Rudwaleit, M, Landewe, Rene, Listing, J, Brandt, J, Braun, J, ...
Objective: Non-radiographic axial spondyloarthritis (SpA) is characterised by a lack of definitive radiographic sacroiliitis and is considered an early stage of ankylosing spondylitis. The objective...
Hypersound damping in vitreous silica measured by picosecond acoustics (2008)
Devos, A., Foret, M., Ayrinhac, S., Emery, P., Rufflé, B.
The attenuation of longitudinal acoustic phonons up to frequencies nearing 250 GHz is measured in vitreous silica with a picosecond optical technique. Taking advantage of interferences on the probe...
McGonagle, D., Tan, A. L., Madden, J., Taylor, L., Emery, P.
Objectives. This study assessed the utility of rituximab for the therapy of RA in a non-academic environment in a group of cases where anti-TNF was either not available or relatively contraindicated....
Coates, L. C., Cawkwell, L. S., Ng, N. W. F., Bennett, A. N., Bryer, D. J., Fraser, A. D., ...
Objective. To investigate the long-term response to biological therapies in AS in a real life clinical setting and to quantify non-response and response to ‘switching’ therapies in these cases....
Sustained response to anakinra in ankylosing spondylitis (2008)
Bennett, A. N., Tan, A. L., Coates, L. C., Emery, P., Marzo-Ortega, H., McGonagle, D.
Buch, M. H., Reece, R. J., Quinn, M. A., English, A., Cunnane, G., Henshaw, K., ...
Objectives. Clinical response to TNF-α blockade in the treatment of RA is heterogeneous. The study aims were to determine whether pre-treatment synovial cytokine expression predicted infliximab...
Emery, P., McInnes, I. B., Van Vollenhoven, R., Kraan, M. C.
Inflammation is the major factor driving the progression of structural damage in rheumatoid arthritis (RA); therefore, it is critical to achieve rapid suppression of inflammation to maximize disease...
Morgan, A.W., Hale, G., Richards, S.J., Waldmann, H., ...
Background: Immunological tolerance in humans using anti-T-cell monoclonal antibodies (mAbs) may be hampered by a pro-inflammatory microenvironment. All clinical trials of such therapies in...
English, A., Jones, E. A., Corscadden, D., Henshaw, K., Chapman, T., Emery, P., ...
Objectives. The utility of autologous chondrocytes for cartilage repair strategies in older subjects with osteoarthritis (OA) may be limited by both age-related and disease-associated decline in...
Jones, E, Field, S, English, A, Reece, R, Emery, P, McGonagle, D, ...
No abstract available.
Field, S, Jones, E, English, A, Burgoyne, C, Churchman, S, Reece, R, ...
No abstract available.
Circulating levels of IL-7 in rheumatoid arthritis (2007)
Churchman, S, Field, S, Burgoyne, C, Brown, A, Emery, P, Ponchel, F
No abstract available.
Coulthard, LR, Church, LD, Mathews, RJ, Churchman, S, Dickie, L, Buch, M, ...
No abstract available.
Brown, A. K., Roberts, T. E., Wakefield, R. J., Karim, Z., Hensor, E., O'Connor, P. J., ...
Objectives. The practice of musculoskeletal ultrasonography (MSKUS) by UK rheumatologists remains limited, despite their reported enthusiasm. This study aimed to investigate factors that may...
English, A, Mundy, J, Henshaw, K, Corscadden, D, ...
Denton, C.P., Merkel, P.A., Furst, D.E., Khanna, D., Emery, P., Hsu, V.M., ...
Objective: To evaluate CAT-192, a recombinant human antibody that neutralizes transforming growth factor 1 (TGF1), in the treatment of early-stage diffuse cutaneous systemic sclerosis (dcSSc)....
Tan, A. L., Benjamin, M., Toumi, H., Grainger, A. J., Tanner, S. F., Emery, P., ...
Objectives. Diffuse swelling of the distal interphalangeal (DIP) joint beyond the joint margin is a common feature of arthritis in psoriatic arthritis (PsA). The purpose of this study was to explore...
Brown, A. K., Roberts, T. E., O'Connor, P. J., Wakefield, R. J., Karim, Z., Emery, P.
Objectives. Musculoskeletal ultrasonography (MSKUS) has been described by some rheumatologists as the ‘stethoscope of the joint’. Such enthusiasm is supported by evidence confirming validity and...
Brown, A. K., Roberts, T. E., O'Connor, P. J., Wakefield, R. J., Karim, Z., Emery, P.
Objectives. Musculoskeletal ultrasonography (MSKUS) has been described by some rheumatologists as the ‘stethoscope of the joint’. Such enthusiasm is supported by evidence confirming validity and...
Brown, A. K., Roberts, T. E., O'Connor, P. J., Wakefield, R. J., Karim, Z., Emery, P.
Objectives. Musculoskeletal ultrasonography (MSKUS) has been described by some rheumatologists as the ‘stethoscope of the joint’. Such enthusiasm is supported by evidence confirming validity and...
Turner, D.E., Helliwell, P.S., Emery, P., Woodburn, J.
BACKGROUND Foot involvement occurs early in rheumatoid arthritis but the extent to which this impacts on the structure and function leading to impairment and foot related disability is unknown. The...
Turner, D.E., Helliwell, P.S., Emery, P., Woodburn, J.
BACKGROUND Foot involvement occurs early in rheumatoid arthritis but the extent to which this impacts on the structure and function leading to impairment and foot related disability is unknown. The...
De Vos, Ann; U0047938, Côte, Renaud; U0051201, Emery, P
We explore from both the theoretical and experimental points of view the influence of the laser wavelength on the strain pulses detected in thin transparent layers using the picosecond ultrasonic...
The Object Management Group Ontology Definition Metamodel (2006)
Colomb, R.M., Raymond, K, Hart, L, Emery, P, Welty, C, Xie, G.T., ...
Report of a submission being made to a major international software engineering standards group, the Object Management Group which ties together OMG standards with World-Wide Web Consortium and...
The Object Management Group Ontology Definition Metamodel (2006)
Colomb, R. M., Raymond, K., Hart, L., Emery, P., Welty, C., Xie, G., ...
Report of a submission being made to a major international software engineering standards group, the Object Management Group which ties together OMG standards with World-Wide Web Consortium and...
PHAM, T, LANDEWE, R, DOUGADOS, M, SIEPER, J, BRAUN, J, ...
The Object Management Group Ontology Definition Metamodel (2006)
Colomb, R. M., Raymond, K., Hart, L., Emery, P., Welty, C., Xie, G., ...
Report of a submission being made to a major international software engineering standards group, the Object Management Group which ties together OMG standards with World-Wide Web Consortium and...
Pham, T., Landewe, R., Dougados, M., Sieper, J., Braun, J., ...
Objectives: To determine the type and proportion of patients with ankylosing spondylitis who rheumatologists consider to be candidates for treatment with tumour necrosis factor (TNF)-blocking agents,...
Strand, V., Balbir-Gurman, A., Pavelka, K., Emery, P., Li, N., Yin, M., ...
Objectives. To evaluate the long-term impact on physical function of a single course of rituximab in rheumatoid factor, seropositive patients with active rheumatoid arthritis (RA) despite ongoing...
Lawson, C. A., Brown, A. K., Bejarano, V., Douglas, S. H., Burgoyne, C. H., Greenstein, A. S., ...
Objective. Our aim was to test the hypothesis that there is a deficit in the CD4+CD25high regulatory T-cell population in early rheumatoid arthritis (RA), either in size or functional activity....
Bansback, N. J., Ara, R., Barkham, N., Brennan, A., Fraser, A. D., Conway, P., ...
Objectives. Tumour necrosis factor (TNF) has been shown to improve the outcomes in patients with psoriatic arthritis (PsA). We estimate the long-term impact on health status of prescribing the TNF...
Tan, A. L., Benjamin, M., Toumi, H., Grainger, A. J., Tanner, S. F., Emery, P., ...
