Graham, B. A., Schofield, P. R., Sah, P., Margrie, T. W., Callister, R. J.
Spastic (spa), spasmodic (spd), and oscillator (ot) mice have naturally occurring glycine receptor ( GlyR) mutations, which manifest as motor deficits and an exaggerated startle response. Using...
A Western Australian kindred with Dutch cerebral amyloid angiopathy (2005)
Panegyres, P. K., Kwok, J. B. J., Schofield, P. R., Blumbergs, Peter Charles
A Western Australian kindred with Dutch cerebral amyloid angiopathy (2005)
Panegyres, P. K., Kwok, J. B. J., Schofield, P. R., Blumbergs, Peter Charles
Autosomal dominant congenital non-progressive ataxia overlaps with the SCA15 locus (2004)
Dudding, T. E., Friend, K. L., Schofield, P. R., Lee, S., Wilkinson, I., Richards, Robert Ian
Background: Most patients with pure nonprogressive congenital cerebellar ataxia have a sporadic form of unknown heredity and etiology. Several small families have been reported with a dominantly...
Autosomal dominant congenital non-progressive ataxia overlaps with the SCA15 locus (2004)
Dudding, T. E., Friend, K. L., Schofield, P. R., Lee, S., Wilkinson, I., Richards, Robert Ian
Background: Most patients with pure nonprogressive congenital cerebellar ataxia have a sporadic form of unknown heredity and etiology. Several small families have been reported with a dominantly...
Brooks, W. S., Kwok, J. B.J., Kril, J., Broe, G. A., Blumbergs, Peter Charles, Tannenberg, A. E., ...
Brooks, W. S., Kwok, J. B.J., Kril, J., Broe, G. A., Blumbergs, Peter Charles, Tannenberg, A. E., ...
Lynch, J.W., J.L. Haddrill, K.D. Pierce, P.R. Schofield
The M2-M3 loop plays a crucial role in the activation of ligand-gated ion channels. At the time, we boldly hypothesised that this domain acts as a hinge to allow the pore-lining M2 domain to move...
Lynch, J.W., J.L. Haddrill, K.D. Pierce, P.R. Schofield
The M2-M3 loop plays a crucial role in the activation of ligand-gated ion channels. At the time, we boldly hypothesised that this domain acts as a hinge to allow the pore-lining M2 domain to move...
Lynch, J. W., Han, N., Schofield, P. R.
1, The glycine receptor chloride channel mediates inhibitory neurotransmission and is a member of the ligand-gated ion channel superfamilyl which includes the nicotinic acetylcholine receptor...
Chin, C. K., Schofield, P. R., Robertson, D. M., Gray, P. P., Chotigeat, W., Mahler, S. M.
Human follicle stimulating hormone is a pituitary glycoprotein that is essential for the maintenance of ovarian follicle development and testicular spermatogenesis. Like other members of the...
Localisation of the adenosine A1 receptor subtype gene (ADORA1) to chromosome 1q32.1 (1995)
Townsend-Nicholson, A., Baker, E., Schofield, P. R., Sutherland, G. R.
Localisation of the adenosine A1 receptor subtype gene (ADORA1) to chromosome 1q32.1 (1995)
Townsend-Nicholson, A., Baker, E., Schofield, P. R., Sutherland, G. R.
A novel GABAA receptor subunit is important for benzodiazepine pharmacology (1989)
Pritchett,D. B., Sontheimer,H., Shivers,B. D., Ymer,S., Kettenmann,H., Schofield,P. R., ...
Sequence and expression of human GABAA receptor a1 and ß1 subunits (1989)
Schofield,P. R., Pritchett,D. B., Sontheimer,H., Kettenmann,H., Seeburg,Peter H.
Two novel GABAA receptor subunits exist in distinct neuronal subpopulations (1989)
Shivers,B. D., Killisch,I., Sprengel,Rolf, Sontheimer,H., Köhler,Martin, Schofield,P. R., ...
Functional chloride channels by mammalian cell expression of rat glycine receptor subunit (1989)
Sontheimer,H., Becker,Cord-Michael, Pritchett,D. B., Schofield,P. R., Grenningloh,G., Kettenmann,H., ...
