P. Sharma

Publication List Details

Period

1900 - 2009

Number

295

Co-Authors

Laboratory diagnosis of novel H1N1 virus (2009)

Kaore, N.M, Kaore, S.N, Sharma, P., Yadav, V.K., Sharma, R.

This novel influenza virus A /H1N1 contains a combination of human, swine and avian virus genes. One of the most notable thing about this novel Influenza A/ H1N1 virus is high efficiency of human to...

Turbulence and Mixing in the Intracluster Medium (2009)

Sharma, P., Chandran, B. D. G., Quataert, E., Parrish, I. J.

The intracluster medium (ICM) is stably stratified in the hydrodynamic sense with the entropy $s$ increasing outwards. However, thermal conduction along magnetic field lines fundamentally changes the...

The origins of electromechanical indentation size effect in ferroelectrics (2009)

Gharbi, M., Sun, Z. H., Sharma, P., White, K.

Metals exhibit a size-dependent hardening when subject to indentation. Mechanisms for this phenomenon have been intensely researched in recent times. Does such a size-effect also exist in the...

Erratum: Size-dependent piezoelectricity and elasticity in nanostructures due to the flexoelectric effect[PHYSICAL REVIEW B 77, 125424 (2008)] (2009)

Majdoub, M. S., Sharma, P., Cagin, T.

This note corrects some errors in a previously published paper: Size-dependent piezoelectricity and elasticity in nanostructures due to the flexoelectric effect[PHYSICAL REVIEW B 77, 125424 (2008)]....

Atomistic determination of flexoelectric properties of crystalline dielectrics (2009)

Maranganti, R., Sharma, P.

Upon application of a uniform strain, internal sub-lattice shifts within the unit cell of a non-centrosymmetric dielectric crystal result in the appearance of a net dipole moment: a phenomenon well...

Buoyancy Instabilities in Galaxy Clusters: Convection Due to Adiabatic Cosmic Rays and Anisotropic Thermal Conduction (2009)

Sharma, P., Chandran, B. D. G., Quataert, E., Parrish, I. J.

Using a linear stability analysis and two and three-dimensional nonlinear simulations, we study the physics of buoyancy instabilities in a combined thermal and relativistic (cosmic ray) plasma,...

Proposal of biostimulation for hexachlorocyclohexane (HCH)-decontamination and characterization of culturable bacterial community from high-dose point HCH-contaminated soils (2009)

Dadhwal, M., Singh, A., Prakash, O., Gupta, S.K., Kumari, K., Sharma, P., ...

To locate a high-dose point hexachlorocyclohexane (HCH)-contaminated site, to identify HCH-degrading bacteria in it and assay HCH-decontamination by biostimulation. Methods and Results:  Bacteria...

Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis (2009)

P. Sharma, R. Kar, S. Dutta, H.P. Pati, R. Saxena

We present 2 cases of Niemann Pick disease, type B with secondary sea-blue histiocytosis. Strikingly, in both cases the Pick cells were positive for tartrate resistant acid phosphatase, a finding...

Understanding the origins of the intrinsic dead-layer effect in nanocapacitors (2008)

Majdoub, M. S., Maranganti, R., Sharma, P.

Thin films of high-permittivity dielectrics are considered ideal candidates for realizing high charge density nanosized capacitors for use in next generation energy storage and nanoelectronic...

Ceramic Drug Delivery: A Perspective (2008)

Willi Paul, Ra P. Sharma, Willi Paul, P. Sharma

ABSTRACT: Different ceramic substances are offered in the market as bone substitute materials. These include monophasic calcium phosphate ceramics of tricalciumphosphate (TCP) or hydroxyapatite (HA),...

Protein kinases of malaria parasites: an update (2008)

Doerig, C., Billker, O., Haystead, T., Sharma, P., Tobin, A.B., Waters, N.C.

Protein kinases (PKs) play crucial roles in the control of proliferation and differentiation in eukaryotic cells. Research on protein phosphorylation has expanded tremendously in the past few years,...

Nanoscale organization of hedgehog is essential for long-range signaling (2008)

Mayor , S, Sowdhamini , S, Shashidhara, R, VijayRaghavan, K. L., Vyas, N, Goswami, D. A., ...

