P. Brennan

Publication List Details

Period

1990 - 2010

Number

29

Co-Authors

Vitamin D Pathway Genes, Diet, and Risk of Renal Cell Carcinoma (2010)

S. Karami, P. Brennan, M. Navratilova, D. Mates, D. Zaridze, V. Janout, ...

Mediated by binding to the high-affinity vitamin D receptor (VDR), vitamin D forms a heterodimer complex with the retinoid-X-receptor (RXR). Variation in both genes has been shown to modify renal...

Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics (2008)

Garcia-Closas, M., Hall, P., Nevanlinna, H., Pooley, K., Morrison, J., Richesson, D.A., ...

A three-stage genome-wide association study recently identified single nucleotide polymorphisms (SNPs) in five loci (fibroblast growth receptor 2 (FGFR2), trinucleotide repeat containing 9 (TNRC9),...

Renal cell carcinoma, occupational pesticide exposure and modification by glutathione S-transferase polymorphisms (2008)

Karami, S., Boffetta, P., Rothman, N., Hung, R. J., Stewart, T., Zaridze, D., ...

This study investigated associations between occupational pesticide exposure and renal cell carcinoma (RCC) risk. To follow-up on a previous report by Buzio et al., we also considered whether this...

Glutathione S-transferase polymorphisms, cruciferous vegetable intake and cancer risk in the Central and Eastern European Kidney Cancer Study (2007)

Moore, L.E., Brennan, P., Karami, S., Hung, R.J., Hsu, C., Boffetta, P., ...

High consumption of cruciferous vegetables has been associated with reduced kidney cancer risk in many studies. Isothiocyanates, thought to be responsible for the chemopreventive properties of this...

Interleukin-1{beta} induced activation of nuclear factor-{kappa}b can be inhibited by novel pharmacological agents in osteoarthritis (2007)

Lauder, S. N., Carty, S. M., Carpenter, C. E., Hill, R. J., Talamas, F., Bondeson, J., ...

Objectives. To investigate the importance of activation of the transcription factor, nuclear factor-κB (NF-κB) by interleukin-1β (IL-1β) and tumour necrosis factor-α (TNF-α) in the pathogenesis...

Interleukin-1{beta} induced activation of nuclear factor-{kappa}b can be inhibited by novel pharmacological agents in osteoarthritis (2007)

Lauder, S. N., Carty, S. M., Carpenter, C. E., Hill, R. J., Talamas, F., Bondeson, J., ...

Objectives. To investigate the importance of activation of the transcription factor, nuclear factor-κB (NF-κB) by interleukin-1β (IL-1β) and tumour necrosis factor-α (TNF-α) in the pathogenesis...

Interleukin-1{beta} induced activation of nuclear factor-{kappa}b can be inhibited by novel pharmacological agents in osteoarthritis (2007)

Lauder, S. N., Carty, S. M., Carpenter, C. E., Hill, R. J., Talamas, F., Bondeson, J., ...

Objectives. To investigate the importance of activation of the transcription factor, nuclear factor-κB (NF-κB) by interleukin-1β (IL-1β) and tumour necrosis factor-α (TNF-α) in the pathogenesis...

Second primary cancers among 109 000 cases of non-Hodgkin's lymphoma (2005)

Brennan, P, Scélo, G, Hemminki, K, Mellemkjaer, L, Tracey, E, Andersen, A, ...

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Second primary malignancies in patients with male breast cancer (2005)

Hemminki, K, Scélo, G, Boffetta, P, Mellemkjaer, L, Tracey, E, Andersen, A, ...

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Differential cognitive effects of colloid cysts in the third ventricle that spare or compromise the fornix (2000)

Aggleton, J. P., McMackin, D., Carpenter, K., Hornak, J., Kapur, N., Halpin, S., ...

A series of twelve cases, all of whom had received surgery for the removal of a colloid cyst in the third ventricle, was examined on a series of memory tests. The only consistent predictor of poor...

Behcet's disease: evaluation of a new instrument to measure clinical activity (1999)

Bhakta, B. B., Brennan, P., James, T. E., Chamberlain, M. A., Noble, B. A., Silman, A. J.

Objective. Behçet's disease (BD) is a rare multisystem disorder characterized by vasculitis. At present, there are no laboratory markers that correlate well with the clinical activity in BD. This...

NATURAL REMISSION IN INFLAMMATORY POLYARTHRITIS: ISSUES OF DEFINITION AND PREDICTION (1996)

HARRISON, B. J., SYMMONS, D. P. M., BRENNAN, P., BARRETT, E. M., SILMAN, A. J.

