Aurrecoechea, Cristina, Brestelli, John, Brunk, Brian P., Carlton, Jane M., Dommer, Jennifer, Fischer, Steve, ...
GiardiaDB (http://GiardiaDB.org) and TrichDB (http://TrichDB.org) house the genome databases for Giardia lamblia and Trichomonas vaginalis, respectively, and represent the latest additions to the...
PlasmoDB: a functional genomic database for malaria parasites (2009)
Aurrecoechea, Cristina, Brestelli, John, Brunk, Brian P., Dommer, Jennifer, Fischer, Steve, Gajria, Bindu, ...
PlasmoDB (http://PlasmoDB.org) is a functional genomic database for Plasmodium spp. that provides a resource for data analysis and visualization in a gene-by-gene or genome-wide scale. PlasmoDB...
Aurrecoechea, Cristina, Brestelli, John, Brunk, Brian P., Carlton, Jane M., Dommer, Jennifer, Fischer, Steve, ...
© 2008 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License. The definitive version was published in Nucleic Acids...
Omar S. Harb, Bithi Chatterjee, Martin J. Fraunholz, Michael J. Crawford, Manami Nishi, David S. Roos
Most species of the protozoan phylum Apicomplexa harbor an endosymbiotic organelle—the apicoplast— acquired when an ancestral parasite engulfed a eukaryotic plastid-containing alga. Several...
Characterization of a Macrophage-Specific Infectivity Locus (milA) of Legionella pneumophila
Harb, Omar S., Abu Kwaik, Yousef
Legionella pneumophila has been shown to possess multiple genetic loci that play roles in its ability to survive within host cells. The mil (macrophage-specific infectivity loci) mutants of L....
Harb, Omar S., Abu Kwaik, Yousef
We have previously isolated 32 mutants of Legionella pneumophila that are defective in the infection of mammalian cells but not protozoa. The mutated loci have been designated macrophage-specific...
Invasion of Protozoa by Legionella pneumophila and Its Role in Bacterial Ecology and Pathogenesis
Abu Kwaik, Yousef, Gao, Lian-Yong, Stone, Barbara J., Venkataraman, Chandrasekar, Harb, Omar S.
Abu Kwaik, Yousef, Venkataraman, Chandrasekar, Harb, Omar S., Gao, Liang-Yong
The intracellular pathogens Legionella micdadei and Legionella pneumophila are the two most common Legionella species that cause Legionnaires’ disease. Intracellular replication within pulmonary...
Gao, Lian-Yong, Harb, Omar S., Kwaik, Yousef Abu
We have recently shown that many mutants of Legionella pneumophila exhibit similar defective phenotypes within both U937 human-derived macrophages and the protozoan host Acanthamoeba (L.-Y. Gao, O....
Harb, Omar S., Kwaik, Yousef Abu
The ability of Legionella pneumophila to cause Legionnaires’ disease is dependent on its capacity to survive in the intracellular environment of its host cells. Furthermore, outbreaks of this...
Harb, Omar S., Venkataraman, Chandrasekar, Haack, Bradley J., Gao, Lian-Yong, Kwaik, Yousef Abu
Invasion and intracellular replication of Legionella pneumophila within protozoa in the environment plays a major role in the transmission of Legionnaires’ disease. Intracellular replication of L....
Harb, Omar S., Chatterjee, Bithi, Fraunholz, Martin J., Crawford, Michael J., Nishi, Manami, Roos, David S.
Most species of the protozoan phylum Apicomplexa harbor an endosymbiotic organelle—the apicoplast—acquired when an ancestral parasite engulfed a eukaryotic plastid-containing alga. Several...
Vanchinathan, Padmini, Brewer, Jeremy L., Harb, Omar S., Boothroyd, John C., Singh, Upinder
During its life cycle in intermediate hosts, Toxoplasma gondii exists in two interconverting developmental stages: tachyzoites and bradyzoites. This interconversion is essential for the survival and...
