Baptista, J., Mercer, C., Prigmore, E., Gribble, S.M., Carter, N.P., Maloney, V., ...
We report the analyses of breakpoints in 31 phenotypically normal and 14 abnormal carriers of balanced translocations. Our study assesses the differences between balanced translocations in normal...
Genetic aspects of female reproduction (2008)
Collins, J., Diedrich, K., Franks, S., Geraedts, J.P.M., Jacobs, P.A., Karges, B., ...
BACKGROUND: Sexual reproduction provides the means for preserving genetic identity and in turn, genetic variability may affect the ability to reproduce. This review aims to summarize current research...
Migeon, B.R., Pappas, K., Stetten, G., Trunca, C., Jacobs, P.A.
Only one X chromosome functions in diploid human cells irrespective of the sex of the individual and the number of X chromosomes. Yet, as we show, more than one X is active in the majority of human...
Swerdlow, A.J., Schoemaker, M.J., Higgins, C.D., Wright, A.F., Jacobs, P.A.
The finding of increased risks of specific cancers in individuals with constitutional deletions of chromosomes 11p and 13q led to the discovery of cancer predisposition genes at these locations, but...
Investigation of the origins of human autosomal inversions (2008)
Thomas, N.S., Bryant, V., Maloney, V., Cockwell, A.E., Jacobs, P.A.
A significant proportion of both pericentric and paracentric inversions have recurrent breakpoints and so could either have arisen through multiple independent events or be identical by descent (IBD)...
Ennis, S., Murray, A., Brightwell, G., Morton, N.E., Jacobs, P.A.
In its expanded form, the fragile X triplet repeat at Xq27.3 gives rise to the most common form of inherited mental retardation, fragile X syndrome. This high population frequency persists despite...
X chromosome loss and ageing (2007)
Russell, L.M., Strike, P., Browne, C.E., Jacobs, P.A.
The detection of a low level 45,X cell line during routine cytogenetic analysis in an adult female can be difficult to interpret. In the absence of recent information regarding loss of the X...
Development of Casbar: a two-phase flow code for the interior ballsistics problem (2007)
Gollan, R.J., Johnston, I.A., O'Flaherty, B.T., Jacobs, P.A.
Accurate modelling of gun interior ballistic processes aids in the design and analysis of guns and their propelling charges. Presently, the most accurate modelling of the interior ballistics problem...
A simple data logger for student-designed rocket experiments. (2007)
The final-year project for Mechanical & Space Engineering students at UQ often involves the design and flight testing of an experiment. This report describes the design and use of a simple data...
Rough Notes on Programming AVR Microcontrollers in C (2007)
These notes follow on from the material that you studied in CSSE1000 Introduction to Computer Systems. There you studied details of logic gates, binary numbers and instruction set architectures using...
This report describes recent updates to the custom-built data-acquisition hardware operated by the Center for Hypersonics. In 2006, an ISA-to-USB bridging card was developed as part of Luke...
Development of Casbar: a Two-phase Flow Code for the Interior Ballistics Problem (2007)
Gollan, R. J., Johnston, I. A., O’Flaherty, B. T., Jacobs, P. A.
Accurate modelling of gun interior ballistic processes aids in the design and analysis of guns and their propelling charges. Presently, the most accurate modelling of the interior ballistics problem...
Simulation of CO2–N2 expansion tunnel flow for the study of radiating bluntbody shock layers (2007)
Potter, D. F., Gollan, R. J., Eichmann, T., Jacobs, P. A., Morgan, R. G., McIntyre, T. J.
A 25MJ/kg CO2–N2 expansion tunnel condition has been developed for the X2 impulse facility at the University of Queensland. A hybrid Lagrangian and Navier–Stokes computational simulation...
McGilvray, M., Austin, J. M., Sharma, M, Jacobs, P. A., Morgan, R. G.
Computational simulations of the AIR-1 test condition in the University of Illinois’ Hypervelocity Expansion Tube were conducted to verify facility operation and to obtain free stream properties...
Nonequilibrium radiation measurements and modelling relevant to Titan entry (2007)
Brandis, A. M., Morgan, R. G., Laux, C. O., Magin, T., McIntyre, T., Jacobs, P. A.
An update to a collisional-radiative model developed by Magin1 for Huygens Titan atmospheric entry is proposed. The model is designed to predict the nonequilibrium populations and the radiation...
