P. F. Ferrucci

Publication List Details

Period

2001 - 2005

Number

9

Co-Authors

Thalidomide in multiple myeloma, myelodysplastic syndromes and histiocytosis. Analysis of clinical results and of surrogate angiogenesis markers (2001)

Bertolini, F., Mingrone, W., Alietti, A., Ferrucci, P. F., Cocorocchio, E., Peccatori, F., ...

Background: Thalidomide, as a single agent, has been recently found to induce a clinical response in one third of refractory or relapsed myeloma patients. Although it has been reported that...

Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

Ruthardt, M, Testa, U, Nervi, C, Ferrucci, P F, Grignani, F, Puccetti, E, ...

Fusion proteins involving the retinoic acid receptor alpha (RAR alpha) and the PML or PLZF nuclear protein are the genetic markers of acute promyelocytic leukemias (APLs). APLs with the PML-RAR alpha...

Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding domains.

Grignani, F, Testa, U, Rogaia, D, Ferrucci, P F, Samoggia, P, Pinto, A, ...

The block of terminal differentiation is a prominent feature of acute promyelocytic leukemia (APL) and its release by retinoic acid correlates with disease remission. Expression of the APL-specific...

Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

Ruthardt, M, Testa, U, Nervi, C, Ferrucci, P F, Grignani, F, Puccetti, E, ...

Fusion proteins involving the retinoic acid receptor alpha (RAR alpha) and the PML or PLZF nuclear protein are the genetic markers of acute promyelocytic leukemias (APLs). APLs with the PML-RAR alpha...

Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding domains.

Grignani, F, Testa, U, Rogaia, D, Ferrucci, P F, Samoggia, P, Pinto, A, ...

The block of terminal differentiation is a prominent feature of acute promyelocytic leukemia (APL) and its release by retinoic acid correlates with disease remission. Expression of the APL-specific...

Angiogenesis in myelodysplastic syndromes

Pruneri, G, Bertolini, F, Soligo, D, Carboni, N, Cortelezzi, A, Ferrucci, P F, ...

It is now well established that solid tumour growth depends on angiogenesis. However, less is known about the generation of new vessels in haematological malignancies and, in particular, in...

Idarubicinol myelotoxicity: a comparison of in vitro data with clinical outcome in patients treated with high-dose idarubicin

Corsini, C, Ghielmini, M, Mancuso, P, Tealdo, F, Paolucci, M, Zucchetti, M, ...

We evaluated in vitro the toxicity of idarubicin and its active metabolite idarubicinol on haematopoietic progenitors, using human umbilical cord blood and peripheral blood progenitors to obtain...