Detecting genetic variation in microarray expression data (2007)
Greenhall, Jennifer A., Zapala, Matthew A., Cáceres, Mario, Libiger, Ondrej, Barlow, Carrolee, Schork, Nicholas J., ...
The use of high-density oligonucleotide arrays to measure the expression levels of thousands of genes in parallel has become commonplace. To take further advantage of the growing body of data, we...
Generalized Analysis of Molecular Variance (2007)
Caroline M. Nievergelt, Ondrej Libiger, Nicholas J. Schork
Many studies in the fields of genetic epidemiology and applied population genetics are predicated on, or require, an assessment of the genetic background diversity of the individuals chosen for...
Hovatta, Iiris, Zapala, Matthew A, Broide, Ron S, Schadt, Eric E, Libiger, Ondrej, Schork, Nicholas J, ...
Abstract Background Expression quantitative trait locus (eQTL) mapping is used to find loci that are responsible for the transcriptional activity of a particular gene. In recent eQTL studies,...
Generalized Analysis of Molecular Variance (2007)
Caroline M Nievergelt, Ondrej Libiger, Nik J. Schork
Many studies in the fields of genetic epidemiology and applied population genetics are predicated on, or require, an assessment of the genetic background diversity of the individuals chosen for...
Simulation-based homozygosity mapping with the GAW14 COGA dataset on alcoholism (2005)
Libiger, Ondrej, Schork, Nicholas J
Abstract Background We have developed a simulation-based approach to the analysis of shared homozygous chromosomal segments and have applied it to data on allele sharing among alcoholics in a single...
Hovatta, Iiris, Zapala, Matthew A, Broide, Ron S, Schadt, Eric E, Libiger, Ondrej, Schork, Nicholas J, ...
Gene expression profiles of five brain regions from six inbred mouse strains suggest that many regulatory networks are highly specific to particular brain regions.
Generalized Analysis of Molecular Variance
Nievergelt, Caroline M, Libiger, Ondrej, Schork, Nicholas J
Many studies in the fields of genetic epidemiology and applied population genetics are predicated on, or require, an assessment of the genetic background diversity of the individuals chosen for...
Greenwood, Tiffany A., Libiger, Ondrej, Kardia, Sharon, Hanis, Craig, Morrison, Alanna C., Gu, C. Charles, ...
Linkage analyses of complex, multifactorial traits and diseases, such as essential hypertension, have been difficult to interpret and reconcile. Many published studies provide evidence suggesting...
Detecting genetic variation in microarray expression data
Greenhall, Jennifer A., Zapala, Matthew A., Cáceres, Mario, Libiger, Ondrej, Barlow, Carrolee, Schork, Nicholas J., ...
The use of high-density oligonucleotide arrays to measure the expression levels of thousands of genes in parallel has become commonplace. To take further advantage of the growing body of data, we...
Accommodating Linkage Disequilibrium in Genetic-Association Analyses via Ridge Regression
Malo, Nathalie, Libiger, Ondrej, Schork, Nicholas J.
Large-scale genetic-association studies that take advantage of an extremely dense set of genetic markers have begun to produce very compelling statistical associations between multiple makers...