Weiss, W. J., Jacobus, N. V., Petersen, P. J., Testa, Raymond T.
The in-vitro activities of two glycylcyclines, DMG-MINO and DMG-DMDOT, and several comparative agents were determined against 263 enterococci, 102 methicillin-resistant Staphylococcus aureus and 55...
Petersen, P. J., Jacobus, N. V., Weiss, W. J., Sum, P. E., Testa, R. T.
The 9-t-butylglycylamido derivative of minocycline (TBG-MINO) is a recently synthesized member of a novel group of antibiotics, the glycylcyclines. This new derivative, like the first glycylcyclines,...
Alksne, L. E., Burgio, P., Hu, W., Feld, B., Singh, M. P., Tuckman, M., ...
Protein secretion is an essential process for bacterial growth, yet there are few if any antimicrobial agents which inhibit secretion. An in vivo, high-throughput screen to detect secretion...
Singh, M. P., Petersen, P. J., Weiss, W. J., Kong, F., Greenstein, M.
Saccharomicins A and B, two new heptadecaglycoside antibiotics, were isolated from the fermentation broth of the rare actinomycete Saccharothrix espanaensis. They represent a novel class of...
Singh, M. P., Petersen, P. J., Weiss, W. J., Janso, J. E., Luckman, S. W., Lenoy, E. B., ...
Mannopeptimycins α, β, γ, δ, and ɛ are new cyclic glycopeptide antibiotics produced by Streptomyces hygroscopicus LL-AC98. Mannopeptimycins γ, δ, and ɛ, which have an isovaleryl substitution...
Kuck, N A, Jacobus, N V, Petersen, P J, Weiss, W J, Testa, R T
Tazobactam (YTR-830H), a novel beta-lactamase inhibitor, was compared with clavulanic acid and sulbactam for enhancement of the activity of piperacillin against beta-lactamase-producing,...
Testa, R T, Petersen, P J, Jacobus, N V, Sum, P E, Lee, V J, Tally, F P
N,N-Dimethylglycylamido (DMG) derivatives of minocycline and 6-demethyl-6-deoxytetracycline are new semisynthetic tetracyclines referred to as the glycylcyclines. The in vitro activities of the...
In vitro and in vivo activities of LJC10,627, a new carbapenem with stability to dehydropeptidase I.
Petersen, P J, Jacobus, N V, Weiss, W J, Testa, R T
The activity of LJC10,627 was compared with the activities of imipenem and other antibiotics. LJC10,627 was more active against most members of the family Enterobacteriaceae, Pseudomonas spp., and...
Singh, M P, Petersen, P J, Jacobus, N V, Maiese, W M, Greenstein, M, Steinberg, D A
The bioxalomycins, a novel complex of broad-spectrum antibiotics, were isolated from fermentations of Streptomyces viridodiastaticus subsp. "litoralis" LL-31F508. Bioxalomycin alpha 2, the major...
Uses of Staphylococcus aureus GeneChips in Genotyping and Genetic Composition Analysis
Dunman, P. M., Mounts, W., McAleese, F., Immermann, F., Macapagal, D., Marsilio, E., ...
Understanding the relatedness of strains within a bacterial species is essential for monitoring reservoirs of antimicrobial resistance and for epidemiological studies. Pulsed-field gel...
Petersen, P. J., Jacobus, N. V., Weiss, W. J., Sum, P. E., Testa, R. T.
The 9-t-butylglycylamido derivative of minocycline (TBG-MINO) is a recently synthesized member of a novel group of antibiotics, the glycylcyclines. This new derivative, like the first glycylcyclines,...
Alksne, L. E., Burgio, P., Hu, W., Feld, B., Singh, M. P., Tuckman, M., ...
Protein secretion is an essential process for bacterial growth, yet there are few if any antimicrobial agents which inhibit secretion. An in vivo, high-throughput screen to detect secretion...
Singh, M. P., Petersen, P. J., Weiss, W. J., Kong, F., Greenstein, M.
Saccharomicins A and B, two new heptadecaglycoside antibiotics, were isolated from the fermentation broth of the rare actinomycete Saccharothrix espanaensis. They represent a novel class of...
Singh, M. P., Petersen, P. J., Weiss, W. J., Janso, J. E., Luckman, S. W., Lenoy, E. B., ...
Mannopeptimycins α, β, γ, δ, and ɛ are new cyclic glycopeptide antibiotics produced by Streptomyces hygroscopicus LL-AC98. Mannopeptimycins γ, δ, and ɛ, which have an isovaleryl substitution...
Kuck, N A, Jacobus, N V, Petersen, P J, Weiss, W J, Testa, R T
Tazobactam (YTR-830H), a novel beta-lactamase inhibitor, was compared with clavulanic acid and sulbactam for enhancement of the activity of piperacillin against beta-lactamase-producing,...
Testa, R T, Petersen, P J, Jacobus, N V, Sum, P E, Lee, V J, Tally, F P
N,N-Dimethylglycylamido (DMG) derivatives of minocycline and 6-demethyl-6-deoxytetracycline are new semisynthetic tetracyclines referred to as the glycylcyclines. The in vitro activities of the...
In vitro and in vivo activities of LJC10,627, a new carbapenem with stability to dehydropeptidase I.
Petersen, P J, Jacobus, N V, Weiss, W J, Testa, R T
The activity of LJC10,627 was compared with the activities of imipenem and other antibiotics. LJC10,627 was more active against most members of the family Enterobacteriaceae, Pseudomonas spp., and...
Singh, M P, Petersen, P J, Jacobus, N V, Maiese, W M, Greenstein, M, Steinberg, D A
The bioxalomycins, a novel complex of broad-spectrum antibiotics, were isolated from fermentations of Streptomyces viridodiastaticus subsp. "litoralis" LL-31F508. Bioxalomycin alpha 2, the major...
Uses of Staphylococcus aureus GeneChips in Genotyping and Genetic Composition Analysis
Dunman, P. M., Mounts, W., McAleese, F., Immermann, F., Macapagal, D., Marsilio, E., ...
Understanding the relatedness of strains within a bacterial species is essential for monitoring reservoirs of antimicrobial resistance and for epidemiological studies. Pulsed-field gel...