Hedgehog (Hh) plays crucial roles in tissue-patterning and activates signaling in Patched (Ptc)-expressing cells. Paracrine signaling requires release and transport over many cell diameters away by a...

I. CHANNEL FEATURES (2008)

P. Sharma

Abstract — An autoregressive (AR) model is presented for isotropic and non-isotropic scattering environments characterized by Rice factor 0 ≤ K<∞. It is shown that at least a second order AR...

Saraca indica   leaf powder for decontamination of Pb: removal, recovery, adsorbent characterization and equilibrium modeling (2008)

Goyal, P., Sharma, P., Srivastava, S., Srivastava, M. M.

The present study explores the effectiveness of Saraca indica   leaf powder, a surplus low value agricultural waste, in removing Pb ions from aqueous solution. The influence of pH, biomass dosage,...

Saraca indica leaf powder for decontamination of Pb: removal, recovery, adsorbent characterization and equilibrium modeling (2008)

P. Goyal, P. Sharma, S. Srivastava, M. M. Srivastava

The present study explores the effectiveness of Saraca indica leaf powder, a surplus low value agricultural waste, in removing Pb ions from aqueous solution. The influence of pH, biomass dosage,...

Nonlinear Optimization of Enzyme Kinetic Parameters (2008)

M. Pant, P. Sharma, T. Radha, R.S. Sangwan, U. Roy

In the analysis of enzyme kinetics data, Km and Vmax play a very important role. Linearization of kinetic equation is still a common practice for determining these parameters. Although graphical...

4 1 (2007)

S. Kulkarni, B. Verma, P. Sharma, H. Selvaraj

In this paper, we propose a neuro-fuzzy technique for content based image retrieval. The technique is based on fuzzy interpretation of natural language, neural network learning and searching...

Specification (2007)

Status Of This, Obsoletes D. Farinacci, A. Helmy, D. Thaler, S. Deering, M. Handley, ...

This memo defines an Experimental Protocol for the Internet community. It does not specify an Internet standard of any kind. Discussion and suggestions for improvement are requested

Epidemilogical analysis of Neisseria gonorrhoeae   isolates by antimicrobial susceptibility testing, auxotyping and serotyping (2007)

Khaki, P, Bhalla, P, Sharma, P, Chawla, R, Bhalla, K

Purpose : This study was carried out to analyze the epidemiology of gonorrhea based on antimicrobial susceptibility testing, auxotyping and serotyping in New Delhi, India. Methods : Sixty gonococcal...

Kinetic Effects on Turbulence Driven by the Magnetorotational Instability in Black Hole Accretion (2007)

Sharma, P, Hammett, Greg

Magnetorotational Instability (MRI), the instability causing turbulent transport in accretion disks, is studied in the kinetic regime. Radiatively Inefficient Accretion Flows (RIAFs), like the one...

Characterization of doping levels in heteronuclear, gas-phase, van der Waals clusters and their energy absorption from an intense optical field (2006)

Jha, J., Sharma, P., Nataraju, V., Vatsa, R. K., Mathur, D., Krishnamurthy, M.

A simple mass spectrometric method has been developed to quantify dopant levels in heteronuclear clusters in the gas phase. The method is demonstrated with reference to quantification of the water...

Protein Block Expert (PBE): a web-based protein structure analysis server using a structural alphabet (2006)

Tyagi, M, Sharma, P, Swamy, CS, Cadet, F, Srinivasan, N, De Brevern, AG, ...

Encoding protein 3D structures into 1D string using short structural prototypes or structural alphabets opens a new front for structure comparison and analysis. Using the well-documented 16 motifs of...

Haloalkane Dehalogenase LinB is responsible for β- and δ-hexachlorocyclohexane transoformation in sphingobium indicum B90A (2006)

Sharma, P., Raina, V., Kumari, R., Malhotra, S., Dogra, C., Kumari, H., ...

Incubation of resting cells of Sphingobium indicum B90A, Sphingobium japonicum UT26, and Sphingobium francense Sp+ showed that they were able to transform ß- and -hexachlorocyclohexane (ß- and...

Protein Block Expert (PBE): a web-based protein structure analysis server using a structural alphabet (2006)

Tyagi, M, Sharma, P, Swamy, CS, Cadet, F, Srinivasan, N, De Brevern, AG, ...

Encoding protein 3D structures into 1D string using short structural prototypes or structural alphabets opens a new front for structure comparison and analysis. Using the well-documented 16 motifs of...

