P. M.

Perceiving identical sounds as speech or non-speech modulates activity in the left posterior superior temporal sulcus (2006)

  • Möttönen,
  • R.,
  • Calvert,
  • G.A.,
  • Jääskeläinen,
  • I.P.,
  • ...

The left superior temporal cortex shows greater responsiveness to speech than to non-speech sounds according to previous neuroimaging studies, suggesting that this brain region has a special role in...

The ontogeny of neuropathic pain: postnatal onset of mechanical allodynia in rat spared nerve injury (SNI) and chronic constriction injury (CCI) models (2005)

Neuropathic pain is known to occur in children but remains poorly understood and treated. The aim here was to establish a model of neuropathic pain in neonatal and young rodents. In the adult the...

Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy (2005)

  • Tschernutter,
  • M.,
  • Schlichtenbrede,
  • F.C.,
  • Howe,
  • S.,
  • ...

The Royal College of Surgeons (RCS) rat is a well-characterized model of autosomal recessive retinitis pigmentosa (RP) due to a defect in the retinal pigment epithelium (RPE). It is homozygous for a...

Mutations within the transcription factor PROP1 are rare in a cohort of patients with sporadic combined pituitary hormone deficiency (CPHD) (2005)

  • Turton,
  • J.P.,
  • Mehta,
  • A.,
  • Raza,
  • J.,
  • ...

Objective Mutations within the pituitary-specific paired-like homeobox gene PROP1 have been described in 50-100% of patients with familial combined pituitary hormone deficiency (CPHD). We screened a...

Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy (2005)

  • Taylor,
  • P.D.,
  • McConnell,
  • J.,
  • Khan,
  • I.Y.,
  • ...

We previously reported that prenatal and suckling exposure to a maternal diet rich in animal fat leads to cardiovascular dysfunction in young adult rat offspring with subsequent development of...

Assessing the acceptability and feasibility of the MEND Programme in a small group of obese 7-11-year-old children (2005)

  • Sacher,
  • P.M.,
  • Chadwick,
  • P.,
  • Wells,
  • J.C.,
  • ...

BACKGROUND AND AIMS: An uncontrolled, pilot study to evaluate feasibility and acceptability of a new community based childhood obesity treatment programme. METHODS: The mind, exercise, nutrition and...

Bladder extrophy (2005)

  • Sellaturay,
  • S.,
  • Arya,
  • M.,
  • Johal,
  • N.,
  • ...

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates (2005)

  • Ross,
  • A.J.,
  • May-Simera,
  • H.,
  • Eichers,
  • E.R.,
  • ...

The evolutionarily conserved planar cell polarity (PCP) pathway (or noncanonical Wnt pathway) drives several important cellular processes, including epithelial cell polarization, cell migration and...

RP405 (2005)

  • Sellaturay,
  • S.,
  • Arya,
  • M.,
  • Johal,
  • N.,
  • ...

Designing clinical interventions for children with specific memory disorders (2005)

  • Rankin,
  • P.M.,
  • Hood,
  • J.

Despite increasing research into the severe effects of childhood memory disorders, there is currently a paucity of evidence available to inform the design of appropriate rehabilitation strategies....

Contractile properties of the developing fetal sheep bladder (2005)

  • Nyirady,
  • P.,
  • Thiruchelvam,
  • N.,
  • Godley,
  • M.L.,
  • ...

Aim: To characterise the developmental changes to the normal bladder by examining the in vitro contractile properties of the fetal sheep detrusor smooth muscle bladder at different gestational ages....

New Alstrom syndrome phenotypes based on the evaluation of 182 cases (2005)

BACKGROUND: Alstrom syndrome is a recessively inherited genetic disorder characterized by congenital retinal dystrophy that leads to blindness, hearing impairment, childhood obesity, insulin...

Quantitative assessments of the effects of a single exercise session on muscles in juvenile dermatomyositis (2005)

  • Maillard,
  • S.M.,
  • Jones,
  • R.,
  • Owens,
  • C.M.,
  • ...

