Defective p53 response and apoptosis associated with an ataxia-telangiectasia-like phenotype (2006)
Gueven, N, Becherel, OJ, Birrell, G, Chen, P, DelSal, G, Carney, JP, ...
Ataxia-telangiectasia mutated (ATM), the protein defective in ataxia-telangiectasia, plays a central role in DNA damage response and signaling to cell cycle checkpoints. We describe here a cell line...
Becherel, OJ, Gueven, N, Birrell, GW, Schreiber, V, Suraweera, A, Jakob, B, ...
The APTX gene, mutated in patients with the neurological disorder ataxia with oculomotor apraxia type 1 (AOA1), encodes a novel protein aprataxin. We describe here, the interaction and...
Aprataxin, a novel protein that protects against genotoxic stress (2004)
Gueven, N, Becherel, OJ, Kijas, AW, Chen, P, Howe, O, Rudolph, JH, ...
Ataxia-oculomotor apraxia (AOA1) is a neurological disorder with symptoms that overlap those of ataxia-telangiectasia, a syndrome characterized by abnormal responses to double-strand DNA breaks and...