Background oriented schlieren for flow visualisation in hypersonic impulse facilities (2007)
Ramanah, D., Raghunath, S., Mee, D. J., Rosgen, T., Jacobs, P. A.
Experiments to demonstrate the use of the background-oriented schlieren (BOS) technique in hypersonic impulse facilities are reported. BOS uses a simple optical set-up consisting of a structured...
Mundt, C., Boyce, R., Jacobs, P.A., Hannemann, K.
The simulation of high enthalpy flows, both experimentally and numerically, is a topic of international research efforts. It is important to understand and quantitatively describe the...
Nonequilibrium radiation measurements and modelling relevant to Titan entry (2007)
Brandis, A.M., Morgan, R.G., Laux, C.O., Magin, T., McIntyre, T.J., Jacobs, P.A.
Simulation of CO2-N2 expansion tunnel flow for the study of radiating bluntbody shock layers (2007)
Potter, D. F., Gollan, R. J., Eichmann, T., Jacobs, P. A., Morgan, R. G., McIntyre, T. J.
Background oriented schlieren for flow visualisation in hypersonic impulse facilities (2007)
Ramanah, D., Raghunath, S., Mee, D.J., Rosgen, T., Jacobs, P.A.
Development of casbar: a two-phase flow code for the interior ballistics problem (2007)
Gollan, R.J., Johnston, I.A., O'Flaherty, B.T., Jacobs, P.A.
Distribution of the D15Z1 copy number polymorphism (2007)
Cockwell, A.E., Jacobs, P.A., Crolla, J.A.
Using fluorescent in situ hybridization (FISH) with the probe p15 (D15Z1), we investigated the distribution of the polymorphic 15p signal which has been reported to occur on acrocentric chromosomes...
A simple data logger for student-designed rocket experiments. (2007)
The final-year project for Mechanical & Space Engineering students at UQ often involves the design and flight testing of an experiment. This report describes the design and use of a simple data...
Rough Notes on Programming AVR Microcontrollers in C (2007)
These notes follow on from the material that you studied in CSSE1000 Introduction to Computer Systems. There you studied details of logic gates, binary numbers and instruction set architectures using...
This report describes recent updates to the custom-built data-acquisition hardware operated by the Center for Hypersonics. In 2006, an ISA-to-USB bridging card was developed as part of Luke...
Development of Casbar: a Two-phase Flow Code for the Interior Ballistics Problem (2007)
Gollan, R. J., Johnston, I. A., O’Flaherty, B. T., Jacobs, P. A.
Accurate modelling of gun interior ballistic processes aids in the design and analysis of guns and their propelling charges. Presently, the most accurate modelling of the interior ballistics problem...
Simulation of CO2–N2 expansion tunnel flow for the study of radiating bluntbody shock layers (2007)
Potter, D. F., Gollan, R. J., Eichmann, T., Jacobs, P. A., Morgan, R. G., McIntyre, T. J.
A 25MJ/kg CO2–N2 expansion tunnel condition has been developed for the X2 impulse facility at the University of Queensland. A hybrid Lagrangian and Navier–Stokes computational simulation...
McGilvray, M., Austin, J. M., Sharma, M, Jacobs, P. A., Morgan, R. G.
Computational simulations of the AIR-1 test condition in the University of Illinois’ Hypervelocity Expansion Tube were conducted to verify facility operation and to obtain free stream properties...
Nonequilibrium radiation measurements and modelling relevant to Titan entry (2007)
Brandis, A. M., Morgan, R. G., Laux, C. O., Magin, T., McIntyre, T., Jacobs, P. A.
An update to a collisional-radiative model developed by Magin1 for Huygens Titan atmospheric entry is proposed. The model is designed to predict the nonequilibrium populations and the radiation...
Background oriented schlieren for flow visualisation in hypersonic impulse facilities (2007)
Ramanah, D., Raghunath, S., Mee, D. J., Rosgen, T., Jacobs, P. A.
Experiments to demonstrate the use of the background-oriented schlieren (BOS) technique in hypersonic impulse facilities are reported. BOS uses a simple optical set-up consisting of a structured...
Mundt, C., Boyce, R., Jacobs, P.A., Hannemann, K.
The simulation of high enthalpy flows, both experimentally and numerically, is a topic of international research efforts. It is important to understand and quantitatively describe the...
Development of Casbar: a two-phase flow code for the interior ballsistics problem (2007)
Gollan, R.J., Johnston, I.A., O'Flaherty, B.T., Jacobs, P.A.