Objective. To investigate the short-term effects of exercise on muscle inflammation in children with juvenile dermatomyositis (juvenile DM). Magnetic resonance imaging (MRI), muscle strength, and...

Soluble adhesion molecules in acute disseminated encephalomyelitis (2005)

  • Martino,
  • D.,
  • Branson,
  • J.A.,
  • Church,
  • A.J.,
  • ...

Soluble adhesion molecules are overexpressed in neuroinflammatory disorders. Their synthesis parallels that of their membrane-bound counterparts, which modulate lymphocyte transmigration through the...

Trends in waist circumferences in young British children: a comparative study (2005)

OBJECTIVE: To compare waist circumference (a measure of central fatness) and body mass index (BMI, a measure of general fatness) between a contemporary cohort and similar aged British children...

Challenges in the provision of ICU services to HIV infected children in resource poor settings: a South African case study (2005)

  • Jeena,
  • P.M.,
  • McNally,
  • L.M.,
  • Stobie,
  • M.,
  • ...

The HIV/AIDS epidemic has placed increasing demands on limited paediatric intensive care services in developing countries. The decision to admit HIV infected children with Pneumocystis carinii...

The role of unilateral nephrectomy in the treatment of nephrogenic hypertension in children (2005)

  • Johal,
  • N.S.,
  • Kraklau,
  • D.,
  • Cuckow,
  • P.M.

OBJECTIVES To define the efficacy of unilateral nephrectomy in a large series of patients presenting with renal disease and hypertension, as the latter may be a prominent finding in children with...

Health care providers' orientations towards common low back pain predict perceived harmfulness of physical activities and recommendations regarding return to normal activity (2005)

The Pain Attitudes and Beliefs Scale for Physiotherapists (PABS-PT) differentiates between a biomedical versus a biopsychosocial treatment orientation with regard to common low back pain. This study...

Homozygous disruption of P450 side-chain cleavage (CYP11A1) is associated with prematurity, complete 46,XY sex reversal, and severe adrenal failure (2005)

  • Hiort,
  • O.,
  • Holterhus,
  • P.M.,
  • Werner,
  • R.,
  • ...

Disruption of the P450 side-chain cleavage cytochrome (P450scc) enzyme due to deleterious mutations of the CYP11A1 gene is thought to be incompatible with fetal survival because of impaired...

How do specific memory disorders present in the school classroom? (2005)

  • Hood,
  • J.,
  • Rankin,
  • P.M.

Childhood memory disorders have received increasing empirical investigation over recent years and reviews of the dissociations within the developmental memory system are now available. However, there...

Immediate effects of methylphenidate on cognitive attention skills of children with attention-deficit-hyperactivity disorder (2005)

  • Hood,
  • J.,
  • Baird,
  • G.,
  • Rankin,
  • P.M.,
  • ...

This study investigated the immediate effects of stimulant medication (methylphenidate) on cognitive attention processes in children with attention-deficit-hyperactivity disorder (ADHD). Thirteen...

Renal outcome following heminephrectomy for duplex kidney (2005)

Purpose: We evaluated functional outcome following heminephrectomy in duplex kidneys. Materials and Methods: A total of 10 1 patients were identified who underwent upper or lower pole heminephrectomy...

Lack of serum oligoclonal antibody responses to Chlamydophila pneumoniae in multiple sclerosis (2005)

Chlamydophila pneumoniae has been proposed as an aetiological agent in MS via a mechanism involving molecular mimicry. We undertook to investigate whether the presence of CSF oligoclonal IgG OCB or...

An in-silico model of epithelial cell interactions (2005)

  • Maheswaran,
  • S.,
  • Hammond,
  • P.,
  • Speight,
  • P.M.

0073

Letter to the editor (2005)

Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy (2005)

  • Tschernutter,
  • M.,
  • Schlichtenbrede,
  • F.C.,
  • Howe,
  • S.,
  • ...

The Royal College of Surgeons (RCS) rat is a well-characterized model of autosomal recessive retinitis pigmentosa (RP) due to a defect in the retinal pigment epithelium (RPE). It is homozygous for a...

