ADHD and DAT1: further evidence of paternal over-transmission of risk alleles and haplotype (2009)
Hawi, Z., Kent, L., Hill, M., Anney, R.J.L., Brookes, K.J., Barry, E., ...
We [Hawi et al. (2005); Am J Hum Genet 77:958-965] reported paternal over-transmission of risk alleles in some ADHD-associated genes. This was particularly clear in the case of the DAT1 3-UTR VNTR....
Sonuga-Barke, E., Oades, R.D., Psychogiou, L., Chen, W., Franke, B., Buitelaar, J., ...
Background: Mothers' positive emotions expressed about their children with attention deficit/hyperactivity disorder (ADHD) are associated with a reduced likelihood of comorbid conduct problems (CP)....
Genetic heterogeneity in ADHD: DAT1 gene only affects probands without CD (2008)
Zhou, K., Chen, W., Buitelaar, J., Banaschewski, T., Oades, R.D., Franke, B., ...
Previous studies have found heterogeneous association between DAT1-3-UTR-VNTR and attention deficit hyperactivity disorder (ADHD). Various proportions of conduct disorder (CD) comorbidity in their...
Replication of a rare protective allele in the noradrenaline transporter gene and ADHD (2008)
Xu, X., Hawi, Z., Brookes, K.J., Anney, R., Bellgrove, M., Franke, B., ...
Replication is a key to resolving whether a reported genetic association represents a false positive finding or an actual genetic risk factor. In a previous study screening 51 candidate genes for...
Brookes, K.J., Xu, X., Anney, R., Franke, B., Zhou, K., Chen, Wai, ...
Multiple studies have reported an association between attention deficit hyperactivity disorder (ADHD) and the 10-repeat allele of a variable number tandem repeat (VNTR) polymorphism in the...
Zhou, K., Asherson, P., Sham, P., Franke, B., Anney, R.J., Buitelaar, J., ...
Background Limited success has been achieved through previous attention-deficit/hyperactivity disorder (ADHD) linkage scans, which were all designed to map genes underlying the dichotomous phenotype....
Christiansen, H., Chen, W., Oades, R.D., Asherson, P., Taylor, E.A., Lasky-Su, J., ...
Common disorders of childhood and adolescence are attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD) and conduct disorder (CD). For one to two cases in three...
Asherson, P., Zhou, K., Anney, R.J.L., Franke, B., Buitelaar, J., Ebstein, R., ...
As part of the International Multi-centre ADHD Genetics project we completed an affected sibling pair study of 142 narrowly defined Diagnostic and Statistical Manual of Mental Disorders, fourth...
Brookes, K.J., Neale, B., Xu, X., Thapar, A., Gill, M., Langley, K., ...
Season of birth (SOB) has been associated with attention deficit hyperactivity disorder (ADHD) in two existing studies. One further study reported an interaction between SOB and genotypes of the...
Population differences in the international multi-centre ADHD gene project (2008)
Neale, B.M., Sham, P.C., Purcell, S., Banaschewski, T., Buitelaar, J., Franke, B., ...
The International Multi-Centre ADHD Gene sample consists of 674 families from eight countries (Belgium, England, Germany, Holland, Ireland, Israel, Spain, and Switzerland) ascertained from clinics...
Chen, W., Zhou, K., Sham, P., Franke, B., Kuntsi, J., Campbell, D., ...
Attention deficit hyperactivity disorder (ADHD) is a discrete clinical syndrome characterized by the triad of inattention, hyperactivity, and impulsivity in the context of marked impairments....
Xu, X., Aysimi, E., Anney, R., Brookes, K., Franke, B., Zhou, K., ...
Several independent studies have reported association between serotonin transporter gene (SLC6A4) polymorphisms and attention deficit hyperactivity disorder (ADHD). Five studies found evidence for...
Population differences in the International Multi-Centre ADHD Gene project (2008)
NEALE, BM, SHAM, PC, PURCELL, S, BANASCHEWSKI, T, BUITELAAR, J, FRANKE, B, ...
ASHERSON, P, ZHOU, K, ANNEY, RJL, FRANKE, B, BUITELAAR, J, EBSTEIN, R, ...
Genome-Wide Association Scan of Attention Deficit Hyperactivity Disorder (2008)
NEALE, BM, LASKY-SU, J, ANNEY, R, FRANKE, B, ZHOU, KX, MALLER, JB, ...
LASKY-SU, J, NEALE, BM, FRANKE, B, ANNEY, RJL, ZHOU, KX, MALLER, JB, ...
Genome-Wide Association Scan of the Time to Onset of Attention Deficit Hyperactivity Disorder (2008)
LASKY-SU, J, ANNEY, RJL, NEALE, BM, FRANKE, B, ZHOU, K, MALLER, JB, ...
ANNEY, RJL, HAWI, Z, SHEEHAN, K, MULLIGAN, A, PINTO, C, BROOKES, KJ, ...
Replication of a Rare Protective Allele in the Noradrenaline Transporter Gene and ADHD (2008)
XU, X, HAWI, Z, BROOKES, KJ, ANNEY, R, BELLGROVE, M, FRANKE, B, ...
ZHOU, KX, ASHERSON, P, SHAM, P, FRANKE, B, ANNEY, RJL, BUITELAAR, J, ...
