Covey-Crump, S J, Schofield, P F, Stretton, I C, Daymond, M R, Knight, K S
Acta Mat (in press 2003)
XPEEM valence state imaging of mineral micro-intergrowths with a spatial resolution of 100 nm (2003)
Smith, A. D., Schofield, P. F., Scholl, A., Pattrick, R.A.D., Bridges, J.C.
The crystal chemistry and textural relationships of minerals hold a vast amount of information relating to the formation, history and stability of natural materials. The application of soft X-ray...
Chemistry and valency spectra of Chromite in SNC meteorites (2002)
Bridges, John, Schofield, P. F., Smith, A. D., Scholl, A., Grady, Monica
Shergottite chromite core mantle sources were Al-poor, Fe-rich, low Fe^{3+}/Fe^{2+}, fO_{2} 1 to 4 units
Mineral Sciences, Earth Sciences, Environmental and Cultural Heritage (4.7) (2002)
Rinaldi, R, Artioli, G, Dove, M T, Schaefer, W, Schofield, P F
ESS Project, Vol II. New Science and Technology for the 21st Century. ESS Council 4-89/4-108
Cultural Heritage: Artefacts and Materials (6.5) (2002)
Artioli, G, Kockelmann, W, Magerl, A, Mezei, F, Rinaldi, R, Schaefer, W, ...
ESS Project, Vol II. New Science and Technology for the 21st Century. ESS Council 6-47/6-54
Accurate quantification of the modal mineralogy of rocks when image analysis is difficult (2002)
Schofield, P F, Knight, K S, Covey-Crump, S J, Cressey, G, Stretton, I C
The partitioning of strain during rock deformation (2001)
Stretton, I C, Covey-Crump, S J, Schofield, P F, Daymond, M R, Knight, K S
Rinaldi, R, Artioli, G, Dove, M T, Shaefer, W, Schofield, P F, Winkler, B
In ESS-SAC/ENSA Report 1/01 on Scientific Trends in Condensed Matter Research and Instrumentation Opprotunities at ESS, p91 (2001)
A STUDY OF THE ARTERIAL CLEARANCE OF XENON 133 IN MAN (1965)
ISBISTER, W. H., SCHOFIELD, P. F., TORRANCE, H. B.
Arterial xenon 133 concentrations have been measured after inhalation of the isotope in anaesthetized and conscious human patients. The anaesthetized patients were ventilated by either a mechanical...
Primary squamous cell carcinoma of the terminal ileum.
Platt, C C, Haboubi, N Y, Schofield, P F
A case of squamous cell carcinoma of the terminal ileum with no underlying duplication or inflammatory disorder is described. The neoplasm seemed to have originated from the surface epithelium,...
Indications for and results of operation in inflammatory bowel disease.
Of 363 patients with inflammatory bowel disease presenting between 1972 and 1983, 166 required definitive operation. A classification by histological type distinguishes Crohn's disease (CD) from...
Are we using the correct dose of metronidazole in colorectal surgery?
Hobbiss, J H, Carr, N D, Schofield, P F
In a series of 20 patients undergoing elective colorectal surgery, 10 received an infusion of metronidazole 500 mg and 10 an infusion of 1500 mg commencing at the induction of anaesthesia. The...
Abdominal lymphoma--the place for surgery.
Baildam, A D, Williams, G T, Schofield, P F
Gastrointestinal lymphoma (GIL) is rare but may be cured by surgery and chemotherapy. Because symptoms frequently mimic common abdominal conditions, presentation is often to a surgeon. Fifty-five...
Haboubi, N Y, Clark, P, Kaftan, S M, Schofield, P F
The prognosis of colorectal carcinoma relies heavily on pathological staging which includes the metastatic state of lymph nodes. Colorectal resectates from 47 patients (41 with colorectal carcinoma...
Effect of anorectal eversion on long-term clinical outcome of restorative proctocolectomy.
DeFriend, D J, Mughal, M, Grace, R H, Schofield, P F
Eversion of the rectum during restorative proctocolectomy with stapled ileal pouch-anal anastomosis (IPAA) remains a controversial surgical manoeuvre because of concern that it may impair anal...
Management of perianal Crohn's disease.
Symptomatic anal disease (excluding skin tags) was observed in 49 out of 151 successive patients treated for Crohn's disease. Two main types of anal disease were encountered: anal ulceration (23...
Bowel disease after radiotherapy.
Schofield, P F, Holden, D, Carr, N D
The clinical presentation, operative findings and outcome in 40 patients who required surgery for bowel disease after radiotherapy are presented. The type of presentation varied according to the time...
Diagnosis and management of psoas abscess in Crohn's disease.
Four patients with Crohn's disease complicated by psoas abscess are described. These patients did not have general or abdominal signs of sepsis but they all showed wasting of the right quadriceps...
Computed tomographic scanning in rectal carcinoma.
Zheng, G, Johnson, R J, Eddleston, B, James, R D, Schofield, P F
Computed tomographic (CT) scanning has been used to assess the extent of local spread in 85 patients with rectal carcinoma. In 37 patients with carcinoma of the rectum who were scanned before...
