Olle Lindvall

Long-Term Neuroblast Migration Along Blood Vessels in an Area With Transient Angiogenesis and Increased Vascularization After Stroke. (2007)

Thored, Par, Wood, James, Arvidsson, Andreas, Cammenga, Jorg, Kokaia, Zaal, Lindvall, Olle

Abstract is not available

Encapsulated cell biodelivery of GDNF: A novel clinical strategy for neuroprotection and neuroregeneration in Parkinson's disease? (2007)

Lindvall, Olle, Wahlberg, Lars U

Abstract is not available

Intranät som Informationssystem (2007)

Åkesson, Rikard, Lindvall, Olle

Informationssystemen är idag något som tar allt större plats i företagen världen över. Detta märkts framförallt genom de stora summor som varje år spenderas på olika former av...

Prostaglandin E(2) and BDNF levels in rat hippocampus are negatively correlated with status epilepticus severity: No impact on survival of seizure-generated neurons. (2006)

Ajmone-Cat, Maria Antonietta, Iosif, Robert E, Ekdahl, Christine T, Kokaia, Zaal, Minghetti, Luisa, Lindvall, Olle

Abstract is not available

Long-term neuronal replacement in adult rat hippocampus after status epilepticus despite chronic inflammation. (2006)

Bonde, Sara, Ekdahl, Christine T, Lindvall, Olle

Abstract is not available

Estimating the value of novel interventions for Parkinson's disease: An early decision-making model with application to dopamine cell replacement. (2006)

Hjelmgren, Jonas, Ghatnekar, Ola, Reimer, Jan, Grabowski, Martin, Lindvall, Olle, Persson, Ulf, ...

Abstract is not available

Regulation of stroke-induced neurogenesis in adult brain--recent scientific progress. (2006)

Kokaia, Zaal, Thored, Par, Arvidsson, Andreas, Lindvall, Olle

Abstract is not available

Intracerebral Infusion of Glial Cell Line-Derived Neurotrophic Factor Promotes Striatal Neurogenesis After Stroke in Adult Rats. (2006)

Kobayashi, Tohru, Ahlenius, Henrik, Thored, Par, Kobayashi, Rina, Kokaia, Zaal, Lindvall, Olle

Abstract is not available

Stem cells for the treatment of neurological disorders. (2006)

Lindvall, Olle, Kokaia, Zaal

Abstract is not available

Tumor necrosis factor receptor 1 is a negative regulator of progenitor proliferation in adult hippocampal neurogenesis. (2006)

Iosif, Robert E, Ekdahl, Christine T, Ahlenius, Henrik, Pronk, Cornelis J H, Bonde, Sara, Kokaia, Zaal, ...

Abstract is not available

Human fetal cortical and striatal neural stem cells generate region-specific neurons in vitro and differentiate extensively to neurons after intrastriatal transplantation in neonatal rats. (2006)

Kallur, Therése, Darsalia, Vladimer, Lindvall, Olle, Kokaia, Zaal

Abstract is not available

Environment Matters: Synaptic Properties of Neurons Born in the Epileptic Adult Brain Develop to Reduce Excitability. (2006)

Jakubs, Katherine, Nanobashvili, Avtandil, Bonde, Sara, Ekdahl, Christine T, Kokaia, Zaal, Kokaia, Merab, ...

Abstract is not available

Regulation of Stroke-Induced Neurogenesis in Adult Brain--Recent Scientific Progress (2006)

Kokaia, Zaal, Thored, Pär, Arvidsson, Andreas, Lindvall, Olle

Stroke induced by middle cerebral artery occlusion in adult rodents induces the formation of new neurons in the damaged striatum, a region that normally does not show neurogenesis. Here we describe...

Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning. (2005)

Mohapel, Paul, Leanza, Giampiero, Kokaia, Merab, Lindvall, Olle

Abstract is not available

Quantitative analysis of the generation of different striatal neuronal subtypes in the adult brain following excitotoxic injury. (2005)

Collin, Tove, Arvidsson, Andreas, Kokaia, Zaal, Lindvall, Olle

Abstract is not available

Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts. (2005)

Sørensen, Andreas Toft, Thompson, Lachlan, Kirik, Deniz, Björklund, Anders, Lindvall, Olle, Kokaia, Merab

Abstract is not available

Stroke-Induced Neurogenesis in Aged Brain. (2005)

Darsalia, Vladimer, Heldmann, Ursula, Lindvall, Olle, Kokaia, Zaal

Abstract is not available

Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor. (2005)

Ahn, Young-Hwan, Bensadoun, Jean-Charles, Aebischer, Patrick, Zurn, Anne D, Seiger, Ake, Björklund, Anders, ...

Abstract is not available

TNF-alpha antibody infusion impairs survival of stroke-generated neuroblasts in adult rat brain. (2005)

Heldmann, Ursula, Thored, Pär, Claasen, Jan-Hendrik, Arvidsson, Andreas, Kokaia, Zaal, Lindvall, Olle

Abstract is not available

Stem cell therapy for human brain disorders. (2005)

Lindvall, Olle, Kokaia, Zaal

Abstract is not available

Persistent production of neurons from adult brain stem cells during recovery after stroke. (2005)

Thored, Per, Arvidsson, Andreas, Cacci, Emanuele, Ahlenius, Henrik, Kallur, Therése, Darsalia, Vladimer, ...

Abstract is not available

Factors affecting the clinical outcome after neural transplantation in Parkinson's disease (2005)

Piccini, Paola, Pavese, Nicola, Hagell, Peter, Reimer, Jan, Björklund, Anders, Oertel, Wolfgang H., ...

Intrastriatal grafts of embryonic mesencephalic tissue can survive in the brains of patients with Parkinson's disease, but the degree of symptomatic relief is highly variable and some cases develop...

Status epilepticus severity influences the long-term outcome of neurogenesis in the adult dentate gyrus. (2004)

Mohapel, Paul, Ekdahl, Christine T, Lindvall, Olle

Abstract is not available

Stem cell therapy for human neurodegenerative disorders-how to make it work. (2004)

Lindvall, Olle, Kokaia, Zaal, Martinez-Serrano, Alberto

Abstract is not available

Recovery and Rehabilitation in Stroke. Stem Cells. (2004)

Lindvall, Olle, Kokaia, Zaal

Abstract is not available

Cell Therapy in Parkinson's Disease. (2004)

Lindvall, Olle, Björklund, Anders

Abstract is not available

Neurogenesis after ischaemic brain insults. (2003)

Kokaia, Zaal, Lindvall, Olle

Abstract is not available

Stem cells for cell therapy in Parkinson's disease. (2003)

Lindvall, Olle

Abstract is not available

Anterograde delivery of brain-derived neurotrophic factor to striatum via nigral transduction of recombinant adeno-associated virus increases neuronal death but promotes neurogenic response following stroke. (2003)

Gustafsson, Elin, Andsberg, Gunnar, Darsalia, Vladimer, Mohapel, Paul, Mandel, Ronald J., Kirik, Deniz, ...

Abstract is not available

Health status measurement in Parkinson's disease: Validity of the PDQ-39 and Nottingham Health Profile. (2003)

Hagell, Peter, Whalley, Diane, McKenna, Stephen P, Lindvall, Olle

Abstract is not available

Brain repair by cell replacement and regeneration. (2003)

Lindvall, Olle, McKay, Ron

Abstract not available.

Inflammation is detrimental for neurogenesis in adult brain. (2003)

Ekdahl, Christine T., Claasen, Jan-Hendrik, Bonde, Sara, Kokaia, Zaal, Lindvall, Olle

Abstract is not available

Intraventricular Infusion of TrkB-Fc Fusion Protein Promotes Ischemia-Induced Neurogenesis in Adult Rat Dentate Gyrus. (2003)

Gustafsson, Elin, Lindvall, Olle, Kokaia, Zaal

Abstract is not available

Elevated GDNF levels following viral vector-mediated gene transfer can increase neuronal death after stroke in rats. (2003)

Arvidsson, Andreas, Kirik, Deniz, Lundberg, Cecilia, Mandel, Ronald J, Andsberg, Gunnar, Kokaia, Zaal, ...