Objectives. Diffuse swelling of the distal interphalangeal (DIP) joint beyond the joint margin is a common feature of arthritis in psoriatic arthritis (PsA). The purpose of this study was to explore...
Strand, V., Balbir-Gurman, A., Pavelka, K., Emery, P., Li, N., Yin, M., ...
Objectives. To evaluate the long-term impact on physical function of a single course of rituximab in rheumatoid factor, seropositive patients with active rheumatoid arthritis (RA) despite ongoing...
Lawson, C. A., Brown, A. K., Bejarano, V., Douglas, S. H., Burgoyne, C. H., Greenstein, A. S., ...
Objective. Our aim was to test the hypothesis that there is a deficit in the CD4+CD25high regulatory T-cell population in early rheumatoid arthritis (RA), either in size or functional activity....
Quinn, M. A., Gough, A. K. S., Green, M. J., Devlin, J., Hensor, E. M. A., Greenstein, A., ...
Objective. Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been identified as highly specific for rheumatoid arthritis (RA). Studies suggest an association with radiographic outcome. The...
Shortening infusion times for infliximab administration (2006)
Buch, M. H., Bryer, D., Lindsay, S., Rees-Evans, B., Fairclough, A., Emery, P.
Bansback, N. J., Ara, R., Barkham, N., Brennan, A., Fraser, A. D., Conway, P., ...
Objectives. Tumour necrosis factor (TNF) has been shown to improve the outcomes in patients with psoriatic arthritis (PsA). We estimate the long-term impact on health status of prescribing the TNF...
Lawson, C. A., Brown, A. K., Bejarano, V., Douglas, S. H., Burgoyne, C. H., Greenstein, A. S., ...
Objective. Our aim was to test the hypothesis that there is a deficit in the CD4+CD25high regulatory T-cell population in early rheumatoid arthritis (RA), either in size or functional activity....
Bansback, N. J., Ara, R., Barkham, N., Brennan, A., Fraser, A. D., Conway, P., ...
Objectives. Tumour necrosis factor (TNF) has been shown to improve the outcomes in patients with psoriatic arthritis (PsA). We estimate the long-term impact on health status of prescribing the TNF...
Tan, A. L., Benjamin, M., Toumi, H., Grainger, A. J., Tanner, S. F., Emery, P., ...
Objectives. Diffuse swelling of the distal interphalangeal (DIP) joint beyond the joint margin is a common feature of arthritis in psoriatic arthritis (PsA). The purpose of this study was to explore...
Strand, V., Balbir-Gurman, A., Pavelka, K., Emery, P., Li, N., Yin, M., ...
Objectives. To evaluate the long-term impact on physical function of a single course of rituximab in rheumatoid factor, seropositive patients with active rheumatoid arthritis (RA) despite ongoing...
Morgan, A.W., Barrett, J.H., Griffiths, B., Subramanian, D., Robinson, J.I., Keyte, V.H., ...
The Fcγ receptors play important roles in the initiation and regulation of many immunological and inflammatory processes, and genetic variants (FCGR) have been associated with numerous autoimmune...
The assessment of mesenchymal stem cells in normal synovial fluid (2005)
Jones, EA, Henshaw, KT, Corscadden, D, Emery, P, ...
Karim, Z, Wakefield, R, Gerards, A H, ...
OBJECTIVES: To evaluate the safety and efficacy of adding ciclosporin A (CSA) to the treatment of patients with psoriatic arthritis (PsA) demonstrating an incomplete response to methotrexate (MTX)...
Ponchel, F, Brown, AK, Field, SL, Hensor, L, Emery, P, Isaacs, JD
No abstract available.
Ponchel, F, Brown, AK, Field, SL, Quinn, M, Conaghan, P, Emery, P, ...
No abstract available.
A role for IL-7 in regulating CD4+CD25highregulatory T cells (2005)
Lawson, CA, Brown, AK, Field, SL, Burgoyne, C, Emery, P, Isaacs, JD, ...
No abstract available.
Brown, A, Ponchel, F, Isaacs, J, Emery, P
No abstract available.
Rynne, M, Maclean, C, McDermott, MF, Emery, P
No abstract available.
Mackie, S, Robinson, JI, Barrett, JH, Lawson, CA, Martin, S, Haroon-Rashid, L, ...
No abstract available.
Mackie, S., Robinson, J.I., Barrett, J.H., Lawson, C.A., Martin, S., Haroon-Rashid, L., ...
Background Rheumatoid arthritis (RA) is an autoimmune disease that is thought to arise from a complex interaction between multiple genetic factors and environmental triggers. We have previously...
Mackie, S., Robinson, J.I., Barrett, J.H., Lawson, C.A., Martin, S., Haroon-Rashid, L., ...
Background Rheumatoid arthritis (RA) is an autoimmune disease that is thought to arise from a complex interaction between multiple genetic factors and environmental triggers. We have previously...
Conaghan, P., Bird, P., Ejbjerg, B., O’Connor, P., Peterfy, C., McQueen, F., ...
This paper presents the metacarpophalangeal (MCP) joint magnetic resonance images of the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas. The illustrations include synovitis in the MCP...
The EULAR–OMERACT rheumatoid arthritis MRI reference image atlas: the wrist joint (2005)
Ejbjerg, B., McQueen, F., Lassere, M., Haavardsholm, E., Conaghan, P., O’Connor, P., ...
This paper presents the wrist joint MR images of the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas. Reference images for scoring synovitis, bone oedema, and bone erosions according...
An introduction to the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas (2005)
Østergaard, M., Edmonds, J., McQueen, F., Peterfy, C., Lassere, M., Ejbjerg, B., ...
This article gives a short overview of the development and characteristics of the OMERACT rheumatoid arthritis MRI scoring system (RAMRIS), followed by an introduction to the use of the...
Pitfalls in scoring MR images of rheumatoid arthritis wrist and metacarpophalangeal joints (2005)
McQueen, F., Østergaard, M., Peterfy, C., Lassere, M., Ejbjerg, B., Bird, P., ...
This paper outlines the most important pitfalls which are likely to be encountered in the assessment of magnetic resonance images of the wrist and metacarpophalangeal joints in patients with...
The development of the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas (2005)
Bird, P., Conaghan, P., Ejbjerg, B., McQueen, F., Lassere, M., Peterfy, C., ...
Based on a previously developed rheumatoid arthritis MRI scoring system (OMERACT 2002 RAMRIS), the development team agreed which joints, MRI features, MRI sequences, and image planes would best...
Conaghan, P., Bird, P., Ejbjerg, B., O’Connor, P., Peterfy, C., McQueen, F., ...
This paper presents the metacarpophalangeal (MCP) joint magnetic resonance images of the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas. The illustrations include synovitis in the MCP...
The EULAR–OMERACT rheumatoid arthritis MRI reference image atlas: the wrist joint (2005)
Ejbjerg, B., McQueen, F., Lassere, M., Haavardsholm, E., Conaghan, P., O’Connor, P., ...
This paper presents the wrist joint MR images of the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas. Reference images for scoring synovitis, bone oedema, and bone erosions according...
An introduction to the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas (2005)
Østergaard, M., Edmonds, J., McQueen, F., Peterfy, C., Lassere, M., Ejbjerg, B., ...
This article gives a short overview of the development and characteristics of the OMERACT rheumatoid arthritis MRI scoring system (RAMRIS), followed by an introduction to the use of the...
Pitfalls in scoring MR images of rheumatoid arthritis wrist and metacarpophalangeal joints (2005)
McQueen, F., Østergaard, M., Peterfy, C., Lassere, M., Ejbjerg, B., Bird, P., ...
This paper outlines the most important pitfalls which are likely to be encountered in the assessment of magnetic resonance images of the wrist and metacarpophalangeal joints in patients with...
The development of the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas (2005)
Bird, P., Conaghan, P., Ejbjerg, B., McQueen, F., Lassere, M., Peterfy, C., ...
