Lowe, Jennifer Louise, Rohl, Andrew, Gale, Julian, Parkinson, Gordon, Smith, P.G.
DSP is an important by-product of alumina production via the Bayer process. Under Western Australian processing conditions, the DSP has a sodalite-type structure that can incorporate anions within...
Lowe, Jennifer Louise, Rohl, Andrew, Gale, Julian, Parkinson, Gordon, Smith, P.G.
DSP is an important by-product of alumina production via the Bayer process. Under Western Australian processing conditions, the DSP has a sodalite-type structure that can incorporate anions within...
A guide for diagnostic evaluations (2006)
Peeling, R.W., Smith, P.G., Bossuyt, P.M.M.
Accurate diagnostic tests have a key role in patient management and the control of most infectious diseases. Unfortunately, in many developing countries, clinical care is often critically compromised...
A guide for diagnostic evaluations (2006)
Peeling, R.W., Smith, P.G., Bossuyt, P.M.M.
Accurate diagnostic tests have a key role in patient management and the control of most infectious diseases. Unfortunately, in many developing countries, clinical care is often critically compromised...
Evaluation of diagnostic tests for infectious diseases: general principles (2006)
Banoo, S., Bell, D., Bossuyt, P.M.M., Herring, A., Mobey, D., Poole, F., ...
Evaluation of diagnostic tests for infectious diseases: general principles (2006)
Banoo, S., Bell, D., Bossuyt, P.M.M., Herring, A., Mabey, D., Poole, F., ...
Lowe, Jennifer Louise, Rohl, Andrew, Gale, Julian, Parkinson, Gordon, Smith, P.G.
DSP is an important by-product of alumina production via the Bayer process. Under Western Australian processing conditions, the DSP has a sodalite-type structure that can incorporate anions within...
Dyer, M., Utili, S., Smith, P.G.
Paper concerned with diffusion and retardation of benzene and toulene vapours inside a low moisture layer of the unsaturated zone.
Herpesvirus saimiri-based vector biodistribution using noninvasive optical imaging (2005)
Smith, P.G., Oakley, F., Fernandez, M., Mann, D.A., Lemoine, N.R., Whitehouse, A.
Herpesvirus saimiri (HVS) is capable of infecting a range of human cell types with high efficiency and the viral genome persists as high copy number, circular, nonintegrated episomes which segregate...
Methodological Lessons Learned in the Horizontal Integration Simulation Effort (2005)
Sawyer, A. R., Meade, G. A., Leibrecht, B. C., Lozicki, R. J., Pitney, O. S., Smith, P. G., ...
This report documents the methodological lessons learned in conducting the Horizontal Integration (HI) Experiment using Advanced Distributed Simulation Technology (ADST). The experiment was conducted...
Smeeth, L., Cook, C., Fombonne, E., Heavey, L., Rodrigues, L. C., Smith, P. G., ...
Background: There has been concern that the incidence of autism and other pervasive developmental disorders (PDDs) is increasing. Previous studies have been smaller, restricted to autism (excluding...
MMR vaccination and pervasive developmental disorders: a case-control study (2004)
Smeeth, L., Cook, C., Fombonne, E., Heavey, L., Rodrigues, L. C., Smith, P. G., ...
Background: Concern that measles-mumps-rubella (MMR) vaccination might cause autism has led to a fall in vaccine coverage. We investigated whether MMR vaccination is associated with an increased risk...
Validation of the diagnosis of autism in general practitioner records (2004)
Fombonne, E., Heavey, L., Smeeth, L., Rodrigues, L. C., Cook, C., Smith, P. G., ...
Background: We report on the validity of the computerized diagnoses of autism in a large case-control study investigating the possible association between autism and the measles, mumps and rubella...
Introduction to Food Process Engineering (2003)
Contenido: Introducción a la ingeniería de procesos de los alimentos; Dimensiones, cantidades y unidades; Termodinámica y equilibrio; Materiales y balance de energía; Fundamentos de los procesos...
Overview of JET results (2003)
Pamela, J., Solano, E. R., Adams, J. M., Agarici, G., Agarici, M., Akhter, H., ...
