Specifying pancreatic endocrine cell fates. (2006)
Collombat, P., Hecksher-Soerensen, J., Serup, P., Mansouri, A.
Genetic determinants of pancreatic epsilon-cell development (2005)
Heller, R. S., Jenny, M., Collombat, P., Mansouri, A., Tomasetto, C., Madsen, O. D., ...
Opposing actions of Arx and Pax4 in endocrine pancreas development. (2003)
Collombat, P., Mansouri, A., Hecksher-Soerensen, J., Serup, P., Krull, J., Gradwohl, G., ...
Serup, P, Jensen, J, Andersen, F G, Jørgensen, M C, Blume, N, Holst, J J, ...
Insulin promoter factor 1 (IPF1), a member of the homeodomain protein family, serves an early role in pancreas formation, as evidenced by the lack of pancreas formation in mice carrying a targeted...
Petersen, H V, Serup, P, Leonard, J, Michelsen, B K, Madsen, O D
Insulin gene transcription is a unique feature of the pancreatic beta cells and is increased in response to glucose. The recent cloning of insulin promoter factor 1 (IPF1) and somatostatin...
Leonard, J, Serup, P, Gonzalez, G, Edlund, T, Montminy, M
Many eukaryotic genes are regulated by cAMP through a conserved cAMP response element (CRE). Here we show that, in the pancreatic islet cell line Tu6, a well-characterized CRE in the somatostatin...
Billestrup, N, Møldrup, A, Serup, P, Mathews, L S, Norstedt, G, Nielsen, J H
The stimulation of insulin biosynthesis in the pancreatic insulinoma cell line RIN5-AH by growth hormone (GH) is initiated by GH binding to specific receptors. To determine whether the recently...
Gelling, R. W., Du, X. Q., Dichmann, D. S., Rømer, J., Huang, H., Cui, L., ...
Glucagon, the counter-regulatory hormone to insulin, is secreted from pancreatic α cells in response to low blood glucose. To examine the role of glucagon in glucose homeostasis, mice were generated...
Serup, P, Petersen, H V, Pedersen, E E, Edlund, H, Leonard, J, Petersen, J S, ...
The mouse homeodomain protein insulin promoter factor-1 (IPF-1) and the rat homologue somatostatin transactivating factor-1 (STF-1) are involved in early pancreatic development and have been...
Conditional and specific NF-κB blockade protects pancreatic beta cells from diabetogenic agents
Eldor, R., Yeffet, A., Baum, K., Doviner, V., Amar, D., Ben-Neriah, Y., ...
Type 1 diabetes is characterized by the infiltration of inflammatory cells into pancreatic islets of Langerhans, followed by the selective and progressive destruction of insulin-secreting beta cells....
Serup, P, Jensen, J, Andersen, F G, Jørgensen, M C, Blume, N, Holst, J J, ...
Insulin promoter factor 1 (IPF1), a member of the homeodomain protein family, serves an early role in pancreas formation, as evidenced by the lack of pancreas formation in mice carrying a targeted...
Petersen, H V, Serup, P, Leonard, J, Michelsen, B K, Madsen, O D
Insulin gene transcription is a unique feature of the pancreatic beta cells and is increased in response to glucose. The recent cloning of insulin promoter factor 1 (IPF1) and somatostatin...
Leonard, J, Serup, P, Gonzalez, G, Edlund, T, Montminy, M
Many eukaryotic genes are regulated by cAMP through a conserved cAMP response element (CRE). Here we show that, in the pancreatic islet cell line Tu6, a well-characterized CRE in the somatostatin...
Billestrup, N, Møldrup, A, Serup, P, Mathews, L S, Norstedt, G, Nielsen, J H
The stimulation of insulin biosynthesis in the pancreatic insulinoma cell line RIN5-AH by growth hormone (GH) is initiated by GH binding to specific receptors. To determine whether the recently...
Gelling, R. W., Du, X. Q., Dichmann, D. S., Rømer, J., Huang, H., Cui, L., ...
Glucagon, the counter-regulatory hormone to insulin, is secreted from pancreatic α cells in response to low blood glucose. To examine the role of glucagon in glucose homeostasis, mice were generated...
Serup, P, Petersen, H V, Pedersen, E E, Edlund, H, Leonard, J, Petersen, J S, ...
The mouse homeodomain protein insulin promoter factor-1 (IPF-1) and the rat homologue somatostatin transactivating factor-1 (STF-1) are involved in early pancreatic development and have been...
Conditional and specific NF-κB blockade protects pancreatic beta cells from diabetogenic agents
Eldor, R., Yeffet, A., Baum, K., Doviner, V., Amar, D., Ben-Neriah, Y., ...
Type 1 diabetes is characterized by the infiltration of inflammatory cells into pancreatic islets of Langerhans, followed by the selective and progressive destruction of insulin-secreting beta cells....