Based on a previously developed rheumatoid arthritis MRI scoring system (OMERACT 2002 RAMRIS), the development team agreed which joints, MRI features, MRI sequences, and image planes would best...
Minimal disease activity for rheumatoid arthritis: A preliminary definition (2005)
Wells, G. A., Boers, M., Shea, B., Brooks, P. M., Simon, L. S., Strand, C. V., ...
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of...
Minimal disease activity for rheumatoid arthritis: A preliminary definition (2005)
Wells, G. A., Boers, M., Shea, B., Brooks, P. M., Simon, L. S., Strand, C. V., ...
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of...
Minimal disease activity for rheumatoid arthritis: A preliminary definition (2005)
Wells, G. A., Boers, M., Shea, B., Brooks, P. M., Simon, L. S., Strand, C. V., ...
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of...
Recent advances in alcohol-induced adduct formation (2005)
Freeman, T. L., Tuma, D.J., Thiele, G.M., Klassen, L.W., Worrall, S., Niemela, O., ...
Minimal disease activity for rheumatoid arthritis: A preliminary definition (2005)
Wells, G. A., Boers, M., Shea, B., Brooks, P. M., Simon, L. S., Strand, C. V., ...
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of...
Recent advances in alcohol-induced adduct formation (2005)
Freeman, T. L., Tuma, D.J., Thiele, G.M., Klassen, L.W., Worrall, S., Niemela, O., ...
Minimal disease activity for rheumatoid arthritis: a preliminary definition (2005)
Wells, G. A., Boers, M., Shea, B., Brooks, P. M., Simon, L. S., Strand, C. V., ...
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of...
The unmet need for anti-tumour necrosis factor (anti-TNF) therapy in ankylosing spondylitis (2005)
Barkham, N., Kong, K. O., Tennant, A., Fraser, A., Hensor, E., Keenan, A. M., ...
Objectives. Anti-tumour necrosis factor (anti-TNF) therapy is effective in the treatment of ankylosing spondylitis (AS), but guidelines are needed because of the cost. The primary aim of this study...
Rhodes, L. A., Grainger, A. J., Thomas, C., Emery, P., Conaghan, P. G.
Objectives. Synovitis is common in osteoarthritis (OA) of the knee. In order to evaluate its importance, valid and reliable quantification methods are required. The aim of this study was to compare...
Quinn, M. A., Gough, A. K. S., Green, M. J., Devlin, J., Hensor, E. M. A., Greenstein, A., ...
Objective. Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been identified as highly specific for rheumatoid arthritis (RA). Studies suggest an association with radiographic outcome. The...
Shortening infusion times for infliximab administration (2005)
Buch, M. H., Bryer, D., Lindsay, S., Rees-Evans, B., Fairclough, A., Emery, P.
Rhodes, L. A., Grainger, A. J., Thomas, C., Emery, P., Conaghan, P. G.
Objectives. Synovitis is common in osteoarthritis (OA) of the knee. In order to evaluate its importance, valid and reliable quantification methods are required. The aim of this study was to compare...
Debridement of plantar callosities in rheumatoid arthritis: a randomized controlled trial (2005)
Davys, H. J., Turner, D. E., Helliwell, P. S., Conaghan, P. G., Emery, P., Woodburn, J.
Objective. To compare forefoot pain, pressure and function before and after normal and sham callus treatment in rheumatoid arthritis (RA). Patients and methods. Thirty-eight RA patients were randomly...
The unmet need for anti-tumour necrosis factor (anti-TNF) therapy in ankylosing spondylitis (2005)
Barkham, N., Kong, K. O., Tennant, A., Fraser, A., Hensor, E., Keenan, A. M., ...
Objectives. Anti-tumour necrosis factor (anti-TNF) therapy is effective in the treatment of ankylosing spondylitis (AS), but guidelines are needed because of the cost. The primary aim of this study...
Ponchel, F., Verburg, R.J., Bingham, S.J., Brown, A.K., Moore, J., Protheroe, A., ...
We previously demonstrated prolonged, profound CD4+ T-lymphopenia in rheumatoid arthritis (RA) patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de...
Ponchel, F., Verburg, R.J., Bingham, S.J., Brown, A.K., Moore, J., Protheroe, A., ...
We previously demonstrated prolonged, profound CD4+ T-lymphopenia in rheumatoid arthritis (RA) patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de...
Furst, Daniel E, Breedveld, F C, Kalden, J R, Smolen, J S, Burmester, G R, Bijlsma, JWJ, ...
As in previous years, the consensus group to consider the use of biological agents was constituted by rheumatologists from the Universities of Erlangen, Leiden, and Vienna in Europe in cooperation...
Ponchel, F., Verburg, R., Bingham, S., Brown, A., Moore, J., Protheroe, A., ...
We previously demonstrated prolonged, profound CD4+ T-lymphopenia in rheumatoid arthritis (RA) patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de...
True infliximab resistance in rheumatoid arthritis: a role for lymphotoxin α? (2004)
Buch, M.H., Conaghan, P., Quinn, M.A., Bingham, S.J., Veale, D., Emery, P.
Background: The combination of methotrexate and the anti-tumour necrosis factor (TNF) antibody infliximab is a very effective treatment for rheumatoid arthritis (RA). However, a proportion of...
Wakefield, R.J., Green, M.J., Marzo-Ortega, H., Conaghan, P., Gibbon, W.W., McGonagle, D., ...
Objective: To determine the prevalence of subclinical synovitis using ultrasound (US) imaging of both painful and asymptomatic joints, in patients with early (6 joints). Of the 826 asymptomatic...
True infliximab resistance in rheumatoid arthritis: a role for lymphotoxin α? (2004)
Buch, M.H., Conaghan, P., Quinn, M.A., Bingham, S.J., Veale, D., Emery, P.
Background: The combination of methotrexate and the anti-tumour necrosis factor (TNF) antibody infliximab is a very effective treatment for rheumatoid arthritis (RA). However, a proportion of...
Wakefield, R.J., Green, M.J., Marzo-Ortega, H., Conaghan, P., Gibbon, W.W., McGonagle, D., ...
Objective: To determine the prevalence of subclinical synovitis using ultrasound (US) imaging of both painful and asymptomatic joints, in patients with early (6 joints). Of the 826 asymptomatic...
The use of imaging and biomarkers in the assessment and follow-up of arthritis (2004)
No abstract available.
Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis (2004)
Edwards, J.C.W., Szczepanski, L., Szechinski, J., Filipowicz-Sosnowska, A., Emery, P., Close, D.R., ...
Background: An open-label study indicated that selective depletion of B cells with the use of rituximab led to sustained clinical improvements for patients with rheumatoid arthritis. To confirm these...
Development of the PsAQoL: a quality of life instrument specific to psoriatic arthritis (2004)
McKenna, S.P., Doward, L.C., Whalley, D., Tennant, A., Emery, P., Veale, D.J.
Background: Patient reported outcome measures used in studies of psoriatic arthritis (PsA) have been found to be inadequate for determining the impact of the disease from the patient’s perspective....
Development of the PsAQoL: a quality of life instrument specific to psoriatic arthritis (2004)
McKenna, S.P., Doward, L.C., Whalley, D., Tennant, A., Emery, P., Veale, D.J.
Background: Patient reported outcome measures used in studies of psoriatic arthritis (PsA) have been found to be inadequate for determining the impact of the disease from the patient’s perspective....
Wakefield, R. J., Green, M., Marzo-Ortega, H., Conaghan, P. G., Gibbon, W. W., McGonagle, D., ...
Copyright © 2004 by the BMJ Publishing Group Ltd.
Wakefield, R. J., Green, M., Marzo-Ortega, H., Conaghan, P. G., Gibbon, W. W., McGonagle, D., ...
Copyright © 2004 by the BMJ Publishing Group Ltd.
Snowden, JA, Passweg, J, Moore, JJ, Milliken, S, Cannell, P, Van Laar, JM, ...