Scientific and technical activities on JET focus on the issues likely to affect the ITER design and operation. Our understanding of the ITER reference mode of operation, the ELMy H-mode, has...
Sex ratio of nuclear industry employees' children. (2001)
Maconochie, N., Roman, E., Doyle, P., Davies, G., Smith, P.G., Beral, V.
Does preconceptional exposure to ionising radiation before conception affect the health of offspring? Some studies have suggested that radiation exposure might influence the sex ratio at birth,...
Risk Factors for Child Mortality in Northern Ghana: A Case-Control Study (1995)
BINKA, F N, MAUDE, G H, GYAPONG, M, ROSS, D A, SMITH, P G
Background. A population-based case-control study was carried out to investigate potential risk factors for post-neonatal and child mortality in northern Ghana where child survival rates are among...
TROXLER, T., STRATTON, J.R., SMITH, P.G., TOPP, M.R.
1. Work supported by the NSF (CHE-91-20767) and by the ACS-PRF (24816-AC6)
ROTATIONAL COHERENCE SPECTROSCOPY TO MEASURE STRUCTURES OF GAS PHASE MOLECULAR COMPLEXES (1993)
Smith, P.G., Troxler, T., Topp, M.R.
Author Institution: Department of Chemistry, University of Pennsylvania
FIELD EVALUATION OF MEASLES VACCINE EFFICACY IN MOZAMBIQUE (1990)
CUTTS, F. T., SMITH, P. G., COLOMBO, S., MANN, G., ASCHERIO, A., SOARES, A. C.
Monitoring measles vaccine efficacy is an important form of quality control in immunization programs. Retrospective cohort studies of vaccine efficacy were conducted in Mozambique with the aim of...
Calculation of Power for Matched Pair Studies when Randomization is by Group (1989)
SHIPLEY, M J, SMITH, P G, DRAMAIX, M
Shipley M J (Department of Epidemiology and Population Sciences, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK), Smith P G and Dramaix M. Calculation of power for matched pair...
Epidemiological methods to evaluate vaccine efficacy (1988)
The proper way to measure the protective efficacy of a new vaccine is in a randomised controlled trial. About 10 such trials have been conducted to assess the protection that BCG confers against...
VICTORA, C G, SMITH, P G, VAUGHAN, J P, NOBRE, L C, LOMBARD, C, TEIXEIRA, A M B, ...
In a population-based case-control study in the metropolitan areas of Porto Alegre and Pelotas in southern Brazil children dying in infancy from diarrhoea were compared to neighbourhood controls in...
SMITH, P G, RODRIGUES, L C, FINE, P E M
Smith P G (Department of Medical Statistics and Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK), Rodrigues L C and Fine P E M. Assessment of the protective efficacy...
The Design of Case-Control Studies: The Influence of Confounding and Interaction Effects (1984)
This paper considers quantitatively the extent to which the interaction or confounding effects of covariates may influence the design of case-control studies with particular reference to sample size...
A study into the diffusion of dissolved oxygen through activated sludge. (1981)
Thesis (Ph. D.)--University of Strathclyde, 1981.
A study of fluidized bed granulation. (1980)
Thesis (Ph. D.)--University of London, 1980.
New variant Creutzfeldt-Jakob disease is more common in Britain than elsewhere
Ironside, J W, Knight, R S G, Will, R G, Smith, P G, Cousens, S N
Mortality of workers at the Sellafield plant of British Nuclear Fuels.
The mortality of all 14,327 people who were known to have been employed at the Sellafield plant of British Nuclear Fuels at any time between the opening of the site in 1947 and 31 December 1975 was...
Mortality among patients with ankylosing spondylitis after a single treatment course with x rays.
Mortality was studied in 14 111 patients with ankylosing spondylitis given a single course of x-ray treatment during 1935-54. Mortality from all causes combined was 66% greater than that of members...
Increasing prevalence of diabetes mellitus in children.
Patterson, C C, Thorogood, M, Mann, J I, Smith, P G, Heasman, M A, Clarke, J A
Association between Atherosclerotic Diseases and Carboxyhaemoglobin Levels in Tobacco Smokers
Wald, Nicholas, Howard, Susannah, Smith, P. G., Kjeldsen, Knud
In a cross-sectional study carboxyhaemoglobin (COHb) levels in tobacco smokers were found to provide a better indication of a person's risk of having developed certain atherosclerotic diseases,...