Accurate modelling of gun interior ballistic processes aids in the design and analysis of guns and their propelling charges. Presently, the most accurate modelling of the interior ballistics problem...
Development of Casbar: a two-phase flow code for the interior ballsistics problem (2007)
Gollan, R.J., Johnston, I.A., O'Flaherty, B.T., Jacobs, P.A.
Accurate modelling of gun interior ballistic processes aids in the design and analysis of guns and their propelling charges. Presently, the most accurate modelling of the interior ballistics problem...
Development of Casbar: a two-phase flow code for the interior ballsistics problem (2007)
Gollan, R.J., Johnston, I.A., O'Flaherty, B.T., Jacobs, P.A.
Accurate modelling of gun interior ballistic processes aids in the design and analysis of guns and their propelling charges. Presently, the most accurate modelling of the interior ballistics problem...
An investigation of FRAXA intermediate allele phenotype in a longitudinal sample (2006)
Ennis, S., Murray, A., Youings, S., Brightwell, G., Herrick, D., Ring, S., ...
The FRAXA trinucleotide repeat at Xq27.3 gives rise to fragile X syndrome when fully expanded, and both premature ovarian failure (POF) and fragile X tremor and ataxia syndrome (FXTAS) when in the...
MBCNS2 is a small collection of programs for the simulation of transient two-dimensional (or axisymmetric) flows. It is part of the larger collection of compressible flow simulation codes found at...
Radiation measurements in nonreflected shock tunns (2006)
Morgan, R G, McIntyre, T J, Gollan, R. J., Jacobs, P A, Brandis, A. M., McGilvray, M., ...
Impulse facility simulation of hypervelocity radiating flows (2006)
Morgan, R. G., McIntyre, T. J., Jacobs, P. A., Buttsworth, D. R., Macrossan, M. N., Gollan, R. J., ...
Can trained monkeys design flight controllers for hypersonic vehicles? (2006)
A tongue-in-cheek title which formed a good metaphor for the design approach. Kevin Austin as PhD student of Peter Jacobs.
MBCNS2 is a small collection of programs for the simulation of transient two-dimensional (or axisymmetric) flows. It is part of the larger collection of compressible flow simulation codes found at...
Radiation measurements in nonreflected shock tunns (2006)
Morgan, R G, McIntyre, T J, Gollan, R. J., Jacobs, P A, Brandis, A. M., McGilvray, M., ...
Impulse facility simulation of hypervelocity radiating flows (2006)
Morgan, R. G., McIntyre, T. J., Jacobs, P. A., Buttsworth, D. R., Macrossan, M. N., Gollan, R. J., ...
Goozee, R. J., Jacobs, P. A., Buttsworth, D. R.
Simulations of a complete reflected shock tunnel facility have been performed with the aim of providing a better understanding of the flow through these facilities. In particular, the analysis is...
In situ space- and time-resolved sorption kinetics of anionic dyes on individual LDH crystals (2005)
Roeffaers, M. B. J., Sels, B. F., Loos, D., Kohl, C., Müllen, Klaus, Jacobs, P. A., ...
Scramjets and Shock Tunnels: The Queensland Experience (2005)
Stalker, R. J., Paull, A., Mee, D. J., Morgan, R. G., Jacobs, P. A.
This article reports on the use of a shock tunnel to study the operation of scramjet powered configurations at sub-orbital velocities above 2 km/s. Thrust, as given by a net thrust equation, is used...
Crolla, J.A., Youings, S.A., Ennis, S., Jacobs, P.A.
The details of all cytogenetic abnormalities diagnosed in the Wessex Regional Genetics Laboratory (WRGL) since 1967 to the present day have been recorded in the Salisbury Treasury of Interesting...
Gribble, S.M., Prigmore, E., Burford, D.C., Porter, K.M., Ng, B.L., Douglas, E.J., ...
OBJECTIVE: To describe the systematic analysis of constitutional de novo apparently balanced translocations in patients presenting with abnormal phenotypes, characterise the structural chromosome...
Scramjets and Shock Tunnels: The Queensland Experience (2005)
Stalker, R. J., Paull, A., Mee, D. J., Morgan, R. G., Jacobs, P. A.
This article reports on the use of a shock tunnel to study the operation of scramjet powered configurations at sub-orbital velocities above 2 km/s. Thrust, as given by a net thrust equation, is used...
Operating conditions in UQ's impulse facilities for scramjet testing (2005)
McGilvray, M., Morgan, R. G., Paull, A., Abdel-Jawad, M. M., Jacobs, P. A., McIntyre, T. J., ...