Objective. Since 1996, autologous hemopoietic stem cell transplantation (HSCT) has been used to treat severe rheumatoid arthritis (RA). To date, published reports have been individual cases or series...
Usage scenarios and goals for ontology definition metamodel (2004)
Hart, L., Emery, P., Colomb, R. M., Raymond, K., Chang, D., Yiming, Y., ...
Usage scenarios and goals for ontology definition metamodel (2004)
Hart, L., Emery, P., Colomb, R. M., Raymond, K., Chang, D., Yiming, Y., ...
ISSAS: International Start TNF-blocker Study in Ankylosing Spondylitis (2004)
Pham, T, Landewe, R, Dougados, M, Burgos-Vargas, R, Collantes-Estevez, E, Edmonds, J, ...
Snowden, J. A., Passweg, J., Moore, J. J., Milliken, S., Cannell, P., Van Laar, J. M., ...
Objective. Since 1996, autologous hemopoietic stem cell transplantation (HSCT) has been used to treat severe rheumatoid arthritis (RA). To date, published reports have been individual cases or series...
Debridement of plantar callosities in rheumatoid arthritis: a randomized controlled trial (2004)
Davys, H. J., Turner, D. E., Helliwell, P. S., Conaghan, P. G., Emery, P., Woodburn, J.
Objective. To compare forefoot pain, pressure and function before and after normal and sham callus treatment in rheumatoid arthritis (RA). Patients and methods. Thirty-eight RA patients were randomly...
Bingham, S. J., Buch, M. H., Tennant, A., Emery, P.
Objective. To assess the impact of escalating conventional therapy in patients with RA who satisfy BSR/NICE criteria for biologics. Methods. A total of 308 consecutive patients referred to a...
Debridement of plantar callosities in rheumatoid arthritis: a randomized controlled trial (2004)
Davys, H. J., Turner, D. E., Helliwell, P. S., Conaghan, P. G., Emery, P., Woodburn, J.
Objective. To compare forefoot pain, pressure and function before and after normal and sham callus treatment in rheumatoid arthritis (RA). Patients and methods. Thirty-eight RA patients were randomly...
McGonagle, D, Jones, E, English, A, Emery, P
No abstract available.
Appelboom, T., Emery, P., Tant, L., Dumarey, N., Schoutens, A.
Objective. To study the frequency of technetium-99m-positive ciprofloxacin scans (Infecton scintigraphy) thought to be specific for bacterial DNA in patients with arthritis and to assess the clinical...
Wakefield, R. J., Goh, E., Conaghan, P. G., Karim, Z., Emery, P.
Objective. To document the practice of musculoskeletal ultrasound (US) by a sample of European rheumatologists attending an annual general meeting of the European League Against Rheumatism (EULAR)....
A simplified disease activity index for rheumatoid arthritis for use in clinical practice (2003)
Smolen, J. S., Breedveld, F. C., Schiff, M. H., Kalden, J. R., Emery, P., Eberl, G., ...
Objective. The objective of this study was to verify the usefulness of a simple disease activity index (SDAI) for rheumatoid arthritis (RA). Methods. The SDAI is the numerical sum...
Fc{gamma}RIIIA-158V and rheumatoid arthritis: a confirmation study (2003)
Morgan, A. W., Keyte, V. H., Babbage, S. J., Robinson, J. I., Ponchel, F., Barrett, J. H., ...
Objectives. To develop a robust assay for genotyping the FcγRIIIA-158V/F polymorphism and to confirm the putative association between the FcγRIIIA-158V allele and rheumatoid arthritis (RA)....
Appelboom, T., Emery, P., Tant, L., Dumarey, N., Schoutens, A.
Objective. To study the frequency of technetium-99m-positive ciprofloxacin scans (Infecton scintigraphy) thought to be specific for bacterial DNA in patients with arthritis and to assess the clinical...
Wakefield, R. J., Goh, E., Conaghan, P. G., Karim, Z., Emery, P.
Objective. To document the practice of musculoskeletal ultrasound (US) by a sample of European rheumatologists attending an annual general meeting of the European League Against Rheumatism (EULAR)....
Bingham, S. J., Buch, M. H., Tennant, A., Emery, P.
Objective. To assess the impact of escalating conventional therapy in patients with RA who satisfy BSR/NICE criteria for biologics. Methods. A total of 308 consecutive patients referred to a tertiary...
Fc{gamma}RIIIA-158V and rheumatoid arthritis: a confirmation study (2003)
Morgan, A. W., Keyte, V. H., Babbage, S. J., Robinson, J. I., Ponchel, F., Barrett, J. H., ...
Objectives. To develop a robust assay for genotyping the FcγRIIIA‐158V/F polymorphism and to confirm the putative association between the FcγRIIIA‐158V allele and rheumatoid...
Serum MMP-3 and MMP-1 and progression of joint damage in early rheumatoid arthritis (2003)
Green, M. J., Gough, A. K. S., Devlin, J., Smith, J., Astin, P., Taylor, D., ...
Objective. Expression and activation of matrix metalloproteinases such as MMP‐3 (stromelysin‐1) and MMP‐1 (collagenase‐1) are increased in patients...
Rheumatological ultrasound (2003)
Wakefield, R. J., Brown, A., O'Connor, P., Grainger, A., Karim, Z., McGonagle, D., ...
Parenteral methotrexate should be given before biological therapy (2003)
Bingham, S. J., Buch, M. H., Lindsay, S., Pollard, A., White, J., Emery, P.
Fc{gamma}RIIIA-158V and rheumatoid arthritis: a confirmation study (2003)
Morgan, A. W., Keyte, V. H., Babbage, S. J., Robinson, J. I., Ponchel, F., Barrett, J. H., ...
Objectives. To develop a robust assay for genotyping the FcγRIIIA-158V/F polymorphism and to confirm the putative association between the FcγRIIIA-158V allele and rheumatoid arthritis (RA)....
Appelboom, T., Emery, P., Tant, L., Dumarey, N., Schoutens, A.
Objective. To study the frequency of technetium-99m-positive ciprofloxacin scans (Infecton scintigraphy) thought to be specific for bacterial DNA in patients with arthritis and to assess the clinical...
Wakefield, R. J., Goh, E., Conaghan, P. G., Karim, Z., Emery, P.
Objective. To document the practice of musculoskeletal ultrasound (US) by a sample of European rheumatologists attending an annual general meeting of the European League Against Rheumatism (EULAR)....
Bingham, S. J., Buch, M. H., Tennant, A., Emery, P.
Objective. To assess the impact of escalating conventional therapy in patients with RA who satisfy BSR/NICE criteria for biologics. Methods. A total of 308 consecutive patients referred to a tertiary...
Choy, E. H. S., Panayi, G. S., Emery, P., Madden, S., Breedveld, F. C., Kraan, M. C., ...
Objective. Results of an earlier open‐label pilot study showed that 4162W94 was a relatively non‐depleting anti‐CD4 monoclonal antibody that induced >80%...
Robustness and generalizability of smallest detectable difference in radiological progression (2001)
Lassere, MND, Johnson, K, Bruynesteyn, K, Molenaar, E, Boonen, A, Verhoeven, A, ...
The smallest detectable difference (SDD) reflects that component of a measure statistically attributable to error from the measurement process itself. As such it is an irreducible component of the...
Robustness and generalizability of smallest detectable difference in radiological progression (2001)
Lassere, MND, Johnson, K, Bruynesteyn, K, Molenaar, E, Boonen, A, Verhoeven, A, ...
The smallest detectable difference (SDD) reflects that component of a measure statistically attributable to error from the measurement process itself. As such it is an irreducible component of the...
Autologous stem cell transplantation in rheumatoid arthritis (2001)
Snowden, JA, Moore, J, Passweg, JR, Cannell, P, Van Laar, J, Bingham, S, ...
