhaya, Casadémont, Isabelle, Peerapittayamonkol, Chayanon, Rogier, Christophe, Tortevoye, Patricia, ...
Plasmodium falciparum malaria episodes may vary considerably in their severity and clinical manifestations. There is good evidence that host genetic factors contribute to this variability. To date,...
Legrand, Eric, Volney, Béatrice, Meynard, Jean-Baptiste, Mercereau-Puijalon, Odile, Esterre, Philippe
Implemented as one arm of the malaria control program in French Guiana in the early 1990s, our laboratory has since established in vitro profiles for parasite drug susceptibility to a panel of eight...
Natalang, Onguma, Bischoff, Emmanuel, Deplaine, Guillaume, Proux, Caroline, Dillies, Marie-Agnès, Sismeiro, Odile, ...
Sakuntabhai, Anavaj, Ndiaye, Rokhaya, Casadémont, Isabelle, Peerapittayamongkol, Chayanon, Rogier, Christophe, Tortevoye, Patricia, ...
Re-evaluation of how artemisinins work in light of emerging evidence of in vitro resistance
Krishna, Sanjeev, Woodrow, Charles J., Staines, Henry M., Haynes, Richard K., Mercereau-Puijalon, Odile
There are more than half a billion cases of malaria every year. Combinations of an artemisinin with other antimalarial drugs are now recommended treatments for Plasmodium falciparum malaria in most...
Towards high-throughput molecular detection of Plasmodium: new approaches and molecular markers
Steenkeste, Nicolas, Incardona, Sandra, Chy, Sophy, Duval, Linda, Ekala, Marie-Thérèse, Lim, Pharath, ...
Vigan-Womas, Inès, Guillotte, Micheline, Le Scanf, Cécile, Igonet, Sébastien, Petres, Stéphane, Juillerat, Alexandre, ...
In the Saimiri sciureus monkey, erythrocytes infected with the varO antigenic variant of the Plasmodium falciparum Palo Alto 89F5 clone bind uninfected red blood cells (rosetting), form...
Vigan-Womas, Inès, Guillotte, Micheline, Le Scanf, Cécile, Igonet, Sébastien, Petres, Stéphane, Juillerat, Alexandre, ...
Resistance to Dihydroartemisinin
Legrand, Eric, Volney, Beatrice, Meynard, Jean-Baptiste, Esterre, Philippe, Mercereau-Puijalon, Odile