Abstract is not available

Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival. (2003)

Ekdahl, Christine T, Zhu, Changlian, Bonde, Sara, Bahr, Ben A, Blomgren, Klas, Lindvall, Olle

Abstract is not available

Neuropathological and behavioral consequences of adeno-associated viral vector-mediated continuous intrastriatal neurotrophin delivery in a focal ischemia model in rats. (2002)

Andsberg, Gunnar, Kokaia, Zaal, Klein, Ronald L, Muzyczka, Nicholas, Lindvall, Olle, Mandel, Ronald J

Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) were continuously delivered to the striatum at biologically active levels via recombinant adeno-associated viral (rAAV) gene...

Dyskinesias following neural transplantation in Parkinson's disease. (2002)

Hagell, Peter, Piccini, Paola, Björklund, Anders, Brundin, Patrik, Rehncrona, Stig, Widner, Håkan, ...

Severe dyskinesias during the 'off' phases (periods of increased Parkinson's disease (PD) disability) have been observed following intrastriatal transplantation of human embryonic mesencephalic...

Neuronal apoptosis after brief and prolonged seizures. (2002)

Bengzon, Johan, Mohapel, Paul, Ekdahl, Christine T, Lindvall, Olle

Evidence has accumulated that apoptotic cell death contributes to brain damage following experimental seizures. A substantial number of degenerating neurons within limbic regions display...

Neuronal replacement from endogenous precursors in the adult brain after stroke. (2002)

Arvidsson, Andreas, Collin, Tove, Kirik, Deniz, Kokaia, Zaal, Lindvall, Olle

In the adult brain, new neurons are continuously generated in the subventricular zone and dentate gyrus, but it is unknown whether these neurons can replace those lost following damage or disease....

Caspase-mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus. (2002)

Ekdahl, Christine T., Mohapel, Paul, Weber, Ekkehard, Bahr, Ben, Blomgren, Klas, Lindvall, Olle

A large proportion of cells that proliferate in the adult dentate gyrus under normal conditions or in response to brain insults exhibit only short-term survival. Here, we sought to determine which...

Suppression of insult-induced neurogenesis in adult rat brain by brain-derived neurotrophic factor. (2002)

Larsson, Elin, Mandel, Ronald J, Klein, Ronald L, Muzyczka, Nicholas, Lindvall, Olle, Kokaia, Zaal

Abstract is not available

Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry. (2002)

Englund, Ulrica, Bjorklund, Anders, Wictorin, Klas, Lindvall, Olle, Kokaia, Merab

Abstract is not available

Role of cell therapy in Parkinson disease. (2002)

Lindvall, Olle, Hagell, Peter

Abstract is not available

Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease (2000)

Brundin, Patrik, Pogarell, Oliver, Hagell, Peter, Piccini, Paola, Widner, Håkan, Schrag, Anette, ...

Five parkinsonian patients were transplanted bilaterally into the putamen and caudate nucleus with human embryonic mesencephalic tissue from between seven and nine donors. To increase graft survival,...

The glyoxylic acid fluorescence histochemical method for monoamines : chemistry, methodology and neuroanatomical application / (1974)

Lindvall, Olle.

Thesis (doctoral)--University of Lund, 1974.

Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor α2

Nanobashvili, Avtandil, Airaksinen, Matti S., Kokaia, Merab, Rossi, Jari, Asztély, Fredrik, Olofsdotter, Klara, ...

Seizure activity regulates gene expression for glial cell line-derived neurotrophic factor (GDNF) and neurturin (NRTN), and their receptor components, the transmembrane c-Ret tyrosine kinase and the...

Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures

Bengzon, Johan, Kokaia, Zaal, Elmér, Eskil, Nanobashvili, Avtandil, Kokaia, Merab, Lindvall, Olle

Neuronal apoptosis was observed in the rat dentate gyrus in two experimental models of human limbic epilepsy. Five hours after one hippocampal kindling stimulation, a marked increase of in situ...

Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin

Kokaia, Merab, Holmberg, Kristina, Nanobashvili, Avtandil, Xu, Zhi-Qing D., Kokaia, Zaal, Lendahl, Urban, ...

The neuropeptide galanin has been shown to suppress epileptic seizures. In cortical and hippocampal areas, galanin is normally mainly expressed in noradrenergic afferents. We have generated a mouse...

Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry

Englund, Ulrica, Björklund, Anders, Wictorin, Klas, Lindvall, Olle, Kokaia, Merab

In vitro expanded neural stem/progenitor cells can undergo region-specific differentiation after transplantation to the developing or adult brain, and display morphologies and markers characteristic...

Brain repair by cell replacement and regeneration

Lindvall, Olle, McKay, Ron

Inflammation is detrimental for neurogenesis in adult brain

Ekdahl, Christine T., Claasen, Jan-Hendrik, Bonde, Sara, Kokaia, Zaal, Lindvall, Olle

New hippocampal neurons are continuously generated in the adult brain. Here, we demonstrate that lipopolysaccharide-induced inflammation, which gives rise to microglia activation in the area where...

Cell Replacement Therapy: Helping the Brain to Repair Itself

Lindvall, Olle, Björklund, Anders

Cell Therapy in Parkinson's Disease

Lindvall, Olle, Björklund, Anders

Summary: The clinical studies with intrastriatal transplants of fetal mesencephalic tissue in Parkinson's disease (PD) patients have provided proof-of-principle for the cell replacement strategy in...

Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor α2

Nanobashvili, Avtandil, Airaksinen, Matti S., Kokaia, Merab, Rossi, Jari, Asztély, Fredrik, Olofsdotter, Klara, ...

Seizure activity regulates gene expression for glial cell line-derived neurotrophic factor (GDNF) and neurturin (NRTN), and their receptor components, the transmembrane c-Ret tyrosine kinase and the...

Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures

Bengzon, Johan, Kokaia, Zaal, Elmér, Eskil, Nanobashvili, Avtandil, Kokaia, Merab, Lindvall, Olle

Neuronal apoptosis was observed in the rat dentate gyrus in two experimental models of human limbic epilepsy. Five hours after one hippocampal kindling stimulation, a marked increase of in situ...

Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin

Kokaia, Merab, Holmberg, Kristina, Nanobashvili, Avtandil, Xu, Zhi-Qing D., Kokaia, Zaal, Lendahl, Urban, ...

The neuropeptide galanin has been shown to suppress epileptic seizures. In cortical and hippocampal areas, galanin is normally mainly expressed in noradrenergic afferents. We have generated a mouse...

Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry

Englund, Ulrica, Björklund, Anders, Wictorin, Klas, Lindvall, Olle, Kokaia, Merab

In vitro expanded neural stem/progenitor cells can undergo region-specific differentiation after transplantation to the developing or adult brain, and display morphologies and markers characteristic...

Brain repair by cell replacement and regeneration

Lindvall, Olle, McKay, Ron

Inflammation is detrimental for neurogenesis in adult brain

Ekdahl, Christine T., Claasen, Jan-Hendrik, Bonde, Sara, Kokaia, Zaal, Lindvall, Olle

New hippocampal neurons are continuously generated in the adult brain. Here, we demonstrate that lipopolysaccharide-induced inflammation, which gives rise to microglia activation in the area where...

Cell Replacement Therapy: Helping the Brain to Repair Itself

Lindvall, Olle, Björklund, Anders

Cell Therapy in Parkinson's Disease

Lindvall, Olle, Björklund, Anders

Summary: The clinical studies with intrastriatal transplants of fetal mesencephalic tissue in Parkinson's disease (PD) patients have provided proof-of-principle for the cell replacement strategy in...

Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

Parish, Clare L., Castelo-Branco, Gonçalo, Rawal, Nina, Tonnesen, Jan, Sorensen, Andreas Toft, Salto, Carmen, ...

Dopamine (DA) cell replacement therapy in Parkinson disease (PD) can be achieved using human fetal mesencephalic tissue; however, limited tissue availability has hindered further developments....