WHO Collaborating Centre consensus meeting on anti-cytokine therapy in rheumatoid arthritis (2001)
Emery, P., Appelboom, T., Breedveld, F. C., Edelmann, E., Kekow, J., ...
Severe adult rheumatoid arthritis is a cause of progressive disability and increased mortality across Europe. A cure for the disease remains elusive, but control of symptoms and maintenance of...
Quinn, M. A., Conaghan, P. G., Emery, P.
Objective. The concepts of early intervention and early arthritis clinics for the management of rheumatoid arthritis (RA) were introduced almost a decade ago. The evidence for these is...
Synovial biopsy in arthritis research: five years of concerted European collaboration (2000)
Bresnihan, B., Tak, P.P., Emery, P., Klareskog, L., Breedveld, F.
Clinical protocol for monitoring of targeted therapies in rheumatoid arthritis (2000)
Geborek, P., Saxne, T., Emery, P., Panayi, G., Sturrock, R. D., Williams, B. D.
Young, A., Dixey, J., Cox, N., Davies, P., Devlin, J., Emery, P., ...
Objectives. To assess the impact of rheumatoid arthritis (RA) on function and how this affects major aspects of patients' lives. Methods. The inception cohort of RA patients was...
Emery, P., Breedveld, F. C., Lemmel, E. M., Kaltwasser, J. P., Dawes, P. T., Gömör, B., ...
Objective. To compare the clinical efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis (RA). Methods. In this multicentre, double‐blind...
Griffiths, B., Situnayake, R. D., Clark, B., Tennant, A., Salmon, M., Emery, P.
Objective. There are a significant number of patients with rheumatoid arthritis (RA) of North Indian or Pakistani origin (Asian) now living in the UK. RA has been poorly studied...
Potential bias in Kaplan-Meier survival analysis applied to rheumatology drug studies (2000)
Utley, M., Gallivan, S., Young, A., Cox, N., Davies, P., Dixey, J., ...
Yocum, D. E., Allard, S., Cohen, S. B., Emery, P., Flipo, R. M., Goobar, J., ...
Objective. To compare the safety, tolerability and efficacy of the new oral microemulsion formulation of cyclosporin A (CyA; Sandimmun Neoral®) and the original CyA formulation...
Larsen scoring of digitized X-ray images (1999)
Solymossy, C., Dixey, J., Utley, M., Gallivan, S., Young, A., Cox, N., ...
Objective.To determine how Larsen scores from digitized X-rays compare to those from film originals. Methods.A hundred sets of radiographs of patients recruited with early rheumatoid arthritis (RA)...
Brooks, P., Emery, P., Evans, J. F., Fenner, H., Hawkey, C. J., Patrono, C., ...
The International Consensus Meeting on the Mode of Action of COX-2 Inhibition (ICMMAC) brought together 17 international experts in arthritis, gastroenterology and pharmacology on 5–6 December...
A preliminary study of ultrasound aspiration of bone erosion in early rheumatoid arthritis (1999)
Mc Gonagle, D, Gibbon, W, O'Connor, P, Blythe, D, Wakefield, R, Green, M, ...
Pease, CT, Bhakta, BB, Devlin, J, Emery, P
Objective. To identify factors affecting prognosis in patients with late-onset rheumatoid arthritis (RA). Methods. A total of 400 patients with RA fulfilling the American College of Rheumatology...
Devlin, J, Wagstaff, K, Arthur, V, Emery, P
Objective. Methotrexate (MTX) is an increasingly popular anti-rheumatic drug with its usefulness limited by toxicity, most commonly gastrointestinal (GI). The aim of the study was to study the...
Recommendations for the registration of drugs used in the treatment of rheumatoid arthritis. (1998)
LEMMEL, EM, REID, DM, NUKI, G, AVOUAC, B, BARDIN, T, BOUVENOT, G, ...
DNA binding properties of a chemically synthesized DNA binding domain of hRFX1 (1998)
Cornille, F, Emery, P, Schuler, W, Lenoir, C, Mach, B, Roques, BP, ...
Adu, D, Pall, A, Luqmani, RA, Richards, NT, Howie, AJ, Emery, P, ...
Emery, P., Strubin, M., Hofmann, K., Bucher, P., Mach, B., Reith, W.
The RFX DNA binding domain is a novel motif that has been conserved in a growing number of dimeric DNA-binding proteins, having diverse regulatory functions, in eukaryotic organisms ranging from...
DEVLIN, J., LILLEY, J., GOUGH, A., HUISSOON, A., HOLDER, R., REECE, R., ...
Hand bone mineral density (BMD) measurement by dual-energy X-ray absorptiometry (DXA) has potential as a marker of progression in early rheumatoid arthritis (RA). We examined a DXA methodology and...
GORDON, C., MATTHEWS, N., SCHLESINGER, B. C., AKBAR, A. N., BACON, P. A., EMERY, P., ...
The aim of this study was to determine whether active systemic lupus erythematosus (SLE) is associated with recruitment of resting CD45RA+ T cells or reactivation of CD45RO+ memory T cells....
Training in Rheumatology (1996)
BLAKE, D., DIEPPE, P., EMERY, P., MADDISON, P., NUKI, G., PANAYI, G. S., ...
The genetic origin of responses to drugs (1995)
Individual variation in drug metabolism has been extensively investigated. Population studies have shown that there is a wide range in metabolising ability for all detoxification pathways; the...
JANSSEN, B. A., LUQMANI, R. A., GORDON, C., HEMINGWAY, I. H., BACON, P. A., GEARING, A. J. H., ...
Levels of soluble adhesion molecules have been shown to reflect their cell surface expression in vitro, and thus may provide a useful surrogate marker of surface expression at inflammatory sites. In...
POSTERIOR SCLERITIS--AN UNUSUAL MANIFESTATION OF COGAN'S SYNDROME (1994)
SHAH, P., LUQMANI, R. A., MURRAY, P. I., HONAN, W. P., CORRIDAN, P. G. J., EMERY, P.
Cogan's syndrome is characterized by a non-luetic interstitial keratitis associated with vertigo, tinnitus and profound deafness. Evidence of a systemic vasculitis is found in up to 50% of...
Birmingham Vasculitis Activity Score (BVAS) Dim system necrotizinig vasculitis (1994)
LUQMANI, R.A., BACON, P.A., MOOTS, R.J., JANSSEN, B.A., PALL, A., EMERY, P., ...
The continuing morbidity of patients with vasculitis despite the improved prognosis with aggressive therapy, underlines the need for accurate disease assessment We have devised a clinical index of...
Classical versus non-renal Wegener's granulomatosis (1994)
LUQMANI, R.A., BACON, P.A., BEAMAN, M., SCOTT, D.G.I., EMERY, P., LEE, S.J., ...
We investigated whether ‘limited’ or lsquo;non-renal’ Wegener's granulomatosis (WG) differs from classical or ‘renal’ WG. Renal WG is characterized by necrotizing granulomatosis of the...
SALMON, M., WORDSWORTH, P., EMERY, P., TUNN, E., BACON, P. A., BELL, J. I.
RA is associated with a group of class II DR β alleles, which share a conserved sequence in the third allelic hypervariable region (3AHVR). These include the DR4 subtypes Dw4, Dw14 and Dw15, and...
Relapses in patients with a systemic vasculitis (1993)
GORDON, M., LUQMANI, R.A., ADU, D., GREAVES, I., RICHARDS, N., MICHAEL, J., ...
Treatment with cyclophosphamide and steroids has greatly improved survival in patients with systemic necrotizing vasculitis but does not always provide a complete cure. There are as yet few data on...
THE GENETIC BASIS OF RESPONSES TO DRUGS--A RHEUMATOLOGICAL PERSPECTIVE (1993)
The wide individual variations seen in all metabolic pathways which have been examined largely explain differences in drug dose response and toxicity. In some cases, distinct sub-sets occur where the...
PELVIC INSUFFICIENCY FRACTURES IN RHEUMATOID ARTHRITIS (1993)
PEH, W. C. G., GOUGH, A. K. S., SHEERAN, T., EVANS, N. S., EMERY, P.