Superorbital expansion tube operation: Estimates of flow conditions via numerical simulation (2005)
Jacobs, P. A., Silvester, T. B., Morgan, R. G., Scott ,M .P., Golan, R. J., McIntyre, T. J.
Simulation of the Performance of the IISc Chemical Kinetics Shock Tube (2004)
Mee, D. J., Jacobs, P. A., Reddy, K. P. J., Rajakumar, B., Arunan, E.
This report presents the results of an investigation of the performance of the Chemical Kinetics Shock tube at the Indian Institute of Science. The one-dimensional Lagrangian code L1d of Jacobs...
Numerical modelling of radiating superorbital flows (2004)
Gollan, R. J., Jacobs, P. A., Karl, S., Smith, S. C.
Experimental aerodynamic studies of the flows around new aerocapture spacecraft configurations are presently being done in the superorbital expansion tubes at The University of Queensland. Short...
End-to-End modelling of the HEG Shock Tunnel (2004)
Jacobs, P. A., Gardner, A. D., Buttsworth, D. R., Schramm, J M, Karl, S, Hannemann, K.
Rarefied, superorbital flows in an expansion tube (2004)
Wheatley, Vincent, Chiu, S. H. H., Jacobs, P. A., Macrossan, M. N., Mee, D. J., Morgan, R. G.
This paper describes a free-piston driven expansion tube and its instrumentation. The facility is used to generate rarefied flows at speeds of approximately 10 km/s. Although the flow in the tube...
Rarefied, superorbital flows in an expansion tube (2004)
Wheatley, Vincent, Chiu, S. H. H., Jacobs, P. A., Macrossan, M. N., Mee, D. J., Morgan, R. G.
This paper describes a free-piston driven expansion tube and its instrumentation. The facility is used to generate rarefied flows at speeds of approximately 10 km/s. Although the flow in the tube...
Simulation of the Performance of the IISc Chemical Kinetics Shock Tube (2004)
Mee, D. J., Jacobs, P. A., Reddy, K. P. J., Rajakumar, B., Arunan, E.
This report presents the results of an investigation of the performance of the Chemical Kinetics Shock tube at the Indian Institute of Science. The one-dimensional Lagrangian code L1d of Jacobs...
Numerical modelling of radiating superorbital flows (2004)
Gollan, R. J., Jacobs, P. A., Karl, S., Smith, S. C.
Experimental aerodynamic studies of the flows around new aerocapture spacecraft configurations are presently being done in the superorbital expansion tubes at The University of Queensland. Short...
Experimental expansion tube study of the flow over a toroidal ballute (2004)
McIntyre, T. J., Lourel, I., Eichmann, T. N., Morgan, R. G., Jacobs, P. A., Bishop, A. I.
An experimental investigation of high-enthalpy flow over a toroidal ballute (balloon/parachute) was conducted in an expansion tube facility. The ballute, proposed for use in a number of future...
End-to-End modelling of the HEG Shock Tunnel (2004)
Jacobs, P. A., Gardner, A. D., Buttsworth, D. R., Schramm, J M, Karl, S, Hannemann, K.
Functional disomy resulting from duplications of distal Xq2 (2004)
Lachlan, K., Collinson, M.N., Sandford, R.O.C., Van Zyl, B., Jacobs, P.A., Thomas, N.S.
Tabiner, M., Youings, S., Dennis, N., Baldwin, D., Buis, C., Mayers, A., ...
Investigation of the co-occurrence of panic and phobic disorders with joint laxity led to the identification of various forms of interstitial duplications involving human chromosome 15q24-q26 (named...
Rocketdyne hypersonic flow laboratory as high performance expansion tube for scramjet testing (2003)
B S Stewart, R G Morgan, P A Jacobs
This paper was the result of Industrial collaboration and a SPIRT grant, and related to the possibility of using very large expansion tubes for sub orbital flow simulation. Subsequently, a major US...
Transient force measurements at superorbital speeds (2002)
Abdel-Jawad, M., Mee, D. J., Morgan, R. G., Jacobs, P.A., Philpot, J.A.
Development and application of a pressure-sensing electropalatograph (2002)
Rohde, A. H., Pienaar, G. L., Veidt, M., Jacobs, P.A., Murdoch, B. E., Goozee, J. V., ...
Transient force measurements at superorbital speeds (2002)
Abdel-Jawad, M., Mee, D. J., Morgan, R. G., Jacobs, P.A., Philpot, J.A.