The development and validation of an endoscopic grading system for Barrett's esophagus: The Prague C & M Criteria (2006)

Sharma, P., Dent, J., Armstrong, D., Gossner, L., Hoshihara, Y., ...

Background & Aims: Barrett's esophagus (BE) is a premalignant condition for esophageal adenocarcinoma, its diagnosis relying initially on recognition of a columnar-lined distal esophagus. We aimed to...

Chemical analysis of drinking water of villages of Sanganer Tehsil, Jaipur District (2006)

P. Jain, J. D. Sharma, D. Sohu, P. Sharma

Due to pressure of human activity, urbanization and industrialization, the groundwater sources are degraded gradually; therefore pure, safe, healthy and odorless drinking water is a matter of deep...

Transdermal pharmacology of small molecule cyclic C5a antagonists (2006)

Proctor, L. M., Woodruff, T. M., Sharma, P., Shiels, I. A., Taylor, S. M.

Overproduction or underregulation of the proinflammatory complement component C5a has been implicated in numerous immune and inflammatory conditions. Therefore, targeting the C5a receptor (C5aR) has...

Transdermal pharmacology of small molecule cyclic C5a antagonists (2006)

Proctor, L. M., Woodruff, T. M., Sharma, P., Shiels, I. A., Taylor, S. M.

Overproduction or underregulation of the proinflammatory complement component C5a has been implicated in numerous immune and inflammatory conditions. Therefore, targeting the C5a receptor (C5aR) has...

Transdermal pharmacology of small molecule cyclic C5a antagonists (2006)

Proctor, L. M., Woodruff, T. M., Sharma, P., Shiels, I. A., Taylor, S. M.

Overproduction or underregulation of the proinflammatory complement component C5a has been implicated in numerous immune and inflammatory conditions. Therefore, targeting the C5a receptor (C5aR) has...

Transdermal pharmacology of small molecule cyclic C5a antagonists (2006)

Proctor, L. M., Woodruff, T. M., Sharma, P., Shiels, I. A., Taylor, S. M.

Overproduction or underregulation of the proinflammatory complement component C5a has been implicated in numerous immune and inflammatory conditions. Therefore, targeting the C5a receptor (C5aR) has...

Protein block expert (pbe): a web-based protein structure analysis server using a structural alphabet (2006)

M. Tyagi, P. Sharma, C. S. Swamy, F. Cadet, N. Srinivasan, ...

Encoding protein 3D structures into 1D string using short structural prototypes or structural alphabets opens a new front for structure comparison and analysis. Using the well-documented 16 motifs of...

Protein block expert (pbe): a web-based protein structure analysis server using a structural alphabet (2006)

M. Tyagi, P. Sharma, C. S. Swamy, F. Cadet, N. Srinivasan, ...

Encoding protein 3D structures into 1D string using short structural prototypes or structural alphabets opens a new front for structure comparison and analysis. Using the well-documented 16 motifs of...

Protein Block Expert (PBE): a web-based protein structure analysis server using a structural alphabet (2006)

Tyagi, M., Sharma, P., Swamy, C. S., Cadet, F., Srinivasan, N., De Brevern, A. G., ...

Encoding protein 3D structures into 1D string using short structural prototypes or structural alphabets opens a new front for structure comparison and analysis. Using the well-documented 16 motifs of...

SOMATIC EMBRYOGENESIS IN BUCHANANIA LANZAN SPRENG (2005)

P. SHARMA, VIJAYA KOCHE, AFAQUE QURAISHI, S. K. MISHRA

We report a protocol for somatic embryogenesis and plantlet regeneration of Buchanania lanzan Spreng (Family – Anacardiaceae), which is a tropical fruit tree widely distributed in the dry forests...

Plasma instabilities and magnetic-field growth in clusters of galaxies (2005)

Schekochihin, A. A., Cowley, S. C., Kulsrud, R. M., Hammett, G. W., Sharma, P.

We show that under very general conditions, cluster plasmas threaded by weak magnetic fields are subject to very fast growing plasma instabilities driven by the anisotropy of the plasma pressure...

Homocysteine and stroke: evidence on a causal link from mendelian randomisation (2005)

Casas, J.P., Bautista, L.E., Smeeth, L., Sharma, P., Hingorani, A.D.

