Kotsonis, P, Frey, A, Fröhlich, L G, Hofmann, H, Reif, A, Wink, D A, ...
Nitric oxide (NO) synthases (NOSs), which catalyse the oxidation of L-arginine to L-citrulline and an oxide of nitrogen, possibly NO or nitroxyl (NO-), are subject to autoinhibition by a mechanism...
Kotsonis, P, Fröhlich, L G, Shutenko, Z V, Horejsi, R, Pfleiderer, W, Schmidt, H H
The underlying mechanisms regulating the activity of the family of homodimeric nitric oxide synthases (NOSs) and, in particular, the requirement for (6R)-5,6,7,8-tetrahydro-L-biopterin (H(4)Bip) are...
Kotsonis, P, Frey, A, Fröhlich, L G, Hofmann, H, Reif, A, Wink, D A, ...
Nitric oxide (NO) synthases (NOSs), which catalyse the oxidation of L-arginine to L-citrulline and an oxide of nitrogen, possibly NO or nitroxyl (NO-), are subject to autoinhibition by a mechanism...
Kotsonis, P, Fröhlich, L G, Shutenko, Z V, Horejsi, R, Pfleiderer, W, Schmidt, H H
The underlying mechanisms regulating the activity of the family of homodimeric nitric oxide synthases (NOSs) and, in particular, the requirement for (6R)-5,6,7,8-tetrahydro-L-biopterin (H(4)Bip) are...
1. The effects of the beta 2-adrenoceptor agonist, procaterol, on sympathetic neuroeffector transmission were studied in the pithed adrenal demedullated rat to determine if generation of angiotensin...
Majewski, H, Kotsonis, P, Murphy, T V, Barrington, M
It has been proposed that protein kinase C (PKC) in sympathetic nerves is activated during action-potential evoked release of noradrenaline and helps maintain transmitter output. We studied this...
Iannazzo, L, Kotsonis, P, Majewski, H
The effects of various phorbol-based protein kinase C (PKC) activators on the electrical stimulation-induced (S-I) release of serotonin and acetylcholine was studied in rat brain cortical slices...
Kotsonis, P, Funk, L, Prountzos, C, Iannazzo, L, Majewski, H
The ability of several phorbol ester protein kinase C (PKC) activators (phorbol 12, 13-dibutyrate, PDB; phorbol 12, 13-diacetate, PDA; and 12-deoxyphorbol 13-acetate, dPA) to down-regulate PKC was...
Schroeder, G. E., Kotsonis, P., Musgrave, I. F., Majewski, H.
1. The role of protein kinase C in the modulation of noradrenaline release was investigated in mouse cortical slices which were pre-incubated with [3H]-noradrenaline. The aim was to investigate the...
1. The effects of various protein kinase C (PKC) activators on the stimulation-induced (S-I) release of noradrenaline and dopamine was studied in rat cortical slices pre-incubated with...
Kotsonis, P., Binko, J., Majewski, H.
1. The biosynthesis of noradrenaline following sympathetic nerve activation was investigated in rat atria. In particular the time course of noradrenaline synthesis changes, the relationship of...