P. P. Pandolfi

Publication List Details

Period

1993 - 2004

Number

19

Co-Authors

The chromosome make-up of mouse embryonic stem cells is predictive of somatic and germ cell chimerism. (1997)

Longo, L., Bygrave, A., Grosveld, F.G., Pandolfi, P.P.

Mouse pluripotent embryonic stem (ES) cells, once reintroduced into a mouse blastocyst, can contribute to the formation of all tissues, including the germline, of an organism referred to as a...

Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis. (1995)

Pandolfi, P.P., Roth, M.E., Karis, A., Leonard, M.W., Dzierzak, E., Grosveld, F.G., ...

GATA-3 is one member of a growing family of related transcription factors which share a strongly conserved expression pattern in all vertebrate organisms. In order to elucidate GATA-3 function using...

Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD-null): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress. (1995)

Pandolfi, P.P., Sonati, F., Rivi, R., Mason, P., Grosveld, F.G., Luzzatto, L.

Glucose 6-phosphate dehydrogenase (G6PD) is a housekeeping enzyme encoded in mammals by an X-linked gene. It has important functions in intermediary metabolism because it catalyzes the first step in...

The acute promyelocytic leukaemia-associated PML gene is induced by interferon. (1995)

Lavau, C., Marchio, A., Fagioli, M., Jansen, J., Falini, B., Lebon, P., ...

The PML protein concentrates within discrete nuclear structures known as nuclear bodies, also called NDs or PODs, which contain several proteins including the interferon (IFN)-inducible SP100...

Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.

Alcalay, M, Zangrilli, D, Fagioli, M, Pandolfi, P P, Mencarelli, A, Lo Coco, F, ...

Two chimeric genes, PML-RAR alpha and RAR alpha-PML, are formed as a consequence of the acute promyelocytic leukemia (APL)-specific reciprocal translocation of chromosomes 15 and 17 [t(15;17)]....

Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.

Alcalay, M, Zangrilli, D, Pandolfi, P P, Longo, L, Mencarelli, A, Giacomucci, A, ...

Acute promyelocytic leukemias (APLs) are characterized by a reciprocal balanced translocation that involves chromosomes 15 and 17 [t(15;17)]. We report the isolation and characterization of one of...

Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress.

Pandolfi, P P, Sonati, F, Rivi, R, Mason, P, Grosveld, F, Luzzatto, L

Glucose 6-phosphate dehydrogenase (G6PD) is a housekeeping enzyme encoded in mammals by an X-linked gene. It has important functions in intermediary metabolism because it catalyzes the first step in...

Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion.

Rosti, V, Tremml, G, Soares, V, Pandolfi, P P, Luzzatto, L, Bessler, M

Paroxysmal nocturnal hemoglobinuria (PNH) develops in patients who have had a somatic mutation in the X-linked PIG-A gene in a hematopoietic stem cell; as a result, a proportion of blood cells are...

Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.

Pandolfi, P P, Alcalay, M, Fagioli, M, Zangrilli, D, Mencarelli, A, Diverio, D, ...

The acute promyelocytic leukaemia (APL) 15;17 translocation generates a PML/RAR alpha chimeric gene which is transcribed as a fusion PML/RAR alpha mRNA. Molecular studies on a large series of APLs...

Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.

Alcalay, M, Zangrilli, D, Fagioli, M, Pandolfi, P P, Mencarelli, A, Lo Coco, F, ...

Two chimeric genes, PML-RAR alpha and RAR alpha-PML, are formed as a consequence of the acute promyelocytic leukemia (APL)-specific reciprocal translocation of chromosomes 15 and 17 [t(15;17)]....

Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.

Alcalay, M, Zangrilli, D, Pandolfi, P P, Longo, L, Mencarelli, A, Giacomucci, A, ...

Acute promyelocytic leukemias (APLs) are characterized by a reciprocal balanced translocation that involves chromosomes 15 and 17 [t(15;17)]. We report the isolation and characterization of one of...

Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress.

Pandolfi, P P, Sonati, F, Rivi, R, Mason, P, Grosveld, F, Luzzatto, L

Glucose 6-phosphate dehydrogenase (G6PD) is a housekeeping enzyme encoded in mammals by an X-linked gene. It has important functions in intermediary metabolism because it catalyzes the first step in...

Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion.

Rosti, V, Tremml, G, Soares, V, Pandolfi, P P, Luzzatto, L, Bessler, M

Paroxysmal nocturnal hemoglobinuria (PNH) develops in patients who have had a somatic mutation in the X-linked PIG-A gene in a hematopoietic stem cell; as a result, a proportion of blood cells are...

Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.

Pandolfi, P P, Alcalay, M, Fagioli, M, Zangrilli, D, Mencarelli, A, Diverio, D, ...

The acute promyelocytic leukaemia (APL) 15;17 translocation generates a PML/RAR alpha chimeric gene which is transcribed as a fusion PML/RAR alpha mRNA. Molecular studies on a large series of APLs...