Background: Individuals homozygous for the T allele of the MTHFR C677T polymorphism have higher plasma homocysteine concentrations (the phenotype) than those with the CC genotype, which, if...

Time-Series Model for Wireless Fading Channels in Isotropic and Non-Isotropic Scattering Environments (2005)

Sharma, P

An autoregressive (AR) model is presented for isotropic and non-isotropic scattering environments characterized by Rice factor 0 \leq K < \infty. It is shown that at least a second order AR process...

Time-Series Model for Wireless Fading Channels in Isotropic and Non-Isotropic Scattering Environments (2005)

Sharma, P

An autoregressive (AR) model is presented for isotropic and non-isotropic scattering environments characterized by Rice factor 0 \leq K < \infty. It is shown that at least a second order AR process...

Genetic variability of begomoviruses associated with cotton leaf curl disease originating from India (2004)

Kirthi, N, Priyadarshini, CGP, Sharma, P, Maiya, SP, Hemalatha, V, Sivaraman, P, ...

Cotton leaf curl disease (CLCuD) causing viruses belong to the Begomovirus genus of the family Geminiviridae. Most begomoviruses are bipartite with two molecules of circular single stranded DNA (A...

Magnetization and Spin-Diffusion of Liquid 3He in Aerogel (2004)

Sauls, J. A., Bunkov, Yu. M., Collin, E., Godfrin, H., Sharma, P.

We report theoretical calculations of the normal-state spin diffusion coefficient of 3He in aerogel, including both elastic and inelastic scattering of 3He quasiparticles, and compare these results...

Specific Heat of Disordered Superfluid $^{3}$He (2004)

Choi, H., Yawata, K., Haard, T. M., Davis, J. P., Gervais, G., Mulders, N., ...

The specific heat of superfluid $^{3}$He, disordered by a silica aerogel, is found to have a sharp discontinuity marking the thermodynamic transition to superfluidity at a temperature reduced from...

Variable responses of western US glaciers during the last deglaciation (2004)

Licciardi, J. M., Clark, P. U., Brook, E. J., Elmore, D., Sharma, P.

Cosmogenic Be-10 exposure ages from moraines in the Wallowa Mountains, Oregon, identify two maximal late Pleistocene glaciations at 21.1 +/- 0.4 ka and 17.0 +/- 0.3 ka and a minor glacial event at...

Genetic variability of begomoviruses associated with cotton leaf curl disease originating from India (2004)

Kirthi, N, Priyadarshini, CGP, Sharma, P, Maiya, SP, Hemalatha, V, Sivaraman, P, ...

Cotton leaf curl disease (CLCuD) causing viruses belong to the Begomovirus genus of the family Geminiviridae. Most begomoviruses are bipartite with two molecules of circular single stranded DNA (A...

Selection of Diversity and Modulation Parameters for Nakagami Fading Channels to Jointly Satisfy Outage and Bit Error Requiwments (2004)

Sharma, P

Outage is an event of instantaneous signal-to-noise ratio OR bit error rate falling in an unacceptable operational regime, Outage perfomance analysis is traditionally carried out for different...

Selection of Diversity and Modulation Parameters for Nakagami Fading Channels to Jointly Satisfy Outage and Bit Error Requiwments (2004)

Sharma, P

Outage is an event of instantaneous signal-to-noise ratio OR bit error rate falling in an unacceptable operational regime, Outage perfomance analysis is traditionally carried out for different...

Nanoscale organization of multiple GPI-anchored proteins in living cell membranes (2004)

Gousset , K, Krishnamoorthy, G, Rao, M, Mayor, S, Varma, R, Sarasij, R. C, ...

Cholesterol and sphingolipid-enriched "rafts" have long been proposed as platforms for the sorting of specific membrane components including glycosyl-phosphatidylinositol-anchored proteins (GPI-APs),...

All-optical switching with bacteriorhodopsin (2003)

Roy, S., Sharma, P., Dharmadhikari, A. K., Mathur, D.

All-optical, mirrorless switching and bistability is demonstrated with bacteriorhodopsin (bR). A low-power, 532 nm laser beam modulates the transmission of a cw laser beam at 635 nm that corresponds...

