Bertolini, F., Mingrone, W., Alietti, A., Ferrucci, P. F., Cocorocchio, E., Peccatori, F., ...
Background: Thalidomide, as a single agent, has been recently found to induce a clinical response in one third of refractory or relapsed myeloma patients. Although it has been reported that...
Ruthardt, M, Testa, U, Nervi, C, Ferrucci, P F, Grignani, F, Puccetti, E, ...
Fusion proteins involving the retinoic acid receptor alpha (RAR alpha) and the PML or PLZF nuclear protein are the genetic markers of acute promyelocytic leukemias (APLs). APLs with the PML-RAR alpha...
Grignani, F, Testa, U, Rogaia, D, Ferrucci, P F, Samoggia, P, Pinto, A, ...
The block of terminal differentiation is a prominent feature of acute promyelocytic leukemia (APL) and its release by retinoic acid correlates with disease remission. Expression of the APL-specific...
Ruthardt, M, Testa, U, Nervi, C, Ferrucci, P F, Grignani, F, Puccetti, E, ...
Fusion proteins involving the retinoic acid receptor alpha (RAR alpha) and the PML or PLZF nuclear protein are the genetic markers of acute promyelocytic leukemias (APLs). APLs with the PML-RAR alpha...
Grignani, F, Testa, U, Rogaia, D, Ferrucci, P F, Samoggia, P, Pinto, A, ...
The block of terminal differentiation is a prominent feature of acute promyelocytic leukemia (APL) and its release by retinoic acid correlates with disease remission. Expression of the APL-specific...
Angiogenesis in myelodysplastic syndromes
Pruneri, G, Bertolini, F, Soligo, D, Carboni, N, Cortelezzi, A, Ferrucci, P F, ...
It is now well established that solid tumour growth depends on angiogenesis. However, less is known about the generation of new vessels in haematological malignancies and, in particular, in...
Corsini, C, Ghielmini, M, Mancuso, P, Tealdo, F, Paolucci, M, Zucchetti, M, ...
We evaluated in vitro the toxicity of idarubicin and its active metabolite idarubicinol on haematopoietic progenitors, using human umbilical cord blood and peripheral blood progenitors to obtain...