Sequence and expression of novel GABAA receptor a subunit (1989)
Ymer,S., Draguhn,Andreas, Köhler,Martin, Schofield,P. R., Seeburg,Peter H.
GABAA receptor b subunit heterogeneity: functional expression of cloned cDNAs (1989)
Ymer,S., Schofield,P. R., Draguhn,Andreas, Werner,Pia, Köhler,Martin, Seeburg,Peter H.
Cloned cDNAs encoding two new beta subunits of the rat and bovine GABAA receptor have been isolated using a degenerate oligonucleotide probe based on a highly conserved peptide sequence in the second...
Sequence and expression of novel GABAA receptor a subunit (1989)
Ymer,S., Draguhn,Andreas, Köhler,Martin, Schofield,P. R., Seeburg,Peter H.
GABAA receptor b subunit heterogeneity: functional expression of cloned cDNAs (1989)
Ymer,S., Schofield,P. R., Draguhn,Andreas, Werner,Pia, Köhler,Martin, Seeburg,Peter H.
Cloned cDNAs encoding two new beta subunits of the rat and bovine GABAA receptor have been isolated using a degenerate oligonucleotide probe based on a highly conserved peptide sequence in the second...
Buckle, V. J., Fujita, Naoyuki, Ryder-Cook, A. S., Derry, J. M. J., Barnard, Pene J., Lebo, R. V., ...
A novel GABAA receptor subunit is important for benzodiazepine pharmacology (1989)
Pritchett, D. B., Sontheimer, H., Shivers, B. D., Ymer, S., Kettenmann, H., Schofield, P. R., ...
Sequence and expression of human GABAA receptor a1 and ß1 subunits (1989)
Schofield, P. R., Pritchett, D. B., Sontheimer, H., Kettenmann, H., Seeburg, Peter H.
Two novel GABAA receptor subunits exist in distinct neuronal subpopulations (1989)
Shivers, B. D., Killisch, I., Sprengel, Rolf, Sontheimer, H., Köhler, Martin, Schofield, P. R., ...
Functional chloride channels by mammalian cell expression of rat glycine receptor subunit (1989)
Sontheimer, H., Becker, Cord-Michael, Pritchett, D. B., Schofield, P. R., Grenningloh, G., Kettenmann, H., ...
Sequence and expression of novel GABAA receptor a subunit (1989)
Ymer, S., Draguhn, Andreas, Köhler, Martin, Schofield, P. R., Seeburg, Peter H.
GABAA receptor b subunit heterogeneity: functional expression of cloned cDNAs (1989)
Ymer, S., Schofield, P. R., Draguhn, Andreas, Werner, Pia, Köhler, Martin, Seeburg, Peter H.
Cloned cDNAs encoding two new beta subunits of the rat and bovine GABAA receptor have been isolated using a degenerate oligonucleotide probe based on a highly conserved peptide sequence in the second...
Sequence and expression of novel GABAA receptor a subunit (1989)
Ymer, S., Draguhn, Andreas, Köhler, Martin, Schofield, P. R., Seeburg, Peter H.
GABAA receptor b subunit heterogeneity: functional expression of cloned cDNAs (1989)
Ymer, S., Schofield, P. R., Draguhn, Andreas, Werner, Pia, Köhler, Martin, Seeburg, Peter H.
Cloned cDNAs encoding two new beta subunits of the rat and bovine GABAA receptor have been isolated using a degenerate oligonucleotide probe based on a highly conserved peptide sequence in the second...
Molecular Biology of the GABAA receptor (1988)
Barnard,Eric A., Darlison,Mark G., Fujita,Naoyuki, Glencorse,T. A., Levitan,E. S., Reale,V., ...
Structural and functional basis for GABAA receptor heterogeneity (1988)
Levitan,E. S., Schofield,P. R., Burt,David R., Rhee,L. M., Wisden,William, Köhler,Martin, ...
Molecular Biology of the GABAA receptor (1988)
Barnard, Eric A., Darlison, Mark G., Fujita, Naoyuki, Glencorse, T. A., Levitan, E. S., Reale, V., ...
Structural and functional basis for GABAA receptor heterogeneity (1988)
Levitan, E. S., Schofield, P. R., Burt, David R., Rhee, L. M., Wisden, William, Köhler, Martin, ...