Human CRP gene polymorphism influences CRP levels - implications for the prediction and pathogenesis of coronary heart disease (2003)

Brull, D.J., Serrano, N., Zito, F., Jones, L., Montgomery, H.E., Rumley, A., ...

Objective - C- reactive protein ( CRP) concentrations are predictive of cardiovascular disease, and levels are heritable, in part. We identified novel polymorphisms in the CRP gene and assessed their...

Combined Optimal Price and Optimal Inventory Ordering Policy with Income Elasticity سياسة العروض المشتركة للكلفة المثلى والجرد الأمثل في ظل مرونة العائد (2000)

R. BHANDARI, P. SHARMA

In the present paper, the effect of income elasticity on demand has been considered and the buyer?s optimal special order quantity and optimal time has been determined, when supplier reduces sale...

A Single Period Inventory Problem with Quadratic Demand Distribution under the Influence of Marketing Policies مشكلة الجرد أحادية الفترة مع التوزيع التربيعي للطلب في ظل أثر سياسات التسويق (2000)

R. BHANDARI, P. SHARMA

A single-period inventory problem is considered where demand is taken to be quadratic in nature. The model contains usual ingredients of a newsboy problem: sale price, purchase cost, salvage value...

Influence Of Landscape Structure On Kangaroo Abundance In A Disturbed Semi-Arid Woodland Of Queensland (1999)

Mc Alpine, C. A., Grigg, G. C., Mott, J. J., Sharma, P.

This paper develops a hierarchical landscape approach for investigating how landscape structure influences the abundance of eastern grey kangaroos, red kangaroos and common wallaroos on properties in...

Influence of landscape structure on Kangaroo abundance in a disturbed semi-arid woodland of Queensland (1999)

Mcalpine, C. A., Grigg, G. C., Mott, J. J., Sharma, P.

This paper develops a hierarchical landscape approach for investigating how landscape structure influences the abundance of eastern grey kangaroos, red kangaroos and common wallaroos on properties in...

Influence of landscape structure on Kangaroo abundance in a disturbed semi-arid woodland of Queensland (1999)

McAlpine, CA, Grigg, GC, Mott, JJ, Sharma, P

This paper develops a hierarchical landscape approach for investigating how landscape structure influences the abundance of eastern grey kangaroos, red kangaroos and common wallaroos on properties in...

Influence of landscape structure on Kangaroo abundance in a disturbed semi-arid woodland of Queensland (1999)

Mcalpine, C. A., Grigg, G. C., Mott, J. J., Sharma, P.

This paper develops a hierarchical landscape approach for investigating how landscape structure influences the abundance of eastern grey kangaroos, red kangaroos and common wallaroos on properties in...

An Economic Elliptic Equation Solver for Rectangular Regions طريقة اقتصادية لحل المعادلة الإهليليجية للمناطق المستطلية الشكل (1999)

P. SHARMA, MANOJ AGARWAL

An algorithm is presented which solves the system of simultaneous linear equations generated after the application of finite differences to the elliptic equation for rectangular regions. The...

Protocol independent multicast-sparse mode (PIM-SM): Protocol specification (1998)

D. Farinacci, A. Helmy, D. Thaler, S. Deering, M. Handley, V. Jacobson, ...

community. This memo does not specify an Internet standard of any kind. Discussion and suggestions for improvement are requested. Distribution of this memo is unlimited. Acknowledgements The author...

Protocol independent multicast-sparse mode (PIM-SM): Protocol specification (1998)

D. Farinacci, A. Helmy, D. Thaler, S. Deering, M. Handley, V. Jacobson, ...

This memo defines an Experimental Protocol for the Internet community. This memo does not specify an Internet standard of any kind. Discussion and suggestions for improvement are requested....

Specification (1998)

Obsoletes D. Farinacci, A. Helmy, D. Thaler, S. Deering, M. Handley, V. Jacobson, ...

This memo defines an Experimental Protocol for the Internet community. It does not specify an Internet standard of any kind. Discussion and suggestions for improvement are requested. Distribution of...

Mapping kangaroo and euro habitat structure at a property scale using vegetation survey and Thematic Mapper data (1998)

McAlpine, C. A., Mott, J. J., Sharma, P.

The close proximity of tree and shrub cover to pastures is an important factor influencing the density and distribution of eastern grey kangaroos, red kangaroos and wallaroos in Queensland's...

