Heijckmann, A.C., Dumitrescu, B., Nieuwenhuijzen Kruseman, A.C., Geusens, P., Wolffenbuttel, B.H.R., Vries, J. De, ...
Vosse, D., Landewé, R., Garnero, P., Geusens, P.
Objective. There is a lack of knowledge on factors that reliably can predict radiological changes in patients with AS. We have investigated whether urinary C-terminal cross-linking telopeptide of...
Vosse, D., Heijckmann, C., Landewé, R., Geusens, P.
Objective. To compare the level of agreement of quantitative morphometry of the vertebrae on lateral views of the spine using conventional X-ray and using a dual X-ray absorptiometry device (DXA) in...
Van Staa, T.P., Geusens, P., Zhang, B., Leufkens, H.G.M., Boonen, A., Cooper, C.
OBJECTIVES: There are few data on the cost-effectiveness of bisphosphonates with oral glucocorticoids (GCs). An individual patient-based pharmaco-economic model was developed. METHODS: Data were...
Geusens, P, Malaise, M, De Clerck, L, Raeman, F, ...
OBJECTIVE: To compare the effects of continuous and intermittent celecoxib treatment in patients with knee or hip osteoarthritis in flare. METHODS: In this 24-week, prospective, randomised,...
Staa, T.P. Van, Geusens, P., Boonen, A., Leufkens, H.G.M., Cooper, C.
Objectives. There are few data on the cost-effectiveness of bisphosphonates with oral glucocorticoids (GCs). An individual patient-based pharmaco-economic model was developed. Methods. Data were...
Staa, T.P. Van, Geusens, P., Boonen, A., Leufkens, H.G.M., Cooper, C.
Objectives: Cost-effectiveness analyses are routinely based on data from group averages, restricting its generalizibility to those with below- or above-average risk. A pharmacoeconomic model that...
Van Staa, T. P., Geusens, P., Zhang, B., Leufkens, H. G. M., Boonen, A., Cooper, C.
Objectives. There are few data on the cost-effectiveness of bisphosphonates with oral glucocorticoids (GCs). An individual patient-based pharmaco-economic model was developed. Methods. Data were...
Staa, T.P. Van, Geusens, P., Kanis, J.A., Leufkens, H.G.M., Gehlbach, S., Cooper, C.
Background: Simple tools are needed to identify patients at high risk of fracture. Aim: To develop a simple clinical tool for assessing 5-year risk of fracture. Design: Cohort study. Methods: The...
Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. (2006)
Staa, T.P. Van, Geusens, P., Bijlsma, J.W.J., Leufkens, H.G.M., Cooper, C.
Objective. To determine whether patients with rheumatoid arthritis (RA) have an increased risk of fracture, and to estimate their long-term absolute fracture risk. Methods. We studied patients with...
Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis (2006)
Staa, T.P., Geusens, P., Bijlsma, J.W., Leufkens, H.G., Cooper, C.
OBJECTIVE: To determine whether patients with rheumatoid arthritis (RA) have an increased risk of fracture, and to estimate their long-term absolute fracture risk. METHODS: We studied patients with...
Van Staa, T.P., Geusens, P., Kanis, J.A., Leufkens, H.G., Gehlbach, S., Cooper, C.
BACKGROUND: Simple tools are needed to identify patients at high risk of fracture. AIM: To develop a simple clinical tool for assessing 5-year risk of fracture. DESIGN: Cohort study. METHODS: The...
Determinants of hyperkyphosis in patients with ankylosing spondylitis (2006)
VOSSE, D, LANDEWE, R, GEUSENS, P, Mielants, Herman, DOUGADOS, M, ...
Van Staa, T. P., Geusens, P., Zhang, B., Leufkens, H. G. M., Boonen, A., Cooper, C.
Objectives. There are few data on the cost-effectiveness of bisphosphonates with oral glucocorticoids (GCs). An individual patient-based pharmaco-economic model was developed. Methods. Data were...
Van Staa, T.P., Geusens, P., Kanis, J.A., Leufkens, H.G.M., Gehlbach, S., Cooper, C.
Background: Simple tools are needed to identify patients at high risk of fracture. Aim: To develop a simple clinical tool for assessing 5-year risk of fracture. Design: Cohort study. Methods: The...
Van Staa, T.P., Geusens, P., Kanis, J.A., Leufkens, H.G.M., Gehlbach, S., Cooper, C.
Background: Simple tools are needed to identify patients at high risk of fracture. Aim: To develop a simple clinical tool for assessing 5-year risk of fracture. Design: Cohort study. Methods: The...
