An actin-based wave generator organizes cell motility (2007)
Weiner, Orion D, Marganski, William A, Wu, Lani F, Altschuler, Steven J, Kirschner, Marc W
Although many of the regulators of actin assembly are known, we do not understand how these components act together to organize cell shape and movement. To address this question, we analyzed the...
An Actin-Based Wave Generator Organizes Cell Motility (2007)
Orion D. Weiner, William A. Marganski, Lani F. Wu, Steven J. Altschuler, Marc W. Kirschner
Although many of the regulators of actin assembly are known, we do not understand how these components act together to organize cell shape and movement. To address this question, we analyzed the...
Orion D. Weiner, Maike C. Rentel, Alex Ott, Glenn E. Brown, Mark Jedrychowski, Michael B. Yaffe, ...
The authors describe a group of multiprotein complexes, scaffolded by Hem-1 (a subset of which also contain WAVE2), that are involved in generating and maintaining cellular polarity in neutrophils.
Orion D. Weiner, Maike C. Rentel, Alex Ott, Glenn E. Brown, Mark Jedrychowski, Michael B. Yaffe, ...
Migrating cells need to make different actin assemblies at the cell's leading and trailing edges and to maintain physical separation of signals for these assemblies. This asymmetric control of...
Dynamics of a Chemoattractant Receptor in Living Neutrophils during ChemotaxisV⃞
Servant, Guy, Weiner, Orion D., Neptune, Enid R., Sedat, John W., Bourne, Henry R.
Persistent directional movement of neutrophils in shallow chemotactic gradients raises the possibility that cells can increase their sensitivity to the chemotactic signal at the front, relative to...
Weiner, Orion D, Rentel, Maike C, Ott, Alex, Brown, Glenn E, Jedrychowski, Mark, Yaffe, Michael B, ...
Migrating cells need to make different actin assemblies at the cell's leading and trailing edges and to maintain physical separation of signals for these assemblies. This asymmetric control of...
Dynamics of a Chemoattractant Receptor in Living Neutrophils during ChemotaxisV⃞
Servant, Guy, Weiner, Orion D., Neptune, Enid R., Sedat, John W., Bourne, Henry R.
Persistent directional movement of neutrophils in shallow chemotactic gradients raises the possibility that cells can increase their sensitivity to the chemotactic signal at the front, relative to...
Weiner, Orion D, Rentel, Maike C, Ott, Alex, Brown, Glenn E, Jedrychowski, Mark, Yaffe, Michael B, ...
Migrating cells need to make different actin assemblies at the cell's leading and trailing edges and to maintain physical separation of signals for these assemblies. This asymmetric control of...
An Actin-Based Wave Generator Organizes Cell Motility
Weiner, Orion D, Marganski, William A, Wu, Lani F, Altschuler, Steven J, Kirschner, Marc W
Although many of the regulators of actin assembly are known, we do not understand how these components act together to organize cell shape and movement. To address this question, we analyzed the...