P. Murtha

Publication List Details

Period

2008 - 2008

Number

9

Co-Authors

JIBS Book Review Like much great science, the research on (2008)

P. Murtha, Stefanie Ann Lenway, Jeffrey A. Hart

which this book is based began with a premise that turned out to be false, but which in the course of investigation uncovered something much more interesting and useful. The authors had focused...

Selection and amplification of heterologous genes encoding adenosine deaminase in mammalian cells.

Kaufman, R J, Murtha, P, Ingolia, D E, Yeung, C Y, Kellems, R E

We demonstrate that an adenosine deaminase (ADA) cDNA gene can function as a dominant selectable and amplifiable marker for gene transfer experiments in mammalian cells. Cells that incorporate the...

Translational control mediated by eucaryotic initiation factor-2 is restricted to specific mRNAs in transfected cells.

Kaufman, R J, Murtha, P

The translational efficiency of mRNA molecules transcribed from plasmid DNA transfected into COS-1 monkey cells can be increased 10- to 20-fold by the coexpression of the adenovirus virus-associated...

A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity.

Toole, J J, Pittman, D D, Orr, E C, Murtha, P, Wasley, L C, Kaufman, R J

Factor VIII (antihemophilic factor) is a high molecular weight plasma glycoprotein that participates in the blood clotting cascade. The recent cloning and sequence analysis of the cDNA encoding human...

Translational efficiency of polycistronic mRNAs and their utilization to express heterologous genes in mammalian cells.

Kaufman, R J, Murtha, P, Davies, M V

The translation of polycistronic mRNAs in mammalian cells was studied. Transcription units, constructed to contain one, two or three open reading frames (ORFs), were introduced stably into Chinese...

Selection and amplification of heterologous genes encoding adenosine deaminase in mammalian cells.

Kaufman, R J, Murtha, P, Ingolia, D E, Yeung, C Y, Kellems, R E

We demonstrate that an adenosine deaminase (ADA) cDNA gene can function as a dominant selectable and amplifiable marker for gene transfer experiments in mammalian cells. Cells that incorporate the...

Translational control mediated by eucaryotic initiation factor-2 is restricted to specific mRNAs in transfected cells.

Kaufman, R J, Murtha, P

The translational efficiency of mRNA molecules transcribed from plasmid DNA transfected into COS-1 monkey cells can be increased 10- to 20-fold by the coexpression of the adenovirus virus-associated...

A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity.

Toole, J J, Pittman, D D, Orr, E C, Murtha, P, Wasley, L C, Kaufman, R J

Factor VIII (antihemophilic factor) is a high molecular weight plasma glycoprotein that participates in the blood clotting cascade. The recent cloning and sequence analysis of the cDNA encoding human...

Translational efficiency of polycistronic mRNAs and their utilization to express heterologous genes in mammalian cells.

Kaufman, R J, Murtha, P, Davies, M V

The translation of polycistronic mRNAs in mammalian cells was studied. Transcription units, constructed to contain one, two or three open reading frames (ORFs), were introduced stably into Chinese...