Center of Excellence and Departments of Medical (2008)
Oscar Millet, Anthony Mittermaier, David Baker, Lewis E. Kay, Genetics Biochemistry
The structural and dynamic properties of proteins are determined by their primary amino acid sequence. Elucidation of the rules that govern this relationship is of immense practical and
Tadeo, Xavier, Castaño, David, Millet, Oscar
The ability of three anionic cosolutes (sulfate, thiocyanate, and chloride) in modulating the 1H/2H exchange rates for backbone amide protons has been investigated using nuclear magnetic resonance...
Millet, Oscar, Hudson, Rhea P., Kay, Lewis E.
Maltose-binding protein (MBP) is a two-domain protein that undergoes a ligand-mediated conformational rearrangement from an “open” to a “closed” structure on binding to maltooligosaccharides....
Abu-Abed, Mona, Millet, Oscar, MacLennan, David H, Ikura, Mitsuhiko
In muscle cells, SERCA (sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase) plays a key role in restoring cytoplasmic Ca2+ levels to resting concentrations after transient surges caused by...
Millet, Oscar, Hudson, Rhea P., Kay, Lewis E.
Maltose-binding protein (MBP) is a two-domain protein that undergoes a ligand-mediated conformational rearrangement from an “open” to a “closed” structure on binding to maltooligosaccharides....
Abu-Abed, Mona, Millet, Oscar, MacLennan, David H, Ikura, Mitsuhiko
In muscle cells, SERCA (sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase) plays a key role in restoring cytoplasmic Ca2+ levels to resting concentrations after transient surges caused by...
Anion modulation of the 1H/2H exchange rates in backbone amide protons monitored by NMR spectroscopy
Tadeo, Xavier, Castaño, David, Millet, Oscar
The ability of three anionic cosolutes (sulfate, thiocyanate, and chloride) in modulating the 1H/2H exchange rates for backbone amide protons has been investigated using nuclear magnetic resonance...