Between 1970 and 1975, 108 patients who presented with advanced or recurrent Hodgkin's disease and were free of disease after six courses of chemotherapy with mustine, vinblastine, procarbazine, and...
Johnston, P. G. B., Hardisty, R. M., Kay, H. E. M., Smith, P. G.
Analysis of the remission induction phase in three Medical Research Council trials of treatment of acute lymphoblastic leukaemia has provided evidence of the adverse effect of the combination of...
Toghill, P. J., Smith, P. G., Benton, Patricia, Brown, R. C., Matthews, H. L.
Twenty patients are described in whom liver damage appeared to be directly related to the administration of methyldopa. Sixteen had hepatitic syndromes from which they recovered on stopping...
Ross, D A, Kirkwood, B R, Binka, F N, Arthur, P, Dollimore, N, Morris, S S, ...
OBJECTIVES: The impact of large-dose vitamin A supplementation given at intervals of 4 months on child mortality and morbidity was examined according to the time interval since dosing, number of...
Survival and the HL-A System in Acute Lymphoblastic Leukaemia
Lawler, Sylvia D., Klouda, P. T., Smith, P. G., Till, Morwenna M., Hardisty, R. M.
The relation between the HL-A antigens and survival has been studied in 58 patients with acute lymphoblastic leukaemia. Patients with the HL-A9 antigen had the best estimated median survival times,...
New variant Creutzfeldt-Jakob disease is more common in Britain than elsewhere
Ironside, J W, Knight, R S G, Will, R G, Smith, P G, Cousens, S N
Mortality of workers at the Sellafield plant of British Nuclear Fuels.
The mortality of all 14,327 people who were known to have been employed at the Sellafield plant of British Nuclear Fuels at any time between the opening of the site in 1947 and 31 December 1975 was...
Mortality among patients with ankylosing spondylitis after a single treatment course with x rays.
Mortality was studied in 14 111 patients with ankylosing spondylitis given a single course of x-ray treatment during 1935-54. Mortality from all causes combined was 66% greater than that of members...
Increasing prevalence of diabetes mellitus in children.
Patterson, C C, Thorogood, M, Mann, J I, Smith, P G, Heasman, M A, Clarke, J A
Association between Atherosclerotic Diseases and Carboxyhaemoglobin Levels in Tobacco Smokers
Wald, Nicholas, Howard, Susannah, Smith, P. G., Kjeldsen, Knud
In a cross-sectional study carboxyhaemoglobin (COHb) levels in tobacco smokers were found to provide a better indication of a person's risk of having developed certain atherosclerotic diseases,...
Between 1970 and 1975, 108 patients who presented with advanced or recurrent Hodgkin's disease and were free of disease after six courses of chemotherapy with mustine, vinblastine, procarbazine, and...
Johnston, P. G. B., Hardisty, R. M., Kay, H. E. M., Smith, P. G.
Analysis of the remission induction phase in three Medical Research Council trials of treatment of acute lymphoblastic leukaemia has provided evidence of the adverse effect of the combination of...
Toghill, P. J., Smith, P. G., Benton, Patricia, Brown, R. C., Matthews, H. L.
Twenty patients are described in whom liver damage appeared to be directly related to the administration of methyldopa. Sixteen had hepatitic syndromes from which they recovered on stopping...
Ross, D A, Kirkwood, B R, Binka, F N, Arthur, P, Dollimore, N, Morris, S S, ...
OBJECTIVES: The impact of large-dose vitamin A supplementation given at intervals of 4 months on child mortality and morbidity was examined according to the time interval since dosing, number of...
Survival and the HL-A System in Acute Lymphoblastic Leukaemia
Lawler, Sylvia D., Klouda, P. T., Smith, P. G., Till, Morwenna M., Hardisty, R. M.
The relation between the HL-A antigens and survival has been studied in 58 patients with acute lymphoblastic leukaemia. Patients with the HL-A9 antigen had the best estimated median survival times,...
