Olle Korsgren

Formation of composite endothelial cell-mesenchymal stem cell islets : a novel approach to promote islet revascularization (2008)

Johansson, Ulrika, Rasmusson, Ida, Niclou, Simone P., Forslund, Naomi, Gustavsson, Linda, Nilsson, Bo, ...

 OBJECTIVE: Mesenchymal stem cells (MSCs) contribute to endothelial cell (EC) migration by producing proteases, thereby paving the way into the tissues for ECs. MSCs were added to our previously...

Composite islet-endothelial cell grafts : a novel approach to counteract innate immunity in islet transplantation (2005)

Johansson, Ulrika, Elgue, Graciela, Nilsson, Bo, Korsgren, Olle

An instant blood-mediated inflammatory reaction (IBMIR) is elicited when islets come in contact with blood after intraportal transplantation. In contrast, endothelial cells (EC) readily tolerate...

Inflammatory mediators expressed in human islets of Langerhans : implications for islet transplantation (2003)

Johansson, Ulrika, Olsson, Annika, Gabrielsson, Susanne, Nilsson, Bo, Korsgren, Olle

Expression of immune modulating mediators in human Islets of Langerhans could have important implications for development of autoimmunity in type 1 diabetes and influence the outcome of clinical...

Natural Killer Cells Determine Development of Allergen-induced Eosinophilic Airway Inflammation in Mice

Korsgren, Magnus, Persson, Carl G.A., Sundler, Frank, Bjerke, Torbjörn, Hansson, Tony, Chambers, Benedict J., ...

The earliest contact between antigen and the innate immune system is thought to direct the subsequent antigen-specific T cell response. We hypothesized that cells of the innate immune system, such as...

Allergic Eosinophil-rich Inflammation Develops in Lungs and Airways of B Cell–deficient Mice

Korsgren, Magnus, ält, Jonas S. Erjef, Korsgren, Olle, Sundler, Frank, Persson, Carl G.A.

Immunoglobulins (Ig), particularly IgE, are believed to be crucially involved in the pathogenesis of asthma and, equally, in allergic models of the disease. To validate this paradigm we examined...

Formation of Composite Endothelial Cell–Mesenchymal Stem Cell Islets: A Novel Approach to Promote Islet Revascularization

Johansson, Ulrika, Rasmusson, Ida, Niclou, Simone P., Forslund, Naomi, Gustavsson, Linda, Nilsson, Bo, ...

OBJECTIVE—Mesenchymal stem cells (MSCs) contribute to endothelial cell (EC) migration by producing proteases, thereby paving the way into the tissues for ECs. MSCs were added to our previously...