Characterization of a Macrophage-Specific Infectivity Locus (milA) of Legionella pneumophila
Harb, Omar S., Abu Kwaik, Yousef
Legionella pneumophila has been shown to possess multiple genetic loci that play roles in its ability to survive within host cells. The mil (macrophage-specific infectivity loci) mutants of L....
Harb, Omar S., Abu Kwaik, Yousef
We have previously isolated 32 mutants of Legionella pneumophila that are defective in the infection of mammalian cells but not protozoa. The mutated loci have been designated macrophage-specific...
Invasion of Protozoa by Legionella pneumophila and Its Role in Bacterial Ecology and Pathogenesis
Abu Kwaik, Yousef, Gao, Lian-Yong, Stone, Barbara J., Venkataraman, Chandrasekar, Harb, Omar S.
Abu Kwaik, Yousef, Venkataraman, Chandrasekar, Harb, Omar S., Gao, Liang-Yong
The intracellular pathogens Legionella micdadei and Legionella pneumophila are the two most common Legionella species that cause Legionnaires’ disease. Intracellular replication within pulmonary...
Gao, Lian-Yong, Harb, Omar S., Kwaik, Yousef Abu
We have recently shown that many mutants of Legionella pneumophila exhibit similar defective phenotypes within both U937 human-derived macrophages and the protozoan host Acanthamoeba (L.-Y. Gao, O....
Harb, Omar S., Kwaik, Yousef Abu
The ability of Legionella pneumophila to cause Legionnaires’ disease is dependent on its capacity to survive in the intracellular environment of its host cells. Furthermore, outbreaks of this...
Harb, Omar S., Venkataraman, Chandrasekar, Haack, Bradley J., Gao, Lian-Yong, Kwaik, Yousef Abu
Invasion and intracellular replication of Legionella pneumophila within protozoa in the environment plays a major role in the transmission of Legionnaires’ disease. Intracellular replication of L....
Harb, Omar S., Chatterjee, Bithi, Fraunholz, Martin J., Crawford, Michael J., Nishi, Manami, Roos, David S.
Most species of the protozoan phylum Apicomplexa harbor an endosymbiotic organelle—the apicoplast—acquired when an ancestral parasite engulfed a eukaryotic plastid-containing alga. Several...
Vanchinathan, Padmini, Brewer, Jeremy L., Harb, Omar S., Boothroyd, John C., Singh, Upinder
During its life cycle in intermediate hosts, Toxoplasma gondii exists in two interconverting developmental stages: tachyzoites and bradyzoites. This interconversion is essential for the survival and...
Mining the Plasmodium genome database to define organellar function: what does the apicoplast do?
Roos, David S, Crawford, Michael J, Donald, Robert G K, Fraunholz, Martin, Harb, Omar S, He, Cynthia Y, ...
Apicomplexan species constitute a diverse group of parasitic protozoa, which are responsible for a wide range of diseases in many organisms. Despite differences in the diseases they cause, these...
Chen, ZhongQiang, Harb, Omar S., Roos, David S.
Apicomplexan parasites, including the human pathogens Toxoplasma gondii and Plasmodium falciparum, employ specialized secretory organelles (micronemes, rhoptries, dense granules) to invade and...
Aurrecoechea, Cristina, Brestelli, John, Brunk, Brian P., Carlton, Jane M., Dommer, Jennifer, Fischer, Steve, ...
GiardiaDB (http://GiardiaDB.org) and TrichDB (http://TrichDB.org) house the genome databases for Giardia lamblia and Trichomonas vaginalis, respectively, and represent the latest additions to the...
PlasmoDB: a functional genomic database for malaria parasites
Aurrecoechea, Cristina, Brestelli, John, Brunk, Brian P., Dommer, Jennifer, Fischer, Steve, Gajria, Bindu, ...
PlasmoDB (http://PlasmoDB.org) is a functional genomic database for Plasmodium spp. that provides a resource for data analysis and visualization in a gene-by-gene or genome-wide scale. PlasmoDB...