P. C. Hawker

In vitro behavior of human intestinal mucosa. The influence of acetyl choline on ion transport.

Isaacs, P E, Corbett, C L, Riley, A K, Hawker, P C, Turnberg, L A

The possibility that the autonomic nervous system may influence the function of intestinal mucosa was investigated by assessing the effect of acetyl choline on ion transport in human intestine....

Optimal timing of operation for bleeding peptic ulcer: prospective randomised trial.

Morris, D L, Hawker, P C, Brearley, S, Simms, M, Dykes, P W, Keighley, M R

From October 1980 to September 1983 all patients with upper gastrointestinal bleeding were admitted to a centralised unit and investigated by early endoscopy. A total of 142 patients with a proved...

Colonic Crohn's disease and use of oral contraception.

Rhodes, J M, Cockel, R, Allan, R N, Hawker, P C, Dawson, J, Elias, E

The prevalence of use of oral contraception before the onset of disease was established in 100 consecutive women attending follow up clinics for inflammatory bowel disease. A significant excess of...

In vitro behavior of human intestinal mucosa. The influence of acetyl choline on ion transport.

Isaacs, P E, Corbett, C L, Riley, A K, Hawker, P C, Turnberg, L A

The possibility that the autonomic nervous system may influence the function of intestinal mucosa was investigated by assessing the effect of acetyl choline on ion transport in human intestine....

Optimal timing of operation for bleeding peptic ulcer: prospective randomised trial.

Morris, D L, Hawker, P C, Brearley, S, Simms, M, Dykes, P W, Keighley, M R

From October 1980 to September 1983 all patients with upper gastrointestinal bleeding were admitted to a centralised unit and investigated by early endoscopy. A total of 142 patients with a proved...

Colonic Crohn's disease and use of oral contraception.

Rhodes, J M, Cockel, R, Allan, R N, Hawker, P C, Dawson, J, Elias, E

The prevalence of use of oral contraception before the onset of disease was established in 100 consecutive women attending follow up clinics for inflammatory bowel disease. A significant excess of...

Intracellular electrolyte depletion in patients with ileostomies.

Turnberg, L A, Morris, A I, Hawker, P C, Herman, K J, Shields, R A, Horth, C E

Fourteen apparently healthy patients with ileostomies were found to be depleted of total exchangeable sodium and potassium, but had normal serum electrolyte concentrations and normal extracellular...

Study of ion transport across biopsies of ileostomy in vitro: search for evidence of intestinal 'adaptation' after colectomy.

Hawker, P C, Morris, A I, McKay, J, Turnberg, L A

To explore the possibility that small intestinal 'adaptation' may occur after colectomy we examined the ability of ileal mucosal biopsies, taken from patients with ileostomies, to transport...

Adenocarcinoma of the small intestine complicating Crohn's disease.

Hawker, P C, Gyde, S N, Thompson, H, Allan, R N

Adenocarcinoma of the small intestine is an uncommon complication of Crohn's disease. We report the clinical and pathological details of three cases diagnosed between 1968 and 1980 with a review of...

Management of enterocutaneous fistulae in Crohn's disease.

Hawker, P C, Givel, J C, Keighley, M R, Alexander-Williams, J, Allan, R N

The outcome among 39 patients with enterocutaneous fistulae complicating Crohn's disease has been reviewed. The patients were considered in two groups: (1) no disease - all were early postoperative...

The therapeutic dilatation of enteric strictures due to Crohn's disease.

Alexander-Williams, J., Allan, A., Morel, P., Hawker, P. C., Dykes, P. W., O'Connor, H.

The use of dilatation as a treatment of strictures due to Crohn's disease has hitherto received little attention. We report dilatation of small and large bowel strictures in twelve patients with...

The importance of laparotomy in the diagnosis and management of intestinal bleeding of obscure origin.

Brearley, S., Hawker, P. C., Dorricott, N. J., Lee, J. R., Ambrose, N. S., Silverman, S. H., ...

Thirty-seven patients who had had either a colonoscopy or a selective mesenteric angiogram while being investigated for severe or persistent gastrointestinal bleeding of obscure origin were reviewed....