Burkitt's Lymphoma: A Time-space Cluster of Cases in Bwanba County of Uganda
Morrow, R. H., Pike, M. C., Smith, P. G., Ziegler, J. L., Kisuule, A.
Seven cases of Burkitt's lymphoma have to date (March 1971) been diagnosed in the county of Bwamba in Uganda. All these patients had the clinical onset of their tumour in the 27 months from October...
Chronic iron overload in rats induces oval cells in the liver.
Liver damage induced by a variety of agents including hepatocarcinogens, alcohol, and virus induces proliferation of oval cells. In this study, iron overloading of the liver is used as a means of...
Carcinoid tumour of the common bile duct--a novel complication of von Hippel-Lindau syndrome.
Fellows, I W, Leach, I H, Smith, P G, Toghill, P J, Doran, J
A 30 year old man with von Hippel-Lindau syndrome presented with obstructive jaundice caused by a carcinoid tumour of the mid- and upper common bile duct. This association is probably causally...
Crohn's disease in Nottingham: a search for time-space clustering.
Miller, D S, Keighley, A, Smith, P G, Hughes, A O, Langman, M J
All cases of Crohn's disease in the Nottingham area were ascertained and the date and place of domicile and work at the time of onset of symptoms noted. Applying the Knox and Pike and Smith tests for...
Hepatocellular carcinoma in primary haemochromatosis in the absence of cirrhosis.
Fellows, I W, Stewart, M, Jeffcoate, W J, Smith, P G, Toghill, P J
Two patients with primary haemochromatosis are reported in whom hepatocellular carcinoma supervened despite removal of excess iron after venesection therapy. These are the first patients described in...
Dichotomy of protective cellular immune responses to human visceral leishmaniasis
Khalil, E A G, Ayed, N B, Musa, A M, Ibrahim, M E, Mukhtar, M M, Zijlstra, E E, ...
Healing/protective responses in human visceral leishmaniasis (VL) are associated with stimulation/production of Th1 cytokines, such as interferon IFN-γ, and conversion in the leishmanin skin test...
Parasympathetic excitation of sympathetic innervation after cholinesterase inhibition.
Beauregard, C. L., Smith, P. G.
1. Orbital parasympathetic innervation normally provides prejunctional muscarinic inhibition of sympathetic neurotransmission without activation of excitatory muscarinic receptors located on the...
Cousens, S. N., Zeidler, M., Esmonde, T. F., De Silva, R., Wilesmith, J. W., Smith, P. G., ...
OBJECTIVE: To identify changes in the occurrence of Creutzfeldt-Jakob disease that might be related to the epidemic of bovine spongiform encephalopathy. DESIGN: Epidemiological surveillance of the...
Wald, N, Howard, S, Smith, P G, Bailey, A
Carboxyhaemoglobin (COHb) levels in tobacco smokers vary throughout the day since they are affected by the pattern of tobacco consumption and the rate at which COHb is eliminated. A method is...
Cancer of the testis, socioeconomic status, and occupation.
Swerdlow, A J, Douglas, A J, Huttly, S R, Smith, P G
The risk of testicular cancer in relation to lifetime histories of socioeconomic status, occupation, and occupational exposures was examined in a case-control study in England. Interviews were...
Geographical distribution of cases of Creutzfeldt-Jakob disease in England and Wales 1970-84.
Cousens, S N, Harries-Jones, R, Knight, R, Will, R G, Smith, P G, Matthews, W B
Two hundred and sixty seven patients with a definite or probable diagnosis of Creutzfeldt-Jakob disease (CJD) were identified in an attempt to ascertain all cases of the disease in England and Wales...
A retrospective study of Creutzfeldt-Jakob disease in England and Wales 1970-1979. II: Epidemiology.
Will, R G, Matthews, W B, Smith, P G, Hudson, C
A comprehensive search yielded 121 confirmed cases of Creutzfeldt-Jakob disease who died in England and Wales in the decade 1970-1979, 31 probable cases and 10 possible cases. Descriptive...
Harries-Jones, R, Knight, R, Will, R G, Cousens, S, Smith, P G, Matthews, W B
An attempt was made to ascertain all cases of Creutzfeldt-Jakob disease occurring in England and Wales during the 5 year period 1980-1984. The mean annual mortality rate was 0.49/million; women were...