Behaviour of aluminium, silicon and iron in Tapi Estuary (1995)

Sharma, P., Zingde, M.D.

Behaviour od dissolved Al, Si and Fe in high energy and well-mixed Tapi Estuary in Maharashtra, India was studied under varied tidal cycles. The observed trend of variation in concentration of...

Seawater intrusion and behaviour of dissolved boron, fluoride, calcium, magnesium and nutrients in Vashisti Estuary (1995)

Zingde, M.D., Ram, A., Sharma, P., Abidi, S.A.H.

Behaviour of dissolved B, F, Ca, Mg and nutrients in partially stratified estuary of Vashiti River, Karnataka, India has been studied under stable conditions of riverine flow. The dominance of Mg...

A general method for the synthesis of 3'-sulfhydryl and phosphate group containing oligonucleotides (1991)

Gupta, K.C., Sharma, P., Kumar, P., Sathyanarayana, S.

The syntheses are described of polymer supports useful for the synthesis of 3′-partially protected sulfhydryl, free sulfhydryl or phosphate group containing oligonucleotides. The supports are...

How to Optimize Raw Materials Storage Space Requirements. (1988)

Harhalakis, G., Sharma, P.

Storage space is an expensive "Resource." Timely planning, accurate estimation and efficient utilization of storage space for raw materials in manufacturing industry are both necessary and...

A Dynamic Planning and Control System for Inventories of Raw Materials. (1988)

Harhalakis, G., Sharma, P.

Interfaces with operational MRP II systems can realize substantial benefits in warehousing management and control. This paper presents the design, development, programming and implementation of an...

How to Optimize Raw Materials Storage Space Requirements. (1988)

Harhalakis, George, Sharma, P.

Storage space is an expensive "Resource." Timely planning, accurate estimation and efficient utilization of storage space for raw materials in manufacturing industry are both necessary and...

A Dynamic Planning and Control System for Inventories of Raw Materials. (1988)

Harhalakis, George, Sharma, P.

Interfaces with operational MRP II systems can realize substantial benefits in warehousing management and control. This paper presents the design, development, programming and implementation of an...

THE EFFECT OF NONMETAL-METAL TRANSITION DUE TO DOPING ON LATTICE THERMAL CONDUCTIVITY : APPLICATION TO Ge-DOPED InSb (1981)

Sharma, P., Roy, K., Radhakrishnan, V.

In this work we explain the phonon thermal conductivity results of Ge-doped InSb from 2 to 50 K for impurity concentrations 7.2x1017 and 5.0x1017 cm-3. Since these lie in the intermediate...

THE EFFECT OF NONMETAL-METAL TRANSITION DUE TO DOPING ON LATTICE THERMAL CONDUCTIVITY : APPLICATION TO Ge-DOPED InSb (1981)

Sharma, P., Roy, K., Radhakrishnan, V.

In this work we explain the phonon thermal conductivity results of Ge-doped InSb from 2 to 50 K for impurity concentrations 7.2x1017 and 5.0x1017 cm-3. Since these lie in the intermediate...

THE EFFECT OF NONMETAL-METAL TRANSITION DUE TO DOPING ON LATTICE THERMAL CONDUCTIVITY : APPLICATION TO Ge-DOPED InSb (1981)

Sharma, P., Roy, K., Radhakrishnan, V.

In this work we explain the phonon thermal conductivity results of Ge-doped InSb from 2 to 50 K for impurity concentrations 7.2x1017 and 5.0x1017 cm-3. Since these lie in the intermediate...

CLINICAL EVALUATION OF DIAZEPAM FOR RELIEF OF POSTOPERATIVE PAIN (1981)

SINGH, P. N., SHARMA, P., GUPTA, P. K., PANDY, K.

A double-blind trial was undertaken to compare the effects of trimeprazine tartrate (2mgkg–1 or 4mgkg–1) plus atropine 0.03mgkg–1 for oral preinedication of 192 children undergoing...

Human CRP gene polymorphism influences CRP levels - implications for the prediction and pathogenesis of coronary heart disease

Brull, D.J., Serrano, N., Zito, F., Jones, L., Montgomery, H.E., Rumley, A., ...

Objective - C- reactive protein ( CRP) concentrations are predictive of cardiovascular disease, and levels are heritable, in part. We identified novel polymorphisms in the CRP gene and assessed their...

