Odile Thoison

Molecular Determinant of Regioselective Hydroxylation of Docetaxel by CYP3A4 (2009)

Bernard Monsarrat, Odile Thoison, Joelle Dubois, Thierry Cresteil

The metabolism of taxanes by human liver microsomes is regioselective: the major metabolite of paclitaxel formed by CYP2C8 results from the hydroxylation on the taxane ring at C-6. Hydroxylations on...

Insect antifeedant compounds from Nothofagus dombeyi and N-pumilio (2004)

Thoison, Odile, Sévenet, Thierry, Niemeyer, Hermann, Russell, Graeme B.

A bioassay-guided purification of the extracts of Nothofagus dombeyi and N. pumilio leaves yielded several triterpenes and flavonoids including 2-O-acetylmaslinic acid, 3-O-acetyl...