Van Staa, T. P., Geusens, P., Zhang, B., Leufkens, H. G. M., Boonen, A., Cooper, C.
Objectives. There are few data on the cost-effectiveness of bisphosphonates with oral glucocorticoids (GCs). An individual patient-based pharmaco-economic model was developed. Methods. Data were...
Van Staa, T.P., Geusens, P., Kanis, J.A., Leufkens, H.G.M., Gehlbach, S., Cooper, C.
Background: Simple tools are needed to identify patients at high risk of fracture. Aim: To develop a simple clinical tool for assessing 5-year risk of fracture. Design: Cohort study. Methods: The...
Geusens, P, Haentjens, P, Mohan, S, ...
Characteristics and performance of an immunosorbent assay for human matrix Gla-protein (2005)
Schurgers, L.J., Teunissen, K.J., Knapen, M., Geusens, P., Heijde, D. Van Der, Kwaijtaal, M., ...
Van Staa, T.P., Geusens, P., Pols, H.A., De Laet, C., Leufkens, H.G., Cooper, C.
Background: Previous analyses of risk factors for glucocorticoid (GC)-induced osteoporosis have focused on the estimation of relative rather than absolute fracture probability. Aim: To estimate risk...
Newer drug treatments: Their effects on fracture prevention (2005)
Geusens, P, Reid, D, GEUSENS, Piet
Drug treatment of osteoporosis is based on the knowledge of mechanisms of bone turnover and the manipulation of the cellular components of bone turnover in terms of recruitment, activation and...
Cost-effectiveness analysis of Aclasta in Paget's disease of bone in Belgium (2005)
LECOMTE, P, DEVOGELAER, JP, Kaufman, Jean, GOEMAERE, S, GEUSENS, P, ENGBERSEN, A
Osteoporosis therapy: an example of putting evidence-based medicine into clinical practice (2005)
Hosking, D.J., Geusens, P., Rizzoli, R.
A major aim of evidence-based medicine is to assist clinical decision-making by providing the most current and reliable medical information. Systematic reviews and meta-analyses are important tools...
Osteoporosis therapy: an example of putting evidence-based medicine into clinical practice (2005)
Hosking, D.J., Geusens, P., Rizzoli, R.
A major aim of evidence-based medicine is to assist clinical decision-making by providing the most current and reliable medical information. Systematic reviews and meta-analyses are important tools...
Geusens, P., Pols, H.A.P., De Laet, C., Leufkens, H.G.M., Cooper, C.
Background: Previous analyses of risk factors for glucocorticoid (GC)-induced osteoporosis have focused on the estimation of relative rather than absolute fracture probability. Aim: To estimate risk...
The lunar achilles as a screening tool for osteoporosis: Comparison with spine DXA (2004)
PORIAU, S, GEUSENS, P, Van Den Bosch, Filip, De Keyser, Filip
De Keyser, F, Geusens, P, De Backer, Manu; U0039058, Malaise, M, Baeten, D, ...
Objective. To study T cell receptor (TCR) repertoire changes in synovial membrane over a 16 week period in patients with early rheumatoid arthritis (RA); and to study the influence of cyclosporin A...
Geusens, P, Vosse, D, Vanhoof, J, Van Tubergen, A, VAN DER HEIJDE, Desiree, ...
Objective. To study the prevalence of deformities of vertebrae and inter-vertebral discs in patients with ankylosing spondylitis (AS) in relation to fixed hyperkyphosis of the spine. Methods....
Geusens, P, Vosse, D, Vanhoof, J, Van Tubergen, A, VAN DER HEIJDE, Desiree, ...
Objective. To study the prevalence of deformities of vertebrae and inter-vertebral discs in patients with ankylosing spondylitis (AS) in relation to fixed hyperkyphosis of the spine. Methods....
Effect of risedronate on the risk of hip fracture in elderly women. (2001)
MCCLUNG, MR, GEUSENS, P, MILLER, PD, ZIPPEL, H, BENSEN, WG, ROUX, C, ...
Verhoeven, A. C., Boers, M., Te Koppele, J. M., Van Der Laan, W. H., Markusse, H. M., Geusens, P., ...
Objectives. Exploration of bone metabolism changes at different levels of disease activity, both with and without oral corticosteroid therapy, and prediction of changes in joint damage and bone...
VanderBorght, A., Geusens, P., Vandevyver, C., Raus, J., Stinissen, P.
