Oliver Liesenfeld

Small intestinal inflammation following oral infection with Toxoplasmagondii   does not occur exclusively in C57BL/6 mice: review of 70 reports from the literature (2009)

Schreiner, Maximilian, Liesenfeld, Oliver

Small intestinal immunopathology following oral infection with tissue cysts of Toxoplasmagondii   has been described in C57BL/6 mice. Seven days after infection, mice develop severe small intestinal...

Aetiology of community-acquired, acute gastroenteritis in hospitalised adults: a prospective cohort study (2008)

Jansen, Andreas, Stark, Klaus, Kunkel, Jan, Schreier, Eckart, Ignatius, Ralf, Liesenfeld, Oliver, ...

Abstract Background The aetiology of severe gastroenteritis leading to hospitalisation in adults frequently remains unclear. Our objective was to study the causes and characteristics of...

Aetiology of community-acquired, acute gastroenteritis in hospitalised adults: a prospective cohort study (2008)

Jansen, Andreas, Stark, Klaus, Kunkel, Jan, Schreier, Eckart, Ignatius, Ralf, Liesenfeld, Oliver, ...

Background The aetiology of severe gastroenteritis leading to hospitalisation in adults frequently remains unclear. Our objective was to study the causes and characteristics of community-acquired,...

A new combined flow-cytometry-based assay reveals excellent activity against Toxoplasma gondii and low toxicity of new bisphosphonates in vitro and in vivo (2008)

Shubar, Hend M., Mayer, Jan Patino, Hopfenmüller, Werner, Liesenfeld, Oliver

Objectives The aim of this study was to investigate the antiparasitic activity and toxicity of bisphosphonates using a new combined flow cytometry assay. Methods Using Toxoplasma gondii tachyzoites...

Seroepidemiology of infection with Toxoplasma gondiiin healthy blood donors of Durango, Mexico (2007)

Alvarado-Esquivel, Cosme, Mercado-Suarez, Miguel, Rodríguez-Briones, Alfredo, Fallad-Torres, Laura, Ayala-Ayala, Julio, Nevarez-Piedra, Luis, ...

Abstract Background Toxoplasma gondii ( T. gondii ) infection in blood donors could represent a risk for transmission in blood recipients. There is scarce information about the epidemiology of T....

Waterborne toxoplasmosis, northeastern Brazil (2007)

Heukelbach, Jorg, Meyer-Cirkel, Vanessa, Moura, Rômulo César Sabóia, Gomide, Marcia, Queiroz, José Ajax Nogueira, Saweljew, Peter, ...

Two waterborne outbreaks of toxoplasmosis have been described recently in southern Brazil. We present data from a community-based study of pregnant women in northeastern Brazil. Consumption of...

Seroepidemiology of Toxoplasma gondiiinfection in psychiatric inpatients in a northern Mexican city (2006)

Alvarado-Esquivel, Cosme, Alanis-Quiñones, Olga-Patricia, Arreola-Valenzuela, Miguel-Ángel, Rodríguez-Briones, Alfredo, Piedra-Nevarez, Luis-Jorge, Duran-Morales, Ehecatl, ...

Abstract Background Patients with psychiatric disorders were found to show a high seroprevalence of Toxoplasma gondii infection. There is scarce information about the epidemiology of T. gondii...

Seroepidemiology of Toxoplasma gondiiinfection in pregnant women in a public hospital in northern Mexico (2006)

Alvarado-Esquivel, Cosme, Sifuentes-Álvarez, Antonio, Narro-Duarte, Sergio, Estrada-Martínez, Sergio, Díaz-García, Juan, Liesenfeld, Oliver, ...

Abstract Background Toxoplasma gondii ( T. gondii ) infection in pregnant women represents a risk for congenital disease. There is scarce information about the epidemiology of T. gondii infection in...

Expression of selectin ligands on murine effector and IL-10-producing CD4(+) T cells from non-infected and infected tissues (2004)

Kretschmer,Ute, Bonhagen,Kerstin, Debes,Gudrun F., Mittrucker,Hans-Willi, Erb,Klaus. J., Liesenfeld,Oliver, ...

Endothelial selectins are crucial for the recruitment of leukocytes into sites of inflammation. On T cells, ligands for selectins become induced upon differentiation into the effector/memory stage....