A conserved peptide sequence of the Plasmodium falciparum circumsporozoite protein and antipeptide antibodies inhibit Plasmodium berghei sporozoite invasion of Hep-G2 cells and protect immunized mice against P. berghei sporozoite challenge.

Chatterjee, S, Wery, M, Sharma, P, Chauhan, V S

Minutes after injection into the circulation, malaria sporozoites enter hepatocytes. The speed and specificity of the invasion process suggest that it is receptor mediated. The region II sequence of...

Mechanisms of microbial movement in subsurface materials.

Reynolds, P J, Sharma, P, Jenneman, G E, McInerney, M J

The biological factors important in the penetration of Escherichia coli through anaerobic, nutrient-saturated, Ottawa sand-packed cores were studied under static conditions. In cores saturated with...

A general method for the synthesis of 3'-sulfhydryl and phosphate group containing oligonucleotides.

Gupta, K C, Sharma, P, Kumar, P, Sathyanarayana, S

The syntheses are described of polymer supports useful for the synthesis of 3'-partially protected sulfhydryl, free sulfhydryl or phosphate group containing oligonucleotides. The supports are...

Involvement of calcium in modulation of neutrophil function by phorbol esters that activate protein kinase C isotypes and related enzymes.

Merritt, J E, Moores, K E, Evans, A T, Sharma, P, Evans, F J, MacPhee, C H

In this study, the effects of a series of phorbol esters with different spectra of biological activities and different patterns of activation of the isoenzymes of protein kinase C (PKC) have been...

Cytoplasmic interactions between phospholamban residues 1-20 and the calcium-activated ATPase of the sarcoplasmic reticulum.

Sharma, P, Patchell, V B, Gao, Y, Evans, J S, Levine, B A

Phospholamban regulates the activity of the calcium-activated ATPase (CaATPase) of cardiac sarcoplasmic reticulum. Equilibrium fluorescence studies have shown that the N-terminal cytoplasmic region...

Human airway epithelial cell determinants of survival and functional phenotype for primary human mast cells

Hsieh, F. H., Sharma, P., Gibbons, A., Goggans, T., Erzurum, S. C., Haque, S. J.

Mast cells (MCs) are found in increased numbers at airway mucosal surfaces in asthmatic patients. Because human airway epithelial cells (HAECs) actively participate in airway inflammatory responses...

Protein Block Expert (PBE): a web-based protein structure analysis server using a structural alphabet

Tyagi, M., Sharma, P., Swamy, C. S., Cadet, F., Srinivasan, N., De Brevern, A. G., ...

Encoding protein 3D structures into 1D string using short structural prototypes or structural alphabets opens a new front for structure comparison and analysis. Using the well-documented 16 motifs of...

Human CRP gene polymorphism influences CRP levels - implications for the prediction and pathogenesis of coronary heart disease

Brull, D.J., Serrano, N., Zito, F., Jones, L., Montgomery, H.E., Rumley, A., ...

Objective - C- reactive protein ( CRP) concentrations are predictive of cardiovascular disease, and levels are heritable, in part. We identified novel polymorphisms in the CRP gene and assessed their...

Influence Of Landscape Structure On Kangaroo Abundance In A Disturbed Semi-Arid Woodland Of Queensland

Mc Alpine, C. A., Grigg, G. C., Mott, J. J., Sharma, P.

This paper develops a hierarchical landscape approach for investigating how landscape structure influences the abundance of eastern grey kangaroos, red kangaroos and common wallaroos on properties in...

Transdermal pharmacology of small molecule cyclic C5a antagonists

Proctor, LM, Woodruff, TM, Sharma, P, Shiels, IA, Taylor, SM

Overproduction or underregulation of the proinflammatory complement component C5a has been implicated in numerous immune and inflammatory conditions. Therefore, targeting the C5a receptor (C5aR) has...

Relative risk of dysplasia for patients with intestinal metaplasia in the distal oesophagus and in the gastric cardia

Sharma, P, Weston, A, Morales, T, Topalovski, M, Mayo, M, Sampliner, R

BACKGROUND—Biopsy specimens obtained from the gastro-oesophageal junction can reveal intestinal metaplasia in patients presenting for routine upper endoscopy. The site of biopsy may play a critical...

