P. Mahavadi

Alveolar oxidative stress is associated with elevated levels of nonenzymatic low-molecular-weight antioxidants in patients with different forms of chronic fibrosing interstitial lung diseases (2009)

Markart, P., Luboeinski, T., Korfei, M., Schmidt, R., Wygrecka, M., Mahavadi, P., ...

Increasing evidence indicates that disequilibrium of the alveolar oxidant-antioxidant balance may play a role in the pathogenesis of chronic fibrosing lung diseases. Excessive production of oxidants...

Recombinant production of a hybrid plasminogen activator composed of surfactant protein B and low-molecular-weight urokinase (2008)

Ruppert, C., Mahavadi, P., Wygrecka, M., Weaver, T.E., Magdolen, V., Idell, S., ...

Intraalveolar fibrin deposition is commonly observed during acute inflammatory and chronic interstitial lung diseases and may contribute to impairment of surfactant function and gas exchange. We...

Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis (2008)

Korfei, M., Ruppert, C., Mahavadi, P., Henneke, I., Markart, P., Koch, M., ...

RATIONALE: The molecular pathomechanisms underlying idiopathic pulmonary fibrosis (IPF) are elusive, but chronic epithelial injury has recently been suggested as key event. OBJECTIVES: We...