Atovaquone Maintenance Therapy Prevents Reactivation of Toxoplasmic Encephalitis in a Murine Model of Reactivated Toxoplasmosis (2004)

Ildiko R. Dunay, Markus M. Heimesaat, Faris Nadiem Bushrab, Rainer H. Müller, Hartmut Stocker, Keikawus Arasteh, ...

Acute therapy with pyrimethamine plus sulfadiazine is the treatment of choice for reactivated toxoplasmic encephalitis (TE). Acute therapy is followed by lifelong maintenance therapy (secondary...

Importance of Gender and Sex Hormones in Regulation of Susceptibility of the Small Intestine to Peroral Infection with Toxoplasma gondii Tissue Cysts (2001)

Oliver Liesenfeld, T. Anh Nguyen, Chandan Pharke, Yasuhiro Suzuki

This study was performed to investigate whether the gender and sex hormones play a role in susceptibility of the small intestine of mice to peroral infection with Toxoplasma gondii tissue cysts....

Targeted Inactivation of the Tetraspanin CD37 Impairs T-Cell-Dependent B-Cell Response under Suboptimal Costimulatory Conditions

Knobeloch, Klaus-Peter, Wright, Mark D., Ochsenbein, Adrian F., Liesenfeld, Oliver, Löhler, Jürgen, Zinkernagel, Rolf M., ...

CD37 is a membrane protein of the tetraspanin superfamily, which includes CD9, CD53, CD63, CD81, and CD82. Many of these molecules are expressed on leukocytes and have been implicated in signal...

Atovaquone Nanosuspensions Show Excellent Therapeutic Effect in a New Murine Model of Reactivated Toxoplasmosis

Schöler, Nadja, Krause, Karsten, Kayser, Oliver, Müller, Rainer H., Borner, Klaus, Hahn, Helmut, ...

Immunocompromised patients are at risk of developing toxoplasma encephalitis (TE). Standard therapy regimens (including sulfadiazine plus pyrimethamine) are hampered by severe side effects. While...

Cervical Cat Scratch Disease Lymphadenitis in a Patient with Immunoglobulin M Antibodies to Toxoplasma gondii

Arvand, Mardjan, Kazak, Ilkay, Jovanovic, Sergije, Foss, Hans-Dieter, Liesenfeld, Oliver

We report on a young patient with chronic cervical lymphadenopathy and serological and histological evidence for infection with Bartonella henselae and Toxoplasma gondii. Serological follow-up...

VIDAS Test for Avidity of Toxoplasma-Specific Immunoglobulin G for Confirmatory Testing of Pregnant Women

Montoya, Jose G., Liesenfeld, Oliver, Kinney, Sandra, Press, Cynthia, Remington, Jack S.

Because congenital toxoplasmosis is almost solely the result of maternal infection acquired during gestation, it is critical to determine whether infection during pregnancy has occurred. In the...

Infection with Toxoplasma gondii Reduces Established and Developing Th2 Responses Induced by Nippostrongylus brasiliensis Infection

Liesenfeld, Oliver, Dunay, Ildiko R., Erb, Klaus J.

Oral infection of C57BL/6 mice with 100 cysts of the protozoan parasite Toxoplasma gondii results in the development of small intestinal Th1-type immunopathology. In contrast, infection with...

Atovaquone Maintenance Therapy Prevents Reactivation of Toxoplasmic Encephalitis in a Murine Model of Reactivated Toxoplasmosis

Dunay, Ildiko R., Heimesaat, Markus M., Bushrab, Faris Nadiem, Müller, Rainer H., Stocker, Hartmut, Arasteh, Keikawus, ...

Acute therapy with pyrimethamine plus sulfadiazine is the treatment of choice for reactivated toxoplasmic encephalitis (TE). Acute therapy is followed by lifelong maintenance therapy (secondary...

European Multicenter Study of the LIAISON Automated Diagnostic System for Determination of Toxoplasma gondii-Specific Immunoglobulin G (IgG) and IgM and the IgG Avidity Index

Petersen, Eskild, Borobio, Maria Victoria, Guy, Edward, Liesenfeld, Oliver, Meroni, Valeria, Naessens, Anne, ...

The LIAISON system is a fully automated system based on chemiluminescence and antigen bound to magnetic microparticles. The system allows fast and precise measurement of Toxoplasma-specific...