Predominant rod photoreceptor degeneration in Leber congenital amaurosis (2005)

PURPOSE: An unusual retinal vascular morphology in an enucleated eye from a patient with Leber congenital amaurosis (LCA) has been associated with a mutation in AIPL1. The AIPL1 protein is expressed...

Visual functioning and quality of life in the SubFoveal Radiotherapy Study (SFRADS): SFRADS report 2 (2005)

  • Stevenson,
  • M.R.,
  • Hart,
  • P.M.,
  • Chakravarthy,
  • U.,
  • ...

AIMS: To determine whether or not self reported visual functioning and quality of life in patients with choroidal neovascularisation caused by age related macular degeneration (AMD) is better in...

Roughness response genes in osteoblasts (2004)

  • Brett,
  • P.M.,
  • Harle,
  • J.,
  • Salih,
  • V.,
  • ...

Urinary outflow obstruction increases apoptosis and deregulates Bcl-2 and Bax expression in the fetal ovine bladder (2003)

  • Thiruchelvam,
  • N.,
  • Nyirady,
  • P.,
  • Peebles,
  • D.M.,
  • ...

During organogenesis, net growth of tissues is determined by a balance between proliferation, hypertrophy, and apoptotic death. Human fetal bladder outflow obstruction is a major cause of end-stage...

Neurotransmission and viscoelasticity in the ovine fetal bladder after in utero bladder outflow obstruction (2003)

  • Thiruchelvam,
  • N.,
  • Wu,
  • C.,
  • David,
  • A.,
  • ...

Fetal bladder outflow obstruction, predominantly caused by posterior urethral valves, results in significant urinary tract pathology; these lesions are the commonest cause of end-stage renal failure...

Chicken DT40 cells stably transfected with the rat P2X7 receptor ion channel: a system suitable for the study of purine receptor-mediated cell death (2003)

  • Hillman,
  • K.A.,
  • Harada,
  • H.,
  • Chan,
  • C.M.,
  • ...

We have generated and characterised a clone of chicken DT40 lymphocytes stably transfected with the rat P2X(7) receptor (rP2X(7)). Successful transfection was confirmed by Western blotting. Under...

Differential genotyping in periodontitis (2003)

  • Brett,
  • P.M.,
  • Zygogianni,
  • P.,
  • Griffiths,
  • G.S.,
  • ...

38

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. (2003)

  • Segurado,
  • R.,
  • Detera-Wadleigh,
  • S.D.,
  • Levinson,
  • D.F.,
  • ...

Genome scans of bipolar disorder (BPD) have not produced consistent evidence for linkage. The rank-based genome scan meta-analysis (GSMA) method was applied to 18 BPD genome scan data sets in an...

Spontaneous intestinal perforation and Candida peritonitis presenting as extensive necrotizing enterocolitis (2003)

  • Robertson,
  • N.J.,
  • Kuna,
  • J.,
  • Cox,
  • P.M.,
  • ...

Spontaneous intestinal perforation (SIP) has been increasingly reported in very-low-birthweight (VLBW) infants, although it is still less common than necrotizing enterocolitis (NEC). In around...

Spontaneous intestinal perforation and Candida peritonitis presenting as extensive necrotizing enterocolitis (2003)

  • Robertson,
  • N.J.,
  • Kuna,
  • J.,
  • Cox,
  • P.M.,
  • ...

Spontaneous intestinal perforation (SIP) has been increasingly reported in very-low-birthweight (VLBW) infants, although it is still less common than necrotizing enterocolitis (NEC). In around...

The jugular foramen in complex and syndromic craniosynostosis and its relationship to raised intracranial pressure (2003)

BACKGROUND AND PURPOSE: Complex and syndromic craniosynostosis can be complicated by raised intracranial pressure (ICP), which in the absence of other identifiable origins, is probably caused by...

An unusual steroid-producing ovarian tumour: case report (2002)

  • Stephens,
  • J.W.,
  • Katz,
  • J.R.,
  • McDermott,
  • N.,
  • ...

The rapid onset of virilization in a post-menopausal woman is usually the result of androgen secretion from a tumour of adrenal or ovarian origin. Androgen secreting neoplasms of the ovary are rare...