Pritchett, D. B., Sontheimer, H., Gorman, C. M., Kettenmann, H., Seeburg, Peter H., Schofield, P. R.
A novel subtype of muscarinic receptor identified by homology screening (1987)
Braun,Thomas, Schofield,P. R., Shivers,B. D., Pritchett,D. B., Seeburg,Peter H.
A new member of the protein superfamily of G-protein coupled receptors has been isolated by homology screening. By virtue of its homology with other muscarinic acetylcholine receptors and its ability...
Glycine vs GABA receptors (1987)
Grenningloh,G., Gundelfinger,E., Schmitt,B., Betz,Heinrich, Darlison,Mark G., Barnard,Eric A., ...
Molecular cloning and amino acid sequence of rat enkephalinase (1987)
Malfroy,B., Schofield,P. R., Kuang,W. J., Seeburg,Peter H., Mason,A. J., Henzel,W. J.
The brain GABA receptor: cloning and functional expression of the cDNAs encoding its subunits (1987)
Schofield,P. R., Darlison,Mark G., Fujita,Naoyuki, Rodriguez,H., Burt,David R., Stephenson,F. A., ...
A novel subtype of muscarinic receptor identified by homology screening (1987)
Braun,Thomas, Schofield,P. R., Shivers,B. D., Pritchett,D. B., Seeburg,Peter H.
A new member of the protein superfamily of G-protein coupled receptors has been isolated by homology screening. By virtue of its homology with other muscarinic acetylcholine receptors and its ability...
A novel subtype of muscarinic receptor identified by homology screening (1987)
Braun, Thomas, Schofield, P. R., Shivers, B. D., Pritchett, D. B., Seeburg, Peter H.
A new member of the protein superfamily of G-protein coupled receptors has been isolated by homology screening. By virtue of its homology with other muscarinic acetylcholine receptors and its ability...
Glycine vs GABA receptors (1987)
Grenningloh, G., Gundelfinger, E., Schmitt, B., Betz, Heinrich, Darlison, Mark G., Barnard, Eric A., ...
Molecular cloning and amino acid sequence of rat enkephalinase (1987)
Malfroy, B., Schofield, P. R., Kuang, W. J., Seeburg, Peter H., Mason, A. J., Henzel, W. J.
The brain GABA receptor: cloning and functional expression of the cDNAs encoding its subunits (1987)
Schofield, P. R., Darlison, Mark G., Fujita, Naoyuki, Rodriguez, H., Burt, David R., Stephenson, F. A., ...
A novel subtype of muscarinic receptor identified by homology screening (1987)
Braun, Thomas, Schofield, P. R., Shivers, B. D., Pritchett, D. B., Seeburg, Peter H.
A new member of the protein superfamily of G-protein coupled receptors has been isolated by homology screening. By virtue of its homology with other muscarinic acetylcholine receptors and its ability...
Vandenberg, R J, French, C R, Barry, P H, Shine, J, Schofield, P R
The inhibitory glycine receptor (GlyR) is a member of the ligand-gated ion channel receptor superfamily. Glycine activation of the receptor is antagonized by the convulsant alkaloid strychnine. Using...
The Rhizobium trifolii nod genes required for host-specific nodulation of clovers are located on 14 kb of Sym (symbiotic) plasmid DNA. Analysis of the nucleotide sequence of a 3.7 kb portion of this...
In the fast-growing Rhizobium species, repeated DNA sequences, which include the promoter region of the nif HDK operon have been described. These repeated sequences are promoters which specifically...
Rajendra, S, Vandenberg, R J, Pierce, K D, Cunningham, A M, French, P W, Barry, P H, ...
A loop structure, formed by the putative disulfide bridging of Cys198 and Cys209, is a principal element of the ligand binding site in the glycine receptor (GlyR). Disruption of the loop's tertiary...
Schofield, P R, McFarland, K C, Hayflick, J S, Wilcox, J N, Cho, T M, Roy, S, ...
A purified opioid-binding protein has been characterized by cDNA cloning. The cDNA sequence predicts an extracellularly located glycoprotein of 345 amino acids. This protein does not possess a...
Schmieden, V, Grenningloh, G, Schofield, P R, Betz, H
The inhibitory postsynaptic glycine receptor (