Objective. Autoreactive T cells may contribute to the pathogenesis of rheumatoid arthritis (RA). We studied the T‐cell receptor (TCR) V‐gene repertoire in the...
Geusens, P, Vandevyver, C, Vanhoof, J, Stinissen, P, Declerck, K, Cassiman, Jean-Jacques; U0013884, ...
Cheng, X G, Geusens, P, ...
The problem of osteoporosis in men has recently been recognized as an important public health issue. To test the hypothesis that endocrine deficiency-mediated alterations in bone metabolism might...
Osteoporotic fractures, and especially hip fractures, are a leading cause of morbidity and mortality among elderly men. Among other factors, a decline in bone mass has been identified as the major...
Bone mineral density is already abnormally reduced at the moment of cardiac transplantation and bone loss occurs at an impressive rate in the first postoperative year. The aim of the study was to...
Koutri, R, Aerssens, J, Lowet, G, ...
The epidemiologic patterns of vertebral and femoral fractures are sufficiently different to suggest that they represent distinct disorders (type I versus type II osteoporosis) although osteopenia is...
Timing and quantification of bone loss in cardiac transplant recipients (1995)
To evaluate osteopenic bone disease in heart transplant patients, we prospectively measured bone mineral density (BMD) in 33 consecutive male recipients before hospital discharge and 1 year later,...
VANDEVYVER, C., GEUSENS, P., RAUS, J.
The association of rheumatoid arthritis (RA) with HLA-DRB1 allelcs indicates that at least one RA susceptibility gene is linked to the HLA class II region. Transporter associated with protein...
Total body mineral mass measured with dual photon absorptiometry in healthy children (1994)
Using dual photon absorptiometry, bone mineral content (BMC) and bone mineral density (BMD) of the total body and the lumbar spine were assessed in 97 healthy, Caucasian children aged 3-14 years....
Suiker, A M, Einhorn, T A, Geusens, P, Visser, W J, Van Herck, E, ...
Spontaneously diabetic BB rats were sham operated (SO) or ovariectomized (OVX) within days after onset and studied after 4, 8, and 12 weeks. Analyses included histomorphometry of proximal tibial...
Androgen resistance and deficiency have different effects on the growing skeleton of the rat (1994)
Van Herck, E, Geusens, P, Suiker, A, Visser, W, Chung, K, ...
Mature male, female, and androgen-resistant testicular feminized (Tfm) male rats of the same strain were sacrificed at the age of 120 days. Young male and Tfm rats were orchidectomized (orch) at 1...
Bassiouni, H, Koutri, R, Geusens, P
Thoracic kyphosis is clinically associated with osteoporosis as well as with osteoarthritis. Because misinterpretation of thoracic spine deformities on X-rays may lead to overdiagnosis of vertebral...
Vandeursen, H, Pittomvils, G, Boving, R, Geusens, P, ...
Thirty-six urinary stones were studied by computed tomography and bone densitometry in order to find a correlation between the chemical composition of the stones and the densitometric data. In vitro,...
Schot, P, Rush, E, Einhorn, T, Geusens, P, ...
Effects of androgen deficiency and androgen replacement on bone density, as measured with dual-energy X-ray absorptiometry (DXA) and single photon absorptiometry (SPA), cortical ratio (cortical...
The results of vibration analysis experiments and impact torsion tests performed on excised animal long bones were used to validate a simple beam model for the prediction of torsional stiffness from...
Application of microfocus x-ray radiography in materials and medical-research (1993)
Wevers, Martine; U0008503, Demeester, P, Lodewijckx, Marc; U0005411, Ni, Yicheng; U0014498, Marchal, Guy; U0008034, Jiang, Y, ...
The advantages of real-time microfocus radiography are evaluated for several applications. These advantages are mainly the small focal spot size (5 mum) leading to a very low geometrical unsharpness...
Geusens, P, Jiang, Y, Poppe, G, ...
Regional assessment of skeletal fluoride kinetics with 18f- - pet in bone disorders (1993)
Geusens, P, Vleugels, S, ...
Suiker, A M, Allewaert, K, Visser, W J, Geusens, P, ...
The effects of androgen and estrogen deficiency on skeletal homeostasis were studied in the guinea pig. Male and female adult (7 months old) guinea pigs were either sham operated (9 females and 7...
Changes in bone-mineral density after cardiac transplantation (1992)
Geusens, P, Nijs, Johan; U0014712, Borghs, H, Wouters, C, ...
