Oskar Hoffmann

Late referral - a major cause of poor outcome in the very elderly dialysis patient (2006)

Schwenger, Vedat, Morath, Christian, Hofmann, Alex, Hoffmann, Oskar, Zeier, Martin, Ritz, Eberhard

Background. The population of incident dialysis patients is progressively ageing and dialysis outcome is particularly poor in the elderly. There is little documentation whether late referral is more...

Late referral - a major cause of poor outcome in the very elderly dialysis patient (2006)

Schwenger, Vedat, Morath, Christian, Hofmann, Alex, Hoffmann, Oskar, Zeier, Martin, Ritz, Eberhard

Background. The population of incident dialysis patients is progressively ageing and dialysis outcome is particularly poor in the elderly. There is little documentation whether late referral is more...

Late referral - a major cause of poor outcome in the very elderly dialysis patient (2006)

Schwenger, Vedat, Morath, Christian, Hofmann, Alex, Hoffmann, Oskar, Zeier, Martin, Ritz, Eberhard

Background. The population of incident dialysis patients is progressively ageing and dialysis outcome is particularly poor in the elderly. There is little documentation whether late referral is more...

Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src−/− mutant mice

Schwartzberg, Pamela L., Xing, Lianping, Hoffmann, Oskar, Lowell, Clifford A., Garrett, Lisa, Boyce, Brendan F., ...

The Src tyrosine kinase has been implicated in a wide variety of signal transduction pathways, yet despite the nearly ubiquitous expression of c-src, src−/− mice show only one major...

Essential role of RSK2 in c-Fos–dependent osteosarcoma development

David, Jean-Pierre, Mehic, Denis, Bakiri, Latifa, Schilling, Arndt F., Mandic, Vice, Priemel, Matthias, ...

Inactivation of the growth factor–regulated S6 kinase RSK2 causes Coffin-Lowry syndrome in humans, an X-linked mental retardation condition associated with progressive skeletal abnormalities. Here...

Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src−/− mutant mice

Schwartzberg, Pamela L., Xing, Lianping, Hoffmann, Oskar, Lowell, Clifford A., Garrett, Lisa, Boyce, Brendan F., ...

The Src tyrosine kinase has been implicated in a wide variety of signal transduction pathways, yet despite the nearly ubiquitous expression of c-src, src−/− mice show only one major...

Essential role of RSK2 in c-Fos–dependent osteosarcoma development

David, Jean-Pierre, Mehic, Denis, Bakiri, Latifa, Schilling, Arndt F., Mandic, Vice, Priemel, Matthias, ...

Inactivation of the growth factor–regulated S6 kinase RSK2 causes Coffin-Lowry syndrome in humans, an X-linked mental retardation condition associated with progressive skeletal abnormalities. Here...

TNF-induced structural joint damage is mediated by IL-1

Zwerina, Jochen, Redlich, Kurt, Polzer, Karin, Joosten, Leo, Krönke, Gerhard, Distler, Joerg, ...

Blocking TNF effectively inhibits inflammation and structural damage in human rheumatoid arthritis (RA). However, so far it is unclear whether the effect of TNF is a direct one or indirect on...

CD44 is a determinant of inflammatory bone loss

Hayer, Silvia, Steiner, Günter, Görtz, Birgit, Reiter, Erika, Tohidast-Akrad, Makiyeh, Amling, Michael, ...

Chronic inflammation is a major trigger of local and systemic bone loss. Disintegration of cell–matrix interaction is a prerequisite for the invasion of inflammatory tissue into bone. CD44 is a...