P. S. Bansal

Characterization and isolation of L-to-D-amino-acid-residue isomerase from platypus venom (2007)

Torres, A. M., Tsampazi, M., Kennett, E. C., Belov, K., Geraghty, D. P., Bansal, P. S., ...

Platypus venom contains an isomerase that reversibly interconverts the second amino-acid residue in some peptides between the L-form and the D-form. The enzyme acts on the natriuretic peptides OvCNPa...

The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs (2007)

Chandrashekaran, I. R., Yao, S. G., Wang, C. C., Bansal, P. S., Alewood, P. F., Forbes, B. E., ...

Insulin-like growth factor binding proteins (IGFBPs) modulate the activity and distribution of insulin-like growth factors (IGFs). IGFBP-6 differs from other IGFBPs in being a relatively specific...

Characterization and isolation of L-to-D-amino-acid-residue isomerase from platypus venom (2007)

Torres, A. M., Tsampazi, M., Kennett, E. C., Belov, K., Geraghty, D. P., Bansal, P. S., ...

Platypus venom contains an isomerase that reversibly interconverts the second amino-acid residue in some peptides between the L-form and the D-form. The enzyme acts on the natriuretic peptides OvCNPa...

The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs (2007)

Chandrashekaran, I. R., Yao, S. G., Wang, C. C., Bansal, P. S., Alewood, P. F., Forbes, B. E., ...

Insulin-like growth factor binding proteins (IGFBPs) modulate the activity and distribution of insulin-like growth factors (IGFs). IGFBP-6 differs from other IGFBPs in being a relatively specific...

A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins (2006)

Imperial, J. S., Bansal, P. S., Daly, N. L., Craik, D. ., Sporning, A., ...

Using assay-directed fractionation of the venom from the vermivorous cone snail Conus planorbis, we isolated a new conotoxin, designated p114a, with potent activity at both nicotinic acetylcholine...

Chemical synthesis and structure elucidation of bovine kappa-casein (1-44) (2006)

Bansal, P. S., Grieve, P. A., Marschke, R. J., Daly, N. L., McGhie, E., Craik, D. J., ...

The caseins (alpha(s1), alpha(s2), beta, and kappa) are phosphoproteins present in bovine milk that have been studied for over a century and whose structures remain obscure. Here we describe the...

Mammalian L-to-D-amino-acid-residue isomerase from platypus venom (2006)

Torres, A. M., Tsampazi, M., Tsampazi, C., Kennett, EC, Belov, K., Geraghty, D. P., ...

The presence Of D-amino-acid-containing polypeptides, defensin-like peptide (DLP)-2 and Ornithorhyncus venom C-type natriuretic peptide (OvCNP)b, in platypus venom suggested the existence of a...

The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold (2006)

Daly, N. L., Chen, Y. K., Foley, F. M., Bansal, P. S., Bharathi, R., Clark, R. J., ...

SFTI-1 is a small cyclic peptide from sunflower seeds that is one of the most potent trypsin inhibitors of any naturally occurring peptide and is related to the Bowman-Birk family of inhibitors...

A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins (2006)

Imperial, J. S., Bansal, P. S., Daly, N. L., Craik, D. ., Sporning, A., ...

Using assay-directed fractionation of the venom from the vermivorous cone snail Conus planorbis, we isolated a new conotoxin, designated p114a, with potent activity at both nicotinic acetylcholine...

Chemical synthesis and structure elucidation of bovine kappa-casein (1-44) (2006)

Bansal, P. S., Grieve, P. A., Marschke, R. J., Daly, N. L., McGhie, E., Craik, D. J., ...

The caseins (alpha(s1), alpha(s2), beta, and kappa) are phosphoproteins present in bovine milk that have been studied for over a century and whose structures remain obscure. Here we describe the...

Mammalian L-to-D-amino-acid-residue isomerase from platypus venom (2006)

Torres, A. M., Tsampazi, M., Tsampazi, C., Kennett, EC, Belov, K., Geraghty, D. P., ...

The presence Of D-amino-acid-containing polypeptides, defensin-like peptide (DLP)-2 and Ornithorhyncus venom C-type natriuretic peptide (OvCNP)b, in platypus venom suggested the existence of a...

