Sullivan, P.F., De Geus, E.J., Willemsen, G., James, M.R., Smit, J.H., Zandbelt, T., ...
Major depressive disorder (MDD) is a common complex trait with enormous public health significance. As part of the Genetic Association Information Network initiative of the US Foundation for the...
Chen, W., Zhou, K., Sham, P., Franke, B., Kuntsi, J., Campbell, D., ...
Attention deficit hyperactivity disorder (ADHD) is a discrete clinical syndrome characterized by the triad of inattention, hyperactivity, and impulsivity in the context of marked impairments....
Brookes, K, Xu, X, Chen, W, Zhou, K, Neale, B, Lowe, N, ...
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, starting in early childhood and persisting into adulthood in the majority of cases. Family and twin studies...
Brookes, K., Xu, X., Chen, W., Zhou, K., Neale, B., Lowe, N., ...
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, starting in early childhood and persisting into adulthood in the majority of cases. Family and twin studies...
The diagnostic interview for psychoses (DIP): development, reliability and applications (2006)
Castle, D. J., Jablensky, A., McGrath, J. J., Carr, V., Morgan, V., Waterreus, A., ...
Background: We describe the development, reliability and applications of the Diagnostic Interview for Psychoses (DIP), a comprehensive interview schedule for psychotic disorders. Method: The DIP is...
The diagnostic interview for psychoses (DIP): development, reliability and applications (2006)
Castle, D. J., Jablensky, A., McGrath, J. J., Carr, V., Morgan, V., Waterreus, A., ...
Background. We describe the development, reliability and applications of the Diagnostic Interview for Psychoses (DIP), a comprehensive interview schedule for psychotic disorders. Method. The DIP is...
The diagnostic interview for psychoses (DIP): development, reliability and applications (2006)
Castle, D. J., Jablensky, A., McGrath, J. J., Carr, V., Morgan, V., Waterreus, A., ...
Background. We describe the development, reliability and applications of the Diagnostic Interview for Psychoses (DIP), a comprehensive interview schedule for psychotic disorders. Method. The DIP is...
The diagnostic interview for psychoses (DIP): development, reliability and applications (2006)
Castle, D. J., Jablensky, A., McGrath, J. J., Carr, V., Morgan, V., Waterreus, A., ...
Background: We describe the development, reliability and applications of the Diagnostic Interview for Psychoses (DIP), a comprehensive interview schedule for psychotic disorders. Method: The DIP is...
Conduct problems in children and adolescents: a twin study (2004)
Van Den Bree, Marianne Bernadette, Scourfield, J., Martin, N., McGuffin, P.
Conduct problems in children and adolescents: a twin study (2004)
Van Den Bree, Marianne Bernadette, Scourfield, J., Martin, N., McGuffin, P.
A mitochondrial DNA sequence variant associated with schizophrenia and oxidative stress (2003)
Marchbanks, R.M., Ryan, Margaret, Day, I.N.M., Owen, M., McGuffin, P., Whatley, S.A.
We have previously reported a changed mitochondrial (mt) gene expression in brain from patients with schizophrenia [Schizophr. Res. 14 (1995) 203]; now, we describe the distribution in the mtDNA from...
RAT LIVER TRYPTOPHAN PYRROLASE ACTIVITY AND GENE EXPRESSION DURING ALCOHOL WITHDRAWAL (2000)
Oretti, R. G., Bano, S., Azani, M. O., Badawy, A. A.-B., Morgan, C. J., McGUFFIN, P., ...
Rat liver tryptophan (Trp) pyrrolase activity and gene expression were studied in relation to the alcohol-withdrawal syndrome (AWS). Both activity and gene expression were enhanced after withdrawal...
A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs (1999)
Williams, N. M., Rees, M. I., Holmans, P., Norton, N., Cardno, A. G., Jones, L. A., ...
We undertook a systematic search for linkage in 196 affected sibling pairs (ASPs) with DSMIV schizophrenia. In stage 1 we typed 97 ASPs with 229 microsatellite markers at an average inter-marker...
DNA pooling identifies QTLs on chromosome 4 for general cognitive ability in children (1999)
Fisher, PJ, Turic, D, Williams, NM, McGuffin, P, Asherson, P, Ball, D, ...
The gene for Darier's desease maps to chromosome 12q23-q24.1 (1993)
Craddock, N., Dawson, E., Burge, S., Parfitt, L., Mant, R., Roberts, Q., ...
The publishers wish to apologise for mistakenly publishing the above paper in the Short Communications section of the November issue of Human Molecular Genetics. The paper should have appeared as the...
Simultaneous quantification of several mRNA species by solution hybridisation with oligonucleotides.
Daniels, J, Holmans, P, Williams, N, Turic, D, McGuffin, P, Plomin, R, ...
Allelic association studies provide the most powerful method for locating genes of small effect contributing to complex diseases and traits. However, in outbred populations, allelic association is...
Simulation of Mendelism revisited: the recessive gene for attending medical school.
Much of the recent confusion concerning studies of complex phenotypes such as neuropsychiatric disorders may derive from the inappropriate assumption of simple Mendelian transmission. This has...
McGuffin, P, Sargeant, M, Hetti, G, Tidmarsh, S, Whatley, S, Marchbanks, R M
The report of a putative schizophrenia susceptibility gene linked to markers in the chromosome 5q11-q13 region and subsequent failures of replication have provoked considerable controversy. We here...
Platelet monoamine oxidase (MAO) activity: evidence for a single major locus.
Rice, J, McGuffin, P, Goldin, L R, Shaskan, E G, Gershon, E S
Monoamine oxidase (MAO), a mitochondrial enzyme involved in the degradation of biogenic amines, has been associated with psychiatric morbidity. Although twin and family studies have indicated that...
Simultaneous quantification of several mRNA species by solution hybridisation with oligonucleotides.
Daniels, J, Holmans, P, Williams, N, Turic, D, McGuffin, P, Plomin, R, ...
Allelic association studies provide the most powerful method for locating genes of small effect contributing to complex diseases and traits. However, in outbred populations, allelic association is...
Simulation of Mendelism revisited: the recessive gene for attending medical school.
Much of the recent confusion concerning studies of complex phenotypes such as neuropsychiatric disorders may derive from the inappropriate assumption of simple Mendelian transmission. This has...
McGuffin, P, Sargeant, M, Hetti, G, Tidmarsh, S, Whatley, S, Marchbanks, R M
The report of a putative schizophrenia susceptibility gene linked to markers in the chromosome 5q11-q13 region and subsequent failures of replication have provoked considerable controversy. We here...
Platelet monoamine oxidase (MAO) activity: evidence for a single major locus.
Rice, J, McGuffin, P, Goldin, L R, Shaskan, E G, Gershon, E S
Monoamine oxidase (MAO), a mitochondrial enzyme involved in the degradation of biogenic amines, has been associated with psychiatric morbidity. Although twin and family studies have indicated that...
The diagnostic interview for psychoses (DIP): development, reliability and applications
Castle, DJ, Jablensky, A, McGrath, JJ, Carr, V, Morgan, V, Waterreus, A, ...
Background. We describe the development, reliability and applications of the Diagnostic Interview for Psychoses (DIP), a comprehensive interview schedule for psychotic disorders. Method. The DIP is...
Bowen, T., Guy, C., Speight, G., Jones, L., Cardno, A., Murphy, K., ...
Studies of the transmission of schizophrenia in families with affected members in several generations have suggested that an expanded trinucleotide repeat mechanism may contribute to the genetic...