The occurrence of pelvic insufficiency fractures in patients with rheumatoid arthritis has not previously been well emphasized. These fractures are difficult to detect clinically and appropriate...
GLOMERULONEPHRITIS IN RHEUMATOID ARTHRITIS (1993)
ADU, D., BERISA, F., HOWIE, A. J., EMERY, P., BACON, P. A., McCONKEY, B., ...
We present data on 10 patients with RA who developed glomerulonephritis which was not related to gold or penicillamine therapy. Although two of these patients had received gold this had been...
GENETIC FACTORS INFLUENCING THE OUTCOME OF EARLY ARTHRITIS-THE ROLE OF SULPHOXIDATION STATUS (1992)
EMERY, P., BRADLEY, H., ARTHUR, V., TUNN, E., WARING, R.
A minority of individuals have an impaired ability to oxidize sulphur. An increased prevalence of this poor S-oxidation capacity has been observed in patients with established rheumatoid arthritis...
VENOSTASIS, SUBCLINICAL VASCULITIS AND VON WILLEBRAND FACTOR ANTIGEN (1991)
BLANN, A. D., WAINWRIGHT, A. C., SHEERAN, T. P., EMERY, P.
Von Willebrand factor antigen (VW FAg) has been used as a marker for vasculitis and raised levels have been shown to correlate with active disease. The use of VW FAg levels in the diagnosis of...
SERONEGATIVE AND SEROPOSITIVE RHEUMATOID ARTHRITIS: SIMILAR DISEASES (1987)
PANAYI, G. S., CELINSKA, EWA, EMERY, P., GRIFFIN, JANE, WELSH, K. I., GRAHAME, R., ...
A case control study of 50 rheumatoid factor positive (RA+) and 50 rheumatoid factor negative (RA−) patients with rheumatoid arthritis has been carried out. As expected, the RA+ group has...
GIBSON, T., EMERY, P., ARMSTRONG, R. D., CRISP, A. J., PANAYI, G. S.
Seventy-two patients with relatively early but progressive rheumatoid arthritis were treated with chloroquine sulphate, D-penicillamine or a combination of both drugs over 1 year. Chloroquine...
LYMPHOCYTAPHERESIS-A FEASIBLE TREATMENT FOR RHEUMATOID ARTHRITIS (1986)
EMERY, P., SMITH, G. N., PANAYI, G. S.
A short three-treatment out-patient course of lymphocytapheresis (LA) was compared with a standard six-treatment regimen in a group of rheumatoid arthritis patients pre-selected for poor...
A DOUBLE-BLIND STUDY OF THE SIMPLE ANALGESIC NEFOPAM IN RHEUMATOID ARTHRITIS (1986)
The role of pure analgesics in the management of rheumatoid arthritis (RA) remains uncertain. In a double-blind cross-over study of 27 patients, nefopam was a more effective analgesic than placebo...
Bulletin de la Société Lorraine des Sciences, Septembre-Novembre 1962 (1962)
BALDO, S., BENE, R., BOISTELLE, R., CHARRUIT, P., EMERY, P., ...
RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom.
Emery, P, Durand, B, Mach, B, Reith, W
Until recently, the RFX family of DNA binding proteins consisted exclusively of four mammalian members (RFX1-RFX4) characterized by a novel highly conserved DNA binding domain. Strong conservation of...
DNA binding properties of a chemically synthesized DNA binding domain of hRFX1.
Cornille, F, Emery, P, Schüler, W, Lenoir, C, Mach, B, Roques, B P, ...
The RFX DNA binding domain (DBD) is a novel highly conserved motif belonging to a large number of dimeric DNA binding proteins which have diverse regulatory functions in eukaryotic organisms, ranging...
A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity.
Emery, P, Strubin, M, Hofmann, K, Bucher, P, Mach, B, Reith, W
The RFX DNA binding domain is a novel motif that has been conserved in a growing number of dimeric DNA-binding proteins, having diverse regulatory functions, in eukaryotic organisms ranging from...
Siegrist, C A, Durand, B, Emery, P, David, E, Hearing, P, Mach, B, ...
Hepatitis B virus gene expression is to a large extent under the control of enhancer I (EnhI). The activity of EnhI is strictly dependent on the enhancer factor C (EF-C) site, an inverted repeat that...
Inhibition of T cell apoptosis in the rheumatoid synovium.
Salmon, M, Scheel-Toellner, D, Huissoon, A P, Pilling, D, Shamsadeen, N, Hyde, H, ...
Synovial T cells in rheumatoid arthritis are highly differentiated and express a phenotype suggesting susceptibility to apoptosis (CD45RB dull, CD45RO bright, Bcl-2 low, Bax high, Fas high). However,...
RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency.
Durand, B, Sperisen, P, Emery, P, Barras, E, Zufferey, M, Mach, B, ...
Major Histocompatibility Complex class II (MHC-II) deficiency is a disease of gene regulation that provides a unique opportunity for the genetic dissection of the molecular mechanisms controlling...
RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom.
Emery, P, Durand, B, Mach, B, Reith, W
Until recently, the RFX family of DNA binding proteins consisted exclusively of four mammalian members (RFX1-RFX4) characterized by a novel highly conserved DNA binding domain. Strong conservation of...
DNA binding properties of a chemically synthesized DNA binding domain of hRFX1.
Cornille, F, Emery, P, Schüler, W, Lenoir, C, Mach, B, Roques, B P, ...
The RFX DNA binding domain (DBD) is a novel highly conserved motif belonging to a large number of dimeric DNA binding proteins which have diverse regulatory functions in eukaryotic organisms, ranging...
A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity.
Emery, P, Strubin, M, Hofmann, K, Bucher, P, Mach, B, Reith, W
The RFX DNA binding domain is a novel motif that has been conserved in a growing number of dimeric DNA-binding proteins, having diverse regulatory functions, in eukaryotic organisms ranging from...
Siegrist, C A, Durand, B, Emery, P, David, E, Hearing, P, Mach, B, ...
Hepatitis B virus gene expression is to a large extent under the control of enhancer I (EnhI). The activity of EnhI is strictly dependent on the enhancer factor C (EF-C) site, an inverted repeat that...
Inhibition of T cell apoptosis in the rheumatoid synovium.
Salmon, M, Scheel-Toellner, D, Huissoon, A P, Pilling, D, Shamsadeen, N, Hyde, H, ...
Synovial T cells in rheumatoid arthritis are highly differentiated and express a phenotype suggesting susceptibility to apoptosis (CD45RB dull, CD45RO bright, Bcl-2 low, Bax high, Fas high). However,...
RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency.
Durand, B, Sperisen, P, Emery, P, Barras, E, Zufferey, M, Mach, B, ...
Major Histocompatibility Complex class II (MHC-II) deficiency is a disease of gene regulation that provides a unique opportunity for the genetic dissection of the molecular mechanisms controlling...
Emery, P, Panayi, G, Symmons, D, Brown, G
The presence of anergy and its relationship to malnutrition was investigated in patients with rheumatoid arthritis (RA) and in controls. A generalised reduction in delayed cutaneous hypersensitivity...
Emery, P, Lopez, A F, Burns, G F, Vadas, M A
The level of expression of surface antigens was studied on neutrophils from paired samples of blood and synovial fluid of patients with rheumatoid arthritis (RA). By measuring the immunofluorescence...
Associations between HLA and antibodies to collagen in rheumatoid arthritis.
Rowley, M J, Tait, B, Doran, T, Emery, P, Mackay, I R
Associations between HLA types and serum antibodies to native and denatured type II collagen were sought in 105 patients with rheumatoid arthritis (RA). Antibodies were measured using a solid phase...
Comparison of clinical, radionuclide, and radiographic features of osteoarthritis of the hands.