The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold (2006)

Daly, N. L., Chen, Y. K., Foley, F. M., Bansal, P. S., Bharathi, R., Clark, R. J., ...

SFTI-1 is a small cyclic peptide from sunflower seeds that is one of the most potent trypsin inhibitors of any naturally occurring peptide and is related to the Bowman-Birk family of inhibitors...

Chemical synthesis and structure elucidation of bovine K-casein (1-44) (2006)

Bansal, P.S., Daly, N.L., McGhie, E., Craik, D.J., Alewood, P.F., Grieve, P., ...

The caseins (αs1, αs2, β, and κ) are phosphoproteins present in bovine milk that have been studied for over a century and whose structures remain obscure. Here we describe the chemical synthesis...

Chemical synthesis and structure elucidation of bovine K-casein (1-44) (2006)

Bansal, P.S., Daly, N.L., McGhie, E., Craik, D.J., Alewood, P.F., Grieve, P., ...

The caseins (αs1, αs2, β, and κ) are phosphoproteins present in bovine milk that have been studied for over a century and whose structures remain obscure. Here we describe the chemical synthesis...

Chemical synthesis and structure elucidation of bovine K-casein (1-44) (2006)

Bansal, P.S., Daly, N.L., McGhie, E., Craik, D.J., Alewood, P.F., Grieve, P., ...

The caseins (αs1, αs2, β, and κ) are phosphoproteins present in bovine milk that have been studied for over a century and whose structures remain obscure. Here we describe the chemical synthesis...

D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties (2005)

Torres, A. M., Tsampazi, C., Geraghty, D. P., Bansal, P. S., Alewood, P. F., Kuchel, P. W.

The recent discovery that the natriuretic peptide OvCNPb (Ornithorhynchus venom C-type natriuretic peptide B) from platypus (Ornithorynchus anatinus) venom contains a D-amino acid residue suggested...

D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties (2005)

Torres, A. M., Tsampazi, C., Geraghty, D. P., Bansal, P. S., Alewood, P. F., Kuchel, P. W.

The recent discovery that the natriuretic peptide OvCNPb (Ornithorhynchus venom C-type natriuretic peptide B) from platypus (Ornithorynchus anatinus) venom contains a D-amino acid residue suggested...

a-Conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors (2003)

Nicke, A. C., Samochocki, M., Loughnan, M. L., Bansal, P.S., Maelicke, A., Lewis, R. J.

Structure of the HERG K+ channel S5P extracellular linker - Role of an amphipathic alpha-helix in C-type inactivation (2003)

Torres, A. M., Bansal, P. S., Sunde, M., Clarke, C. E., Bursill, J. A., Smith, D. J., ...

The HERG K+ channel has very unusual kinetic behavior that includes slow activation but rapid inactivation. These features are critical for normal cardiac repolarization as well as in preventing...

Structure of the HERG K+ channel S5P extracellular linker - Role of an amphipathic alpha-helix in C-type inactivation (2003)

Torres, A. M., Bansal, P. S., Sunde, M., Clarke, C. E., Bursill, J. A., Smith, D. J., ...

The HERG K+ channel has very unusual kinetic behavior that includes slow activation but rapid inactivation. These features are critical for normal cardiac repolarization as well as in preventing...

A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity (2002)

Dutton, J. L., Bansal, P. S., Hogg, R. C., Adams, D. J., Alewood, P. F., Craik, D. J.

alpha-Conotoxin AuIB and a disulfide bond variant of AuIB have been synthesized to determine the role of disulfide bond connectivity on structure and activity. Both of these peptides contain the 15...

A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity (2002)

Dutton, J. L., Bansal, P. S., Hogg, R. C., Adams, D. J., Alewood, P. F., Craik, D. J.

alpha-Conotoxin AuIB and a disulfide bond variant of AuIB have been synthesized to determine the role of disulfide bond connectivity on structure and activity. Both of these peptides contain the 15...

The S631A Mutation Causes a Mechanistic Switch in the Block of hERG Channels by CnErg1

Hill, Adam P., Campbell, T. J., Bansal, P. S., Kuchel, P. W., Vandenberg, J. I.

We have studied the interaction of CnErg1, a member of the γ-KTX subfamily of scorpion toxins with the inactivation-deficient S631A hERG channel. In the background of this mutation, we observed a...