Onni Niemelä

Publication List Details

Period

2000 - 2008

Number

13

Co-Authors

Modification of carbonic anhydrase II with acetaldehyde, the first metabolite of ethanol, leads to decreased enzyme activity (2008)

Bootorabi, Fatemeh, Jänis, Janne, Valjakka, Jarkko, Isoniemi, Sari, Vainiotalo, Pirjo, Vullo, Daniela, ...

Abstract Background Acetaldehyde, the first metabolite of ethanol, can generate covalent modifications of proteins and cellular constituents. However, functional consequences of such modification...

Insulin resistance and the progression of IgA glomerulonephritis (2007)

Kaartinen, Kati, Syrjänen, Jaana, Pörsti, Ilkka, Harmoinen, Aimo, Pasternack, Amos, Huhtala, Heini, ...

Background. IgA glomerulonephritis (IgAGN) has a highly variable prognosis with 15–40% of patients progressing to end-stage renal disease. Hypertension, proteinuria and renal insufficiency are risk...

High-calcium vs high-phosphate intake and small artery tone in advanced experimental renal insufficiency (2006)

Kööbi, Peeter, Vehmas, Tuija I., Jolma, Pasi, Kalliovalkama, Jarkko, Fan, Meng, Niemelä, Onni, ...

Background. Disturbed calcium-phosphorus balance significantly contributes to uraemic changes in large arteries. We examined the influences of high-calcium and high-phosphate intake on small artery...

Insulin resistance and the progression of IgA glomerulonephritis (2006)

Kaartinen, Kati, Syrjänen, Jaana, Pörsti, Ilkka, Harmoinen, Aimo, Pasternack, Amos, Huhtala, Heini, ...

Background. IgA glomerulonephritis (IgAGN) has a highly variable prognosis with 15–40% of patients progressing to end-stage renal disease. Hypertension, proteinuria and renal insufficiency are risk...

High-calcium vs high-phosphate intake and small artery tone in advanced experimental renal insufficiency (2006)

Kööbi, Peeter, Vehmas, Tuija I., Jolma, Pasi, Kalliovalkama, Jarkko, Fan, Meng, Niemelä, Onni, ...

Background. Disturbed calcium–phosphorus balance significantly contributes to uraemic changes in large arteries. We examined the influences of high-calcium and high-phosphate intake on small artery...

High-calcium vs high-phosphate intake and small artery tone in advanced experimental renal insufficiency (2006)

Kööbi, Peeter, Vehmas, Tuija I., Jolma, Pasi, Kalliovalkama, Jarkko, Fan, Meng, Niemelä, Onni, ...

Background. Disturbed calcium-phosphorus balance significantly contributes to uraemic changes in large arteries. We examined the influences of high-calcium and high-phosphate intake on small artery...

Insulin resistance and the progression of IgA glomerulonephritis (2006)

Kaartinen, Kati, Syrjänen, Jaana, Pörsti, Ilkka, Harmoinen, Aimo, Pasternack, Amos, Huhtala, Heini, ...

Background. IgA glomerulonephritis (IgAGN) has a highly variable prognosis with 15–40% of patients progressing to end-stage renal disease. Hypertension, proteinuria and renal insufficiency are risk...

METHOD-DEPENDENT CHARACTERISTICS OF CARBOHYDRATE-DEFICIENT TRANSFERRIN MEASUREMENTS IN THE FOLLOW-UP OF ALCOHOLICS (2004)

Anttila, Petra, Järvi, Kimmo, Latvala, Jaana, Niemelä, Onni

Aims: There are only limited data comparing the diagnostic characteristics of carbohydrate-deficient transferrin (CDT) measurements in assays for excessive alcohol consumption under controlled...

DIAGNOSTIC CHARACTERISTICS OF DIFFERENT CARBOHYDRATE-DEFICIENT TRANSFERRIN METHODS IN THE DETECTION OF PROBLEM DRINKING: EFFECTS OF LIVER DISEASE AND ALCOHOL CONSUMPTION (2003)

Anttila, Petra, Järvi, Kimmo, Latvala, Jaana, Blake, Joan E., Niemelä, Onni

Aims: Due to methodological heterogeneity, conflicting views have been expressed on the validity of CDT measurements in the detection of alcohol misuse. Methods: We compared the characteristics of...

EVIDENCE OF ACETALDEHYDE-PROTEIN ADDUCT FORMATION IN RAT BRAIN AFTER LIFELONG CONSUMPTION OF ETHANOL (2000)

Rintala, Jyrki, Jaatinen, Pia, Parkkila, Seppo, Sarviharju, Maija, Kiianmaa, Kalervo, Hervonen, Antti, ...

Acetaldehyde, the first metabolite of ethanol, has been shown to be capable of binding covalently to liver proteins in vivo, which may be responsible for a variety of toxic effects of ethanol....

Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig

Halsted, Charles H., Villanueva, Jesus A., Devlin, Angela M., Niemelä, Onni, Parkkila, Seppo, Garrow, Timothy A., ...

Alcoholic liver disease is associated with abnormal hepatic methionine metabolism and folate deficiency. Because folate is integral to the methionine cycle, its deficiency could promote alcoholic...

Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig

Halsted, Charles H., Villanueva, Jesus A., Devlin, Angela M., Niemelä, Onni, Parkkila, Seppo, Garrow, Timothy A., ...

Alcoholic liver disease is associated with abnormal hepatic methionine metabolism and folate deficiency. Because folate is integral to the methionine cycle, its deficiency could promote alcoholic...