This paper reports the frequency and predictors of remission (no arthritis on examination and no treatment with second-line drugs or steroids within the previous 3 months) in 358 patients with early...

SURVIVAL FOLLOWING THE ONSET OF SCLERODERMA: RESULTS FROM A RETROSPECTIVE INCEPTION COHORT STUDY OF THE UK PATIENT POPULATION (1996)

BRYAN, C., HOWARD, Y., BRENNAN, P., BLACK, C., SILMAN, A.

Sclerodcrma is a multisystem disease which in many populations is reported to have a substantially reduced survival. One problem with many of the published studies is the inclusion of patients with...

VALIDITY AND RELIABILITY OF THREE METHODS USED IN THE DIAGNOSIS OF RAYNAUD'S PHENOMENON (1993)

BRENNAN, P., SILMAN, A., BLACK, C., BERNSTEIN, R., COPPOCK, J., MADDISON, P., ...

Three different assessment methods for the classification of Raynaud's phenomenon (RP) were compared. These were (i) a previously validated method using colour charts supplemented with a short...

RELIABILITY OF SKIN INVOLVEMENT MEASURES IN SCLERODERMA (1992)

BRENNAN, P., SILMAN, A., BLACK, C., BERNSTEIN, R., COPPOCK, J., MADDISON, P., ...

Two methods have been proposed to quantify the extent of skin involvement in scleroderma. These are (1) a scoring system which quantifies and summates this severity rating in 17 areas of skin surface...

Renal cell carcinoma, occupational pesticide exposure and modification by glutathione S-transferase polymorphisms

Karami, S., Boffetta, P., Rothman, N., Hung, R. J., Stewart, T., Zaridze, D., ...

This study investigated associations between occupational pesticide exposure and renal cell carcinoma (RCC) risk. To follow-up on a previous report by Buzio et al., we also considered whether this...

Anthropometric factors and breast cancer risk among urban and rural women in South India: a multicentric case–control study

Mathew, A, Gajalakshmi, V, Rajan, B, Kanimozhi, V, Brennan, P, Mathew, B S, ...

Breast cancer (BC) incidence in India is approximately twice as high in urban women than in rural women, among whom we investigated the role of anthropometric factors and body size. The study was...

Tobacco smoking, alcohol drinking and Hodgkin's lymphoma: a European multi-centre case–control study (EPILYMPH)

Besson, H, Brennan, P, Becker, N, De Sanjosé, S, Nieters, A, Font, R, ...

We analysed the effects of tobacco and alcohol in the aetiology of Hodgkin's lymphoma (HL), based on 340 cases and 2465 controls enrolled in Spain, France, Italy, Germany, Ireland and Czech Republic,...

Second primary cancers among 109 000 cases of non-Hodgkin's lymphoma

Brennan, P, Scélo, G, Hemminki, K, Mellemkjaer, L, Tracey, E, Andersen, A, ...

An analysis of other primary cancers in individuals with non-Hodgkin's lymphoma (NHL) can help to elucidate this cancer aetiology. In all, 109 451 first primary NHL were included in a pooled...

Golestan cohort study of oesophageal cancer: feasibility and first results

Pourshams, A, Saadatian-Elahi, M, Nouraie, M, Malekshah, A F, Rakhshani, N, Salahi, R, ...

To investigate the incidence of oesophageal cancer (EC) in the Golestan province of North-East Iran, we invited 1349 rural and urban inhabitants of Golestan province aged 35–80 to undergo extensive...

Second primary malignancies in patients with male breast cancer

Hemminki, K, Scélo, G, Boffetta, P, Mellemkjaer, L, Tracey, E, Andersen, A, ...

An international multicentre study of first and second primary neoplasms associated with male breast cancer was carried out by pooling data from 13 cancer registries. Among a total of 3409 men with...

Recent trends and future directions for lung cancer mortality in Europe

Brennan, P, Bray, I

Lung cancer mortality patterns throughout Europe are very heterogeneous and largely reflect past smoking habits. In order to clarify the changing patterns of lung cancer in Europe we have plotted the...

Second primary neoplasms following non-Hodgkin's lymphoma in New South Wales, Australia

Brennan, P, Coates, M, Armstrong, B, Colin, D, Boffetta, P

The incidence of non-Hodgkin's lymphoma (NHL) has been increasing rapidly over the last three decades. The reasons for this trend are not known although increasing exposure to sunlight has been...