Magnification chromoendoscopy for the detection of intestinal metaplasia and dysplasia in Barrett’s oesophagus

Sharma, P, Weston, A P, Topalovski, M, Cherian, R, Bhattacharyya, A, Sampliner, R E

Background: The presence of intestinal metaplasia (IM) in the columnar lined distal oesophagus defines Barrett’s oesophagus with the risk of future malignant transformation. The distribution of...

Reduced complement-mediated immune complex solubilization in leprosy patients.

Ramanathan, V D, Sharma, P, Ramu, G, Sengupta, U

The ability of sera from leprosy patients to solubilize immune precipitates in vitro through the complement system was studied. The solubilizing capacity of sera from patients who did not have any...

Intracellular expression of Mycobacterium tuberculosis-specific 10-kDa antigen down-regulates macrophage B7·1 expression and nitric oxide release

SINGH, B, SINGH, G, TRAJKOVIC, V, SHARMA, P

To explore the role of the 10-kDa Mycobacterium tuberculosis-specific secreted antigen (MTSA-10 or CFP-10) in modulation of macrophage function, J774 macrophages were transfected stably with DNA...

What is the best management strategy for high grade dysplasia in Barrett’s oesophagus? A cost effectiveness analysis

Shaheen, N J, Inadomi, J M, Overholt, B F, Sharma, P

Background: Multiple treatment strategies for subjects with high grade dysplasia (HGD) in Barrett’s oesophagus (BO) have been suggested. However, it is unclear which of these strategies provides...

Huntington's disease: a molecular genetic and CT comparison.

Sharma, P, Savy, L, Britton, J, Taylor, R, Howick, A, Patton, M

Huntington's disease is a progressive neurodegenerative disease in which the molecular abnormality has recently been described. Before the availability of this molecular marker diagnosis depended on...

Description of a simple test for CADASIL disease and determination of mutation frequencies in sporadic ischaemic stroke and dementia patients

Wang, T., Sharma, S., Fox, N., Rossor, M., Brown, M., Sharma, P.

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare inherited adult onset disease characterised most commonly by cerebral ischaemic events...

Meta-analysis of the ACE gene in ischaemic stroke

Sharma, P.

OBJECTIVES—The angiotensin-1 converting enzyme (ACE) gene is known to have two polymorphic alleles I/D. People with the DD genotype have been shown to be at greater risk of myocardial infarction,...

Intestinal permeability is increased in bronchial asthma

Hijazi, Z, Molla, A, Al-Habashi, H, Muawad, W, Molla, A, Sharma, P

Background: Increased intestinal permeability has been reported in one study of adult asthmatics.

Transduodenal sphincterotomy for stenosing papillitis and massive choledocholithiasis after Billroth II gastrectomy.

Sharma, P., Klaasen, H., Skeidsvoll, H., Peirzynowski, S., Blix, I.

Management of stenosing papillitis with massive cholecystodocholithiasis in patients previously operated upon with a Billroth II (B-II) type gastrectomy, is a challenging clinical problem. Endoscopic...

The impact of hearing on communication

Fook, L., Morgan, R., Sharma, P., Adekoke, A., Turnbull, C.

The study was designed to assess the impact of hearing impairment on communication between older hospital patients and medical staff and to see whether intervention to improve hearing influences...

Neurovascular lessons from a pair of identical twins with cerebral aneurysms

Sharma, P, Brown, M

A pair of hypertensive identical twins are reported, one of whom was non-compliant with her antihypertension medication, and after a subarachnoid haemorrhage was found to have multiple cerebral...

Circadian function in patients with advanced non-small-cell lung cancer

Levin, R D, Daehler, M A, Grutsch, J F, Quiton, J, Lis, C G, Peterson, C, ...

This study aimed to evaluate whether patients with advanced non-small-cell lung cancer experience disrupted rest–activity daily rhythms, poor sleep quality, weakness, and maintain attributes that...

Deregulation of MUC4 in gastric adenocarcinoma: potential pathobiological implication in poorly differentiated non-signet ring cell type gastric cancer

Senapati, S, Chaturvedi, P, Sharma, P, Venkatraman, G, Meza, J L, El-Rifai, W, ...

MUC4 is a large, heavily glycosylated transmembrane mucin, that is implicated in the pathogenesis of various types of cancers. To date, no extensive study has been done to check the expression and...