Study of the Hindrance Effect in Sub-barrier Fusion Reactions (2009)
Notani, M., Davies, P., Bucher, B., Fang, X., Lamm, L., Ma, C., ...
We have measured the fusion cross sections of the 12C(13C, p)24Na reaction through off-line measurement of the beta-decay of 24Na using the beta-gamma coincidence method. Our new measurements in the...
Evaluation of Copper(2+) Affinities for the Prion Protein (2009)
Nadal, R. C., Davies, P., Brown, D. R., Viles, J. H.
The prion protein (PrP) is a cell-surface Cu2+ binding glcoprotein which call bind six copper ions. The role of Cu2+ in PrP function, misfolding, and prion disease has generated much interest;...
Deconvoluting the Cu2+ binding modes of full-length prion protein (2008)
Klewpatinond, M., Davies, P., Bowen, S., Brown, D. R., Viles, J. H.
Manganese binding to the prion protein (2008)
Brazier, M, Davies, P., Player, E, Marken, Frank, Viles, J. H., Brown, David
There is considerable evidence that the prion protein binds copper. However, there have also been suggestions that prion protein (PrP) binds manganese. We used isothermal titration calorimetry to...
DSTO program in Home-Made Explosives (HME) and Home-Made Incendiaries (HMI) (2008)
Ellis-Steinborner, S., Smith, M., Fitzgerald, M., Smith, M., Smit, K., Davies, P., ...
A scalable multi-watt mid-IR laser source (2008)
Hemming, A., Bennetts, S., Davidson, A., Rees, S., Richards, J., Carmody, N., ...
Davies, P., Watts, K., Kelly, S.M., Clark, C., Price, N.C., McEwan, I.J.
Poly-amino acid repeats, especially long stretches of glutamine (Q), are common features of transcription factors and cell-signalling proteins and are prone to expansion, resulting in...
Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes (2008)
Patel, A, MacMahon, S, Chalmers, J, Neal, B, Billot, L, Woodward, M, ...
The prevalence of Type 2 diabetes is increasing rapidly and is associated with significant cardiovascular adverse effects. The authors tested the hypothesis that, in patients with type II diabetes,...
Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes (2008)
Patel, A, MacMahon, S, Chalmers, J, Neal, B, Billot, L, Woodward, M, ...
The prevalence of Type 2 diabetes is increasing rapidly and is associated with significant cardiovascular adverse effects. The authors tested the hypothesis that, in patients with type II diabetes,...
DSTO program in Home-Made Explosives (HME) and Home-Made Incendiaries (HMI) (2008)
Ellis-Steinborner, S., Smith, M., Fitzgerald, M., Smith, M., Smit, K., Davies, P., ...
A scalable multi-watt mid-IR laser source (2008)
Hemming, A., Bennetts, S., Davidson, A., Rees, S., Richards, J., Carmody, N., ...
Schulz, U. G., Blamire, A. M., Corkill, R. G., Davies, P., Styles, P., Rothwell, P. M.
Previous studies suggest an abnormal cerebral cortical energy metabolism in migraineurs. If causally related to the pathophysiology of migraine, these abnormalities might show a dose–response...
AIM: To estimate over a 3-year period following the first release of rabbit haemorrhagic disease virus (RHDV) the prevalence of rabbit haemorrhagic disease (RHD) and the abundance of rabbits...
Saris, W., Blair, S., Van Baak, M., Eaton, S., Davies, P., Di Pietro, L., ...
A consensus meeting was held in Bangkok, 21–23 May 2002, where experts and young scientists in the field of physical activity, energy expenditure and bodyweight regulation discussed the...
Laboratory model studies of flushing of trapped salt water from a blocked tidal estuary (2001)
Coates, Michael, Guo, Y., Davies, P.
Results are presented from a series of laboratory model studies of the flushing of saline water from a partially- or fully-closed estuary. Experiments have been carried out to determine...
Labour markets, welfare, and the personal scope of employment law (2000)
The issues which confront those concerned with employment law, about the types of workers to whom employment laws apply, are highly relevant to the subject of labour markets and welfare. The...
Young, A., Dixey, J., Cox, N., Davies, P., Devlin, J., Emery, P., ...
Objectives. To assess the impact of rheumatoid arthritis (RA) on function and how this affects major aspects of patients' lives. Methods. The inception cohort of RA patients was...
Potential bias in Kaplan-Meier survival analysis applied to rheumatology drug studies (2000)
Utley, M., Gallivan, S., Young, A., Cox, N., Davies, P., Dixey, J., ...