Mortality from injuries and other causes in a cohort of 21,800 Brazilian steel workers.
Barreto, S M, Swerdlow, A J, Smith, P G, Higgins, C D, Andrade, A
OBJECTIVES: Injury is the leading cause of death in the male working population of Brazil. An important fraction of these deaths are work related. Very few cohort studies of steel workers, and none...
A nested case-control study of fatal work related injuries among Brazilian steel workers.
Barreto, S M, Swerdlow, A J, Smith, P G, Higgins, C D
OBJECTIVES: To estimate the relative risk of death from work related injury in a steelworks, associated with exposure to various occupational hazards, sociodemographic factors, and medical history....
Maconochie, N., Doyle, P., Roman, E., Davies, G., Smith, P. G., Beral, V.
OBJECTION: To describe the methods used in the nuclear industry family study for which a comprehensive database has been assembled that links employment in the nuclear industry and dosimetry records...
Pike, M C, Casagrande, J, Smith, P G
It is now well established in case-control studies with individual matching that the statistical analysis must take the fact of individual matching into account. The problems of so doing have been...
A case-control study of the aetiology of cryptorchidism.
Swerdlow, A J, Wood, K H, Smith, P G
A study of cryptorchidism was undertaken based on patients identified through the Oxford Record Linkage Study. The cumulative lifetime incidence of archidopexy among males in the study area was...
Rodrigues, L C, Noel Gill, O, Smith, P G
STUDY OBJECTIVE--The aim was to assess the protection conferred by BCG given during the first year of life against tuberculosis among children of Asian ethnic origin born in England. DESIGN--This was...
Chronic liver disease associated with childhood ulcerative colitis
Toghill, P. J., Benton, K. P. E., Smith, P. G.
In a series of 301 patients with ulcerative colitis forty-eight developed the disease before the age of 20. In this group of forty-eight patients there were four cases of serious chronic liver...
Zicker, F., Smith, P. G., Luquetti, A. O., Oliveira, O. S.
Methods used to diagnose Trypanosoma cruzi infection differ in their ability to discriminate between sera from infected and uninfected individuals. We compared the results of an immunofluorescence...
Testicular cancer and antecedent diseases.
Swerdlow, A. J., Huttly, S. R., Smith, P. G.
A case-control study of the aetiology of testicular cancer was conducted using information obtained by interview and from case-notes of 259 cases with testicular cancer and two sets of control...
Hawkey, C. J., Holmes, C. H., Smith, P. G., Austin, E. B., Baldwin, R. W.
Reactivity of the monoclonal antibody 791T/36 with secondary malignant deposits has been investigated in frozen sections of 74 human liver biopsy specimens. There was no reactivity with hepatocytes...
Prenatal and familial associations of testicular cancer.
Swerdlow, A. J., Huttly, S. R., Smith, P. G.
In a case-control study of testis cancer 259 cases with testicular cancer, 238 controls treated at radiotherapy centres and 251 non-radiotherapy hospital in-patient controls were interviewed about...
Darby, S. C., Doll, R., Gill, S. K., Smith, P. G.
Mortality up to 1 January 1983 has been studied in 14,106 patients with ankylosing spondylitis given a single course of X-ray treatment during 1935-54. For neoplasms other than leukaemia or colon...
Kaposi's Sarcoma in Uganda: Geographic and Ethnic Distribution
Taylor, J. F., Smith, P. G., Bull, Diana, Pike, M. C.
Over the quinquennium 1964-68 the crude annual incidence of Kaposi's sarcoma in Uganda per million of the population was 7·9 overall, 14·6 for males and 1·1 for females. Statistical analysis...
Space-time clustering of Burkitt's lymphoma in the West Nile district of Uganda: 1961-1975.
Williams, E. H., Smith, P. G., Day, N. E., Geser, A., Ellice, J., Tukei, P.
Epidemiological data relating to all 202 patients diagnosed with Burkitt's Lymphoma (BL) in the West Nile District of Uganda in the period 1961 to 1975 have been reviewed and analysed. Statistically...
Dermatoglyphics in childhood leukaemia: a guide to prognosis and aetiology?
Till, M., Larrauri, S., Smith, P. G.
The results of analysis of the dermatoglyphics of 152 children with acute lymphoblastic leukaemia (ALL) (and the first-degree relatives of 54 of them) contrast with those of 31 children with acute...
Family studies in acute leukaemia in childhood: a possible association with autoimmune disease.
Till, M., Rapson, N., Smith, P. G.
Medical histories of themselves and their first-degree relatives were obtained from parents of 82 leukaemic children (54 acute lymphoblastic (ALL), 28 acute myeloblastic (AML)) and from control...
Mortality of wives of men dying with cancer of the penis.
Smith, P. G., Kinlen, L. J., White, G. C., Adelstein, A. M., Fox, A. J.
711 women were identified who in 1939 were married to men who died with cancer of the penis in England and Wales during the period 1964 to 1973. The records of women were traced through the National...
Characteristics of women with dysplasia or carcinoma in situ of the cervix uteri.
Harris, R. W., Brinton, L. A., Cowdell, R. H., Skegg, D. C., Smith, P. G., Vessey, M. P., ...
To identify risk factors for various cervical abnormalities, 237 women with abnoromal cervical smears and 422 control women were interviewed. Cervical biopsy specimens taken from the patients with...
Incidence of familial Hodgkin's disease.
Kerzin-Storrar, L., Faed, M. J., MacGillivray, J. B., Smith, P. G.
The family histories of 131 patients with histologically defined Hodgkin's disease (HD) were studied and 2,517 first and second degree relatives and spouses were identified and followed-up. The...
A proportionate study of cancer mortality among members of a vegetarian society.
Kinlen, L. J., Hermon, C., Smith, P. G.
A proportionate study was carried out of the causes of death of the 759 Vegetarian Society members whose deaths were recorded in Society records and whose death certificates could be traced. Compared...
Smith, P. G., Pike, M. C., Till, M. M., Hardisty, R. M.
Studies of space-time clustering of cases of childhood leukaemia have yielded equivocal results. This might be because the disease has a long and variable latent period, in which case the usual...
Peto, R., Pike, M. C., Armitage, P., Breslow, N. E., Cox, D. R., Howard, S. V., ...
The Medical Research Council has for some years encouraged collaborative clinical trials in leukaemia and other cancers, reporting the results in the medical literature. One unreported result which...
Peto, R., Pike, M. C., Armitage, P., Breslow, N. E., Cox, D. R., Howard, S. V., ...
Part I of this report appeared in the previous issue (Br. J. Cancer (1976) 34,585), and discussed the design of randomized clinical trials. Part II now describes efficient methods of analysis of...
Further studies of space-time clustering of Burkitt's lymphoma in Uganda.
Morrow, R. H., Pike, M. C., Smith, P. G.
All hospital-treated cases of Burkitt's lymphoma (BL), with onset of symptoms in the period 1963-68 and resident in the Lango and Acholi districts of Uganda, were identified. The average annual...
Cancer mortality and morbidity among workers at the Sellafield plant of British Nuclear Fuels.
Douglas, A. J., Omar, R. Z., Smith, P. G.
The mortality of all 14,282 workers employed at the Sellafield plant of British Nuclear Fuels between 1947 and 1975 was studied up to the end of 1988 and cancer incidence was examined from 1971 to...
Carpenter, L. M., Higgins, C. D., Douglas, A. J., Maconochie, N. E., Omar, R. Z., Fraser, P., ...
Cancer mortality in 40,761 employees of three UK nuclear industry facilities who had been monitored for external radiation exposure was examined according to whether they had also been monitored for...
Omar, R Z, Barber, J A, Smith, P G
The mortality of all 14 319 workers employed at the Sellafield plant of British Nuclear Fuels between 1947 and 1975 was studied up to the end of 1992, and cancer incidence was examined from 1971 to...
Smith, P G, Marshman, E, Newell, D R, Curtin, N J
The novel pyrrolopyrimidine-based antifolate LY231514 (MTA), inhibits multiple folate-requiring enzymes including thymidylate synthase, glycinamide ribonucleotide formyltransferase and dihydrofolate...