Chloroquine levels in blood during chronic treatment of patients with rheumatoid arthritis (1992)
Blood levels of racemic chloroquine and its main metabolites desethylchloroquine and bisdesethylchloroquine were measured in 29 patients treated chronically for rheumatoid arthritis. In six patients,...
Aerssens, J, Vandeneynde, R, Peeters, J, Geusens, P, Devos, P, ...
The relation between bone mineralization and osteocalcin content was investigated in iliac crest cortical bone obtained at necropsy in young females and in two groups of elderly women with and...
Department of Nuclear Medicine, Katholieke Universteit Leuven, Belgium.
Seasonal variation in bone metabolism in young healthy subjects (1991)
Vanderschueren, Dirk; U0008390, Gevers, G, Dequeker, Jan; U0010267, Geusens, P, Nijs, Johan; U0014712, Devos, P, ...
Serum vitamin D metabolites and urinary calcium excretion; parameters of bone formation (serum alkaline phosphatase, serum osteocalcin); parameters of bone resorption (24 hour hydroxyprolinuria, 2...
Vanermen, H, Haghebaert, G, Geusens, P
The clinical, roentgenographic, and biochemical features of the dorsal and lumbar spine were reviewed in 72 postmenopausal women. Nineteen women had both osteoporosis (vertebral collapse) and...
This study was performed to assess whether the 1,25(OH)2 vitamin D3 stimulation test for osteoblastic function is influenced by a prostaglandin synthesis inhibitor (piroxicam). Thirty-four healthy...
Mineral metabolism and bone mass at peripheral and axial skeleton in diabetes mellitus (1988)
Bone mineral content (BMC), mineral homeostasis, and diabetes control were evaluated in 31 Caucasian insulin-dependent diabetic patients (disease duration 18.3 +/- 7.7 yr, mean +/- SD) with normal...
Mineral metabolism and bone mass at peripheral and axial skeleton in diabetes mellitus. (1988)
Auwerx, J, Dequeker, J, Bouillon, R, Geusens, P, Nijs, J
Bone mineral content (BMC), mineral homeostasis, and diabetes control were evaluated in 31 Caucasian insulin-dependent diabetic patients (disease duration 18.3 +/- 7.7 yr, mean +/- SD) with normal...
Genetic-determinants of bone-mineral content at the spine and radius - a twin study (1987)
Dequeker, Jan; U0010267, Nijs, Johan; U0014712, Verstraeten, A, Geusens, P, Gevers, G
Genetic-determinants of bone-mineral content at the spine and radius - a twin study (1986)
Dequeker, Jan; U0010267, Verstraeten, A, Geusens, P, Gevers, G, Nijs, Johan; U0014712
Intranasal calcitonin for the prevention of bone erosion and bone loss in rheumatoid arthritis.
Sileghem, A, Geusens, P, Dequeker, J
The effect of intranasal salmon calcitonin on pain, erosion progression, and bone loss in 40 women with rheumatoid arthritis was investigated. The study design was double blind, placebo controlled...
Vandevyver, C, Gu, X X, Geusens, P, Spaepen, M, Philippaerts, L, Cassiman, J J, ...
OBJECTIVES--To investigate whether T-cell receptor (TCR) beta chain germline alleles, either alone or in combination with a particular HLA-genotype, are associated with rheumatoid arthritis (RA)....
Vertebral fracture induced by chronic contained rupture of aortic aneurysm.
Boonen, A, Ghesquiere, B, Westhovens, R, Geusens, P, Dequeker, J, Boonen, S
Treatment with etidronate for men with idiopathic osteoporosis
GEUSENS, P., VANHOOF, J., RAUS, J., DEQUEKER, J., NIJS, J., JOLY, J.
Geusens, P., Dequeker, J., Vanhoof, J., Stalmans, R., Boonen, S., Joly, J., ...
OBJECTIVE—To study the effect of cyclic etidronate in secondary prevention of corticosteroid induced osteoporosis. METHODS—A double blind, randomised placebo controlled study comparing cyclic...
Prevalence of rheumatic diseases in a rheumatological outpatient practice
Vanhoof, J, Declerck, K, Geusens, P
Methods: Rheumatological diagnoses of 3751 consecutive new and returning patients were recorded using a standard diagnosis form.
Geusens, P, Lems, W, Laan, R, Struijs, A, Van Staa, T P, ...
Heijckmann, A. C., Drent, M., Dumitrescu, B., De Vries, J., Nieuwenhuijzen Kruseman, A. C., Wolffenbuttel, B. H.R., ...