Separable forms of reality monitoring supported by anterior prefrontal cortex (2007)
Simons, J.S., Henson, R.N.A., Gilbert, S.J., Fletcher, P.C.
Reality monitoring refers to the process of discriminating between internally- and externally-generated information. Two different tasks have often been used to assess this ability: a) memory for...
Ersche, K.D., Fletcher, P.C., Roiser, J.P., Fryer, T.D., London, M., Robbins, T.W., ...
Objective: Previously, we reported that opiate users enrolled in methadone treatment made ‘risky’ choices on a decision-making task following a loss of points compared with heroin users and...
Honey, G.D., Honey, R.A.E., Sharar, S.R., Turner, D.C., Pomarol-Clotet, E., Kumaran, D., ...
Rationale The precise nature of the impact of the N-methyl-d-aspartate antagonist, ketamine, upon human episodic memory, has yet to be elucidated fully. Objectives This study sought to assess the...
Distinct roles for lateral and medial anterior prefrontal cortex in contextual recollection. (2005)
Simons, J.S., Gilbert, S.J., Owen, A.M., Fletcher, P.C., Burgess, P.W.
A key feature of human recollection is the ability to remember details of the context in which events were experienced, as well as details of the events themselves. Previous studies have implicated a...
Anterior prefrontal cortex and the recollection of contextual information. (2005)
Simons, J.S., Owen, A.M., Fletcher, P.C., Burgess, P.W.
Recollective memory can involve the retrieval of many different kinds of contextual information, including where and when an event took place, as well as our thoughts and feelings at the time. The...
Fletcher, P.C., Anderson, J.M., Shanks, D.R., Honey, R., Carpenter, T.A., Donovan, T., ...
Learning depends on surprise and is not engendered by predictable occurrences. In this functional magnetic resonance imaging (fMRI) study of causal associative learning, we show that dorsolateral...
Brain (2001), 124, 849--881 INVITED REVIEW (2001)
this article, we review these findings and offer a new interpretation that is best judged by its success in explaining extant neuroimaging and neuropsychological data. takes heed of the broad...
Frontal lobes and human memory:insights from functional neuroimaging (2001)
Fletcher, P.C., Henson, R.N.A.
The new functional neuroimaging techniques, PET and functional MRI (fMRI), offer sufficient experimental flexibility and spatial resolution to explore the functional neuroanatomical bases of...
The role of the right anterior prefrontal cortex in episodic retrieval (2000)
Allan, K., Dolan, R.J., Fletcher, P.C., Rugg, M.D.
Regional brain activity was measured with H(2) (15)O PET while participants attempted to complete word-stem and word-fragment retrieval cues with previously studied words. The retrieval cue...
Gallagher, H.L., Happe, F., Brunswick, N., Fletcher, P.C., Frith, U., Frith, C.D.
Previous functional imaging studies have explored the brain regions activated by tasks requiring 'theory of mind'--the attribution of mental states. Tasks used have been primarily verbal, and it has...
The role of the prefrontal cortex in recognition memory and memory for source: An fMRI study (1999)
Rugg, M.D., Fletcher, P.C., Chua, P.M.L., Dolan, R.J.
We employed fMRI to index neural activity in prefrontal cortex during tests of recognition and source memory. At study, subjects were presented with words displayed either to the left or right of...
Neural correlates of memory retrieval during recognition memory and cued recall (1998)
Rugg, M.D., Fletcher, P.C., Allan, K., Frith, C.D., Frackowiak, R.S.J., Dolan, R.J.
Regional brain activity, measured by H215O PET, was investigated during recognition memory and word-stem cued recall of words in order to compare the neural correlates of two components of memory...
The functional roles of prefrontal cortex in episodic memory. II. Retrieval (1998)
Fletcher, P.C., Shallice, T., Frith, C.D., Frackowiak, R.S.J., Dolan, R.J.
Functional neuroimaging studies of memory retrieval show consistent activation of the right prefrontal and superior parietal cortex. We examined the specific role of the prefrontal cortex during...
The functional roles of prefrontal cortex in episodic memory. I. encoding (1998)
Fletcher, P.C., Shallice, T., Dolan, R.J.
Functional neuroimaging studies of episodic memory consistently report an association between memory encoding operations and left prefrontal cortex (PFC) activation. Encoding-related activation has...
Segregating the functions of human hippocampus
Strange, B. A., Fletcher, P. C., Henson, R. N. A., Friston, K. J., Dolan, R. J.
It is now accepted that hippocampal lesions impair episodic memory. However, the precise functional role of the hippocampus in episodic memory remains elusive. Recent functional imaging data...
Segregating the functions of human hippocampus
Strange, B. A., Fletcher, P. C., Henson, R. N. A., Friston, K. J., Dolan, R. J.
It is now accepted that hippocampal lesions impair episodic memory. However, the precise functional role of the hippocampus in episodic memory remains elusive. Recent functional imaging data...
Reinforcement and Reversal Learning in First-Episode Psychosis
Murray, G. K., Cheng, F., Clark, L., Barnett, J. H., Blackwell, A. D., Fletcher, P. C., ...
Background: Abnormalities in reinforcement learning and reversal learning have been reported in psychosis, possibly secondary to subcortical dopamine abnormalities. Methods: We studied simple...