Development and application of a pressure-sensing electropalatograph (2002)
Rohde, A. H., Pienaar, G. L., Veidt, M., Jacobs, P.A., Murdoch, B. E., Goozee, J. V., ...
Simulation of Oxford University Gun Tunnel performance using a quasi-one-dimensional model (2002)
Buttsworth, D. R., Jacobs, P. A., Jones, T. V.
The performance of the Oxford University Gun Tunnel has been estimated using a quasi-one-dimensional simulation of the facility gas dynamics. The modelling of the actual facility area variations so...
Maternal folate polymorphisms and the etiology of human nondisjunction (2001)
Hassold, T.J., Burrage, L.C., Chan, E.R., Judis, L.M., Schwartz, S., James, S.J., ...
Attempts to identify genetic contributors to human meiotic nondisjunction have met with little, if any, success. Thus, recent reports linking Down syndrome to maternal polymorphisms at either of two...
Establishment of test conditions in the RHYFL-X facility (2001)
Stewart, B. S., Morgan, R. G., Jacobs, P.A., Austin, K.J., Jenkins, D.M.
Swerdlow, A.J., Hermon, C., Jacobs, P.A., Alberman, E., Beral, V., Daker, M., ...
Mortality and cancer incidence were assessed in a cohort of 1373 patients with numerical sex chromosome abnormalities diagnosed at three cytogenetics centres in Britain during 1959-90, and were...
Establishment of test conditions in the RHYFL-X facility (2001)
Stewart, B. S., Morgan, R. G., Jacobs, P.A., Austin, K.J., Jenkins, D.M.
Flush air data system calibration using numerical simulation (1999)
Johnston, I., Jacobs, P. A., Shimoda, T.
The use of computational fluid dynamics simulations for calibrating a flush air data system is described, In particular, the flush air data system of the HYFLEX hypersonic vehicle is used as a case...
Simulation and optimization of heated, inviscid flows in scramjet ducts (1999)
A space-marching code for the simulation and optimization of inviscid supersonic flow in three dimensions is described. The now in a scramjet module with a relatively complex three-dimensional...
Flush air data system calibration using numerical simulation (1999)
Johnston, I., Jacobs, P. A., Shimoda, T.
The use of computational fluid dynamics simulations for calibrating a flush air data system is described, In particular, the flush air data system of the HYFLEX hypersonic vehicle is used as a case...
Simulation and optimization of heated, inviscid flows in scramjet ducts (1999)
A space-marching code for the simulation and optimization of inviscid supersonic flow in three dimensions is described. The now in a scramjet module with a relatively complex three-dimensional...
Zeolite encaged Cu(Histidine) complexes as a mimic of natural Cu-enzymes (1995)
Weckhuysen, B.M., Verberckmoes, A.A., Pelgrims, J.A., Buskens, P.L., Jacobs, P.A., Schoonheydt, R.A.
Cytogenetic and molecular studies of Down syndrome individuals with leukemia. (1995)
Shen, J J, Williams, B J, Zipursky, A, Doyle, J, Sherman, S L, Jacobs, P A, ...
There is an increased risk of leukemia in Down syndrome (DS) patients, with estimates ranging from 14 to 30 times the incidence rate observed for chromosomally normal children. Furthermore, one type...
Inspection Models and their application (1991)
THOMAS, L.C., GAVER, D.P, JACOBS, P.A.
Inspection involves examining deteriorating systems to try to identify their state, in order to effect some repair, replacement, or maintenance action. In many cases, one is able to monitor the...
Coalescence of stretching vortices (1985)
The contour dynamics numerical technique is used to study the coalescence of two equal uniform vortices in the presence of an externally applied stretching strain field. Plane three-dimensional...
Swerdlow, A. J., Jacobs, P. A., Marks, A., Maher, E. J., Young, T., Barber, J. C., ...
Reproductive outcomes and health of offspring were investigated in 340 patients with Hodgkin's disease first treated at Mount Vernon Hospital, Middlesex, England, at ages under 40 (females) or 45...
Cancer risk in patients with constitutional chromosome deletions: a nationwide British cohort study
Swerdlow, A J, Schoemaker, M J, Higgins, C D, Wright, A F, Jacobs, P A
The finding of increased risks of specific cancers in individuals with constitutional deletions of chromosomes 11p and 13q led to the discovery of cancer predisposition genes at these locations, but...