Targeted Inactivation of the Tetraspanin CD37 Impairs T-Cell-Dependent B-Cell Response under Suboptimal Costimulatory Conditions

Knobeloch, Klaus-Peter, Wright, Mark D., Ochsenbein, Adrian F., Liesenfeld, Oliver, Löhler, Jürgen, Zinkernagel, Rolf M., ...

CD37 is a membrane protein of the tetraspanin superfamily, which includes CD9, CD53, CD63, CD81, and CD82. Many of these molecules are expressed on leukocytes and have been implicated in signal...

Atovaquone Nanosuspensions Show Excellent Therapeutic Effect in a New Murine Model of Reactivated Toxoplasmosis

Schöler, Nadja, Krause, Karsten, Kayser, Oliver, Müller, Rainer H., Borner, Klaus, Hahn, Helmut, ...

Immunocompromised patients are at risk of developing toxoplasma encephalitis (TE). Standard therapy regimens (including sulfadiazine plus pyrimethamine) are hampered by severe side effects. While...

Cervical Cat Scratch Disease Lymphadenitis in a Patient with Immunoglobulin M Antibodies to Toxoplasma gondii

Arvand, Mardjan, Kazak, Ilkay, Jovanovic, Sergije, Foss, Hans-Dieter, Liesenfeld, Oliver

We report on a young patient with chronic cervical lymphadenopathy and serological and histological evidence for infection with Bartonella henselae and Toxoplasma gondii. Serological follow-up...

VIDAS Test for Avidity of Toxoplasma-Specific Immunoglobulin G for Confirmatory Testing of Pregnant Women

Montoya, Jose G., Liesenfeld, Oliver, Kinney, Sandra, Press, Cynthia, Remington, Jack S.

Because congenital toxoplasmosis is almost solely the result of maternal infection acquired during gestation, it is critical to determine whether infection during pregnancy has occurred. In the...

Infection with Toxoplasma gondii Reduces Established and Developing Th2 Responses Induced by Nippostrongylus brasiliensis Infection

Liesenfeld, Oliver, Dunay, Ildiko R., Erb, Klaus J.

Oral infection of C57BL/6 mice with 100 cysts of the protozoan parasite Toxoplasma gondii results in the development of small intestinal Th1-type immunopathology. In contrast, infection with...

Atovaquone Maintenance Therapy Prevents Reactivation of Toxoplasmic Encephalitis in a Murine Model of Reactivated Toxoplasmosis

Dunay, Ildiko R., Heimesaat, Markus M., Bushrab, Faris Nadiem, Müller, Rainer H., Stocker, Hartmut, Arasteh, Keikawus, ...

Acute therapy with pyrimethamine plus sulfadiazine is the treatment of choice for reactivated toxoplasmic encephalitis (TE). Acute therapy is followed by lifelong maintenance therapy (secondary...

European Multicenter Study of the LIAISON Automated Diagnostic System for Determination of Toxoplasma gondii-Specific Immunoglobulin G (IgG) and IgM and the IgG Avidity Index

Petersen, Eskild, Borobio, Maria Victoria, Guy, Edward, Liesenfeld, Oliver, Meroni, Valeria, Naessens, Anne, ...

The LIAISON system is a fully automated system based on chemiluminescence and antigen bound to magnetic microparticles. The system allows fast and precise measurement of Toxoplasma-specific...

Selective mass treatment with ivermectin to control intestinal helminthiases and parasitic skin diseases in a severely affected population.

Heukelbach, Jörg, Winter, Benedikt, Wilcke, Thomas, Muehlen, Marion, Albrecht, Stephan, ...

OBJECTIVE: To assess the short-term and long-term impact of selective mass treatment with ivermectin on the prevalence of intestinal helminthiases and parasitic skin diseases in an economically...

Waterborne Toxoplasmosis, Northeastern Brazil

Heukelbach, Jorg, Meyer-Cirkel, Vanessa, Moura, Rômulo César Sabóia, Gomide, Márcia, Queiroz, José Ajax Nogueira, Saweljew, Peter, ...

Two waterborne outbreaks of toxoplasmosis have been described recently in southern Brazil. We present data from a community-based study of pregnant women in northeastern Brazil. Consumption of...