Effects of in utero bladder outflow obstruction on fetal sheep detrusor contractility, compliance and innervation (2002)

  • Nyirady,
  • P.,
  • Thiruchelvam,
  • N.,
  • Fry,
  • C.H.,
  • ...

PURPOSE: Congenital bladder outflow obstruction caused by posterior urethral valves is a common cause of end stage renal failure in boys. We hypothesized that fetal bladder outflow obstruction...

HPV types in HIV-related dysplastic warts (2002)

  • Sancheng,
  • M.,
  • Liu,
  • H.,
  • Du,
  • M.,
  • ...

0896

Characterization of CD3+ CD4- CD8 - (double negative) T cells in patients with Systemic Lupus Erythematosus: production of IL-4 (2002)

  • Dean,
  • G.S.,
  • Anand,
  • A.,
  • Blofeld,
  • A.,
  • ...

Systemic lupus erythematosus (SLE) is a chronic autoimmune rheumatic disease that may affect every organ or system in the body. We have shown previously that the TCR alphabeta+ subpopulation of CD3+...

Transmural repolarisation in the left ventricle in humans during normoxia and ischaemia (2001)

  • Taggart,
  • P.,
  • Sutton,
  • P.M.,
  • Opthof,
  • T.,
  • ...

BACKGROUND: Studies in isolated tissues and myocytes show different repolarisation properties in subepicardium, midmyocardium and subendocardium. Whether these differences are present in vivo and are...

Refocusing of B-cell responses following a single amino acid substitution in an antigen (2001)

Intranasal immunization of BALB/c strain mice was carried out using baculovirus-derived human chorionic gonadotrophin (hCG) ?-chain, together with Escherichia coli heat-labile enterotoxin....

3D GIS - 3D London - Virtual London (2000)

  • Batty,
  • M.,
  • Chapman,
  • D.,
  • Evans,
  • S.,
  • ...

28 September

Bone mineral content and bone mineral metabolism: changes after growth hormone treatment in juvenile chronic arthritis (2000)

  • Rooney,
  • M.,
  • Davies,
  • U.M.,
  • Reeve,
  • J.,
  • ...

OBJECTIVE: To determine whether growth hormone (rhGH) affects bone mineral metabolism and bone mineral content (BMC, g/cm) in a therapeutic trial of recombinant growth hormone in growth retarded...

Data Communications (2000)

Editorial (2000)

  • Bouloux,
  • P.M.,
  • Harris,
  • P.

Editorial (2000)

  • Bouloux,
  • P.M.,
  • Harris,
  • P.

Photodynamic therapy for palliation of unresectable pancreatic cancer (1999)

Meeting: Digestive Diseases Week, May 1999, Orlando

Prognostic factors in patients progressing after cisplatin based chemotherapy for malignant non-seminomatous germ cell tumours (1999)

  • Fossa,
  • S.D.,
  • Stenning,
  • S.P.,
  • Gerl,
  • A.,
  • ...

The aim of this study was to define prognostic parameters for survival in patients with malignant germ cell tumours progressing after platinum-based induction chemotherapy with or without surgery. A...

Link Calibration Technique (1998)

  • Creaney,
  • S.,
  • Crummey,
  • T.,
  • Fergusson,
  • R.J.,
  • ...

The effect of photodynamic therapy on rat buccal mucosa (1998)

  • Komerik,
  • N.,
  • Speight,
  • P.M.,
  • Curnow,
  • A.,
  • ...

978

The pathology of oral cancer and precancer (1996)

  • Speight,
  • P.M.,
  • Farthing,
  • P.,
  • Bouquot,
  • J.

The epidemiology of oral cancer (1996)

  • Hindle,
  • I.,
  • Downer,
  • M.C.,
  • Speight,
  • P.M.

Oral health week (1996)

  • Desmond,
  • J.,
  • Downer,
  • M.C.,
  • Moles,
  • D.R.,
  • ...
 
Additional Information

Publishing period:

1966 - 2006 (260)

Co-authors: