Enrichment of sequencing targets from the human genome by solution hybridization (2009)
Tewhey, Ryan, Nakano, Masakazu, Wang, Xiaoyun, Pabón-Peña, Carlos, Novak, Barbara, Giuffre, Angelica, ...
Abstract To exploit fully the potential of current sequencing technologies for population-based studies, one must enrich for loci from the human genome. Here we evaluate the hybridization-based...
Evaluation of next generation sequencing platforms for population targeted sequencing studies (2009)
Harismendy, Olivier, Ng, Pauline C, Strausberg, Robert L, Wang, Xiaoyun, Stockwell, Timothy B, Beeson, Karen Y, ...
Abstract Background Next generation sequencing (NGS) platforms are currently being utilized for targeted sequencing of candidate genes or genomic intervals to perform sequence-based association...
Genetic determinants of phenotypic diversity in humans (2008)
Rahim, Nazli G, Harismendy, Olivier, Topol, Eric J, Frazer, Kelly A
Abstract New technologies for rapidly assaying DNA sequences have revealed that the degree and nature of human genetic variation is far more complex then previously realized. These same technologies...
Genome-wide location of yeast RNA polymerase III transcription machinery
Harismendy, Olivier, Gendrel, Christiane-Gabrielle, Soularue, Pascal, Gidrol, Xavier, Sentenac, André, Werner, Michel, ...
RNA polymerase III (Pol III) transcribes a large set of genes encoding small untranslated RNAs like tRNAs, 5S rRNA, U6 snRNA or RPR1 RNA. To get a global view of class III (Pol III-transcribed)...
Genome-wide location of yeast RNA polymerase III transcription machinery
Harismendy, Olivier, Gendrel, Christiane-Gabrielle, Soularue, Pascal, Gidrol, Xavier, Sentenac, André, Werner, Michel, ...
RNA polymerase III (Pol III) transcribes a large set of genes encoding small untranslated RNAs like tRNAs, 5S rRNA, U6 snRNA or RPR1 RNA. To get a global view of class III (Pol III-transcribed)...
Maf1 Is Involved in Coupling Carbon Metabolism to RNA Polymerase III Transcription▿ †
Cieśla, Małgorzata, Towpik, Joanna, Graczyk, Damian, Oficjalska-Pham, Danuta, Harismendy, Olivier, Suleau, Audrey, ...
RNA polymerase III (Pol III) produces essential components of the biosynthetic machinery, and therefore its activity is tightly coupled with cell growth and metabolism. In the yeast Saccharomyces...
Genetic determinants of phenotypic diversity in humans
Rahim, Nazli G, Harismendy, Olivier, Topol, Eric J, Frazer, Kelly A
New techniques are enabling the identification of genetic variants underlying complex diseases and phenotypic traits.
Evaluation of next generation sequencing platforms for population targeted sequencing studies
Harismendy, Olivier, Ng, Pauline C, Strausberg, Robert L, Wang, Xiaoyun, Stockwell, Timothy B, Beeson, Karen Y, ...
Human sequence generated from three next-generation sequencing platforms reveals systematic variability in sequence coverage due to local sequence characteristics.