Larsen scoring of digitized X-ray images (1999)
Solymossy, C., Dixey, J., Utley, M., Gallivan, S., Young, A., Cox, N., ...
Objective.To determine how Larsen scores from digitized X-rays compare to those from film originals. Methods.A hundred sets of radiographs of patients recruited with early rheumatoid arthritis (RA)...
A modified Mann-Whitney statistic is used to construct a permutation test for comparing samples of paired data from two populations when the population identities of each pair are uncertain. An...
Postnatal maturation of noradrenaline uptake and release in cat papillary muscles (1977)
TYNAN, M., DAVIES, P., SHERIDAN, D.
Catecholamine uptake and release have been studied in isolated right ventricular papillary muscles from kittens aged less than 24 hours, 16 to 18 days and 28 to 32 days. Under the age of 24 h...
DAPSONE IN RHEUMATOID ARTHRITIS (1976)
McCONKEY, B., DAVIES, P., CROCKSON, R. A., CROCKSON, A. P., BUTLER, M., CONSTABLE, T. J.
After a preliminary period of observation, 71 patients with consistently active rheumatoid arthritis (RA) were given dapsone 50 mg daily for one week, then 100 mg daily. There was a significant...
A FURTHER STUDY OF GENERAL ANAESTHESIA FOR CAESAREAN SECTION (1976)
CRAWFORD, J. S, JAMES, F. M, DAVIES, P, CRAWLEY, M
Methoxyflurane or trichloroethylene in concentrations of 0.2% or 0.1% used in anaesthesia for Caesarean section were compared. There were no differences in the acid-base state or the clinical...
A RETURN TO TRICHLOROETHYLENE FOR OBSTETRIC ANAESTHESIA (1975)
CRAWFORD, J. SELWYN, DAVIES, P.
A study of 405 patients revealed that the substitution of 0.1% trichloroethylene for 0.1% methoxyflurane in a previously established technique of anaesthesia led to no remarkable...
ANAESTHESIA FOR SECTION: FURTHER REFINEMENTS OF A TECHNIQUE (1973)
CRAWFORD, J. S., BURTON, MARILYN, DAVIES, P.
Data derived from three groups of “clinically acceptable ideal patients” undergoing elective Caesarean section have been explored. All were tilted laterally during operation. The mothers who had...
SIGNIFICANCE OF THE INDIVIDUAL COMPONENTS OF THE APGAR SCORE (1973)
CRAWFORD, J. S., DAVIES, P., PEARSON, J. F.
An analysis of the relationship between the individual components of the 1 min Apgar score, and of each of them with the acid-base status of the infant at delivery, is presented. It is based upon...
TIME AND LATERAL TILT AT CAESAREAN SECTION (1972)
CRAWFORD, J. SELWYN, MARILYN, BURTON, DAVIES, P.
One hundred and fifty “clinically acceptable ideal cases” undergoing elective Caesarean section under a standardized regimen of general anaesthesia were studied. In 87 cases the patient was...
The choice of variables in the design of experiments for linear regression (1969)
In this paper, a procedure is developed which can be used to decide if a doubtful variable should be included in an experiment to fit a linear model to a set of yields. The criterion of success of...
Randomised controlled trial of combined paracetamol and ibuprofen for fever
Erlewyn‐Lajeunesse, M D S, Coppens, K, Hunt, L P, Chinnick, P J, Davies, P, Higginson, I M, ...
A randomised open label study of the combined use of paracetamol and ibuprofen to rapidly reduce fever is reported. The advantage of using both medications is less than half a degree centigrade in...
Protein substitute dosage in PKU: how much do young patients need?
MacDonald, A, Chakrapani, A, Hendriksz, C, Daly, A, Davies, P, Asplin, D, ...
Immunological Studies in Acute Myeloid Leukaemia: PHA Responsiveness and Serum Inhibitory Factors
Walker, J. S., Davis, D., Davies, P., Freeman, C. B., Harris, R.
Sera from 16 of 20 patients with AML at some stage of the disease inhibited the in vitro PHA transformation of normal lymphocytes assessed by measuring the rate of DNA synthesis after 67-70 hours;...
Cuzick, J, Sasieni, P, Davies, P, Adams, J, Normand, C, Frater, A, ...
A systematic review of the available evidence on the role of HPV testing in cervical screening has been published by the Health Technology Assessment Committee of the UK Department of Health. The...