Macfarlane, D G, Buckland-Wright, J C, Emery, P, Fogelman, I, Clark, B, Lynch, J
Simultaneous clinical, scintigraphic, and macroradiographic assessments were carried out on 32 patients with hand osteoarthritis and the results at entry and one year reported. The presence and...
Emery, P, Bradley, H, Gough, A, Arthur, V, Jubb, R, Waring, R
A minority of normal subjects have an impaired ability to oxidise sulphur, which is associated with an increased risk of side effects when they receive sulphur containing drugs. In 114 patients with...
Blann, A D, Wainwright, A C, Emery, P
Serum levels of von Willebrand factor antigen (as an index of damage to the endothelium) and tissue antinuclear antibodies and antibodies to SSA (Ro) (which have been associated with vasculitis) and...
Antibodies to protein P in systemic lupus erythematosus.
Teh, L S, Bedwell, A E, Isenberg, D A, Gordon, C, Emery, P, Charles, P J, ...
A synthetic peptide was used to develop an enzyme linked immunosorbent assay (ELISA) to detect antibodies to the ribosomal proteins P0, P1, and P2. Significantly increased levels of IgG antibodies to...
Assessment of lupus: where are we now?
Decisions about treatment for patients with SLE are based on numerous criteria, including the rate of change of clinical features and disease markers (especially antibodies to dsDNA and markers of...
Chronic shoulder pain is a common and disabling symptom in patients with rheumatoid arthritis (RA). It has been previously shown that a suprascapular nerve block (SSNB) using the standard mixture of...
Gough, A K, Peel, N F, Eastell, R, Holder, R L, Lilley, J, Emery, P
OBJECTIVE--To establish if urinary excretion rates of the collagen crosslinks pyridinoline and deoxypyridinoline, which are known to be elevated in established rheumatoid arthritis (RA), are useful...
OBJECTIVE: To study the effect of intraarticular (IA) sympathetic blockade for the relief of resistant shoulder pain. METHODS: Eighteen patients with shoulder pain resistant to conventional treatment...
Gout with apparent resistance to allopurinol
Gibson, T., Simmonds, H. A., Rodgers, A. V., Huston, G. J., Webster, D. R., Munro, J., ...
Veale, D, Reece, R, Parsons, W, Radjenovic, A, O'Connor, P, Orgles, C, ...
OBJECTIVES—CD4+ T cells sustain the chronic synovial inflammatory response in rheumatoid arthritis (RA). SB-210396/CE 9.1 is an anti-CD4 monoclonal antibody that has documented efficacy in RA when...
Synovial biopsy in arthritis research: five years of concerted European collaboration
Bresnihan, B., Tak, P. P., Emery, P., Klareskog, L., Breedveld, F.
Subclinical vasculitis in polymyalgia rheumatica
Marzo-Ortega, H, McGonagle, D, O'Connor, P, Pease, C, Emery, P
Albers, J, Paimela, L, Kurki, P, Eberhardt, K, Emery, P, ...
OBJECTIVE—To compare four different inception cohorts of patients with early rheumatoid arthritis (RA) with respect to treatment strategies, disease activity, and outcome during a five year follow...
Binks, M, Passweg, J, Furst, D, McSweeney, P, Sullivan, K, Besenthal, C, ...
BACKGROUND—Systemic sclerosis (SSc, scleroderma) in either its diffuse or limited skin forms has a high mortality when vital organs are affected. No treatment has been shown to influence the...
McGonagle, D, Reade, S, Marzo-Ortega, H, Gibbon, W, O'Connor, P, Morgan, A, ...
The pathogenesis of human immunodeficiency virus (HIV) associated spondyloarthropathy (SpA) is poorly understood. In this case report a patient is described with severe HIV associated reactive...
Emery, P, Breedveld, F, Dougados, M, Kalden, J, Schiff, M, Smolen, J
Objective: To develop a referral recommendation that may serve as a clinical guide for primary care doctors, enabling them to identify patients with suspected RA during the early inflammatory stages.
Young, A, Dixey, J, Kulinskaya, E, Cox, N, Davies, P, Devlin, J, ...
Objectives: To assess the occurrence and prognostic factors for the ability to maintain paid work in patients with rheumatoid arthritis (RA).
Histological assessment of the early enthesitis lesion in spondyloarthropathy
McGonagle, D, Marzo-Ortega, H, O'Connor, P, Gibbon, W, Hawkey, P, Henshaw, K, ...
Methods: Clinically evident acute enthesopathy was confirmed by magnetic resonance imaging and ultrasonography in four cases of plantar fasciitis and one case of patellar tendon enthesitis....
Bone mineral density improvement in spondyloarthropathy after treatment with etanercept
Marzo-Ortega, H, McGonagle, D, Haugeberg, G, Green, M, Stewart, S, Emery, P
Rau, R, Breedveld, F, Kalden, J, Malaise, M, ...
Objectives: To evaluate efficacy, dose response, safety, and tolerability of adalimumab (D2E7) in disease modifying antirheumatic drug (DMARD) refractory patients with longstanding, active rheumatoid...
Overexpression of transcripts containing LINE-1 in the synovia of patients with rheumatoid arthritis
Ali, M, Veale, D, Reece, R, Quinn, M, Henshaw, K, Zanders, E, ...
Methods: Synovial biopsy specimens were obtained by needle arthroscopy from the knees of 10 patients with either RA or ReA. RNA was isolated from the biopsy specimens and cDNA synthesised for...
Development of the PsAQoL: a quality of life instrument specific to psoriatic arthritis
McKenna, S, Doward, L, Whalley, D, Tennant, A, Emery, P, Veale, D
Background: Patient reported outcome measures used in studies of psoriatic arthritis (PsA) have been found to be inadequate for determining the impact of the disease from the patient's perspective.
Infliximab in active early rheumatoid arthritis
Breedveld, F, Emery, P, Keystone, E, Patel, K, Furst, D, Kalden, J, ...
Objective: To examine the impact of the combination of infliximab plus methotrexate (MTX) on the progression of structural damage in patients with early rheumatoid arthritis (RA).
Access to disease modifying treatments for rheumatoid arthritis patients
FURST, D, BREEDVELD, F, BURMESTER, G, CROFFORD, L, EMERY, P, FELDMAN, M, ...
Staging of patients with ankylosing spondylitis: a preliminary proposal
Braun, J, Dougados, M, Emery, P, Khan, M, Sieper, J, ...
Patients with ankylosing spondylitis (AS) are characterised by a wide range of clinical presentations, radiographic profiles, and outcomes, which are not well differentiated by current diagnostic and...
Should oligoarthritis be reclassified? Ultrasound reveals a high prevalence of subclinical disease
Wakefield, R, Green, M, Marzo-Ortega, H, Conaghan, P, Gibbon, W, McGonagle, D, ...
Objective: To determine the prevalence of subclinical synovitis using ultrasound (US) imaging of both painful and asymptomatic joints, in patients with early (
Yee, C, Gordon, C, Dostal, C, Petera, P, Dadoniene, J, Griffiths, B, ...
Objective: To compare the efficacy and side effects of intermittent pulse cyclophosphamide plus methylprednisolone with continuous oral cyclophosphamide plus prednisolone, followed by azathioprine,...
Atkins, C, Malaise, M, Sany, J, Russell, A, ...
Objective: To evaluate the efficacy and safety of monotherapy with adalimumab in patients with RA for whom previous DMARD treatment has failed.
Ultrasound detection of knee patellar enthesitis
Wakefield, R, McGonagle, D, Tan, A, Evangelisto, A, Emery, P, Kamel, M, ...
Emery, P., Salmon, M., Bradley, H., Wordsworth, P., Tunn, E., Bacon, P. A., ...
OBJECTIVE--To determine whether genetic factors associated with established rheumatoid arthritis could, in combination with rheumatoid factor, predict the development of radiological erosions in...
Blount, S, Griffiths, H, Emery, P, Lunec, J
During the development of an ELISA to measure anti-DNA antibodies in systemic lupus erythematosus (SLE) sera, native dsDNA was found not to be the most appropriate antigen to use in ELISA assays for...
