P. E. Isaacs

In vitro behavior of human intestinal mucosa. The influence of acetyl choline on ion transport.

Isaacs, P E, Corbett, C L, Riley, A K, Hawker, P C, Turnberg, L A

The possibility that the autonomic nervous system may influence the function of intestinal mucosa was investigated by assessing the effect of acetyl choline on ion transport in human intestine....

Mefenamic acid enteropathy.

Isaacs, P E, Sladen, G E, Filipe, I

The clinical, radiological, and histological features of two patients with severe intestinal damage induced by mefenamic acid and mimicking coeliac disease are described. Symptoms rapidly reverted on...

In vitro behavior of human intestinal mucosa. The influence of acetyl choline on ion transport.

Isaacs, P E, Corbett, C L, Riley, A K, Hawker, P C, Turnberg, L A

The possibility that the autonomic nervous system may influence the function of intestinal mucosa was investigated by assessing the effect of acetyl choline on ion transport in human intestine....

Mefenamic acid enteropathy.

Isaacs, P E, Sladen, G E, Filipe, I

The clinical, radiological, and histological features of two patients with severe intestinal damage induced by mefenamic acid and mimicking coeliac disease are described. Symptoms rapidly reverted on...

Linear IgA dermatosis, coeliac disease, and extraintestinal B cell lymphoma.

Kapur, A, Isaacs, P E, Kelsey, P R

Linear IgA dermatosis is a malignancy associated rare bullous disorder similar to dermatitis herpetiformis. Linear IgA dermatosis differs from dermatitis herpetiformis in that the IgA deposits in the...

Human intestinal ion transport in vitro.

Corbett, C L, Isaacs, P E, Riley, A K, Turnberg, L A

The transport of sodium and chloride across human jejunal and ileal mucosa was studied using an in vitro technique. Specimens of mucosa removed at operation were stripped of muscle coats, mounted in...

Failure of glucagon to influence ion transport across human jejunal and ileal mucosa in vitro.

Isaacs, P E, Turnberg, L A

Glucagon (90 to 880 pg.ml-1) failed to influence electrical activity or fluxes of sodium and chloride across human jejunal and ileal mucosa in vitro. These results suggest that the intestinal...

Comparison of the effects of medium and long chain triglyceride containing liquid meals on gall bladder and small intestinal function in normal man.

Ladas, S D, Isaacs, P E, Murphy, G M, Sladen, G E

We investigated the effects of medium (MCT) and long (LCT) chain triglyceride test meals on gall bladder contraction (using ultrasonography) and small intestinal bile acid concentrations and ileal...

Fasting and postprandial ileal function in adapted ileostomates and normal subjects.

Ladas, S D, Isaacs, P E, Murphy, G M, Sladen, G E

The output of 11 established ileostomies was compared with ileal flow measured by intestinal perfusion in five normal volunteers when fasting and during the ileal passage of test meals containing...

Human gastrointestinal absorption of acyclovir from tablet duodenal infusion and sipped solution.

Lewis, L D, Fowle, A S, Bittiner, S B, Bye, A, Isaacs, P E

On two occasions at least 1 week apart, nine healthy male volunteers were administered in random order either 2 X 200 mg (1.8 mmol) acyclovir tablets or 400 mg of acyclovir in 500 ml of 5% dextrose...