Meta-Analysis of Genome-Wide Linkage Scans of Attention Deficit Hyperactivity Disorder (2008)
ZHOU, KX, DEMPFLE, A, ARCOS-BURGOS, M, BAKKER, SC, BANASCHEWSKI, T, BIEDERMAN, J, ...
Genetic Heterogeneity in ADHD: DAT1 Gene Only Affects Probands Without CD (2008)
ZHOU, KX, CHEN, W, BUITELAAR, J, BANASCHEWSKI, T, OADES, RD, FRANKE, B, ...
Brookes, K.J., Neale, B., Xu, X., Thapar, A., Gill, M., Langley, K., ...
Season of birth (SOB) has been associated with attention deficit hyperactivity disorder (ADHD) in two existing studies. One further study reported an interaction between SOB and genotypes of the...
Lasky-Su, J., Neale, B.M., Franke, B., Anney, R.J.L., Zhou, K., Maller, J.B., ...
Attention deficit hyperactivity disorder (ADHD) is a complex condition with environmental and genetic etiologies. Up to this point, research has identified genetic associations with candidate genes...
Lasky-Su, J., Banaschewski, T., Buitelaar, J., Franke, B., Brookes, K., Sonuga-Barke, E., ...
Background: Lisdexamfetamine dimesylate is a therapeutically inactive prodrug in which d-amphetamine is covalently bound to l-lysine, a naturally occurring amino acid. Pharmacologically active...
Lasky-Su, J., Banaschewski, T., Buitelaar, J., Franke, B., Brookes, K., Sonuga-Barke, E., ...
Background Previous research found an association between single nucleotide polymorphisms (SNPs) in the promoter region of DRD4 and statistically derived phenotypes generated from...
Nutt, D.J., Fone, P., Asherson, P., Bramble, D., Hill, P., Matthews, K., ...
Attention-deficit/hyperactivity disorder (ADHD) is an established diagnosis in children, associated with a large body of evidence on the benefits of treatment. Adolescents with ADHD are now leaving...
Nutt, D.J., Fone, K., Asherson, P., Bramble, D., Hill, P., Matthews, K., ...
Attention-deficit/hyperactivity disorder (ADHD) is an established diagnosis in children, associated with a large body of evidence on the benefits of treatment. Adolescents with ADHD are now leaving...
ASHERSON, P, BROOKES, K, FRANKE, B, CHEN, W, GILL, M, EBSTEIN, RP, ...
ANDREOU, P, NEALE, BM, CHEN, W, CHRISTIANSEN, H, GABRIELS, I, HEISE, A, ...
Brookes, K, Xu, X, Chen, W, Zhou, K, Neale, B, Lowe, N, ...
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, starting in early childhood and persisting into adulthood in the majority of cases. Family and twin studies...
Brookes, K., Xu, X., Chen, W., Zhou, K., Neale, B., Lowe, N., ...
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, starting in early childhood and persisting into adulthood in the majority of cases. Family and twin studies...
XU, XH, BROOKES, K, NEALE, B, CHEN, W, BUITELAAR, J, EBSTEIN, R, ...
Characterizing the ADHD phenotype for genetic studies. (2005)
Stevenson, J., Asherson, P., Hay, D., Levy, F., Swanson, J., Thapar, A., ...
The genetic study of ADHD has made considerable progress. Further developments in the field will be reliant in part on identifying the most appropriate phenotypes for genetic analysis. The use of...
European clinical guidelines for hyperkinetic disorder: first upgrade (2004)
Taylor, E., Döpfner, M., Sergeant, J., Asherson, P., Banaschewski, T., Buitelaar, J., ...
Background The validity of clinical guidelines changes over time, because new evidencebased knowledge and experience develop. Objective Hence, the European clinical guidelines on hyperkinetic...
Curran, S., Mill, J., Tahir, E., Kent, L., Richards, S., Gould, A., ...
Molecular genetic studies in attention deficit hyperactivity disorder (ADHD) have focussed on candidate genes within the dopamine system, which is thought to be the main site of action of stimulant...
Mill, J., Curran, S., Kent, L., Richard, S., Gould, A., Virdee, V., ...
Recent studies report association and linkage between attention deficit hyperactivity disorder (ADHD) and the 7-repeat allele of a 48 base-pair repeat in the dopamine D4 receptor gene (DRD4).1 We...
Curran, S., Mill, J., Tahir, E., Kent, L., Richards, S., Gould, A., ...
Molecular genetic studies in attention deficit hyperactivity disorder (ADHD) have focussed on candidate genes within the dopamine system, which is thought to be the main site of action of stimulant...
Mill, J., Curran, S., Kent, L., Richards, S., Gould, A., Virdee, V., ...
Recent studies report association and linkage between attention deficit hyperactivity disorder (ADHD) and the 7-repeat allele of a 48 base-pair repeat in the dopamine D4 receptor gene (DRD4).1 We...
DNA pooling identifies QTLs on chromosome 4 for general cognitive ability in children (1999)
Fisher, PJ, Turic, D, Williams, NM, McGuffin, P, Asherson, P, Ball, D, ...
Association between schizophrenia and homozygosity at the dopamine D3 receptor gene.
Crocq, M A, Mant, R, Asherson, P, Williams, J, Hode, Y, Mayerova, A, ...
Disturbances in dopamine neurotransmission have been postulated to underlie schizophrenia. We report data from two independent studies of a BalI polymorphism in the dopamine D3 receptor gene in...