Interleukin-2 reverses deficient cell-mediated immune responses in rheumatoid arthritis.
Emery, P, Panayi, G S, Nouri, A M
The depressed cell-mediated immunity in rheumatoid arthritis was investigated in vivo by cutaneous hypersensitivity responses to seven antigens including tuberculin PPD, and in vitro by lymphocyte...
Interleukin 2 inhibitor in synovial fluid.
Emery, P, Gentry, K C, Kelso, A, Mackay, I R
Since evidence for the presence of IL-2 activity in rheumatoid synovial fluid is conflicting, we have assayed IL-2 activity in synovial fluid from patients with rheumatoid arthritis (RA) and other...
Urinary IL-6: a marker for mesangial proliferative glomerulonephritis?
Gordon, C, Richards, N, Howie, A J, Richardson, K, Michael, J, Adu, D, ...
A prospective study of plasma and urinary interleukin-6 (IL-6) levels was performed in 54 patients undergoing renal biopsy to determine whether detectable urinary IL-6 was a reliable marker for...
Haugeberg, G, Griffiths, B, Sokoll, K, Emery, P
Objective: To examine the influence of intravenous pulsed methylprednisolone (MP) on bone mass.
Farge, D, Passweg, J, Van Laar, J M, Marjanovic, Z, Besenthal, C, Finke, J, ...
Objective: To analyse the durability of the responses after haematopoietic stem cell transplantation (HSCT) for severe systemic sclerosis (SSc) and determine whether the high transplant related...
Milz, S, Tischer, T, Buettner, A, Schieker, M, Maier, M, Redman, S, ...
Objectives: To improve the understanding of epicondylitis by describing the normal structure and composition of the entheses associated with the medial and lateral epicondyles and their...
Tan, A, Marzo-Ortega, H, O'Connor, P, Fraser, A, Emery, P, McGonagle, D
Objective: To determine the efficacy of anakinra, an interleukin 1 receptor antagonist in active ankylosing spondylitis (AS), and to investigate the effect of anakinra treatment on spinal...
True infliximab resistance in rheumatoid arthritis: a role for lymphotoxin α?
Buch, M, Conaghan, P, Quinn, M, Bingham, S, Veale, D, Emery, P
Case report: A patient with RA resistant to repeated high dose infliximab infusions and intra-articular infliximab into an inflamed knee is described. No beneficial clinical effect was observed....
Furst, D, Breedveld, F, Kalden, J, Smolen, J, Burmester, G, Bijlsma, J, ...
Outcomes of a multicentre randomised clinical trial of etanercept to treat ankylosing spondylitis
Calin, A, Dijkmans, B, Emery, P, Hakala, M, Kalden, J, Leirisalo-Repo, M, ...
Objective: A double blind, randomised, placebo controlled study to evaluate the safety and efficacy of etanercept to treat adult patients with ankylosing spondylitis (AS).
Benjamin, M, Redman, S, Milz, S, Buttner, A, Amin, A, Moriggl, B, ...
Objectives: To describe the distribution of adipose tissue within and adjacent to entheses in order to assess its functional significance at attachment sites.
Dougados, M, Emery, P, Lemmel, E, Zerbini, C, Brin, S, Van Riel, P
Objective: To evaluate the efficacy and safety of adding sulfasalazine to leflunomide treatment compared with switching to sulfasalazine alone in patients with RA with an inadequate response to...
The EULAR–OMERACT rheumatoid arthritis MRI reference image atlas: the wrist joint
Ejbjerg, B, McQueen, F, Lassere, M, Haavardsholm, E, Conaghan, P, O'Connor, P, ...
An introduction to the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas
Ostergaard, M, Edmonds, J, McQueen, F, Peterfy, C, Lassere, M, Ejbjerg, B, ...
The EULAR–OMERACT rheumatoid arthritis MRI reference image atlas: the metacarpophalangeal joints
Conaghan, P, Bird, P, Ejbjerg, B, O'Connor, P, Peterfy, C, McQueen, F, ...
The development of the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas
Bird, P, Conaghan, P, Ejbjerg, B, McQueen, F, Lassere, M, Peterfy, C, ...
Pitfalls in scoring MR images of rheumatoid arthritis wrist and metacarpophalangeal joints
McQueen, F, Ostergaard, M, Peterfy, C, Lassere, M, Ejbjerg, B, Bird, P, ...
Toumi, H, Higashiyama, I, Suzuki, D, Kumai, T, Bydder, G, McGonagle, D, ...
Proximal patellar tendinopathy occurs as an overuse injury in sport and is also characteristic of ankylosing spondylitis patients. It particularly affects the posteromedial part of the patellar...
Lawson, C, Donaldson, I, Bowman, S, Shefta, J, Morgan, A, Gough, A, ...
Methods: Genomic DNA was extracted from blood samples from patients fulfilling the modified European criteria for PSS (n = 61). Healthy control blood samples were obtained from the Blood Transfusion...
Minocycline induced autoimmune hepatitis and systemic lupus erythematosus-like syndrome.
Gough, A., Chapman, S., Wagstaff, K., Emery, P., Elias, E.
Monocycline is the most widely prescribed systemic antibiotic for acne largely because it needs to be given only once or twice a day and seems not to induce resistance. Up to April 1994 11 cases of...
Fraser, A, Westhovens, R, Karim, Z, Wakefield, R, Gerards, A, ...
Objectives: To evaluate the safety and efficacy of adding ciclosporin A (CSA) to the treatment of patients with psoriatic arthritis (PsA) demonstrating an incomplete response to methotrexate (MTX)...
Rhodes, L, Conaghan, P, Radjenovic, A, Grainger, A, Emery, P, McGonagle, D
Objective: To determine if the distribution of synovitis is the same in osteoarthritis (OA) using sensitive measures of inflammation derived from dynamic, contrast enhanced magnetic resonance imaging...
Antochi, R, Stavrakaki, C, Emery, P
People with developmental disabilities are at considerable risk for the development of comorbid psychiatric conditions. Psychopharmacological treatments may have a crucial role in a multidisciplinary...
Electrical cardioversion for persistent atrial fibrillation after treatment of thyrotoxicosis
A review of 22 patients with atrial fibrillation after the treatment of thyrotoxicosis, who underwent elective electrical cardioversion, showed that only 45% were still in sinus rhythm at 2 years and...
HLA-DR4 and career prospects in rheumatology: is there a link?
Gough, A., Faint, J., Salmon, M., Bacon, P., Emery, P.
OBJECTIVE--To determine whether HLA type is associated with career progress in rheumatology. DESIGN--Comparison of HLA type after HLA analysis of samples of venous blood. SETTING--Department of...
Marzo-Ortega, H, McGonagle, D, Jarrett, S, Haugeberg, G, Hensor, E, O'Connor, P, ...
Objective: To examine the efficacy and safety of infliximab combined with methotrexate compared with methotrexate alone in the treatment of ankylosing spondylitis (AS) using MRI and DXA to monitor...
Furst, D, Breedveld, F, Kalden, J, Smolen, J, Burmester, G, Bijlsma, J, ...
D'Agostino, M, Conaghan, P, Le Bars, M, Baron, G, Grassi, W, Martin-Mola, E, ...
Objectives: To assess the prevalence of inflammation in subjects with chronic painful knee osteoarthritis (OA), as determined by the presence of synovitis or joint effusion at ultrasonography (US);...
Conaghan, P, D'Agostino, M, Ravaud, P, Baron, G, Le Bars, M, Grassi, W, ...
Background: Synovial inflammation (as defined by hypertrophy and effusion) is common in osteoarthritis (OA) and may be important in both pain and structural progression.
Potter, C, Hyrich, K L, Tracey, A, Lunt, M, Plant, D, Symmons, D P M, ...
Tan, A L, Toumi, H, Benjamin, M, Grainger, A J, Tanner, S F, Emery, P, ...