Ona C. Martin

The Exotoxin of P. aeruginosa: A Proenzyme Having an Unusual Mode of Activation (2006)

Leppla, Stephen H., Muehl, Laura A., Martin, Ona C.

The exotoxin of Pseudomonas aerguinosa is a proenzyme possessing latent ADPR-transferase activity. Conversion to the active form can be effected by simultaneous treatment with a protein denaturant...

Characterization of a New γTuRC Subunit with WD Repeats

Gunawardane, Ruwanthi N., Martin, Ona C., Zheng, Yixian

The γ-tubulin ring complex (γTuRC), consisting of multiple protein subunits, can nucleate microtubule assembly. Although many subunits of the γTuRC have been identified, a complete set remains to...

Characterization of a New γTuRC Subunit with WD Repeats

Gunawardane, Ruwanthi N., Martin, Ona C., Zheng, Yixian

The γ-tubulin ring complex (γTuRC), consisting of multiple protein subunits, can nucleate microtubule assembly. Although many subunits of the γTuRC have been identified, a complete set remains to...

Xgrip109: A γ Tubulin–Associated Protein with an Essential Role in γ Tubulin Ring Complex (γTuRC) Assembly and Centrosome Function

Martin, Ona C., Gunawardane, Ruwanthi N., Iwamatsu, Akihiro, Zheng, Yixian

Previous studies indicate that γ tubulin ring complex (γTuRC) can nucleate microtubule assembly and may be important in centrosome formation. γTuRC contains approximately eight subunits, which we...

Characterization of Two Related Drosophila γ-tubulin Complexes that Differ in Their Ability to Nucleate Microtubules

Oegema, Karen, Wiese, Christiane, Martin, Ona C., Milligan, Ronald A., Iwamatsu, Akihiro, Mitchison, Timothy J., ...

γ-tubulin exists in two related complexes in Drosophila embryo extracts (Moritz, M., Y. Zheng, B.M. Alberts, and K. Oegema. 1998. J. Cell Biol. 142:1– 12). Here, we report the purification and...

Characterization and Reconstitution of Drosophila γ-Tubulin Ring Complex Subunits

Gunawardane, Ruwanthi N., Martin, Ona C., Cao, Kan, Zhang, Lijun, Dej, Kimberly, Iwamatsu, Akihiro, ...

The γ-tubulin ring complex (γTuRC) is important for microtubule nucleation from the centrosome. In addition to γ-tubulin, the Drosophila γTuRC contains at least six subunits, three of which...