Olga M. Sinilnikova

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers (2009)

Antoniou, Antonis C., Sinilnikova, Olga M., McGuffog, Lesley, Healey, Sue, Nevanlinna, Heli, Heikkinen, Tuomas, ...

Genome-wide association studies of breast cancer have identified multiple single nucleotide polymorphisms (SNPs) that are associated with increased breast cancer risks in the general population. In a...

Acetyl-CoA carboxylase {alpha} gene and breast cancer susceptibility (2004)

Sinilnikova, Olga M., Ginolhac, Sophie M., Magnard, Clémence, Léoné, Mélanie, Anczukow, Olga, Hughes, David, ...

The identification of an interaction between BRCA1 and acetyl-CoA carboxylase α (ACCα), a key enzyme in lipid synthesis, led us to investigate the role of ACCα in breast cancer development, where...

Acetyl-CoA carboxylase {alpha} gene and breast cancer susceptibility (2004)

Sinilnikova, Olga M., Ginolhac, Sophie M., Magnard, Clémence, Léoné, Mélanie, Anczukow, Olga, Hughes, David, ...

The identification of an interaction between BRCA1 and acetyl-CoA carboxylase α (ACCα), a key enzyme in lipid synthesis, led us to investigate the role of ACCα in breast cancer development, where...

Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium (2002)

Thompson, Deborah, Szabo, Csilla I., Mangion, Jon, Oldenburg, Rogier A., Odefrey, Fabrice, Seal, Sheila, ...

The known susceptibility genes for breast cancer, including BRCA1 and BRCA2, only account for a minority of the familial aggregation of the disease. A recent study of 77 multiple case breast cancer...

Re: Pretest Prediction of BRCA1 or BRCA2 Mutation by Risk Counselors and the Computer Model BRCAPRO (2002)

Bonadona, Valerie, Sinilnikova, Olga M., Lenoir, Gilbert M., Lasset, Christine

The nonsense-mediated mRNA decay pathway triggers degradation of most BRCA1 mRNAs bearing premature termination codons (2002)

Perrin-Vidoz, Laure, Sinilnikova, Olga M., Stoppa-Lyonnet, Dominique, Lenoir, Gilbert M., Mazoyer, Sylvie

Germline mutations in the BRCA1 gene are scattered over the 22 coding exons and most of them generate premature termination codons (PTCs). A mechanism called nonsense-mediated mRNA decay (NMD) is...

Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium

Thompson, Deborah, Szabo, Csilla I., Mangion, Jon, Oldenburg, Rogier A., Odefrey, Fabrice, Seal, Sheila, ...

The known susceptibility genes for breast cancer, including BRCA1 and BRCA2, only account for a minority of the familial aggregation of the disease. A recent study of 77 multiple case breast cancer...

Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium

Thompson, Deborah, Szabo, Csilla I., Mangion, Jon, Oldenburg, Rogier A., Odefrey, Fabrice, Seal, Sheila, ...

The known susceptibility genes for breast cancer, including BRCA1 and BRCA2, only account for a minority of the familial aggregation of the disease. A recent study of 77 multiple case breast cancer...

Distinct BRCA1 Rearrangements Involving the BRCA1 Pseudogene Suggest the Existence of a Recombination Hot Spot

Puget, Nadine, Gad, Sophie, Perrin-Vidoz, Laure, Sinilnikova, Olga M., Stoppa-Lyonnet, Dominique, Lenoir, Gilbert M., ...

The 5′ end of the breast and ovarian cancer–susceptibility gene BRCA1 has previously been shown to lie within a duplicated region of chromosome band 17q21. The duplicated region contains BRCA1...

Common Breast Cancer-Predisposition Alleles Are Associated with Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Antoniou, Antonis C., Spurdle, Amanda B., Sinilnikova, Olga M., Healey, Sue, Pooley, Karen A., Schmutzler, Rita K., ...

Germline mutations in BRCA1 and BRCA2 confer high risks of breast cancer. However, evidence suggests that these risks are modified by other genetic or environmental factors that cluster in families....