Lambert, M E, Schofield, P F, Ironside, A G, Mandal, B K
Eleven consecutive patients with diarrhoea from whose stools campylobacter were isolated were investigated by sigmoidoscopy and rectal biopsy. Eight had definite proctitis, and in seven biopsy...
Role of autologous lymphocyte cytotoxicity in colonic neoplasia.
Gallagher, P, Vose, B M, Moore, M, Schofield, P F
The T-lymphocyte mediated killing of autologous carcinoma colon cells was investigated. There was no change in the incidence of activity with advanced disease, age, or nutritional status of the...
Microvascular studies in human radiation bowel disease.
Carr, N D, Pullen, B R, Hasleton, P S, Schofield, P F
The microvasculature was investigated in the normal bowel (n = 43 patients) and in radiation bowel disease (n = 18 patients). Tissue samples obtained from postoperative colectomy specimens in which...
Jackson, C W, Haboubi, N Y, Whorwell, P J, Schofield, P F
A case of gold associated enterocolitis is described. A review of all 27 previously reported cases revealed that the syndrome induced has common characteristics. The reaction occurs within three...
Microvascular studies in non-specific inflammatory bowel disease.
Carr, N D, Pullan, B R, Schofield, P F
The microvasculature was investigated in the normal bowel and in ulcerative colitis and Crohn's disease. Tissue samples from postoperative colectomy specimens in which the microvasculature had been...
Leucocytotoxicity in malignant and non-malignant colonic diseases.
Vose, B M, Moore, M, Schofield, P F, Dymock, I W
The survival of cells from five different cultures of allogeneic malignant colonic carcinoma, two from normal adult colonic epithelium and eight from foetal colonic epithelium in the presence of...
Toxic dilatation and perforation in inflammatory bowel disease.
The diagnosis and management of dilatation of the colon and free intestinal perforation in inflammatory or infective bowel disease are reviewed with reference to 32 cases seen during an 8-year...
Schofield, P. F., Hulton, N. R., Baildam, A. D.
In a prospective study of 100 patients presenting with acute right hypochondrial pain and diagnosed clinically by a qualified surgeon as having acute cholecystitis, we have shown that the diagnostic...
Ischaemic dilatation of the colon.
Carr, N. D., Wells, S., Haboubi, N. Y., Salem, R. J., Schofield, P. F.
The present paper describes the presentation and management of 9 patients who developed dilatation in the colon during the course of spontaneous ischaemic colitis. The length of history varied from...
Massive colonic haemorrhage--the case for right hemicolectomy.
Milewski, P. J., Schofield, P. F.
A total of 14 patients had operations for massive colonic haemorrhage. Of the seven who had a right hemicolectomy, four had the bleeding site localised, and three had only 'equivocal' indications of...
Inguinal hernia: medicolegal implications.
Repair of an inguinal hernia is one of the commonest operations undertaken by surgeons but the role of trauma in causing inguinal hernia is not well understood. This paper does not attempt to discuss...
Wilson, M. S., West, C. M., Wilson, G. D., Roberts, S. A., James, R. D., Schofield, P. F.
An assessment has been made of the reproducibility of measuring tumour proliferation using in vivo iododeoxyuridine (IUdR) labelling and flow cytometry. The variation that occurs between different...
Intra-tumoral heterogeneity of tumour potential doubling times (Tpot) in colorectal cancer.
Wilson, M. S., West, C. M., Wilson, G. D., Roberts, S. A., James, R. D., Schofield, P. F.
Intra-tumoural heterogeneity of proliferation has been assessed by taking multiple biopsies from 30 colorectal cancers. Following in vivo IUDR labelling, dual parameter flow cytometry was used to...
Prognostic significance of 5T4 oncofetal antigen expression in colorectal carcinoma.
Starzynska, T., Marsh, P. J., Schofield, P. F., Roberts, S. A., Myers, K. A., Stern, P. L.
The 5T4 oncofetal antigen is a 72 kDa glycoprotein defined by a monoclonal antibody raised against human placental trophoblast and is expressed in many different carcinomas but detected only at low...
Jones, D. J., Ghosh, A. K., Moore, M., Schofield, P. F.
Expression of c-myc was studied immunohistochemically in 100 colorectal carcinomas, using a monoclonal antibody, Myc 1-6E10, which is purported to recognize the oncoprotein (p62c-myc) in...
Specific and non-specific lymphocyte cytotoxicity in colon carcinoma.
Vose, B. M., Gallagher, P., Moore, M., Schofield, P. F.
The cytotoxic activity of peripheral-blood (PBL), lymph-node (LNC) and tumour-infiltrating lymphocytes (TIL) from 47 patients undergoing surgery for colon carcinoma (Duke's Stage A, 1 patient; B, 24;...
Robson, H., Anderson, E., James, R. D., Schofield, P. F.
Members of the transforming growth factor beta (TGF-beta family, in particular TGF-beta 1, are some of the most potent inhibitory growth factors in a variety of cell types. Resistance to TGF-beta...