Ohene Adjei

Onchocerciasis Control: Vision for the Future from a Ghanian perspective (2009)

Taylor, Mark J, Awadzi, Kwablah, Basáñez, María-Gloria, Biritwum, Nana, Boakye, Daniel, Boatin, Boakye, ...

Abstract Since 1987 onchocerciasis control has relied on the donation of ivermectin (Mectizan ® , Merck & Co., Inc.) through the Mectizan Donation Programme. Recently, concern has been raised over...

Sickle cell trait (HbAS) and stunting in children below two years of age in an area of high malaria transmission (2009)

Kreuels, Benno, Ehrhardt, Stephan, Kreuzberg, Christina, Adjei, Samuel, Kobbe, Robin, Burchard, Gerd D, ...

Abstract Background While the protective effects of sickle cell trait (HbAS) against severe malaria and the resulting survival advantage are well known, the impact on the physical development in...

Therapeutic and prophylactic effect of intermittent preventive anti-malarial treatment in infants (IPTi) from Ghana and Gabon (2008)

May, Jürgen, Adjei, Samuel, Busch, Wibke, Gabor, Julian J, Issifou, Saadou, Kobbe, Robin, ...

Abstract Background Intermittent preventive treatment in infants (IPTi) with sulphadoxine-pyrimethamine (SP) reduces the incidence of malaria episodes in young children. The exact mechanism by which...

Malaria incidence and efficacy of intermittent preventive treatment in infants (IPTi) (2007)

Kobbe, Robin, Adjei, Samuel, Kreuzberg, Christina, Kreuels, Benno, Thompson, Benedicta, Thompson, Peter A, ...

Abstract Background Intermittent preventive antimalarial treatment in infants (IPTi) is currently evaluated as a malaria control strategy. Among the factors influencing the extent of protection that...

For information about other BioMed Central publications go to (2007)

Robin Kobbe, Samuel Adjei, Christina Kreuzberg, Benno Kreuels, Benedicta Thompson, Peter A Thompson, ...

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Doxycycline Reduces Plasma VEGF-C/sVEGFR-3 and Improves Pathology in Lymphatic Filariasis (2006)

Alexander Yaw Debrah, Sabine Mand, Sabine Specht, Yeboah Marfo-Debrekyei, Linda Batsa, Kenneth Pfarr, ...

Lymphatic filariasis is a disease of considerable socioeconomic burden in the tropics. Presently used antifilarial drugs are able to strongly reduce transmission and will thus ultimately lower the...

Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin (2006)

Debrah, Alexander, Mand, Sabine, Marfo-Debrekyei, Yeboah, Larbi, John, Adjei, Ohene, Hoerauf, Achim

Abstract Background Infection with the filarial nematode Onchocerca volvulus can lead to severe dermatitis, visual impairment, and ultimately blindness. Since the currently used drug, ivermectin does...

Frequent detection of worm movements in onchocercal nodules by ultrasonography (2005)

Mand, Sabine, Marfo-Debrekyei, Yeboah, Debrah, Alex, Buettner, Marcelle, Batsa, Linda, Pfarr, Kenneth, ...

Abstract Background Ultrasonography (USG) is known to be a suitable tool for diagnosis in lymphatic filariasis as the adult filarial nematode Wuchereria bancrofti in scrotal lymphatic vessels of...

Animated documentation of the filaria dance sign (FDS) in bancroftian filariasis (2003)

Mand, Sabine, Marfo-Debrekyei, Yeboah, Dittrich, Matthias, Fischer, Kerstin, Adjei, Ohene, Hoerauf, Achim

Abstract Background Ultrasonography is able to detect adult Wuchereria bancrofti worms in scrotal lymphatic vessels of infected men on account of the characteristic pattern of adult worm movements,...

Doxycycline Reduces Plasma VEGF-C/sVEGFR-3 and Improves Pathology in Lymphatic Filariasis

Debrah, Alexander Yaw, Mand, Sabine, Specht, Sabine, Marfo-Debrekyei, Yeboah, Batsa, Linda, Pfarr, Kenneth, ...

Lymphatic filariasis is a disease of considerable socioeconomic burden in the tropics. Presently used antifilarial drugs are able to strongly reduce transmission and will thus ultimately lower the...

Doxycycline Reduces Plasma VEGF-C/sVEGFR-3 and Improves Pathology in Lymphatic Filariasis

Debrah, Alexander Yaw, Mand, Sabine, Specht, Sabine, Marfo-Debrekyei, Yeboah, Batsa, Linda, Pfarr, Kenneth, ...

Lymphatic filariasis is a disease of considerable socioeconomic burden in the tropics. Presently used antifilarial drugs are able to strongly reduce transmission and will thus ultimately lower the...

Of Mice, Cattle, and Humans: The Immunology and Treatment of River Blindness

Allen, Judith E., Adjei, Ohene, Bain, Odile, Hoerauf, Achim, Hoffmann, Wolfgang H., Makepeace, Benjamin L., ...

River blindness is a seriously debilitating disease caused by the filarial parasite Onchocerca volvulus, which infects millions in Africa as well as in South and Central America. Research has been...

Onchocerciasis Control: Vision for the Future from a Ghanian perspective

Taylor, Mark J, Awadzi, Kwablah, Basáñez, María-Gloria, Biritwum, Nana, Boakye, Daniel, Boatin, Boakye, ...

Since 1987 onchocerciasis control has relied on the donation of ivermectin (Mectizan®, Merck & Co., Inc.) through the Mectizan Donation Programme. Recently, concern has been raised over the...

Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study

Hoerauf, Achim, Specht, Sabine, Büttner, Marcelle, Pfarr, Kenneth, Mand, Sabine, Fimmers, Rolf, ...

In a randomized, placebo-controlled trial in Ghana, 67 onchocerciasis patients received 200-mg/day doxycycline for 4–6 weeks, followed by ivermectin (IVM) after 6 months. After 6–27 months,...

Mycobacterium ulcerans disease.

Van Der Werf, Tjip S., Stienstra, Ymkje, Johnson, R. Christian, Phillips, Richard, Adjei, Ohene, Fleischer, Bernhard, ...

Mycobacterium ulcerans disease (Buruli ulcer) is an important health problem in several west African countries. It is prevalent in scattered foci around the world, predominantly in riverine areas...

Newly acquired Onchocerca volvulus filariae after doxycycline treatment

Specht, Sabine, Hoerauf, Achim, Adjei, Ohene, Debrah, Alexander, Büttner, Dietrich W.

Despite successful mass drug administration and vector control programs, the nematode Onchocerca volvulus is far from being eradicated. Therefore, new long-term sterilizing or macrofilaricidal drugs...