Ramsey, Chris, Winqvist, Ola, Puhakka, Lea, Halonen, Maria, Moro, Aune, Kämpe, Olle, ...
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a monogenic autosomal recessive disease caused by mutations in the AIRE gene. Here we have produced knock-out mice for the...
Intercellular adhesion molecule-1 inhibits interleukin 4 production by naive T cells
Luksch, Claudia R., Winqvist, Ola, Ozaki, Minette E., Karlsson, Lars, Jackson, Michael R., Peterson, Per A., ...
The type of cytokines produced during T cell responses determines susceptibility or resistance to many pathogens and influences the development of autoimmunity and allergy. To define the role of...
Intercellular adhesion molecule-1 inhibits interleukin 4 production by naive T cells
Luksch, Claudia R., Winqvist, Ola, Ozaki, Minette E., Karlsson, Lars, Jackson, Michael R., Peterson, Per A., ...
The type of cytokines produced during T cell responses determines susceptibility or resistance to many pathogens and influences the development of autoimmunity and allergy. To define the role of...
Kämäräinen, Meerit, Heiskala, Kukka, Knuutila, Sakari, Heiskala, Marja, Winqvist, Ola, Andersson, Leif C.
We screened expressed sequence tag databases for genes with up-regulated expression in inflammatory bowel diseases. A gene encoding a regenerating protein (REG)-like protein called RELP was...
FOXP3 Promoter Demethylation Reveals the Committed Treg Population in Humans
Janson, Peter C. J., Winerdal, Malin E., Marits, Per, Thörn, Magnus, Ohlsson, Rolf, Winqvist, Ola
Wermeling, Fredrik, Chen, Yunying, Pikkarainen, Timo, Scheynius, Annika, Winqvist, Ola, Izui, Shozo, ...
Apoptotic cells are considered to be a major source for autoantigens in autoimmune diseases such as systemic lupus erythematosus (SLE). In agreement with this, defective clearance of apoptotic cells...
Metinel Node—The First Lymph Node Draining a Metastasis—Contains Tumor-Reactive Lymphocytes
Dahl, Kjell, Karlsson, Mona, Marits, Per, Hoffstedt, Anna, Winqvist, Ola, Thörn, Magnus
AIRE regulates T-cell-independent B-cell responses through BAFF
Lindh, Emma, Lind, Sara M., Lindmark, Evelina, Hässler, Signe, Perheentupa, Jaakko, Peltonen, Leena, ...
Autoimmune polyendocrine syndrome type I (APS I) results in multiple endocrine organ destruction and is caused by mutations in the autoimmune regulator gene (AIRE). APS I is characterized by...
SOCS2 Influences LPS Induced Human Monocyte-Derived Dendritic Cell Maturation
Hu, Jin, Winqvist, Ola, Flores-Morales, Amilcar, Wikström, Ann-Charlotte, Norstedt, Gunnar
Dendritic cells (DCs) are highly specific antigen presenting cells, which link innate and adaptive immune responses and participate in protecting hosts from invading pathogens. DCs can be generated...